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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Chlordane (analytical grade)
CASRN: ="57-74-9"
Study Number: C00099
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Male
Strain and Species: Osborne Mendel Rats

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 8 NA 1_045 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Alimentary System Liver 400 PPM 44 NA 2_022 113.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 400 PPM 44 NA 2_043 113.00 1 Neoplastic Nodule Scheduled Sacrifice
Alimentary System Pancreas 800 PPM 36 NA 3_054 114.00 1 Fibrous Histiocytoma, Malignant Scheduled Sacrifice
Alimentary System Stomach 800 PPM 39 NA 3_054 114.00 1 Fibrous Histiocytoma, Malignant Scheduled Sacrifice
All Others Unspecified Diaphragm Nos 800 PPM NA NA 3_061 114.00 1 Osteosarcoma Natural Death
All Others Unspecified Multiple Organs Nos 800 PPM NA NA 3_072 114.00 1 Fibrous Histiocytoma, Malignant Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 800 PPM NA NA 3_075 114.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice
All Others Unspecified 400 PPM NA NA 2_027 113.00 1 Lipoma Natural Death
All Others Unspecified 800 PPM NA NA 3_063 114.00 1 Fibrous Histiocytoma, Malignant Moribund Sacrifice
All Others Unspecified 800 PPM NA NA 3_070 114.00 1 Fibrous Histiocytoma, Malignant Moribund Sacrifice
All Others Unspecified 800 PPM NA NA 3_087 114.00 1 Fibrous Histiocytoma, Malignant Moribund Sacrifice
All Others Unspecified 800 PPM NA NA 3_100 114.00 1 Fibrous Histiocytoma, Malignant Scheduled Sacrifice
Endocrine System Adrenal gland 400 PPM 39 NA 2_014 113.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_015 113.00 1 Chromophobe Adenoma Moribund Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_020 113.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_034 113.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_049 113.00 1 Chromophobe Adenoma Moribund Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_012 113.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_022 113.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_024 113.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_029 113.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_030 113.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 400 PPM 34 NA 2_036 113.00 1 Chromophobe Carcinoma Scheduled Sacrifice
Endocrine System Pituitary gland 800 PPM 34 NA 3_053 114.00 1 Chromophobe Adenoma Moribund Sacrifice
Endocrine System Pituitary gland 800 PPM 34 NA 3_057 114.00 1 Chromophobe Adenoma Moribund Sacrifice
Endocrine System Pituitary gland 800 PPM 34 NA 3_058 114.00 1 Chromophobe Adenoma Moribund Sacrifice
Endocrine System Pituitary gland 800 PPM 34 NA 3_070 114.00 1 Chromophobe Adenoma Moribund Sacrifice
Endocrine System Pituitary gland 800 PPM 34 NA 3_051 114.00 1 Carcinoma, Nos Natural Death
Endocrine System Pituitary gland 800 PPM 34 NA 3_080 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 800 PPM 34 NA 3_085 114.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 800 PPM 34 NA 3_100 114.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Thyroid 400 PPM 34 NA 2_024 113.00 1 C-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 400 PPM 34 NA 2_029 113.00 1 C-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 400 PPM 34 NA 2_030 113.00 1 C-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 400 PPM 34 NA 2_036 113.00 1 C-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 400 PPM 34 NA 2_042 113.00 1 C-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 400 PPM 34 NA 2_043 113.00 1 Follicular-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_058 114.00 1 Follicular-Cell Adenoma Moribund Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_067 114.00 1 Follicular-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_074 114.00 1 C-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_074 114.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_080 114.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_083 114.00 1 C-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_089 114.00 1 C-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_090 114.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_092 114.00 1 C-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_094 114.00 1 C-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 800 PPM 31 NA 3_099 114.00 1 Follicular-Cell Carcinoma Scheduled Sacrifice
Genital System Testis 400 PPM 43 NA 2_006 113.00 1 Interstitial-Cell Tumor Scheduled Sacrifice
Genital System Testis 800 PPM 42 NA 3_092 114.00 1 Interstitial-Cell Tumor Scheduled Sacrifice
Hematopoietic System Lymph node Vehicle Control 5 NA 1_045 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen Vehicle Control 8 NA 1_045 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen 800 PPM 38 NA 3_054 114.00 1 Fibrous Histiocytoma, Malignant Scheduled Sacrifice
Integumentary System Mammary gland 800 PPM 1 NA 3_078 114.00 1 Lipoma Moribund Sacrifice
Integumentary System Skin 400 PPM 15 NA 2_032 113.00 1 Carcinoma, Nos Natural Death
Integumentary System Skin 800 PPM 17 NA 3_053 114.00 1 Squamous Cell Carcinoma Moribund Sacrifice
Musculoskeletal System Skeletal muscle 400 PPM NA NA 2_029 113.00 1 Fibrous Histiocytoma, Malignant Scheduled Sacrifice
Musculoskeletal System Skeletal muscle 800 PPM NA NA 3_063 114.00 1 Fibrous Histiocytoma, Malignant Moribund Sacrifice
Musculoskeletal System Skeletal muscle 800 PPM NA NA 3_070 114.00 1 Fibrous Histiocytoma, Malignant Moribund Sacrifice
Nervous System Brain Vehicle Control 8 NA 1_044 113.00 1 Glioma, Nos Natural Death
Respiratory System Lung 400 PPM 43 NA 2_009 113.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 800 PPM 39 NA 3_067 114.00 1 Fibrous Histiocytoma, Malignant Scheduled Sacrifice
Urinary System Kidney Vehicle Control 8 NA 1_045 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Urinary System Kidney Vehicle Control 8 NA 1_047 113.00 1 Tubular-Cell Adenoma Scheduled Sacrifice
Urinary System Kidney 400 PPM 43 NA 2_002 113.00 1 Mixed Tumor, Malignant Moribund Sacrifice
Urinary System Kidney 400 PPM 43 NA 2_007 113.00 1 Mixed Tumor, Malignant Natural Death
Urinary System Kidney 400 PPM 43 NA 2_033 113.00 1 Mixed Tumor, Malignant Natural Death
Urinary System Kidney 400 PPM 43 NA 2_018 113.00 1 Mixed Tumor, Malignant Scheduled Sacrifice
Urinary System Kidney 800 PPM 42 NA 3_070 114.00 1 Fibrous Histiocytoma, Malignant Moribund Sacrifice
Urinary System Urinary bladder 400 PPM NA NA 2_029 113.00 1 Fibrous Histiocytoma, Malignant Scheduled Sacrifice