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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | 3,3'-Dimethylbenzidine dihydrochloride |
CASRN: | ="612-82-8" |
Study Number: | C99990 |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | DOSED WATER |
TDMS Number: | 0516601 |
Sex: | Female |
Strain and Species: | F 344/N Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group () |
Control Code |
Final Body Weight (g) |
Day 142 |
344 |
0.007 |
|
218 |
Day 142 |
464 |
0.015 |
|
191.1 |
Day 184 |
323 |
0.007 |
|
199.9 |
Day 229 |
351 |
0.007 |
|
221.8 |
Day 229 |
462 |
0.015 |
|
199.6 |
Day 247 |
507 |
0.015 |
|
163.5 |
Day 251 |
508 |
0.015 |
|
214.9 |
Day 254 |
456 |
0.015 |
|
159.7 |
Day 264 |
473 |
0.015 |
|
199.1 |
Day 264 |
496 |
0.015 |
|
199.2 |
Day 265 |
470 |
0.015 |
|
193.4 |
Day 268 |
371 |
0.007 |
|
226.2 |
Day 275 |
71 |
0 |
|
214.1 |
Day 275 |
72 |
0 |
|
218.2 |
Day 275 |
73 |
0 |
|
242.2 |
Day 275 |
74 |
0 |
|
229.8 |
Day 275 |
75 |
0 |
|
253.5 |
Day 275 |
76 |
0 |
|
232 |
Day 275 |
77 |
0 |
|
249.9 |
Day 275 |
78 |
0 |
|
249 |
Day 275 |
79 |
0 |
|
222.3 |
Day 275 |
80 |
0 |
|
265.4 |
Day 275 |
451 |
0.015 |
|
203.6 |
Day 275 |
452 |
0.015 |
|
186.8 |
Day 275 |
453 |
0.015 |
|
215.9 |
Day 275 |
454 |
0.015 |
|
203.2 |
Day 275 |
455 |
0.015 |
|
203.3 |
Day 275 |
457 |
0.015 |
|
189.2 |
Day 275 |
458 |
0.015 |
|
196.6 |
Day 275 |
459 |
0.015 |
|
193 |
Day 275 |
460 |
0.015 |
|
189.4 |
Day 275 |
461 |
0.015 |
|
190.5 |
Day 280 |
466 |
0.015 |
|
220.8 |
Day 285 |
504 |
0.015 |
|
200.4 |
Day 285 |
505 |
0.015 |
|
191.8 |
Day 295 |
494 |
0.015 |
|
115.5 |
Day 296 |
479 |
0.015 |
|
215.2 |
Day 296 |
490 |
0.015 |
|
211.1 |
Day 309 |
339 |
0.007 |
|
185 |
Day 310 |
341 |
0.007 |
|
189.1 |
Day 315 |
306 |
0.007 |
|
237.4 |
Day 315 |
337 |
0.007 |
|
225.6 |
Day 315 |
338 |
0.007 |
|
126.8 |
Day 315 |
482 |
0.015 |
|
164.1 |
Day 315 |
485 |
0.015 |
|
207.6 |
Day 320 |
379 |
0.007 |
|
134.1 |
Day 327 |
357 |
0.007 |
|
130.2 |
Day 335 |
506 |
0.015 |
|
172.9 |
Day 335 |
514 |
0.015 |
|
161.2 |
Day 336 |
480 |
0.015 |
|
209.7 |
Day 338 |
307 |
0.007 |
|
249.4 |
Day 338 |
311 |
0.007 |
|
241.5 |
Day 338 |
356 |
0.007 |
|
149.9 |
Day 338 |
365 |
0.007 |
|
212.6 |
Day 338 |
376 |
0.007 |
|
174.4 |
Day 338 |
469 |
0.015 |
|
227.5 |
Day 338 |
478 |
0.015 |
|
181.5 |
Day 338 |
489 |
0.015 |
|
171.5 |
Day 341 |
467 |
0.015 |
|
167.8 |
Day 341 |
477 |
0.015 |
|
134.1 |
Day 343 |
471 |
0.015 |
|
207 |
Day 343 |
475 |
0.015 |
|
147.6 |
Day 343 |
513 |
0.015 |
|
230.9 |
Day 355 |
332 |
0.007 |
|
156.5 |
Day 355 |
463 |
0.015 |
|
175.3 |
Day 355 |
465 |
0.015 |
|
151 |
Day 357 |
194 |
0.003 |
|
285.1 |
Day 363 |
378 |
0.007 |
|
185.2 |
Day 364 |
331 |
0.007 |
|
184.5 |
Day 364 |
501 |
0.015 |
|
209.7 |
Day 365 |
358 |
0.007 |
|
196.2 |
Day 369 |
352 |
0.007 |
|
128.1 |
Day 369 |
353 |
0.007 |
|
134.3 |
Day 370 |
324 |
0.007 |
|
149.9 |
Day 370 |
499 |
0.015 |
|
165.1 |
Day 370 |
520 |
0.015 |
|
126.2 |
Day 377 |
486 |
0.015 |
|
165.4 |
Day 378 |
326 |
0.007 |
|
151 |
Day 378 |
498 |
0.015 |
|
143 |
Day 379 |
329 |
0.007 |
|
190.7 |
Day 383 |
367 |
0.007 |
|
175.4 |
Day 383 |
502 |
0.015 |
|
211.7 |
Day 383 |
511 |
0.015 |
|
166.1 |
Day 384 |
223 |
0.003 |
|
230.6 |
Day 384 |
345 |
0.007 |
|
207.7 |
Day 384 |
512 |
0.015 |
|
183.4 |
Day 384 |
516 |
0.015 |
|
147.7 |
Day 388 |
380 |
0.007 |
|
203.3 |
Day 390 |
100 |
0 |
|
200.4 |
Day 390 |
325 |
0.007 |
|
216.3 |
Day 390 |
362 |
0.007 |
|
217.6 |
Day 390 |
488 |
0.015 |
|
209.5 |
Day 391 |
196 |
0.003 |
|
275.5 |
Day 391 |
213 |
0.003 |
|
259.4 |
Day 391 |
220 |
0.003 |
|
222.5 |
Day 391 |
328 |
0.007 |
|
201.6 |
Day 391 |
347 |
0.007 |
|
233.6 |
Day 391 |
349 |
0.007 |
|
218.9 |
Day 391 |
476 |
0.015 |
|
233 |
Day 391 |
484 |
0.015 |
|
199.6 |
Day 391 |
503 |
0.015 |
|
214.9 |
Day 391 |
509 |
0.015 |
|
220.6 |
Day 391 |
517 |
0.015 |
|
204.4 |
Day 393 |
191 |
0.003 |
|
211.7 |
Day 405 |
316 |
0.007 |
|
204 |
Day 405 |
354 |
0.007 |
|
166.2 |
Day 405 |
363 |
0.007 |
|
199.3 |
Day 405 |
492 |
0.015 |
|
193 |
Day 405 |
518 |
0.015 |
|
225.7 |
Day 405 |
519 |
0.015 |
|
192.3 |
Day 406 |
318 |
0.007 |
|
226.5 |
Day 406 |
319 |
0.007 |
|
236.4 |
Day 406 |
322 |
0.007 |
|
227.8 |
Day 406 |
334 |
0.007 |
|
207.9 |
Day 406 |
336 |
0.007 |
|
239 |
Day 406 |
474 |
0.015 |
|
177.1 |
Day 406 |
495 |
0.015 |
|
219.2 |
Day 406 |
500 |
0.015 |
|
218.8 |
Day 409 |
350 |
0.007 |
|
165.6 |
Day 419 |
313 |
0.007 |
|
191.5 |
Day 421 |
81 |
0 |
|
278.4 |
Day 421 |
82 |
0 |
|
358.3 |
Day 421 |
83 |
0 |
|
286.9 |
Day 421 |
84 |
0 |
|
298.5 |
Day 421 |
85 |
0 |
|
301.3 |
Day 421 |
186 |
0.003 |
|
298.1 |
Day 421 |
187 |
0.003 |
|
268.5 |
Day 421 |
188 |
0.003 |
|
225.1 |
Day 421 |
189 |
0.003 |
|
312.2 |
Day 421 |
190 |
0.003 |
|
279.6 |
Day 421 |
308 |
0.007 |
|
257.1 |
Day 421 |
309 |
0.007 |
|
221.5 |
Day 421 |
310 |
0.007 |
|
201.4 |
Day 421 |
312 |
0.007 |
|
246.7 |
Day 421 |
314 |
0.007 |
|
238.9 |
Day 421 |
468 |
0.015 |
|
219.2 |
Day 421 |
472 |
0.015 |
|
217.1 |
Day 421 |
481 |
0.015 |
|
233.7 |
Day 421 |
483 |
0.015 |
|
219.3 |
Day 421 |
487 |
0.015 |
|
189.7 |
Day 422 |
101 |
0 |
|
248.9 |
Day 422 |
102 |
0 |
|
291.9 |
Day 422 |
103 |
0 |
|
301.2 |
Day 422 |
104 |
0 |
|
275.4 |
Day 422 |
105 |
0 |
|
301.9 |
Day 422 |
106 |
0 |
|
293.7 |
Day 422 |
107 |
0 |
|
277.3 |
Day 422 |
86 |
0 |
|
271.7 |
Day 422 |
87 |
0 |
|
258.7 |
Day 422 |
88 |
0 |
|
288.3 |
Day 422 |
89 |
0 |
|
344.5 |
Day 422 |
90 |
0 |
|
351.8 |
Day 422 |
91 |
0 |
|
328.8 |
Day 422 |
92 |
0 |
|
325.7 |
Day 422 |
93 |
0 |
|
283 |
Day 422 |
94 |
0 |
|
295.3 |
Day 422 |
95 |
0 |
|
290 |
Day 422 |
96 |
0 |
|
293.4 |
Day 422 |
97 |
0 |
|
377.6 |
Day 422 |
98 |
0 |
|
326.1 |
Day 422 |
99 |
0 |
|
292.8 |
Day 422 |
192 |
0.003 |
|
299.3 |
Day 422 |
193 |
0.003 |
|
271.5 |
Day 422 |
195 |
0.003 |
|
328.9 |
Day 422 |
197 |
0.003 |
|
268.8 |
Day 422 |
198 |
0.003 |
|
241.5 |
Day 422 |
199 |
0.003 |
|
288.1 |
Day 422 |
200 |
0.003 |
|
289.1 |
Day 422 |
201 |
0.003 |
|
270.6 |
Day 422 |
202 |
0.003 |
|
278.6 |
Day 422 |
203 |
0.003 |
|
300.8 |
Day 422 |
204 |
0.003 |
|
285.4 |
Day 422 |
205 |
0.003 |
|
338 |
Day 422 |
207 |
0.003 |
|
241.7 |
Day 422 |
208 |
0.003 |
|
286.9 |
Day 422 |
210 |
0.003 |
|
266.3 |
Day 422 |
211 |
0.003 |
|
296.9 |
Day 422 |
212 |
0.003 |
|
256.9 |
Day 422 |
214 |
0.003 |
|
284 |
Day 422 |
216 |
0.003 |
|
232.3 |
Day 422 |
217 |
0.003 |
|
266 |
Day 422 |
315 |
0.007 |
|
218.1 |
Day 422 |
317 |
0.007 |
|
233 |
Day 422 |
320 |
0.007 |
|
222.3 |
Day 422 |
321 |
0.007 |
|
266.7 |
Day 422 |
327 |
0.007 |
|
246.2 |
Day 422 |
330 |
0.007 |
|
240.4 |
Day 422 |
333 |
0.007 |
|
229.9 |
Day 422 |
340 |
0.007 |
|
187.8 |
Day 422 |
342 |
0.007 |
|
219.5 |
Day 422 |
343 |
0.007 |
|
235.5 |
Day 422 |
346 |
0.007 |
|
286.6 |
Day 422 |
348 |
0.007 |
|
238.8 |
Day 422 |
355 |
0.007 |
|
227.6 |
Day 422 |
359 |
0.007 |
|
216.3 |
Day 422 |
360 |
0.007 |
|
215.8 |
Day 422 |
361 |
0.007 |
|
244.6 |
Day 422 |
364 |
0.007 |
|
257.6 |
Day 422 |
366 |
0.007 |
|
211.9 |
Day 422 |
368 |
0.007 |
|
243.5 |
Day 422 |
369 |
0.007 |
|
230.6 |
Day 422 |
491 |
0.015 |
|
176.3 |
Day 422 |
493 |
0.015 |
|
206.3 |
Day 422 |
510 |
0.015 |
|
199.5 |
Day 422 |
515 |
0.015 |
|
219.3 |
Day 425 |
108 |
0 |
|
320 |
Day 425 |
109 |
0 |
|
288.1 |
Day 425 |
110 |
0 |
|
328 |
Day 425 |
111 |
0 |
|
292 |
Day 425 |
112 |
0 |
|
318.5 |
Day 425 |
113 |
0 |
|
270 |
Day 425 |
114 |
0 |
|
314.3 |
Day 425 |
115 |
0 |
|
286.7 |
Day 425 |
116 |
0 |
|
307.4 |
Day 425 |
117 |
0 |
|
323.3 |
Day 425 |
118 |
0 |
|
277.1 |
Day 425 |
119 |
0 |
|
307.3 |
Day 425 |
120 |
0 |
|
299.4 |
Day 425 |
218 |
0.003 |
|
286.7 |
Day 425 |
219 |
0.003 |
|
272.2 |
Day 425 |
221 |
0.003 |
|
301.3 |
Day 425 |
222 |
0.003 |
|
267.5 |
Day 425 |
224 |
0.003 |
|
294.8 |
Day 425 |
225 |
0.003 |
|
296.4 |
Day 425 |
226 |
0.003 |
|
297.5 |
Day 425 |
227 |
0.003 |
|
229.8 |
Day 425 |
228 |
0.003 |
|
290 |
Day 425 |
229 |
0.003 |
|
269.8 |
Day 425 |
370 |
0.007 |
|
192.1 |
Day 425 |
372 |
0.007 |
|
248.4 |
Day 425 |
373 |
0.007 |
|
235.9 |
Day 425 |
374 |
0.007 |
|
223.8 |
Day 425 |
377 |
0.007 |
|
231.8 |
Day 426 |
121 |
0 |
|
299.9 |
Day 426 |
122 |
0 |
|
262.7 |
Day 426 |
123 |
0 |
|
301.6 |
Day 426 |
124 |
0 |
|
296.7 |
Day 426 |
125 |
0 |
|
306 |
Day 426 |
126 |
0 |
|
331.3 |
Day 426 |
127 |
0 |
|
314.9 |
Day 426 |
128 |
0 |
|
283.2 |
Day 426 |
129 |
0 |
|
356.7 |
Day 426 |
130 |
0 |
|
288.5 |
Day 426 |
131 |
0 |
|
312.6 |
Day 426 |
132 |
0 |
|
292.3 |
Day 426 |
206 |
0.003 |
|
289.3 |
Day 426 |
209 |
0.003 |
|
257.3 |
Day 426 |
215 |
0.003 |
|
271.1 |
Day 426 |
230 |
0.003 |
|
248.3 |
Day 426 |
335 |
0.007 |
|
255.9 |
Day 426 |
375 |
0.007 |
|
247.1 |
Day 426 |
497 |
0.015 |
|
208.7 |
Day 427 |
133 |
0 |
|
283.4 |
Day 427 |
134 |
0 |
|
303.4 |
Day 427 |
135 |
0 |
|
261.2 |
Day 427 |
136 |
0 |
|
249 |
Day 427 |
137 |
0 |
|
328.4 |
Day 427 |
138 |
0 |
|
289.4 |
Day 427 |
139 |
0 |
|
339.9 |
Day 427 |
140 |
0 |
|
306.5 |
Abbreviations: |
NA: Not Available
|