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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 1,1-Dichloroethane
CASRN: ="75-34-3"
Study Number: C04535
Exposure Route: Gavage
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Untreated Control 17 NA 2_013 95.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Untreated Control 17 NA 2_005 95.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Vehicle Control 19 NA 1_004 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 000.9 G/KG 49 NA 3_016 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 000.9 G/KG 49 NA 3_017 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 000.9 G/KG 49 NA 3_019 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 000.9 G/KG 49 NA 3_021 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 000.9 G/KG 49 NA 3_022 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 000.9 G/KG 49 NA 3_025 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 000.9 G/KG 49 NA 3_032 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 000.9 G/KG 49 NA 3_042 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 001.8 G/KG 47 NA 4_004 96.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 001.8 G/KG 47 NA 4_011 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 001.8 G/KG 47 NA 4_013 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 001.8 G/KG 47 NA 4_021 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 001.8 G/KG 47 NA 4_022 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 001.8 G/KG 47 NA 4_023 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 001.8 G/KG 47 NA 4_041 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 001.8 G/KG 47 NA 4_042 96.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Salivary gland 001.8 G/KG 47 NA 4_001 96.00 1 Squamous Cell Carcinoma Scheduled Sacrifice
Alimentary System Stomach Vehicle Control 19 NA 1_013 96.00 1 Squamous Cell Carcinoma Natural Death
Alimentary System Stomach 000.9 G/KG 49 NA 3_036 96.00 1 Squamous Cell Carcinoma Natural Death
All Others Unspecified Back 000.9 G/KG NA NA 3_008 96.00 1 Fibrosarcoma Natural Death
All Others Unspecified Back 000.9 G/KG NA NA 3_050 96.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Back 000.9 G/KG NA NA 3_026 96.00 1 Fibrosarcoma Scheduled Sacrifice
All Others Unspecified Groin 000.9 G/KG NA NA 3_003 96.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 1_003 96.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 000.9 G/KG NA NA 3_001 96.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 000.9 G/KG NA NA 3_031 96.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 001.8 G/KG NA NA 4_044 96.00 1 Lymphoma, Histiocytic-Malignant Type Moribund Sacrifice
All Others Unspecified 000.9 G/KG NA NA 3_049 96.00 1 Fibrosarcoma Scheduled Sacrifice
Endocrine System Thyroid 001.8 G/KG 47 NA 4_014 96.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Genital System Testis 000.9 G/KG 49 NA 3_045 96.00 1 Interstitial-Cell Tumor Scheduled Sacrifice
Hematopoietic System Lymph node Renal Lymph Node Vehicle Control 19 NA 1_013 96.00 1 Squamous Cell Carcinoma, Metastatic Natural Death
Hematopoietic System Spleen 000.9 G/KG 49 NA 3_003 96.00 1 Hemangiosarcoma Scheduled Sacrifice
Hematopoietic System Spleen 001.8 G/KG 47 NA 4_014 96.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Integumentary System Skin Back Untreated Control 17 NA 2_005 95.00 1 Fibrosarcoma Scheduled Sacrifice
Integumentary System Skin Neck 001.8 G/KG 47 NA 4_001 96.00 1 Squamous Cell Carcinoma Scheduled Sacrifice
Respiratory System Lung 000.9 G/KG 49 NA 3_050 96.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 001.8 G/KG 47 NA 4_018 96.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 001.8 G/KG 47 NA 4_047 96.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 001.8 G/KG 47 NA 4_032 96.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 001.8 G/KG 47 NA 4_034 96.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Urinary System Kidney Vehicle Control 19 NA 1_008 96.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
Urinary System Kidney 000.9 G/KG 49 NA 3_005 96.00 1 Tubular-Cell Adenoma Natural Death
Urinary System Kidney 000.9 G/KG 49 NA 3_033 96.00 1 Tubular-Cell Adenoma Natural Death
Urinary System Kidney 000.9 G/KG 49 NA 3_022 96.00 1 Tubular-Cell Adenoma Scheduled Sacrifice