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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | 1-trans-delta-9-Tetrahydrocannabinol |
CASRN: | ="1972-08-3" |
Study Number: | C56371B |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | |
TDMS Number: | 0521401 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (MG/KG) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 16 |
514 |
50 |
|
113 |
|
Day 34 |
480 |
50 |
|
127.2 |
|
Day 106 |
453 |
25 |
|
200.2 |
|
Day 276 |
404 |
12.5 |
|
160.3 |
|
Day 365 |
338 |
0 |
|
231.6 |
|
Day 374 |
337 |
0 |
|
219.8 |
|
Day 405 |
329 |
0 |
|
293.8 |
|
Day 426 |
423 |
25 |
|
210.8 |
|
Day 435 |
326 |
0 |
|
239.4 |
|
Day 435 |
342 |
0 |
|
217 |
|
Day 441 |
506 |
50 |
|
228.4 |
|
Day 449 |
531 |
50 |
|
220.6 |
|
Day 454 |
315 |
0 |
|
298.4 |
|
Day 454 |
352 |
0 |
|
269.2 |
|
Day 454 |
393 |
12.5 |
|
223.6 |
|
Day 454 |
412 |
12.5 |
|
221.2 |
|
Day 454 |
451 |
25 |
|
203.6 |
|
Day 454 |
470 |
25 |
|
204.2 |
|
Day 454 |
482 |
50 |
|
160.2 |
|
Day 454 |
503 |
50 |
|
225.4 |
|
Day 454 |
518 |
50 |
|
239.4 |
|
Day 455 |
300 |
0 |
|
250.8 |
|
Day 455 |
347 |
0 |
|
265.4 |
|
Day 455 |
386 |
12.5 |
|
205.8 |
|
Day 455 |
411 |
12.5 |
|
220.4 |
|
Day 455 |
425 |
25 |
|
226 |
|
Day 455 |
445 |
25 |
|
253.6 |
|
Day 455 |
481 |
50 |
|
186.8 |
|
Day 455 |
500 |
50 |
|
190.2 |
|
Day 456 |
331 |
0 |
|
267.6 |
|
Day 456 |
343 |
0 |
|
326.6 |
|
Day 456 |
364 |
12.5 |
|
233.4 |
|
Day 456 |
384 |
12.5 |
|
245.8 |
|
Day 456 |
420 |
25 |
|
217.6 |
|
Day 456 |
433 |
25 |
|
222.8 |
|
Day 456 |
476 |
50 |
|
214.8 |
|
Day 456 |
492 |
50 |
|
241.6 |
|
Day 457 |
320 |
0 |
|
243.6 |
|
Day 457 |
325 |
0 |
|
294.2 |
|
Day 457 |
388 |
12.5 |
|
200.4 |
|
Day 457 |
400 |
12.5 |
|
202.4 |
|
Day 457 |
441 |
25 |
|
223.2 |
|
Day 457 |
472 |
25 |
|
197.2 |
|
Day 457 |
513 |
50 |
|
210.4 |
|
Day 457 |
521 |
50 |
|
240 |
|
Day 458 |
303 |
0 |
|
304 |
|
Day 458 |
378 |
12.5 |
|
221.4 |
|
Day 458 |
467 |
25 |
|
207.4 |
|
Day 458 |
487 |
50 |
|
199.4 |
|
Day 458 |
508 |
50 |
|
229.6 |
|
Day 490 |
499 |
50 |
|
165 |
|
Day 509 |
428 |
25 |
|
167 |
|
Day 516 |
317 |
0 |
|
247 |
|
Day 524 |
318 |
0 |
|
256.8 |
|
Day 528 |
355 |
0 |
|
326.6 |
|
Day 534 |
299 |
0 |
|
284 |
|
Day 534 |
365 |
12.5 |
|
172.4 |
|
Day 546 |
305 |
0 |
|
207.2 |
|
Day 558 |
374 |
12.5 |
|
203.2 |
|
Day 562 |
438 |
25 |
|
197 |
|
Day 565 |
375 |
12.5 |
|
191.4 |
|
Day 576 |
312 |
0 |
|
274.4 |
|
Day 584 |
371 |
12.5 |
|
203 |
|
Day 588 |
520 |
50 |
|
211 |
|
Day 590 |
298 |
0 |
|
311.2 |
|
Day 590 |
313 |
0 |
|
318.6 |
|
Day 590 |
380 |
12.5 |
|
225.4 |
|
Day 602 |
509 |
50 |
|
262.6 |
|
Day 605 |
465 |
25 |
|
339.6 |
|
Day 612 |
479 |
50 |
|
204.4 |
|
Day 619 |
390 |
12.5 |
|
263.8 |
|
Day 620 |
348 |
0 |
|
250.8 |
|
Day 623 |
446 |
25 |
|
241.4 |
|
Day 626 |
349 |
0 |
|
233 |
|
Day 626 |
353 |
0 |
|
210.4 |
|
Day 628 |
416 |
25 |
|
238.2 |
|
Day 628 |
515 |
50 |
|
218.2 |
|
Day 632 |
307 |
0 |
|
348 |
|
Day 632 |
322 |
0 |
|
328.6 |
|
Day 633 |
350 |
0 |
|
342.6 |
|
Day 637 |
296 |
0 |
|
420.4 |
|
Day 638 |
306 |
0 |
|
224.8 |
|
Day 638 |
486 |
50 |
|
344.8 |
|
Day 639 |
444 |
25 |
|
193.5 |
|
Day 639 |
457 |
25 |
|
241.4 |
|
Day 639 |
495 |
50 |
|
210.2 |
|
Day 644 |
426 |
25 |
|
256.4 |
|
Day 645 |
345 |
0 |
|
243.2 |
|
Day 647 |
319 |
0 |
|
341.4 |
|
Day 647 |
434 |
25 |
|
202 |
|
Day 650 |
414 |
12.5 |
|
266 |
|
Day 650 |
448 |
25 |
|
280.2 |
|
Day 651 |
493 |
50 |
|
204.2 |
|
Day 651 |
498 |
50 |
|
288.2 |
|
Day 656 |
437 |
25 |
|
189.6 |
|
Day 656 |
525 |
50 |
|
219.2 |
|
Day 659 |
373 |
12.5 |
|
280.8 |
|
Day 659 |
478 |
50 |
|
210.8 |
|
Day 659 |
512 |
50 |
|
303 |
|
Day 661 |
304 |
0 |
|
230.6 |
|
Day 661 |
435 |
25 |
|
199.4 |
|
Day 676 |
321 |
0 |
|
300.4 |
|
Day 681 |
330 |
0 |
|
268 |
|
Day 681 |
399 |
12.5 |
|
235 |
|
Day 694 |
339 |
0 |
|
217.8 |
|
Day 694 |
442 |
25 |
|
229 |
|
Day 696 |
429 |
25 |
|
291.2 |
|
Day 701 |
368 |
12.5 |
|
277.2 |
|
Day 715 |
432 |
25 |
|
224.4 |
|
Day 717 |
527 |
50 |
|
214.2 |
|
Day 721 |
424 |
25 |
|
253.6 |
|
Day 724 |
297 |
0 |
|
210.4 |
|
Day 725 |
383 |
12.5 |
|
266.2 |
|
Day 725 |
391 |
12.5 |
|
218.2 |
|
Day 725 |
409 |
12.5 |
|
307.6 |
|
Day 725 |
452 |
25 |
|
273.4 |
|
Day 725 |
462 |
25 |
|
279.6 |
|
Day 725 |
473 |
25 |
|
283 |
|
Day 725 |
483 |
50 |
|
287.4 |
|
Day 725 |
497 |
50 |
|
267.4 |
|
Day 725 |
522 |
50 |
|
292.8 |
|
Day 726 |
361 |
12.5 |
|
271.8 |
|
Day 726 |
392 |
12.5 |
|
263.6 |
|
Day 726 |
408 |
12.5 |
|
286.4 |
|
Day 726 |
450 |
25 |
|
318 |
|
Day 726 |
466 |
25 |
|
275.2 |
|
Day 726 |
469 |
25 |
|
254.6 |
|
Day 726 |
491 |
50 |
|
279.6 |
|
Day 726 |
501 |
50 |
|
279 |
|
Day 726 |
502 |
50 |
|
296.4 |
|
Day 726 |
510 |
50 |
|
285.8 |
|
Day 728 |
377 |
12.5 |
|
337.6 |
|
Day 729 |
511 |
50 |
|
188 |
|
Day 731 |
358 |
12.5 |
|
294 |
|
Day 731 |
360 |
12.5 |
|
|
|
Day 731 |
363 |
12.5 |
|
264.6 |
|
Day 731 |
366 |
12.5 |
|
290.6 |
|
Day 731 |
379 |
12.5 |
|
267 |
|
Day 731 |
381 |
12.5 |
|
270.4 |
|
Day 731 |
385 |
12.5 |
|
280.6 |
|
Day 731 |
387 |
12.5 |
|
302.2 |
|
Day 731 |
389 |
12.5 |
|
254.4 |
|
Day 731 |
394 |
12.5 |
|
301.8 |
|
Day 731 |
402 |
12.5 |
|
248 |
|
Day 731 |
405 |
12.5 |
|
248.8 |
|
Day 731 |
406 |
12.5 |
|
317 |
|
Day 731 |
407 |
12.5 |
|
306.4 |
|
Day 731 |
410 |
12.5 |
|
251.4 |
|
Day 731 |
417 |
25 |
|
289.2 |
|
Day 731 |
421 |
25 |
|
284 |
|
Day 731 |
422 |
25 |
|
272.8 |
|
Day 731 |
427 |
25 |
|
301.4 |
|
Day 731 |
430 |
25 |
|
290.6 |
|
Day 731 |
431 |
25 |
|
261.4 |
|
Day 731 |
436 |
25 |
|
252.8 |
|
Day 731 |
440 |
25 |
|
222.2 |
|
Day 731 |
455 |
25 |
|
304.8 |
|
Day 731 |
458 |
25 |
|
254.8 |
|
Day 731 |
460 |
25 |
|
283.8 |
|
Day 731 |
463 |
25 |
|
283.6 |
|
Day 731 |
471 |
25 |
|
301.8 |
|
Day 731 |
474 |
25 |
|
283.2 |
|
Day 731 |
475 |
25 |
|
265 |
|
Day 731 |
477 |
50 |
|
318.8 |
|
Day 731 |
484 |
50 |
|
245.4 |
|
Day 731 |
485 |
50 |
|
308.2 |
|
Day 731 |
490 |
50 |
|
308.6 |
|
Day 731 |
496 |
50 |
|
285.4 |
|
Day 731 |
505 |
50 |
|
256.4 |
|
Day 731 |
516 |
50 |
|
311.4 |
|
Day 731 |
517 |
50 |
|
294.8 |
|
Day 731 |
519 |
50 |
|
324 |
|
Day 731 |
524 |
50 |
|
259.4 |
|
Day 731 |
526 |
50 |
|
273.2 |
|
Day 731 |
528 |
50 |
|
362.2 |
|
Day 731 |
529 |
50 |
|
265.6 |
|
Day 731 |
530 |
50 |
|
238.2 |
|
Day 731 |
533 |
50 |
|
260.8 |
|
Day 735 |
454 |
25 |
|
263.6 |
|
Day 735 |
494 |
50 |
|
285.2 |
|
Day 736 |
301 |
0 |
|
287.6 |
|
Day 736 |
302 |
0 |
|
302.4 |
|
Day 736 |
308 |
0 |
|
204.2 |
|
Day 736 |
309 |
0 |
|
323.6 |
|
Day 736 |
310 |
0 |
|
290.2 |
|
Day 736 |
311 |
0 |
|
251.4 |
|
Day 736 |
314 |
0 |
|
351.2 |
|
Day 736 |
316 |
0 |
|
219 |
|
Day 736 |
323 |
0 |
|
311.8 |
|
Day 736 |
324 |
0 |
|
311.2 |
|
Day 736 |
327 |
0 |
|
299.4 |
|
Day 736 |
328 |
0 |
|
359 |
|
Day 736 |
332 |
0 |
|
275.8 |
|
Day 736 |
333 |
0 |
|
312.2 |
|
Day 736 |
334 |
0 |
|
321.2 |
|
Day 736 |
335 |
0 |
|
317.8 |
|
Day 736 |
336 |
0 |
|
298.4 |
|
Day 736 |
340 |
0 |
|
326.6 |
|
Day 736 |
341 |
0 |
|
328 |
|
Day 736 |
344 |
0 |
|
324.4 |
|
Day 736 |
346 |
0 |
|
347 |
|
Day 736 |
351 |
0 |
|
339.8 |
|
Day 736 |
354 |
0 |
|
315.2 |
|
Day 736 |
370 |
12.5 |
|
246.8 |
|
Day 736 |
376 |
12.5 |
|
224.2 |
|
Day 736 |
403 |
12.5 |
|
244.2 |
|
Day 736 |
439 |
25 |
|
254.8 |
|
Day 736 |
456 |
25 |
|
258.4 |
|
Day 736 |
523 |
50 |
|
282.8 |
|
Day 736 |
532 |
50 |
|
263.8 |
|
Day 737 |
356 |
12.5 |
|
297 |
|
Day 737 |
357 |
12.5 |
|
287 |
|
Day 737 |
359 |
12.5 |
|
282.2 |
|
Day 737 |
362 |
12.5 |
|
279.2 |
|
Day 737 |
367 |
12.5 |
|
271.6 |
|
Day 737 |
369 |
12.5 |
|
251.4 |
|
Day 737 |
372 |
12.5 |
|
251.4 |
|
Day 737 |
382 |
12.5 |
|
280.2 |
|
Day 737 |
395 |
12.5 |
|
224.2 |
|
Day 737 |
396 |
12.5 |
|
241.2 |
|
Day 737 |
397 |
12.5 |
|
257.8 |
|
Day 737 |
398 |
12.5 |
|
293.2 |
|
Day 737 |
401 |
12.5 |
|
290.2 |
|
Day 737 |
413 |
12.5 |
|
271 |
|
Day 737 |
415 |
12.5 |
|
269.4 |
|
Day 737 |
418 |
25 |
|
274.2 |
|
Day 737 |
419 |
25 |
|
285 |
|
Day 737 |
443 |
25 |
|
270 |
|
Day 737 |
447 |
25 |
|
266 |
|
Day 737 |
449 |
25 |
|
259.8 |
|
Day 737 |
459 |
25 |
|
292.4 |
|
Day 737 |
461 |
25 |
|
241.6 |
|
Day 737 |
464 |
25 |
|
277.2 |
|
Day 737 |
468 |
25 |
|
268.8 |
|
Day 737 |
488 |
50 |
|
265.2 |
|
Day 737 |
489 |
50 |
|
304.4 |
|
Day 737 |
504 |
50 |
|
395.2 |
|
Day 737 |
507 |
50 |
|
264.4 |
|
Day 737 |
534 |
50 |
|
268.8 |
|
Day 737 |
535 |
50 |
|
290.6 |
|
Abbreviations: |
NA: Not Available
|