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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 2,3,7,8-Tetrachlorodibenzo-p-dioxin
CASRN: ="1746-01-6"
Study Number: C03714B
Exposure Route: Topical Application
TDMS Number:
Sex: Female
Strain and Species: Swiss Webster Mice

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Untreated Control 30 NA 4_014 111.00 1 Hemangiosarcoma Natural Death
Alimentary System Liver Vehicle Control 82 NA 5_008 111.00 1 Adenocarcinoma, Nos, Metastatic Natural Death
Alimentary System Liver Vehicle Control 82 NA 5_010 111.00 1 Hemangiosarcoma Scheduled Sacrifice
Alimentary System Liver 050.0 UG 28 NA 3_006 111.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Pancreas Duct Nos Vehicle Control 80 NA 5_029 111.00 1 Sarcoma, Nos Natural Death
Alimentary System Pancreas Vehicle Control 80 NA 5_008 111.00 1 Adenocarcinoma, Nos, Metastatic Natural Death
Alimentary System Pancreas Vehicle Control 80 NA 5_025 111.00 1 Lipoma Scheduled Sacrifice
Alimentary System Salivary gland Parotid Gland Nos Vehicle Control NA NA 5_008 111.00 1 Mixed Tumor, Benign Natural Death
Alimentary System Stomach Serosa Vehicle Control 82 NA 5_029 111.00 1 Sarcoma, Nos Natural Death
All Others Unspecified Back 005.0 NG NA NA 1_033 111.00 1 Fibroma Natural Death
All Others Unspecified Back 005.0 NG NA NA 1_035 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified Back 005.0 NG NA NA 1_039 111.00 1 Fibrosarcoma Scheduled Sacrifice
All Others Unspecified Back 050.0 UG NA NA 3_017 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified Head 050.0 UG NA NA 3_029 111.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Head 050.0 UG NA NA 3_009 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified Leg Untreated Control NA NA 2_013 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified Leg Vehicle Control NA NA 5_028 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified Leg 005.0 NG NA NA 1_002 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 4_006 111.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 2_003 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 2_004 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 2_011 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 4_009 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_007 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_011 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_012 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_021 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_029 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_031 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_046 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_051 111.00 1 Thymoma, Metastatic Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 2_017 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 4_001 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 4_008 111.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 4_010 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 4_015 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_006 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_013 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_018 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_025 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_036 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 5_040 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_004 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_004 111.00 1 Fibrosarcoma, Metastatic Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_006 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_008 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_013 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_022 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_029 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_030 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_035 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_040 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 005.0 NG NA NA 1_007 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 UG NA NA 3_022 111.00 1 Thymoma, Metastatic Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 UG NA NA 3_001 111.00 1 Fibrosarcoma, Metastatic Natural Death
All Others Unspecified Multiple Organs Nos 050.0 UG NA NA 3_010 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 050.0 UG NA NA 3_011 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 050.0 UG NA NA 3_012 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 050.0 UG NA NA 3_020 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 050.0 UG NA NA 3_005 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 UG NA NA 3_030 111.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Vehicle Control NA NA 5_011 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified 005.0 NG NA NA 1_001 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified 005.0 NG NA NA 1_022 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified 005.0 NG NA NA 1_030 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified 005.0 NG NA NA 1_032 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified 005.0 NG NA NA 1_038 111.00 1 Fibrosarcoma Scheduled Sacrifice
All Others Unspecified 005.0 NG NA NA 1_038 111.00 1 Myxoma Scheduled Sacrifice
All Others Unspecified 050.0 UG NA NA 3_001 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified 050.0 UG NA NA 3_003 111.00 1 Fibrosarcoma Natural Death
All Others Unspecified 050.0 UG NA NA 3_007 111.00 1 Fibrosarcoma Natural Death
Cardiovascular System Heart Atrium 005.0 NG 27 NA 1_038 111.00 1 Fibrosarcoma, Metastatic Scheduled Sacrifice
Endocrine System Adrenal gland Untreated Control 30 NA 4_006 111.00 1 Cortical Adenoma Moribund Sacrifice
General Body System Peritoneum Peritoneal Cavity Nos 005.0 NG NA NA 1_038 111.00 1 Fibrosarcoma, Metastatic Scheduled Sacrifice
Genital System Ovary Untreated Control 28 NA 4_005 111.00 1 Luteoma Natural Death
Genital System Ovary Vehicle Control 66 NA 5_001 111.00 1 Granulosa-Cell Tumor Natural Death
Genital System Ovary Vehicle Control 66 NA 5_007 111.00 1 Lipoma Natural Death
Genital System Ovary Vehicle Control 66 NA 5_046 111.00 1 Hemangioma Natural Death
Genital System Ovary 005.0 NG 22 NA 1_021 111.00 1 Granulosa-Cell Tumor Natural Death
Genital System Ovary 050.0 UG 29 NA 3_002 111.00 1 Leiomyosarcoma, Invasive Natural Death
Genital System Ovary 050.0 UG 29 NA 3_004 111.00 1 Hemangioma Natural Death
Genital System Ovary 050.0 UG 29 NA 3_009 111.00 1 Papillary Adenoma Natural Death
Genital System Ovary 050.0 UG 29 NA 3_021 111.00 1 Leiomyosarcoma, Invasive Natural Death
Genital System Uterus Cervix Uteri Untreated Control 30 NA 4_015 111.00 1 Leiomyoma Scheduled Sacrifice
Genital System Uterus Cervix Uteri 050.0 UG 29 NA 3_016 111.00 1 Leiomyoma Scheduled Sacrifice
Genital System Uterus Untreated Control 30 NA 4_011 111.00 1 Leiomyoma Natural Death
Genital System Uterus Untreated Control 30 NA 4_019 111.00 1 Leiomyoma Natural Death
Genital System Uterus Vehicle Control 72 NA 5_008 111.00 1 Adenocarcinoma, Nos Natural Death
Genital System Uterus Vehicle Control 72 NA 5_006 111.00 1 Hemangioma Scheduled Sacrifice
Genital System Uterus 005.0 NG 25 NA 1_015 111.00 1 Endometrial Stromal Polyp Natural Death
Genital System Uterus 005.0 NG 25 NA 1_029 111.00 1 Leiomyoma Natural Death
Genital System Uterus 005.0 NG 25 NA 1_040 111.00 1 Leiomyoma Natural Death
Genital System Uterus 050.0 UG 29 NA 3_002 111.00 1 Leiomyosarcoma Natural Death
Genital System Uterus 050.0 UG 29 NA 3_020 111.00 1 Leiomyoma Natural Death
Genital System Uterus 050.0 UG 29 NA 3_021 111.00 1 Leiomyosarcoma Natural Death
Genital System Vagina 050.0 UG NA NA 3_002 111.00 1 Leiomyosarcoma, Invasive Natural Death
Genital System Vagina 050.0 UG NA NA 3_021 111.00 1 Leiomyosarcoma, Invasive Natural Death
Hematopoietic System Bone marrow Vehicle Control 74 NA 5_012 111.00 1 Fibroma Natural Death
Hematopoietic System Lymph node Cervical Lymph Node Nos 005.0 NG 20 NA 1_002 111.00 1 Fibrosarcoma, Metastatic Natural Death
Hematopoietic System Lymph node Pancreatic Lymph Node Vehicle Control 60 NA 5_004 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
Hematopoietic System Lymph node Thoracic Lymph Node 050.0 UG 25 NA 3_014 111.00 1 Alveolar/Bronchiolar Carcinoma, Invasive Natural Death
Hematopoietic System Lymph node Tracheal Lymph Node 050.0 UG 25 NA 3_014 111.00 1 Alveolar/Bronchiolar Carcinoma, Metastatic Natural Death
Hematopoietic System Lymph node 005.0 NG 20 NA 1_035 111.00 1 Fibrosarcoma, Metastatic Natural Death
Hematopoietic System Lymph node 050.0 UG 25 NA 3_013 111.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen Vehicle Control 80 NA 5_008 111.00 1 Adenocarcinoma, Nos, Metastatic Natural Death
Hematopoietic System Spleen Vehicle Control 80 NA 5_011 111.00 1 Fibroma Natural Death
Hematopoietic System Spleen 005.0 NG 24 NA 1_001 111.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
Hematopoietic System Thymus Vehicle Control 78 NA 5_051 111.00 1 Thymoma, Malignant Natural Death
Hematopoietic System Thymus 005.0 NG 22 NA 1_001 111.00 1 Fibrosarcoma, Metastatic Natural Death
Hematopoietic System Thymus 050.0 UG 28 NA 3_018 111.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice
Hematopoietic System Thymus 050.0 UG 28 NA 3_022 111.00 1 Thymoma, Malignant Moribund Sacrifice
Hematopoietic System Thymus 050.0 UG 28 NA 3_001 111.00 1 Alveolar/Bronchiolar Carcinoma, Metastatic Natural Death
Integumentary System Skin Back 050.0 UG 25 NA 3_006 111.00 1 Fibrosarcoma Natural Death
Integumentary System Skin Eyelid Nos 050.0 UG 25 NA 3_005 111.00 1 Keratoacanthoma Scheduled Sacrifice
Integumentary System Skin 050.0 UG 25 NA 3_028 111.00 1 Fibrosarcoma Moribund Sacrifice
Musculoskeletal System Bone Coccyx 050.0 UG NA NA 3_003 111.00 1 Fibrosarcoma, Metastatic Natural Death
Respiratory System Lung Pleural Cavity Nos 005.0 NG NA NA 1_038 111.00 1 Fibrosarcoma, Metastatic Scheduled Sacrifice
Respiratory System Lung Untreated Control 24 NA 2_016 111.00 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung Untreated Control 30 NA 4_006 111.00 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung Vehicle Control 82 NA 5_005 111.00 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung Untreated Control 24 NA 2_018 111.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Vehicle Control 82 NA 5_008 111.00 1 Adenocarcinoma, Nos, Metastatic Natural Death
Respiratory System Lung Vehicle Control 82 NA 5_012 111.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Vehicle Control 82 NA 5_017 111.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Vehicle Control 82 NA 5_017 111.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung Vehicle Control 82 NA 5_028 111.00 1 Fibrosarcoma, Metastatic Natural Death
Respiratory System Lung Vehicle Control 82 NA 5_034 111.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung Vehicle Control 82 NA 5_046 111.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung Untreated Control 30 NA 4_012 111.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 30 NA 4_015 111.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Vehicle Control 82 NA 5_026 111.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Vehicle Control 82 NA 5_027 111.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Vehicle Control 82 NA 5_036 111.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 005.0 NG 25 NA 1_001 111.00 1 Fibrosarcoma, Metastatic Natural Death
Respiratory System Lung 005.0 NG 25 NA 1_002 111.00 1 Fibrosarcoma, Metastatic Natural Death
Respiratory System Lung 005.0 NG 25 NA 1_006 111.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 005.0 NG 25 NA 1_021 111.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 005.0 NG 25 NA 1_035 111.00 1 Fibrosarcoma, Metastatic Natural Death
Respiratory System Lung 005.0 NG 25 NA 1_038 111.00 1 Fibrosarcoma, Metastatic Scheduled Sacrifice
Respiratory System Lung 050.0 UG 28 NA 3_001 111.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 050.0 UG 28 NA 3_002 111.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 050.0 UG 28 NA 3_008 111.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 050.0 UG 28 NA 3_014 111.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 050.0 UG 28 NA 3_019 111.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 UG 28 NA 3_026 111.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Urinary System Genitourinary tract Vehicle Control NA NA 5_024 111.00 1 Fibrosarcoma Natural Death
Urinary System Urinary bladder 050.0 UG NA NA 3_002 111.00 1 Leiomyosarcoma, Invasive Natural Death
Urinary System Urinary bladder 050.0 UG NA NA 3_021 111.00 1 Leiomyosarcoma, Invasive Natural Death