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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Bisphenol A
CASRN: ="80-05-7"
Study Number: C50635
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Jejunum 5000 PPM 35 NA 2_012 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Alimentary System Intestine Small Jejunum 10000 PPM 37 NA 1_011 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Alimentary System Intestine Small Peyers Patch 10000 PPM NA NA 1_027 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Alimentary System Liver 5000 PPM 48 NA 2_023 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 48 NA 1_040 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 48 NA 1_048 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 48 NA 1_050 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Stomach Forestomach 5000 PPM 47 NA 2_022 112.00 1 Squamous Cell Papilloma Scheduled Sacrifice
Alimentary System Stomach 5000 PPM 47 NA 2_017 112.00 1 Adenomatous Polyp, Nos Scheduled Sacrifice
Alimentary System Stomach 5000 PPM 47 NA 2_019 112.00 1 Adenomatous Polyp, Nos Scheduled Sacrifice
All Others Unspecified Abdominal Cavity Untreated Control NA NA 3_033 112.00 1 Lipoma Scheduled Sacrifice
All Others Unspecified Leg 10000 PPM NA NA 1_038 112.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_021 112.00 1 Leukemia, Lymphocytic Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_035 112.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_048 112.00 1 Leukemia, Granulocytic Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_007 112.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_014 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_019 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_024 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_033 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_042 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_044 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_045 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 2_021 112.00 1 Leukemia, Granulocytic Natural Death
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 2_027 112.00 1 Leukemia, Lymphocytic Natural Death
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 2_034 112.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 2_040 112.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 2_042 112.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 2_010 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 2_013 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 2_033 112.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_007 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_016 112.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_021 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_022 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_043 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_048 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Tail Untreated Control NA NA 3_022 112.00 1 Fibrosarcoma Scheduled Sacrifice
All Others Unspecified Untreated Control NA NA 3_018 112.00 1 Rhabdomyosarcoma Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_048 112.00 1 Fibrosarcoma Natural Death
All Others Unspecified Untreated Control NA NA 3_050 112.00 1 Hemangioma Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 44 NA 3_018 112.00 1 Chromophobe Carcinoma Moribund Sacrifice
Endocrine System Pituitary gland Untreated Control 44 NA 3_023 112.00 1 Chromophobe Carcinoma Scheduled Sacrifice
Endocrine System Pituitary gland 10000 PPM 40 NA 1_043 112.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 39 NA 3_010 112.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Genital System Ovary 10000 PPM 46 NA 1_006 112.00 1 Papillary Adenoma Scheduled Sacrifice
Genital System Ovary 10000 PPM 46 NA 1_011 112.00 1 Granulosa-Cell Tumor Scheduled Sacrifice
Genital System Ovary 10000 PPM 46 NA 1_028 112.00 1 Hemangioma Scheduled Sacrifice
Genital System Uterus 5000 PPM 47 NA 2_007 112.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 10000 PPM 47 NA 1_025 112.00 1 Leiomyosarcoma Scheduled Sacrifice
Genital System Uterus 10000 PPM 47 NA 1_042 112.00 1 Hemangiosarcoma Scheduled Sacrifice
Genital System Uterus 10000 PPM 47 NA 1_047 112.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Hematopoietic System Lymph node Abdominal Lymph Node Untreated Control 38 NA 3_026 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Hematopoietic System Lymph node Lumbar Lymph Node Untreated Control 38 NA 3_030 112.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 10000 PPM 45 NA 1_017 112.00 1 Adenocarcinoma/Squamous Metaplasia, Metastatic Moribund Sacrifice
Hematopoietic System Lymph node Pancreatic Lymph Node 5000 PPM 37 NA 2_029 112.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 50 NA 3_006 112.00 1 Hemangiosarcoma Natural Death
Hematopoietic System Spleen 5000 PPM 46 NA 2_044 112.00 1 Hemangioma Scheduled Sacrifice
Integumentary System Mammary gland 5000 PPM 33 NA 2_029 112.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland 10000 PPM 31 NA 1_017 112.00 1 Adenocarcinoma/Squamous Metaplasia Moribund Sacrifice
Integumentary System Skin Axilla 5000 PPM 46 NA 2_021 112.00 1 Basal-Cell Tumor Natural Death
Respiratory System Lung Untreated Control 50 NA 3_032 112.00 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung 5000 PPM 46 NA 2_018 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_017 112.00 1 Adenocarcinoma/Squamous Metaplasia, Metastatic Moribund Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_038 112.00 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_049 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland Untreated Control 50 NA 3_047 112.00 1 Papillary Adenoma Moribund Sacrifice
Special Senses System Eye Lacrimal Gland 10000 PPM 50 NA 1_009 112.00 1 Papillary Adenoma Scheduled Sacrifice
Urinary System Urinary bladder 10000 PPM NA NA 1_017 112.00 1 Adenocarcinoma/Squamous Metaplasia, Metastatic Moribund Sacrifice