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Long-Term Study
Organ Weights Individual Animal
Study Information:
Chemical Name: | Scopolamine hydrobromide trihydrate |
CASRN: | ="6533-68-2" |
Study Number: | C03098C |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | GAVAGE |
TDMS Number: | 0512108 |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (MG/KG) |
Control Code |
Final Body Weight (g) |
Day 63 |
375 |
25 |
|
17.8 |
Day 108 |
302 |
0 |
|
33.3 |
Day 214 |
394 |
25 |
|
19.8 |
Day 456 |
230 |
0 |
|
37.7 |
Day 456 |
235 |
0 |
|
37.2 |
Day 456 |
238 |
0 |
|
40.9 |
Day 456 |
240 |
0 |
|
36.5 |
Day 456 |
247 |
0 |
|
37.9 |
Day 456 |
249 |
0 |
|
36.4 |
Day 456 |
253 |
0 |
|
39.7 |
Day 456 |
258 |
0 |
|
39.8 |
Day 456 |
264 |
0 |
|
38.4 |
Day 456 |
271 |
0 |
|
37.7 |
Day 456 |
339 |
25 |
|
36.8 |
Day 456 |
344 |
25 |
|
36.4 |
Day 456 |
347 |
25 |
|
36.2 |
Day 456 |
349 |
25 |
|
34.9 |
Day 456 |
355 |
25 |
|
33.4 |
Day 456 |
356 |
25 |
|
36 |
Day 456 |
367 |
25 |
|
36.8 |
Day 456 |
378 |
25 |
|
39.4 |
Day 456 |
381 |
25 |
|
35.9 |
Day 456 |
388 |
25 |
|
39.9 |
Day 502 |
385 |
25 |
|
26 |
Day 515 |
280 |
0 |
|
29.2 |
Day 620 |
295 |
0 |
|
23.6 |
Day 722 |
221 |
0 |
|
34.1 |
Day 722 |
222 |
0 |
|
33.4 |
Day 722 |
223 |
0 |
|
34.7 |
Day 722 |
224 |
0 |
|
34.5 |
Day 722 |
225 |
0 |
|
34.3 |
Day 722 |
226 |
0 |
|
35.4 |
Day 722 |
227 |
0 |
|
38.9 |
Day 722 |
228 |
0 |
|
34.2 |
Day 722 |
229 |
0 |
|
37.6 |
Day 722 |
231 |
0 |
|
35.1 |
Day 722 |
232 |
0 |
|
33.9 |
Day 722 |
233 |
0 |
|
39.4 |
Day 722 |
234 |
0 |
|
37 |
Day 722 |
236 |
0 |
|
34.5 |
Day 722 |
237 |
0 |
|
35.4 |
Day 722 |
239 |
0 |
|
38.7 |
Day 722 |
241 |
0 |
|
34.7 |
Day 722 |
242 |
0 |
|
33.7 |
Day 722 |
243 |
0 |
|
33.5 |
Day 722 |
244 |
0 |
|
35.1 |
Day 722 |
245 |
0 |
|
34.8 |
Day 722 |
246 |
0 |
|
36.4 |
Day 722 |
248 |
0 |
|
35.7 |
Day 722 |
250 |
0 |
|
37.2 |
Day 722 |
251 |
0 |
|
37.5 |
Day 722 |
252 |
0 |
|
34.4 |
Day 722 |
254 |
0 |
|
38.2 |
Day 722 |
255 |
0 |
|
35.2 |
Day 722 |
256 |
0 |
|
32 |
Day 722 |
257 |
0 |
|
32.1 |
Day 722 |
259 |
0 |
|
35.5 |
Day 722 |
260 |
0 |
|
32.8 |
Day 722 |
261 |
0 |
|
31.2 |
Day 722 |
262 |
0 |
|
37.9 |
Day 722 |
263 |
0 |
|
34.7 |
Day 722 |
265 |
0 |
|
35.1 |
Day 722 |
266 |
0 |
|
34.1 |
Day 722 |
267 |
0 |
|
31.9 |
Day 722 |
268 |
0 |
|
35.1 |
Day 722 |
269 |
0 |
|
39.6 |
Day 722 |
270 |
0 |
|
33.7 |
Day 722 |
272 |
0 |
|
39.2 |
Day 722 |
273 |
0 |
|
38.2 |
Day 722 |
274 |
0 |
|
32.5 |
Day 722 |
275 |
0 |
|
32.5 |
Day 722 |
276 |
0 |
|
32.6 |
Day 722 |
277 |
0 |
|
33.2 |
Day 722 |
278 |
0 |
|
38.6 |
Day 722 |
279 |
0 |
|
33.4 |
Day 722 |
331 |
25 |
|
34.1 |
Day 722 |
332 |
25 |
|
32.9 |
Day 722 |
333 |
25 |
|
32.1 |
Day 722 |
334 |
25 |
|
35.2 |
Day 722 |
335 |
25 |
|
35.4 |
Day 722 |
336 |
25 |
|
31.3 |
Day 722 |
337 |
25 |
|
33.9 |
Day 722 |
338 |
25 |
|
35.7 |
Day 722 |
340 |
25 |
|
31.6 |
Day 722 |
341 |
25 |
|
32.5 |
Day 722 |
342 |
25 |
|
34 |
Day 722 |
343 |
25 |
|
32.8 |
Day 722 |
345 |
25 |
|
32.2 |
Day 722 |
346 |
25 |
|
36 |
Day 722 |
348 |
25 |
|
36.6 |
Day 722 |
350 |
25 |
|
31 |
Day 722 |
351 |
25 |
|
32.8 |
Day 722 |
352 |
25 |
|
35.1 |
Day 722 |
353 |
25 |
|
32.2 |
Day 722 |
354 |
25 |
|
32.6 |
Day 722 |
357 |
25 |
|
34.5 |
Day 722 |
358 |
25 |
|
34.4 |
Day 722 |
359 |
25 |
|
26.6 |
Day 722 |
360 |
25 |
|
31.2 |
Day 722 |
361 |
25 |
|
34.5 |
Day 722 |
362 |
25 |
|
30.8 |
Day 722 |
363 |
25 |
|
30.7 |
Day 722 |
364 |
25 |
|
32.7 |
Day 722 |
365 |
25 |
|
36 |
Day 722 |
366 |
25 |
|
34.4 |
Day 722 |
368 |
25 |
|
30.2 |
Day 722 |
369 |
25 |
|
34.5 |
Day 722 |
370 |
25 |
|
32 |
Day 722 |
371 |
25 |
|
32.5 |
Day 722 |
372 |
25 |
|
35.4 |
Day 722 |
373 |
25 |
|
32.5 |
Day 722 |
374 |
25 |
|
30 |
Day 722 |
376 |
25 |
|
32.7 |
Day 722 |
377 |
25 |
|
33.1 |
Day 722 |
379 |
25 |
|
32 |
Day 722 |
380 |
25 |
|
28.5 |
Day 722 |
382 |
25 |
|
32.7 |
Day 722 |
383 |
25 |
|
31.7 |
Day 722 |
384 |
25 |
|
32.2 |
Day 722 |
386 |
25 |
|
33.1 |
Day 722 |
387 |
25 |
|
32.8 |
Day 722 |
389 |
25 |
|
33.6 |
Day 722 |
390 |
25 |
|
33 |
Day 762 |
285 |
0 |
|
37.4 |
Day 784 |
315 |
0 |
|
31.1 |
Day 784 |
398 |
25 |
|
27.8 |
Day 799 |
308 |
0 |
|
39.2 |
Day 819 |
408 |
25 |
|
24.4 |
Day 859 |
306 |
0 |
|
32.3 |
Day 866 |
320 |
0 |
|
34 |
Day 880 |
431 |
25 |
|
25.2 |
Day 892 |
438 |
25 |
|
25.5 |
Day 898 |
309 |
0 |
|
20.2 |
Day 898 |
420 |
25 |
|
26.8 |
Day 924 |
421 |
25 |
|
20.5 |
Day 931 |
407 |
25 |
|
31.2 |
Day 933 |
405 |
25 |
|
20.8 |
Day 936 |
313 |
0 |
|
30.1 |
Day 941 |
305 |
0 |
|
33.3 |
Day 953 |
397 |
25 |
|
20.8 |
Day 957 |
426 |
25 |
|
18.8 |
Day 964 |
422 |
25 |
|
28.4 |
Day 972 |
283 |
0 |
|
29.3 |
Day 974 |
317 |
0 |
|
27.3 |
Day 987 |
312 |
0 |
|
28.1 |
Day 1002 |
282 |
0 |
|
34.1 |
Day 1016 |
288 |
0 |
|
27 |
Day 1016 |
324 |
0 |
|
40 |
Day 1019 |
314 |
0 |
|
47.9 |
Day 1020 |
325 |
0 |
|
23.8 |
Day 1036 |
392 |
25 |
|
34.9 |
Day 1045 |
293 |
0 |
|
36.4 |
Day 1050 |
316 |
0 |
|
25.9 |
Day 1063 |
298 |
0 |
|
26.7 |
Day 1065 |
291 |
0 |
|
21.9 |
Day 1086 |
281 |
0 |
|
34.7 |
Day 1086 |
284 |
0 |
|
36 |
Day 1086 |
286 |
0 |
|
32.8 |
Day 1086 |
287 |
0 |
|
31.9 |
Day 1086 |
289 |
0 |
|
33.9 |
Day 1086 |
290 |
0 |
|
36.1 |
Day 1086 |
292 |
0 |
|
32.8 |
Day 1086 |
294 |
0 |
|
32.9 |
Day 1086 |
296 |
0 |
|
34.1 |
Day 1086 |
297 |
0 |
|
36 |
Day 1086 |
299 |
0 |
|
33.8 |
Day 1086 |
300 |
0 |
|
32.7 |
Day 1086 |
301 |
0 |
|
32.2 |
Day 1086 |
303 |
0 |
|
31.9 |
Day 1086 |
304 |
0 |
|
34.4 |
Day 1086 |
307 |
0 |
|
33.3 |
Day 1086 |
310 |
0 |
|
34.6 |
Day 1086 |
311 |
0 |
|
35.8 |
Day 1086 |
318 |
0 |
|
33.1 |
Day 1086 |
319 |
0 |
|
37.9 |
Day 1086 |
321 |
0 |
|
35.2 |
Day 1086 |
322 |
0 |
|
34.1 |
Day 1086 |
323 |
0 |
|
31.6 |
Day 1086 |
326 |
0 |
|
33.5 |
Day 1086 |
327 |
0 |
|
32.5 |
Day 1086 |
328 |
0 |
|
34.5 |
Day 1086 |
329 |
0 |
|
30.5 |
Day 1086 |
330 |
0 |
|
33.1 |
Day 1086 |
391 |
25 |
|
33.1 |
Day 1086 |
393 |
25 |
|
33.1 |
Day 1086 |
395 |
25 |
|
32.4 |
Day 1086 |
396 |
25 |
|
31.2 |
Day 1086 |
399 |
25 |
|
32.2 |
Day 1086 |
400 |
25 |
|
29.8 |
Day 1086 |
401 |
25 |
|
30.4 |
Day 1086 |
402 |
25 |
|
29.3 |
Day 1086 |
403 |
25 |
|
31.7 |
Day 1086 |
404 |
25 |
|
31.9 |
Day 1086 |
406 |
25 |
|
28.1 |
Day 1086 |
409 |
25 |
|
31.6 |
Day 1086 |
410 |
25 |
|
29.4 |
Day 1086 |
411 |
25 |
|
31 |
Day 1086 |
412 |
25 |
|
33.5 |
Day 1086 |
413 |
25 |
|
32.3 |
Day 1086 |
414 |
25 |
|
29.5 |
Day 1086 |
415 |
25 |
|
31.1 |
Day 1086 |
416 |
25 |
|
32.5 |
Day 1086 |
417 |
25 |
|
31.7 |
Day 1086 |
418 |
25 |
|
30.6 |
Day 1086 |
419 |
25 |
|
30.6 |
Day 1086 |
423 |
25 |
|
32.9 |
Day 1086 |
424 |
25 |
|
32.1 |
Day 1086 |
425 |
25 |
|
30.8 |
Day 1086 |
427 |
25 |
|
30.5 |
Day 1086 |
428 |
25 |
|
32.4 |
Day 1086 |
429 |
25 |
|
34.7 |
Day 1086 |
430 |
25 |
|
32.4 |
Day 1086 |
432 |
25 |
|
30.4 |
Day 1086 |
433 |
25 |
|
31.5 |
Day 1086 |
434 |
25 |
|
33.2 |
Day 1086 |
435 |
25 |
|
29.7 |
Day 1086 |
436 |
25 |
|
29.4 |
Day 1086 |
437 |
25 |
|
31.2 |
Day 1086 |
439 |
25 |
|
32.9 |
Day 1086 |
440 |
25 |
|
34.5 |
Abbreviations: |
NA: Not Available
|