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Long-Term Study Organ Weights Individual Animal

Study Information:

Chemical Name: Milk thistle extract
CASRN: ="84604-20-6"
Study Number: C20008
Study Length (Year Completed): (N/A)
Exposure Route: DOSED FEED
TDMS Number: 2000803
Sex: Female
Strain and Species: F 344/N Rats

Organ Weights Individual Animal Data
Measurement Time Animal Number Dose Group (PPM) Control Code Final Body Weight (g)
Day 80 325 25000 0
Day 200 250 0 0
Day 302 211 0 194.9
Day 434 220 0 0
Day 451 333 25000 260.8
Day 459 283 12500 0
Day 477 279 12500 242.1
Day 477 329 25000 293.3
Day 484 335 25000 202
Day 507 309 25000 252.7
Day 546 388 50000 289.2
Day 567 312 25000 186.6
Day 575 241 0 0
Day 592 251 12500 272.5
Day 599 257 12500 319.5
Day 609 297 12500 0
Day 613 379 50000 0
Day 618 244 0 193.3
Day 618 281 12500 0
Day 619 262 12500 281
Day 619 299 12500 201.7
Day 619 366 50000 225.4
Day 619 372 50000 230
Day 623 232 0 0
Day 637 206 0 0
Day 637 259 12500 0
Day 638 371 50000 0
Day 647 326 25000 268.8
Day 647 394 50000 171.9
Day 660 231 0 0
Day 660 271 12500 315.6
Day 660 288 12500 212.4
Day 660 314 25000 226
Day 664 359 50000 0
Day 667 323 25000 177.5
Day 667 389 50000 230.9
Day 672 258 12500 188
Day 674 385 50000 0
Day 676 302 25000 195.2
Day 687 202 0 204
Day 687 223 0 239
Day 687 347 25000 268.8
Day 693 353 50000 0
Day 703 310 25000 289.2
Day 703 311 25000 220.8
Day 703 320 25000 192.6
Day 703 393 50000 212.9
Day 710 217 0 200.3
Day 711 346 25000 215.5
Day 721 397 50000 202.8
Day 722 261 12500 238.6
Day 722 364 50000 189.3
Day 725 247 0 309.2
Day 725 256 12500 0
Day 725 337 25000 0
Day 729 351 50000 307.6
Day 729 352 50000 313
Day 729 354 50000 273.8
Day 729 355 50000 290.9
Day 729 361 50000 307
Day 729 362 50000 277.8
Day 729 363 50000 319.7
Day 729 365 50000 340.8
Day 732 207 0 282.7
Day 732 208 0 326.4
Day 732 209 0 349.2
Day 732 210 0 338.4
Day 732 221 0 314.8
Day 732 222 0 290.2
Day 732 224 0 318.6
Day 732 225 0 294.2
Day 732 233 0 325.8
Day 732 234 0 357.1
Day 732 235 0 338.9
Day 732 260 12500 283.1
Day 732 272 12500 333.6
Day 732 273 12500 337
Day 732 274 12500 333.5
Day 732 275 12500 317.5
Day 732 282 12500 349.9
Day 732 284 12500 314.1
Day 732 285 12500 349.3
Day 732 286 12500 315.1
Day 732 287 12500 316.3
Day 732 289 12500 349.3
Day 732 290 12500 321.5
Day 732 291 12500 319.1
Day 732 292 12500 343.3
Day 732 293 12500 375.4
Day 732 294 12500 341.8
Day 732 295 12500 317.4
Day 732 296 12500 0
Day 732 301 25000 276.3
Day 732 303 25000 307.4
Day 732 304 25000 286.7
Day 732 305 25000 283.7
Day 732 306 25000 319.7
Day 732 307 25000 326.3
Day 732 308 25000 251.4
Day 732 386 50000 309.2
Day 732 387 50000 292.4
Day 732 390 50000 317.3
Day 735 201 0 330.7
Day 735 203 0 337.7
Day 735 204 0 360.2
Day 735 205 0 311.1
Day 735 216 0 337.9
Day 735 218 0 344.3
Day 735 219 0 322.2
Day 735 226 0 335.9
Day 735 227 0 343
Day 735 228 0 343
Day 735 229 0 332.5
Day 735 230 0 303.3
Day 735 236 0 324.9
Day 735 237 0 342.6
Day 735 238 0 343.5
Day 735 239 0 329.5
Day 735 240 0 279.8
Day 735 242 0 326.4
Day 735 243 0 324.2
Day 735 245 0 340.9
Day 735 246 0 320.6
Day 735 248 0 332.6
Day 735 249 0 347.5
Day 735 266 12500 327.1
Day 735 267 12500 271.1
Day 735 268 12500 310.7
Day 735 269 12500 310.9
Day 735 270 12500 303.5
Day 735 298 12500 341
Day 735 300 12500 292.9
Day 735 313 25000 277.3
Day 735 315 25000 300.9
Day 735 316 25000 314.5
Day 735 317 25000 325.4
Day 735 318 25000 288.3
Day 735 319 25000 324.5
Day 735 321 25000 297.7
Day 735 322 25000 335
Day 735 324 25000 336.4
Day 735 331 25000 311.3
Day 735 332 25000 306.7
Day 735 334 25000 345.1
Day 735 381 50000 299
Day 735 382 50000 317.4
Day 735 383 50000 291
Day 735 384 50000 246.2
Day 735 391 50000 275.3
Day 735 392 50000 331.6
Day 735 395 50000 293.7
Day 736 212 0 325.9
Day 736 213 0 343.6
Day 736 214 0 299.2
Day 736 215 0 322.8
Day 736 252 12500 299.7
Day 736 253 12500 340.3
Day 736 254 12500 305.1
Day 736 255 12500 320.5
Day 736 263 12500 325.7
Day 736 264 12500 231.7
Day 736 265 12500 347.9
Day 736 276 12500 326.6
Day 736 277 12500 308.4
Day 736 278 12500 342.2
Day 736 280 12500 336.7
Day 736 327 25000 317.9
Day 736 328 25000 303.6
Day 736 330 25000 324.5
Day 736 336 25000 319.7
Day 736 338 25000 318.9
Day 736 339 25000 312.1
Day 736 340 25000 349.2
Day 736 341 25000 322
Day 736 342 25000 308.3
Day 736 343 25000 309
Day 736 344 25000 345.8
Day 736 345 25000 352.3
Day 736 348 25000 325
Day 736 349 25000 300.7
Day 736 350 25000 321
Day 736 356 50000 303.3
Day 736 357 50000 300.6
Day 736 358 50000 237
Day 736 360 50000 296.2
Day 736 367 50000 323
Day 736 368 50000 290.9
Day 736 369 50000 317.3
Day 736 370 50000 280.2
Day 736 373 50000 300.6
Day 736 374 50000 312
Day 736 375 50000 323.3
Day 736 376 50000 315.9
Day 736 377 50000 301.3
Day 736 378 50000 213.1
Day 736 380 50000 252.6
Day 736 396 50000 286.9
Day 736 398 50000 310.1
Day 736 399 50000 317.5
Day 736 400 50000 299.1
Abbreviations:
NA: Not Available