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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 5-Azacytidine
CASRN: ="320-67-2"
Study Number: C01569
Exposure Route: Intraperitoneal Injection
TDMS Number:
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Untreated Control 15 NA 4_012 87.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 010.0 ML/KG 29 NA 2_051 87.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
Alimentary System Liver 010.0 ML/KG 29 NA 2_011 87.00 1 Leiomyosarcoma, Metastatic Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 4_018 87.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_036 87.00 1 Sarcoma, Granulocytic Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_037 87.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_043 87.00 1 Sarcoma, Granulocytic Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_026 87.00 1 Sarcoma, Granulocytic Natural Death
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_033 87.00 1 Sarcoma, Granulocytic Natural Death
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_052 87.00 1 Sarcoma, Granulocytic Natural Death
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_054 87.00 1 Leukemia, Granulocytic Natural Death
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_016 87.00 1 Sarcoma, Granulocytic Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_021 87.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_027 87.00 1 Sarcoma, Granulocytic Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_031 87.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_032 87.00 1 Lymphoma, Undifferentiated-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_041 87.00 1 Sarcoma, Granulocytic Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_053 87.00 1 Sarcoma, Granulocytic Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 010.0 ML/KG NA NA 2_056 87.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified 010.0 ML/KG NA NA 1_051 66.00 1 Basal-Cell Carcinoma Moribund Sacrifice
Cardiovascular System Heart 010.0 ML/KG 28 NA 2_051 87.00 1 Sarcoma, Nos Natural Death
Endocrine System Adrenal gland 010.0 ML/KG 27 NA 2_011 87.00 1 Leiomyosarcoma, Metastatic Scheduled Sacrifice
General Body System Peritoneum 010.0 ML/KG NA NA 2_011 87.00 1 Leiomyosarcoma, Metastatic Scheduled Sacrifice
Genital System Uterus 010.0 ML/KG 28 NA 2_011 87.00 1 Leiomyosarcoma Scheduled Sacrifice
Genital System Uterus 010.0 ML/KG 28 NA 2_035 87.00 1 Leiomyosarcoma Scheduled Sacrifice
Genital System Uterus 010.0 ML/KG 28 NA 2_044 87.00 1 Sarcoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland 010.0 ML/KG 5 NA 2_057 87.00 1 Adenocarcinoma, Nos Moribund Sacrifice
Integumentary System Mammary gland 010.0 ML/KG 5 NA 2_015 87.00 1 Adenocarcinoma, Nos Natural Death
Respiratory System Lung Pleura Nos 010.0 ML/KG NA NA 2_011 87.00 1 Leiomyosarcoma, Metastatic Scheduled Sacrifice
Respiratory System Lung Vehicle Control 13 NA 3_011 87.00 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung Untreated Control 15 NA 4_012 87.00 1 Undifferentiated Carcinoma, Metastatic Scheduled Sacrifice
Respiratory System Lung Vehicle Control 13 NA 3_017 87.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 010.0 ML/KG 28 NA 2_043 87.00 1 Basal-Cell Carcinoma, Metastatic Moribund Sacrifice
Respiratory System Lung 010.0 ML/KG 28 NA 2_051 87.00 1 Sarcoma, Nos, Metastatic Natural Death
Special Senses System Ear Canal 010.0 ML/KG 1 NA 2_043 87.00 1 Basal-Cell Carcinoma Moribund Sacrifice
Urinary System Kidney 010.0 ML/KG 29 NA 2_046 87.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice