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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Asbestos, amosite
CASRN: ="12172-73-5"
Study Number: C60253B
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Female
Strain and Species: Syrian Golden

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Large Anus Nos 10000 PPM NA NA 2_753 96.00 1 Squamous Cell Papilloma Natural Death
Alimentary System Intestine Large Rectum Untreated Control 113 NA 1_362 87.00 1 Adenoma, Nos Natural Death
Alimentary System Pancreas Islets Untreated Control 115 NA 1_141 87.00 1 Islet-Cell Adenoma Natural Death
Alimentary System Pancreas Islets Untreated Control 115 NA 1_261 87.00 1 Islet-Cell Adenoma Natural Death
Alimentary System Pancreas Islets Untreated Control 115 NA 1_363 87.00 1 Islet-Cell Adenoma Natural Death
Alimentary System Pancreas Islets 10000 PPM 222 NA 2_891 96.00 1 Islet-Cell Adenoma Natural Death
Alimentary System Pancreas Islets 10000 PPM 222 NA 2_903 96.00 1 Islet-Cell Adenoma Natural Death
Alimentary System Stomach Cardiac Stomach 10000 PPM 236 NA 2_563 96.00 1 Papilloma, Nos Moribund Sacrifice
Alimentary System Stomach Cardiac Stomach 10000 PPM 236 NA 2_241 96.00 1 Papilloma, Nos Natural Death
Alimentary System Stomach 10000 PPM 236 NA 2_353 96.00 1 Papilloma, Nos Natural Death
All Others Unspecified Leg 10000 PPM NA NA 2_751 96.00 1 Fibrosarcoma Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 1_071 87.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 1_222 87.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 2_751 96.00 1 Fibrosarcoma, Metastatic Natural Death
All Others Unspecified 10000 PPM NA NA 2_322 96.00 1 Fibrosarcoma Moribund Sacrifice
Endocrine System Adrenal gland Untreated Control 118 NA 1_081 87.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland Untreated Control 118 NA 1_241 87.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland 10000 PPM 234 NA 2_081 96.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland 10000 PPM 234 NA 2_232 96.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland 10000 PPM 234 NA 2_282 96.00 1 Pheochromocytoma Natural Death
Endocrine System Adrenal gland 10000 PPM 234 NA 2_442 96.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland 10000 PPM 234 NA 2_573 96.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland 10000 PPM 234 NA 2_582 96.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland 10000 PPM 234 NA 2_633 96.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland 10000 PPM 234 NA 2_702 96.00 1 Pheochromocytoma Natural Death
Endocrine System Parathyroid gland Untreated Control 61 NA 1_481 87.00 1 Adenoma, Nos Natural Death
Endocrine System Parathyroid gland 10000 PPM 141 NA 2_833 96.00 1 Adenoma, Nos Natural Death
Endocrine System Thyroid Untreated Control 106 NA 1_482 87.00 1 C-Cell Adenoma Natural Death
Endocrine System Thyroid 10000 PPM 215 NA 2_132 96.00 1 C-Cell Adenoma Natural Death
Endocrine System Thyroid 10000 PPM 215 NA 2_173 96.00 1 C-Cell Adenoma Natural Death
Endocrine System Thyroid 10000 PPM 215 NA 2_402 96.00 1 C-Cell Carcinoma Natural Death
Endocrine System Thyroid 10000 PPM 215 NA 2_443 96.00 1 C-Cell Adenoma Natural Death
Endocrine System Thyroid 10000 PPM 215 NA 2_863 96.00 1 C-Cell Adenoma Natural Death
Genital System Ovary Untreated Control 117 NA 1_073 87.00 1 Hemangioma Natural Death
Genital System Ovary Untreated Control 117 NA 1_231 87.00 1 Granulosa-Cell Tumor Natural Death
Genital System Uterus Endometrium Untreated Control 119 NA 1_403 87.00 1 Adenoma, Nos Natural Death
Genital System Uterus Untreated Control 119 NA 1_173 87.00 1 Papillary Carcinoma Natural Death
Genital System Uterus 10000 PPM 236 NA 2_672 96.00 1 Papillary Carcinoma Natural Death
Genital System Vagina 10000 PPM NA NA 2_762 96.00 1 Papilloma, Nos Natural Death
Hematopoietic System Lymph node Mesenteric Lymph Node 10000 PPM 223 NA 2_501 96.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
Hematopoietic System Lymph node Renal Lymph Node 10000 PPM 236 NA 2_631 96.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
Hematopoietic System Lymph node 10000 PPM 236 NA 2_442 96.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
Hematopoietic System Spleen 10000 PPM 237 NA 2_071 96.00 1 Hemangiosarcoma Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 237 NA 2_322 96.00 1 Fibrosarcoma, Metastatic Moribund Sacrifice
Hematopoietic System Spleen 10000 PPM 237 NA 2_153 96.00 1 Hemangioma Natural Death
Hematopoietic System Spleen 10000 PPM 237 NA 2_612 96.00 1 Hemangiosarcoma Natural Death
Integumentary System Mammary gland Untreated Control 125 NA 1_391 87.00 1 Fibroadenoma Natural Death
Respiratory System Lung 10000 PPM 234 NA 2_322 96.00 1 Fibrosarcoma, Metastatic Moribund Sacrifice
Urinary System Kidney 10000 PPM 236 NA 2_491 96.00 1 Sarcoma, Nos, Metastatic Natural Death
Urinary System Urinary bladder 10000 PPM NA NA 2_911 96.00 1 Transitional-Cell Papilloma Moribund Sacrifice