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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | 1-trans-delta-9-Tetrahydrocannabinol |
CASRN: | ="1972-08-3" |
Study Number: | C56371B |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | GAVAGE |
TDMS Number: | 0521401 |
Sex: | Male |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (MG/KG) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 88 |
205 |
25 |
|
282.4 |
|
Day 113 |
77 |
0 |
|
393.7 |
|
Day 211 |
144 |
25 |
|
252.2 |
|
Day 221 |
215 |
50 |
|
235.2 |
|
Day 282 |
81 |
12.5 |
|
311.6 |
|
Day 289 |
202 |
25 |
|
298.6 |
|
Day 301 |
243 |
50 |
|
317.6 |
|
Day 324 |
185 |
25 |
|
300.4 |
|
Day 325 |
194 |
25 |
|
245.6 |
|
Day 368 |
134 |
12.5 |
|
310.2 |
|
Day 369 |
259 |
50 |
|
299 |
|
Day 378 |
183 |
25 |
|
247.8 |
|
Day 396 |
266 |
50 |
|
331.6 |
|
Day 438 |
13 |
0 |
|
272.2 |
|
Day 448 |
36 |
0 |
|
425 |
|
Day 448 |
67 |
0 |
|
461.2 |
|
Day 448 |
111 |
12.5 |
|
337.4 |
|
Day 448 |
96 |
12.5 |
|
396 |
|
Day 448 |
154 |
25 |
|
397.2 |
|
Day 448 |
163 |
25 |
|
284 |
|
Day 448 |
219 |
50 |
|
299.2 |
|
Day 448 |
247 |
50 |
|
323.4 |
|
Day 449 |
10 |
0 |
|
418.6 |
|
Day 449 |
69 |
0 |
|
456.4 |
|
Day 449 |
103 |
12.5 |
|
356.4 |
|
Day 449 |
133 |
12.5 |
|
349.2 |
|
Day 449 |
175 |
25 |
|
322 |
|
Day 449 |
180 |
25 |
|
321.2 |
|
Day 449 |
261 |
50 |
|
401.8 |
|
Day 449 |
268 |
50 |
|
337.6 |
|
Day 450 |
21 |
0 |
|
442.4 |
|
Day 450 |
79 |
0 |
|
448.2 |
|
Day 450 |
123 |
12.5 |
|
369.2 |
|
Day 450 |
135 |
12.5 |
|
372.2 |
|
Day 450 |
98 |
12.5 |
|
334.6 |
|
Day 450 |
193 |
25 |
|
311.2 |
|
Day 450 |
195 |
25 |
|
305.4 |
|
Day 450 |
208 |
25 |
|
298.8 |
|
Day 450 |
241 |
50 |
|
317.6 |
|
Day 450 |
267 |
50 |
|
353 |
|
Day 451 |
15 |
0 |
|
393.4 |
|
Day 451 |
4 |
0 |
|
431.2 |
|
Day 451 |
122 |
12.5 |
|
355.6 |
|
Day 451 |
164 |
25 |
|
330.2 |
|
Day 451 |
169 |
25 |
|
303 |
|
Day 451 |
227 |
50 |
|
327.8 |
|
Day 451 |
273 |
50 |
|
356 |
|
Day 452 |
11 |
0 |
|
433.8 |
|
Day 452 |
54 |
0 |
|
411.8 |
|
Day 452 |
120 |
12.5 |
|
358.8 |
|
Day 452 |
147 |
25 |
|
370 |
|
Day 452 |
212 |
50 |
|
382.4 |
|
Day 456 |
1 |
0 |
|
|
|
Day 456 |
16 |
0 |
|
|
|
Day 456 |
19 |
0 |
|
|
|
Day 456 |
20 |
0 |
|
|
|
Day 456 |
24 |
0 |
|
|
|
Day 456 |
29 |
0 |
|
|
|
Day 456 |
3 |
0 |
|
|
|
Day 456 |
34 |
0 |
|
|
|
Day 456 |
40 |
0 |
|
|
|
Day 456 |
41 |
0 |
|
|
|
Day 456 |
48 |
0 |
|
|
|
Day 456 |
59 |
0 |
|
|
|
Day 456 |
61 |
0 |
|
|
|
Day 456 |
70 |
0 |
|
|
|
Day 456 |
72 |
0 |
|
|
|
Day 456 |
78 |
0 |
|
|
|
Day 456 |
80 |
0 |
|
|
|
Day 456 |
9 |
0 |
|
|
|
Day 456 |
106 |
12.5 |
|
373.2 |
|
Day 456 |
153 |
25 |
|
|
|
Day 456 |
156 |
25 |
|
|
|
Day 456 |
166 |
25 |
|
|
|
Day 456 |
168 |
25 |
|
|
|
Day 456 |
176 |
25 |
|
|
|
Day 456 |
184 |
25 |
|
|
|
Day 456 |
187 |
25 |
|
|
|
Day 456 |
188 |
25 |
|
|
|
Day 456 |
206 |
25 |
|
|
|
Day 456 |
211 |
50 |
|
|
|
Day 456 |
216 |
50 |
|
|
|
Day 456 |
217 |
50 |
|
|
|
Day 456 |
223 |
50 |
|
|
|
Day 456 |
234 |
50 |
|
|
|
Day 456 |
235 |
50 |
|
|
|
Day 456 |
240 |
50 |
|
|
|
Day 456 |
256 |
50 |
|
|
|
Day 456 |
278 |
50 |
|
|
|
Day 499 |
60 |
0 |
|
435.2 |
|
Day 500 |
12 |
0 |
|
403.8 |
|
Day 505 |
35 |
0 |
|
433.2 |
|
Day 508 |
74 |
0 |
|
304.8 |
|
Day 515 |
252 |
50 |
|
396.2 |
|
Day 516 |
58 |
0 |
|
489.8 |
|
Day 524 |
47 |
0 |
|
465.8 |
|
Day 527 |
102 |
12.5 |
|
300.4 |
|
Day 531 |
238 |
50 |
|
324.4 |
|
Day 540 |
57 |
0 |
|
333.8 |
|
Day 556 |
56 |
0 |
|
394.6 |
|
Day 563 |
245 |
50 |
|
278 |
|
Day 566 |
17 |
0 |
|
409.4 |
|
Day 578 |
237 |
50 |
|
323.8 |
|
Day 585 |
23 |
0 |
|
344.4 |
|
Day 589 |
258 |
50 |
|
386.8 |
|
Day 592 |
209 |
25 |
|
298.6 |
|
Day 592 |
232 |
50 |
|
333.4 |
|
Day 595 |
178 |
25 |
|
315 |
|
Day 600 |
5 |
0 |
|
298 |
|
Day 600 |
100 |
12.5 |
|
231 |
|
Day 610 |
124 |
12.5 |
|
374.4 |
|
Day 610 |
230 |
50 |
|
413.6 |
|
Day 611 |
221 |
50 |
|
337.6 |
|
Day 616 |
14 |
0 |
|
280.2 |
|
Day 616 |
2 |
0 |
|
360.4 |
|
Day 617 |
45 |
0 |
|
314.6 |
|
Day 627 |
31 |
0 |
|
349.2 |
|
Day 627 |
129 |
12.5 |
|
264.2 |
|
Day 637 |
28 |
0 |
|
462.7 |
|
Day 637 |
131 |
12.5 |
|
263.8 |
|
Day 640 |
190 |
25 |
|
352.7 |
|
Day 643 |
139 |
12.5 |
|
337 |
|
Day 647 |
75 |
0 |
|
315 |
|
Day 650 |
167 |
25 |
|
263.4 |
|
Day 651 |
189 |
25 |
|
253.6 |
|
Day 653 |
186 |
25 |
|
309.2 |
|
Day 659 |
6 |
0 |
|
376.4 |
|
Day 659 |
161 |
25 |
|
338.2 |
|
Day 659 |
263 |
50 |
|
384.8 |
|
Day 662 |
64 |
0 |
|
329.6 |
|
Day 662 |
107 |
12.5 |
|
267.4 |
|
Day 662 |
264 |
50 |
|
291.4 |
|
Day 668 |
157 |
25 |
|
337.2 |
|
Day 668 |
272 |
50 |
|
296.4 |
|
Day 671 |
38 |
0 |
|
413.4 |
|
Day 674 |
125 |
12.5 |
|
325 |
|
Day 674 |
177 |
25 |
|
282 |
|
Day 675 |
101 |
12.5 |
|
502 |
|
Day 676 |
117 |
12.5 |
|
301.6 |
|
Day 678 |
50 |
0 |
|
336 |
|
Day 679 |
121 |
12.5 |
|
328.2 |
|
Day 683 |
22 |
0 |
|
341.4 |
|
Day 683 |
63 |
0 |
|
301.4 |
|
Day 684 |
265 |
50 |
|
302.2 |
|
Day 686 |
140 |
12.5 |
|
277.8 |
|
Day 687 |
224 |
50 |
|
358.4 |
|
Day 688 |
231 |
50 |
|
333.2 |
|
Day 690 |
138 |
12.5 |
|
275.8 |
|
Day 690 |
226 |
50 |
|
292 |
|
Day 697 |
271 |
50 |
|
257 |
|
Day 709 |
71 |
0 |
|
351.2 |
|
Day 709 |
148 |
25 |
|
293.4 |
|
Day 709 |
155 |
25 |
|
338.6 |
|
Day 709 |
162 |
25 |
|
344.2 |
|
Day 710 |
270 |
50 |
|
337.6 |
|
Day 715 |
76 |
0 |
|
396.4 |
|
Day 717 |
46 |
0 |
|
257.6 |
|
Day 718 |
39 |
0 |
|
364.2 |
|
Day 721 |
7 |
0 |
|
287.4 |
|
Day 725 |
108 |
12.5 |
|
366.6 |
|
Day 725 |
113 |
12.5 |
|
342.4 |
|
Day 725 |
118 |
12.5 |
|
406.2 |
|
Day 725 |
119 |
12.5 |
|
362.8 |
|
Day 725 |
127 |
12.5 |
|
361.2 |
|
Day 725 |
130 |
12.5 |
|
352.6 |
|
Day 725 |
132 |
12.5 |
|
352.4 |
|
Day 725 |
136 |
12.5 |
|
327.8 |
|
Day 725 |
85 |
12.5 |
|
382.2 |
|
Day 725 |
88 |
12.5 |
|
356 |
|
Day 725 |
90 |
12.5 |
|
356.2 |
|
Day 725 |
91 |
12.5 |
|
362.2 |
|
Day 725 |
93 |
12.5 |
|
367.2 |
|
Day 725 |
94 |
12.5 |
|
291.4 |
|
Day 725 |
97 |
12.5 |
|
399.8 |
|
Day 725 |
142 |
25 |
|
348.8 |
|
Day 725 |
143 |
25 |
|
393.2 |
|
Day 725 |
146 |
25 |
|
404 |
|
Day 725 |
150 |
25 |
|
308.6 |
|
Day 725 |
165 |
25 |
|
361 |
|
Day 725 |
174 |
25 |
|
317 |
|
Day 725 |
179 |
25 |
|
317.2 |
|
Day 725 |
181 |
25 |
|
418.9 |
|
Day 725 |
191 |
25 |
|
344.4 |
|
Day 725 |
196 |
25 |
|
358.6 |
|
Day 725 |
197 |
25 |
|
377 |
|
Day 725 |
198 |
25 |
|
329 |
|
Day 725 |
200 |
25 |
|
420.8 |
|
Day 725 |
204 |
25 |
|
355.8 |
|
Day 725 |
210 |
25 |
|
369.6 |
|
Day 725 |
214 |
50 |
|
355.2 |
|
Day 725 |
220 |
50 |
|
381.8 |
|
Day 725 |
228 |
50 |
|
361 |
|
Day 725 |
233 |
50 |
|
364.8 |
|
Day 725 |
242 |
50 |
|
379.4 |
|
Day 725 |
246 |
50 |
|
318 |
|
Day 725 |
248 |
50 |
|
329 |
|
Day 725 |
250 |
50 |
|
374 |
|
Day 725 |
251 |
50 |
|
356 |
|
Day 725 |
260 |
50 |
|
382.4 |
|
Day 725 |
269 |
50 |
|
404 |
|
Day 725 |
274 |
50 |
|
380.8 |
|
Day 725 |
275 |
50 |
|
363.6 |
|
Day 725 |
277 |
50 |
|
354 |
|
Day 725 |
279 |
50 |
|
330.4 |
|
Day 726 |
110 |
12.5 |
|
385.8 |
|
Day 726 |
128 |
12.5 |
|
357.6 |
|
Day 726 |
92 |
12.5 |
|
366.6 |
|
Day 726 |
141 |
25 |
|
358.8 |
|
Day 726 |
160 |
25 |
|
364.4 |
|
Day 726 |
207 |
25 |
|
351.8 |
|
Day 726 |
239 |
50 |
|
371 |
|
Day 726 |
254 |
50 |
|
371.2 |
|
Day 726 |
276 |
50 |
|
418.8 |
|
Day 727 |
114 |
12.5 |
|
346.6 |
|
Day 727 |
126 |
12.5 |
|
378.4 |
|
Day 727 |
87 |
12.5 |
|
404.2 |
|
Day 727 |
145 |
25 |
|
363.6 |
|
Day 727 |
151 |
25 |
|
405.4 |
|
Day 727 |
152 |
25 |
|
354.6 |
|
Day 727 |
225 |
50 |
|
367.4 |
|
Day 727 |
244 |
50 |
|
348 |
|
Day 727 |
280 |
50 |
|
368.6 |
|
Day 728 |
109 |
12.5 |
|
323.8 |
|
Day 728 |
112 |
12.5 |
|
441.6 |
|
Day 728 |
84 |
12.5 |
|
346 |
|
Day 728 |
170 |
25 |
|
373.2 |
|
Day 728 |
192 |
25 |
|
372.4 |
|
Day 728 |
199 |
25 |
|
364.6 |
|
Day 728 |
218 |
50 |
|
357.6 |
|
Day 728 |
249 |
50 |
|
354.6 |
|
Day 728 |
257 |
50 |
|
389.2 |
|
Day 730 |
104 |
12.5 |
|
367 |
|
Day 730 |
105 |
12.5 |
|
353.2 |
|
Day 730 |
115 |
12.5 |
|
338.2 |
|
Day 730 |
116 |
12.5 |
|
385.8 |
|
Day 730 |
137 |
12.5 |
|
343.2 |
|
Day 730 |
82 |
12.5 |
|
345.4 |
|
Day 730 |
83 |
12.5 |
|
380.8 |
|
Day 730 |
86 |
12.5 |
|
356.6 |
|
Day 730 |
89 |
12.5 |
|
361.4 |
|
Day 730 |
95 |
12.5 |
|
342 |
|
Day 730 |
99 |
12.5 |
|
365.4 |
|
Day 730 |
149 |
25 |
|
349.4 |
|
Day 730 |
158 |
25 |
|
363.2 |
|
Day 730 |
159 |
25 |
|
351.8 |
|
Day 730 |
171 |
25 |
|
393.8 |
|
Day 730 |
172 |
25 |
|
331.2 |
|
Day 730 |
173 |
25 |
|
380 |
|
Day 730 |
182 |
25 |
|
367 |
|
Day 730 |
201 |
25 |
|
368.6 |
|
Day 730 |
203 |
25 |
|
356 |
|
Day 730 |
213 |
50 |
|
357.4 |
|
Day 730 |
222 |
50 |
|
361.8 |
|
Day 730 |
229 |
50 |
|
368.8 |
|
Day 730 |
236 |
50 |
|
336.2 |
|
Day 730 |
253 |
50 |
|
362.4 |
|
Day 730 |
255 |
50 |
|
379.2 |
|
Day 731 |
18 |
0 |
|
368.6 |
|
Day 731 |
25 |
0 |
|
418.6 |
|
Day 731 |
26 |
0 |
|
416.2 |
|
Day 731 |
27 |
0 |
|
405.4 |
|
Day 731 |
30 |
0 |
|
367 |
|
Day 731 |
32 |
0 |
|
411 |
|
Day 731 |
33 |
0 |
|
435.4 |
|
Day 731 |
37 |
0 |
|
375 |
|
Day 731 |
42 |
0 |
|
412.4 |
|
Day 731 |
43 |
0 |
|
441.8 |
|
Day 731 |
44 |
0 |
|
421.6 |
|
Day 731 |
49 |
0 |
|
435 |
|
Day 731 |
51 |
0 |
|
372.8 |
|
Day 731 |
52 |
0 |
|
334.6 |
|
Day 731 |
53 |
0 |
|
448.2 |
|
Day 731 |
55 |
0 |
|
317.6 |
|
Day 731 |
62 |
0 |
|
400.8 |
|
Day 731 |
65 |
0 |
|
412.8 |
|
Day 731 |
66 |
0 |
|
424 |
|
Day 731 |
68 |
0 |
|
424.2 |
|
Day 731 |
73 |
0 |
|
392 |
|
Day 731 |
8 |
0 |
|
391.6 |
|
Day 731 |
262 |
50 |
|
367.6 |
|
Abbreviations: |
NA: Not Available
|