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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | 1-trans-delta-9-Tetrahydrocannabinol |
CASRN: | ="1972-08-3" |
Study Number: | C56371B |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | GAVAGE |
TDMS Number: | 0521402 |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (MG/KG) |
Control Code |
Final Body Weight |
Final Body Weight (g) |
Day 6 |
216 |
500 |
|
18.8 |
|
Day 28 |
191 |
250 |
|
23.4 |
|
Day 85 |
248 |
500 |
|
28.8 |
|
Day 86 |
222 |
500 |
|
19.4 |
|
Day 90 |
249 |
500 |
|
26.6 |
|
Day 94 |
149 |
250 |
|
25 |
|
Day 146 |
14 |
0 |
|
27.6 |
|
Day 191 |
267 |
500 |
|
32.2 |
|
Day 206 |
238 |
500 |
|
31.8 |
|
Day 225 |
145 |
250 |
|
37.2 |
|
Day 246 |
158 |
250 |
|
33.6 |
|
Day 251 |
221 |
500 |
|
32.8 |
|
Day 256 |
253 |
500 |
|
19.8 |
|
Day 267 |
251 |
500 |
|
35 |
|
Day 275 |
230 |
500 |
|
25.8 |
|
Day 395 |
153 |
250 |
|
38.4 |
|
Day 405 |
144 |
250 |
|
33.2 |
|
Day 418 |
213 |
500 |
|
29.8 |
|
Day 444 |
257 |
500 |
|
38.2 |
|
Day 450 |
194 |
250 |
|
40.6 |
|
Day 454 |
271 |
500 |
|
29.4 |
|
Day 454 |
279 |
500 |
|
38 |
|
Day 456 |
234 |
500 |
|
37.8 |
|
Day 461 |
10 |
0 |
|
|
|
Day 461 |
30 |
0 |
|
|
|
Day 461 |
36 |
0 |
|
|
|
Day 461 |
42 |
0 |
|
|
|
Day 461 |
44 |
0 |
|
|
|
Day 461 |
49 |
0 |
|
|
|
Day 461 |
53 |
0 |
|
|
|
Day 461 |
54 |
0 |
|
|
|
Day 461 |
60 |
0 |
|
|
|
Day 461 |
62 |
0 |
|
|
|
Day 461 |
155 |
250 |
|
|
|
Day 461 |
171 |
250 |
|
|
|
Day 461 |
172 |
250 |
|
|
|
Day 461 |
178 |
250 |
|
|
|
Day 461 |
183 |
250 |
|
|
|
Day 461 |
189 |
250 |
|
|
|
Day 461 |
199 |
250 |
|
|
|
Day 461 |
207 |
250 |
|
|
|
Day 461 |
208 |
250 |
|
|
|
Day 461 |
217 |
500 |
|
|
|
Day 461 |
224 |
500 |
|
|
|
Day 461 |
229 |
500 |
|
|
|
Day 461 |
233 |
500 |
|
|
|
Day 461 |
245 |
500 |
|
|
|
Day 461 |
262 |
500 |
|
|
|
Day 461 |
263 |
500 |
|
|
|
Day 461 |
264 |
500 |
|
|
|
Day 461 |
272 |
500 |
|
|
|
Day 461 |
275 |
500 |
|
|
|
Day 463 |
18 |
0 |
|
|
|
Day 463 |
32 |
0 |
|
|
|
Day 463 |
45 |
0 |
|
|
|
Day 463 |
51 |
0 |
|
|
|
Day 463 |
73 |
0 |
|
|
|
Day 463 |
74 |
0 |
|
|
|
Day 463 |
76 |
0 |
|
|
|
Day 463 |
9 |
0 |
|
|
|
Day 468 |
276 |
500 |
|
34.4 |
|
Day 486 |
179 |
250 |
|
36 |
|
Day 493 |
167 |
250 |
|
35.6 |
|
Day 503 |
244 |
500 |
|
31.4 |
|
Day 508 |
197 |
250 |
|
35.6 |
|
Day 538 |
69 |
0 |
|
32.8 |
|
Day 554 |
24 |
0 |
|
43.4 |
|
Day 554 |
254 |
500 |
|
38 |
|
Day 561 |
242 |
500 |
|
34.4 |
|
Day 563 |
132 |
125 |
|
32 |
|
Day 563 |
196 |
250 |
|
26.6 |
|
Day 563 |
266 |
500 |
|
41 |
|
Day 566 |
96 |
125 |
|
27.2 |
|
Day 574 |
195 |
250 |
|
22.8 |
|
Day 585 |
46 |
0 |
|
43.6 |
|
Day 587 |
225 |
500 |
|
36.8 |
|
Day 591 |
35 |
0 |
|
45.6 |
|
Day 591 |
87 |
125 |
|
40.2 |
|
Day 598 |
100 |
125 |
|
24.8 |
|
Day 599 |
269 |
500 |
|
38.8 |
|
Day 600 |
246 |
500 |
|
35.8 |
|
Day 611 |
161 |
250 |
|
34 |
|
Day 611 |
236 |
500 |
|
42.8 |
|
Day 625 |
227 |
500 |
|
21.2 |
|
Day 629 |
274 |
500 |
|
37.8 |
|
Day 638 |
112 |
125 |
|
45 |
|
Day 670 |
147 |
250 |
|
42.8 |
|
Day 672 |
20 |
0 |
|
34.8 |
|
Day 672 |
65 |
0 |
|
46.2 |
|
Day 678 |
41 |
0 |
|
27.4 |
|
Day 678 |
8 |
0 |
|
32.8 |
|
Day 705 |
12 |
0 |
|
29.2 |
|
Day 707 |
66 |
0 |
|
46.6 |
|
Day 709 |
135 |
125 |
|
31.6 |
|
Day 716 |
141 |
250 |
|
24.6 |
|
Day 723 |
25 |
0 |
|
20.2 |
|
Day 725 |
89 |
125 |
|
41 |
|
Day 728 |
160 |
250 |
|
32 |
|
Day 730 |
11 |
0 |
|
39.8 |
|
Day 730 |
17 |
0 |
|
53 |
|
Day 730 |
21 |
0 |
|
56 |
|
Day 730 |
26 |
0 |
|
48.6 |
|
Day 730 |
27 |
0 |
|
50 |
|
Day 730 |
33 |
0 |
|
41 |
|
Day 730 |
34 |
0 |
|
45.8 |
|
Day 730 |
43 |
0 |
|
55.8 |
|
Day 730 |
47 |
0 |
|
55.2 |
|
Day 730 |
50 |
0 |
|
56 |
|
Day 730 |
57 |
0 |
|
50.4 |
|
Day 730 |
7 |
0 |
|
53.6 |
|
Day 730 |
77 |
0 |
|
36.4 |
|
Day 730 |
109 |
125 |
|
33.4 |
|
Day 730 |
111 |
125 |
|
44 |
|
Day 730 |
115 |
125 |
|
43.8 |
|
Day 730 |
124 |
125 |
|
38.8 |
|
Day 730 |
81 |
125 |
|
30.8 |
|
Day 730 |
84 |
125 |
|
37.8 |
|
Day 730 |
88 |
125 |
|
50.2 |
|
Day 730 |
91 |
125 |
|
47.6 |
|
Day 730 |
97 |
125 |
|
47.2 |
|
Day 730 |
146 |
250 |
|
41.6 |
|
Day 730 |
152 |
250 |
|
37.6 |
|
Day 730 |
156 |
250 |
|
38.4 |
|
Day 730 |
164 |
250 |
|
33.2 |
|
Day 730 |
169 |
250 |
|
45 |
|
Day 730 |
175 |
250 |
|
44.8 |
|
Day 730 |
177 |
250 |
|
33.4 |
|
Day 730 |
180 |
250 |
|
41 |
|
Day 730 |
188 |
250 |
|
40.2 |
|
Day 730 |
201 |
250 |
|
36.6 |
|
Day 730 |
203 |
250 |
|
41.8 |
|
Day 730 |
209 |
250 |
|
41 |
|
Day 730 |
219 |
500 |
|
34.4 |
|
Day 730 |
243 |
500 |
|
34.4 |
|
Day 730 |
247 |
500 |
|
35.6 |
|
Day 730 |
258 |
500 |
|
37.4 |
|
Day 730 |
261 |
500 |
|
34.2 |
|
Day 730 |
277 |
500 |
|
37.8 |
|
Day 730 |
278 |
500 |
|
29.4 |
|
Day 731 |
15 |
0 |
|
51 |
|
Day 731 |
29 |
0 |
|
25 |
|
Day 731 |
31 |
0 |
|
29.8 |
|
Day 731 |
38 |
0 |
|
49.6 |
|
Day 731 |
39 |
0 |
|
47.6 |
|
Day 731 |
48 |
0 |
|
56.2 |
|
Day 731 |
52 |
0 |
|
38 |
|
Day 731 |
68 |
0 |
|
50.6 |
|
Day 731 |
79 |
0 |
|
49.4 |
|
Day 731 |
103 |
125 |
|
37.4 |
|
Day 731 |
104 |
125 |
|
27.6 |
|
Day 731 |
108 |
125 |
|
41.6 |
|
Day 731 |
116 |
125 |
|
38.4 |
|
Day 731 |
117 |
125 |
|
47.8 |
|
Day 731 |
119 |
125 |
|
43 |
|
Day 731 |
120 |
125 |
|
44 |
|
Day 731 |
121 |
125 |
|
43.2 |
|
Day 731 |
123 |
125 |
|
51.2 |
|
Day 731 |
127 |
125 |
|
52.2 |
|
Day 731 |
129 |
125 |
|
42.8 |
|
Day 731 |
130 |
125 |
|
42.4 |
|
Day 731 |
133 |
125 |
|
45.6 |
|
Day 731 |
139 |
125 |
|
45.4 |
|
Day 731 |
82 |
125 |
|
44.2 |
|
Day 731 |
98 |
125 |
|
40.2 |
|
Day 731 |
143 |
250 |
|
37 |
|
Day 731 |
157 |
250 |
|
41.2 |
|
Day 731 |
159 |
250 |
|
36.4 |
|
Day 731 |
162 |
250 |
|
37.6 |
|
Day 731 |
163 |
250 |
|
38.2 |
|
Day 731 |
165 |
250 |
|
32 |
|
Day 731 |
173 |
250 |
|
34.8 |
|
Day 731 |
176 |
250 |
|
37.6 |
|
Day 731 |
181 |
250 |
|
43.8 |
|
Day 731 |
187 |
250 |
|
36.8 |
|
Day 731 |
210 |
250 |
|
40 |
|
Day 731 |
214 |
500 |
|
33.6 |
|
Day 731 |
237 |
500 |
|
33.6 |
|
Day 731 |
259 |
500 |
|
36.4 |
|
Day 734 |
1 |
0 |
|
51.4 |
|
Day 734 |
13 |
0 |
|
51.4 |
|
Day 734 |
3 |
0 |
|
54.2 |
|
Day 734 |
40 |
0 |
|
47.6 |
|
Day 734 |
56 |
0 |
|
38.2 |
|
Day 734 |
58 |
0 |
|
36 |
|
Day 734 |
6 |
0 |
|
45.6 |
|
Day 734 |
61 |
0 |
|
53.4 |
|
Day 734 |
64 |
0 |
|
47.4 |
|
Day 734 |
78 |
0 |
|
48.2 |
|
Day 734 |
105 |
125 |
|
45.8 |
|
Day 734 |
107 |
125 |
|
37 |
|
Day 734 |
110 |
125 |
|
42.2 |
|
Day 734 |
118 |
125 |
|
34.4 |
|
Day 734 |
126 |
125 |
|
49 |
|
Day 734 |
138 |
125 |
|
43.6 |
|
Day 734 |
85 |
125 |
|
37.8 |
|
Day 734 |
90 |
125 |
|
42.4 |
|
Day 734 |
94 |
125 |
|
36.2 |
|
Day 734 |
142 |
250 |
|
35.6 |
|
Day 734 |
166 |
250 |
|
30 |
|
Day 734 |
170 |
250 |
|
36.8 |
|
Day 734 |
186 |
250 |
|
34.8 |
|
Day 734 |
193 |
250 |
|
39 |
|
Day 734 |
200 |
250 |
|
42.4 |
|
Day 734 |
204 |
250 |
|
39.2 |
|
Day 734 |
205 |
250 |
|
36.4 |
|
Day 734 |
212 |
500 |
|
35 |
|
Day 734 |
215 |
500 |
|
38.8 |
|
Day 734 |
220 |
500 |
|
31.4 |
|
Day 734 |
223 |
500 |
|
34.4 |
|
Day 734 |
226 |
500 |
|
37.6 |
|
Day 734 |
235 |
500 |
|
37.2 |
|
Day 734 |
240 |
500 |
|
40.4 |
|
Day 734 |
241 |
500 |
|
33 |
|
Day 734 |
255 |
500 |
|
30 |
|
Day 734 |
260 |
500 |
|
34.4 |
|
Day 734 |
265 |
500 |
|
38.4 |
|
Day 734 |
268 |
500 |
|
33 |
|
Day 734 |
280 |
500 |
|
35 |
|
Day 735 |
16 |
0 |
|
44 |
|
Day 735 |
2 |
0 |
|
48.8 |
|
Day 735 |
22 |
0 |
|
52.6 |
|
Day 735 |
28 |
0 |
|
46.8 |
|
Day 735 |
37 |
0 |
|
48.8 |
|
Day 735 |
4 |
0 |
|
52.8 |
|
Day 735 |
5 |
0 |
|
52.4 |
|
Day 735 |
59 |
0 |
|
51.2 |
|
Day 735 |
71 |
0 |
|
51.8 |
|
Day 735 |
101 |
125 |
|
40 |
|
Day 735 |
106 |
125 |
|
38.6 |
|
Day 735 |
125 |
125 |
|
42.4 |
|
Day 735 |
128 |
125 |
|
39 |
|
Day 735 |
131 |
125 |
|
43.2 |
|
Day 735 |
137 |
125 |
|
45.8 |
|
Day 735 |
83 |
125 |
|
41.8 |
|
Day 735 |
92 |
125 |
|
44 |
|
Day 735 |
95 |
125 |
|
44.4 |
|
Day 735 |
150 |
250 |
|
36 |
|
Day 735 |
168 |
250 |
|
32.2 |
|
Day 735 |
174 |
250 |
|
35.6 |
|
Day 735 |
184 |
250 |
|
40.8 |
|
Day 735 |
198 |
250 |
|
42 |
|
Day 735 |
206 |
250 |
|
33 |
|
Day 735 |
218 |
500 |
|
35.2 |
|
Day 735 |
231 |
500 |
|
34.8 |
|
Day 735 |
232 |
500 |
|
36.4 |
|
Day 735 |
252 |
500 |
|
35.2 |
|
Day 735 |
270 |
500 |
|
33.2 |
|
Day 736 |
19 |
0 |
|
58.2 |
|
Day 736 |
23 |
0 |
|
35.4 |
|
Day 736 |
55 |
0 |
|
48.2 |
|
Day 736 |
63 |
0 |
|
34 |
|
Day 736 |
67 |
0 |
|
30 |
|
Day 736 |
70 |
0 |
|
32.4 |
|
Day 736 |
72 |
0 |
|
47 |
|
Day 736 |
75 |
0 |
|
45.8 |
|
Day 736 |
80 |
0 |
|
48 |
|
Day 736 |
102 |
125 |
|
42.8 |
|
Day 736 |
113 |
125 |
|
41.4 |
|
Day 736 |
114 |
125 |
|
34 |
|
Day 736 |
122 |
125 |
|
53.8 |
|
Day 736 |
134 |
125 |
|
39.4 |
|
Day 736 |
136 |
125 |
|
40.4 |
|
Day 736 |
140 |
125 |
|
43 |
|
Day 736 |
86 |
125 |
|
46.6 |
|
Day 736 |
93 |
125 |
|
34.4 |
|
Day 736 |
99 |
125 |
|
44.4 |
|
Day 736 |
148 |
250 |
|
36.6 |
|
Day 736 |
151 |
250 |
|
36.8 |
|
Day 736 |
154 |
250 |
|
34.8 |
|
Day 736 |
182 |
250 |
|
35.4 |
|
Day 736 |
185 |
250 |
|
34 |
|
Day 736 |
190 |
250 |
|
37.4 |
|
Day 736 |
192 |
250 |
|
32.6 |
|
Day 736 |
202 |
250 |
|
33.4 |
|
Day 736 |
211 |
500 |
|
33.2 |
|
Day 736 |
228 |
500 |
|
30.6 |
|
Day 736 |
239 |
500 |
|
34.2 |
|
Day 736 |
250 |
500 |
|
35 |
|
Day 736 |
256 |
500 |
|
28.6 |
|
Day 736 |
273 |
500 |
|
37 |
|
Abbreviations: |
NA: Not Available
|