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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Parathion
CASRN: ="56-38-2"
Study Number: C00226
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Female
Strain and Species: Osborne Mendel Rats

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Bile Duct Vehicle Control 10 NA 1_297 120.00 1 Bile Duct Adenoma Scheduled Sacrifice
Alimentary System Liver 20 PPM 49 NA 2_116 120.00 1 Neoplastic Nodule Scheduled Sacrifice
Alimentary System Liver 40 PPM 48 NA 3_168 120.00 1 Neoplastic Nodule Moribund Sacrifice
Alimentary System Liver 40 PPM 48 NA 3_173 120.00 1 Neoplastic Nodule Scheduled Sacrifice
Alimentary System Liver 40 PPM 48 NA 3_193 120.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Pancreas Islets Vehicle Control 10 NA 1_293 120.00 1 Islet-Cell Adenoma Scheduled Sacrifice
Alimentary System Pancreas Islets 20 PPM 48 NA 2_105 120.00 1 Islet-Cell Carcinoma Moribund Sacrifice
Alimentary System Pancreas Islets 40 PPM 49 NA 3_151 120.00 1 Islet-Cell Adenoma Natural Death
All Others Unspecified Multiple Organs Nos 20 PPM NA NA 2_108 120.00 1 Fibrous Histiocytoma, Malignant Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 40 PPM NA NA 3_190 120.00 1 Leukemia, Lymphocytic Natural Death
All Others Unspecified 40 PPM NA NA 3_177 120.00 1 C-Cell Carcinoma, Metastatic Moribund Sacrifice
Endocrine System Adrenal gland Vehicle Control 10 NA 1_298 120.00 1 Cortical Adenoma Moribund Sacrifice
Endocrine System Adrenal gland Vehicle Control 10 NA 1_291 120.00 1 Pheochromocytoma, Malignant Scheduled Sacrifice
Endocrine System Adrenal gland 20 PPM 47 NA 2_102 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 20 PPM 47 NA 2_116 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 20 PPM 47 NA 2_119 120.00 1 Cortical Carcinoma Scheduled Sacrifice
Endocrine System Adrenal gland 20 PPM 47 NA 2_129 120.00 1 Cortical Carcinoma Scheduled Sacrifice
Endocrine System Adrenal gland 20 PPM 47 NA 2_135 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 20 PPM 47 NA 2_149 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_160 120.00 1 Cortical Carcinoma Moribund Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_166 120.00 1 Cortical Adenoma Moribund Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_177 120.00 1 C-Cell Carcinoma, Metastatic Moribund Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_155 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_163 120.00 1 Cortical Carcinoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_169 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_179 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_181 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_185 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_186 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_189 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_192 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_193 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 40 PPM 42 NA 3_195 120.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland Vehicle Control 8 NA 1_295 120.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland Vehicle Control 8 NA 1_297 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 20 PPM 38 NA 2_123 120.00 1 Adenoma, Nos Natural Death
Endocrine System Pituitary gland 20 PPM 38 NA 2_146 120.00 1 Adenoma, Nos Natural Death
Endocrine System Pituitary gland 20 PPM 38 NA 2_103 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 20 PPM 38 NA 2_111 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 20 PPM 38 NA 2_116 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 20 PPM 38 NA 2_131 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 20 PPM 38 NA 2_136 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 20 PPM 38 NA 2_137 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 20 PPM 38 NA 2_139 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 20 PPM 38 NA 2_147 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 20 PPM 38 NA 2_149 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_168 120.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_171 120.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_199 120.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_155 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_161 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_163 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_169 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_170 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_172 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_186 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_188 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_194 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 40 PPM 39 NA 3_200 120.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Thyroid Vehicle Control 10 NA 1_298 120.00 1 C-Cell Carcinoma Moribund Sacrifice
Endocrine System Thyroid Vehicle Control 10 NA 1_292 120.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid Vehicle Control 10 NA 1_296 120.00 1 C-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 20 PPM 45 NA 2_108 120.00 1 Follicular-Cell Adenoma Moribund Sacrifice
Endocrine System Thyroid 20 PPM 45 NA 2_113 120.00 1 Follicular-Cell Adenoma Moribund Sacrifice
Endocrine System Thyroid 20 PPM 45 NA 2_123 120.00 1 C-Cell Carcinoma Natural Death
Endocrine System Thyroid 20 PPM 45 NA 2_101 120.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 20 PPM 45 NA 2_128 120.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 20 PPM 45 NA 2_138 120.00 1 C-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 40 PPM 43 NA 3_177 120.00 1 C-Cell Carcinoma Moribund Sacrifice
Endocrine System Thyroid 40 PPM 43 NA 3_169 120.00 1 C-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 40 PPM 43 NA 3_181 120.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 40 PPM 43 NA 3_196 120.00 1 C-Cell Carcinoma Scheduled Sacrifice
General Body System Peritoneum 20 PPM NA NA 2_106 120.00 1 Fibrous Histiocytoma, Malignant Scheduled Sacrifice
Genital System Ovary 20 PPM 45 NA 2_127 120.00 1 Thecoma Moribund Sacrifice
Genital System Ovary 20 PPM 45 NA 2_123 120.00 1 Thecoma Natural Death
Genital System Ovary 40 PPM 45 NA 3_187 120.00 1 Cystadenocarcinoma, Nos Scheduled Sacrifice
Genital System Uterus Vehicle Control 10 NA 1_298 120.00 1 Endometrial Stromal Polyp Moribund Sacrifice
Genital System Uterus 20 PPM 49 NA 2_114 120.00 1 Adenocarcinoma In Adenomatous Polyp Scheduled Sacrifice
Genital System Uterus 20 PPM 49 NA 2_114 120.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 20 PPM 49 NA 2_130 120.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 20 PPM 49 NA 2_136 120.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 20 PPM 49 NA 2_147 120.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 40 PPM 45 NA 3_153 120.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 40 PPM 45 NA 3_159 120.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 40 PPM 45 NA 3_169 120.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 40 PPM 45 NA 3_188 120.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 40 PPM 45 NA 3_193 120.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Hematopoietic System Lymph node Cervical Lymph Node Nos Vehicle Control 10 NA 1_298 120.00 1 C-Cell Carcinoma, Metastatic Moribund Sacrifice
Hematopoietic System Lymph node Vehicle Control 10 NA 1_300 120.00 1 Hemangioma Scheduled Sacrifice
Hematopoietic System Lymph node 20 PPM 41 NA 2_104 120.00 1 Hemangioma Scheduled Sacrifice
Hematopoietic System Spleen 40 PPM 49 NA 3_187 120.00 1 Sarcoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland Vehicle Control 3 NA 1_299 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland Vehicle Control 3 NA 1_297 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland Vehicle Control 3 NA 1_300 120.00 1 Adenoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_105 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_107 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_113 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_120 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_124 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_126 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_127 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_144 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_150 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_146 120.00 1 Adenoma, Nos Natural Death
Integumentary System Mammary gland 20 PPM 18 NA 2_102 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_104 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_106 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_116 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_116 120.00 1 Fibroma Scheduled Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_134 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_136 120.00 1 Papillary Adenocarcinoma Scheduled Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_142 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 20 PPM 18 NA 2_149 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 40 PPM 8 NA 3_171 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 40 PPM 8 NA 3_199 120.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland 40 PPM 8 NA 3_199 120.00 1 Fibroma Moribund Sacrifice
Integumentary System Mammary gland 40 PPM 8 NA 3_153 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 40 PPM 8 NA 3_155 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 40 PPM 8 NA 3_179 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 40 PPM 8 NA 3_184 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 40 PPM 8 NA 3_185 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 40 PPM 8 NA 3_194 120.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Skin 40 PPM 48 NA 3_162 120.00 1 Neoplasm, Malignant, Nos Moribund Sacrifice
Respiratory System Lung Vehicle Control 10 NA 1_298 120.00 1 C-Cell Carcinoma, Metastatic Moribund Sacrifice
Respiratory System Lung 40 PPM 47 NA 3_177 120.00 1 C-Cell Carcinoma, Metastatic Moribund Sacrifice
Respiratory System Lung 40 PPM 47 NA 3_188 120.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice