Alimentary System |
Liver |
Hepatocyte |
0.1 MG/KG |
10 |
63 |
72 |
92 |
1 |
Vacuolization Cytoplasmic |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
Hepatocyte |
0.1 MG/KG |
10 |
63 |
73 |
92 |
1 |
Vacuolization Cytoplasmic |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
Hepatocyte |
1 MG/KG |
10 |
65 |
83 |
92 |
1 |
Vacuolization Cytoplasmic |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
Hepatocyte |
1 MG/KG |
10 |
65 |
84 |
92 |
1 |
Vacuolization Cytoplasmic |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
Hepatocyte |
1 MG/KG |
10 |
65 |
85 |
92 |
1 |
Vacuolization Cytoplasmic |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
Hepatocyte |
1 MG/KG |
10 |
66 |
86 |
92 |
1 |
Vacuolization Cytoplasmic |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Hepatocyte |
1 MG/KG |
10 |
66 |
88 |
92 |
1 |
Vacuolization Cytoplasmic |
Moderate |
Terminal Sacrifice |
Alimentary System |
Liver |
Hepatocyte |
3 MG/KG |
10 |
68 |
97 |
92 |
1 |
Vacuolization Cytoplasmic |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Hepatocyte |
10 MG/KG |
10 |
70 |
110 |
92 |
1 |
Vacuolization Cytoplasmic |
Minimal |
Accidentally Killed |
Alimentary System |
Liver |
Hepatocyte |
30 MG/KG |
10 |
72 |
116 |
92 |
1 |
Vacuolization Cytoplasmic |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
Hepatocyte |
30 MG/KG |
10 |
72 |
117 |
92 |
1 |
Vacuolization Cytoplasmic |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
1 MG/KG |
10 |
66 |
90 |
92 |
1 |
Hyperplasia |
Minimal |
Accidentally Killed |
Alimentary System |
Stomach |
Forestomach, Epithelium |
1 MG/KG |
10 |
65 |
82 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
1 MG/KG |
10 |
65 |
83 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
1 MG/KG |
10 |
65 |
85 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
1 MG/KG |
10 |
66 |
87 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
1 MG/KG |
10 |
66 |
88 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
1 MG/KG |
10 |
66 |
89 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
3 MG/KG |
10 |
67 |
92 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
3 MG/KG |
10 |
67 |
93 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
3 MG/KG |
10 |
67 |
94 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
3 MG/KG |
10 |
68 |
96 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
3 MG/KG |
10 |
68 |
97 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
3 MG/KG |
10 |
68 |
98 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
3 MG/KG |
10 |
68 |
99 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
10 MG/KG |
10 |
69 |
104 |
92 |
1 |
Hyperplasia |
Mild |
Accidentally Killed |
Alimentary System |
Stomach |
Forestomach, Epithelium |
10 MG/KG |
10 |
69 |
101 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
10 MG/KG |
10 |
69 |
102 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
10 MG/KG |
10 |
69 |
103 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
10 MG/KG |
10 |
70 |
106 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
30 MG/KG |
10 |
72 |
120 |
92 |
1 |
Hyperplasia |
Mild |
Accidentally Killed |
Alimentary System |
Stomach |
Forestomach, Epithelium |
30 MG/KG |
10 |
71 |
113 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
30 MG/KG |
10 |
71 |
114 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
30 MG/KG |
10 |
71 |
115 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
30 MG/KG |
10 |
72 |
116 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
30 MG/KG |
10 |
72 |
118 |
92 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Stomach |
Forestomach, Epithelium |
30 MG/KG |
10 |
72 |
119 |
92 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
Vehicle Control |
10 |
61 |
63 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
Vehicle Control |
10 |
61 |
65 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
Vehicle Control |
10 |
62 |
67 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
Vehicle Control |
10 |
62 |
68 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
Vehicle Control |
10 |
62 |
70 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
0.1 MG/KG |
10 |
63 |
71 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
0.1 MG/KG |
10 |
63 |
73 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
0.1 MG/KG |
10 |
63 |
74 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
0.1 MG/KG |
10 |
63 |
75 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
0.1 MG/KG |
10 |
64 |
76 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
0.1 MG/KG |
10 |
64 |
77 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
0.1 MG/KG |
10 |
64 |
78 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
0.1 MG/KG |
10 |
64 |
79 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
0.1 MG/KG |
10 |
64 |
80 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
66 |
90 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Accidentally Killed |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
65 |
81 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
65 |
82 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
65 |
83 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
65 |
84 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
65 |
85 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
66 |
86 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
66 |
87 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
66 |
88 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
1 MG/KG |
10 |
66 |
89 |
92 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
67 |
95 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Accidentally Killed |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
67 |
91 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
67 |
92 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
67 |
93 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
67 |
94 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
68 |
100 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
68 |
96 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
68 |
97 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
68 |
98 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
3 MG/KG |
10 |
68 |
99 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
69 |
104 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Accidentally Killed |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
70 |
110 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Accidentally Killed |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
69 |
101 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
69 |
102 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
69 |
103 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
69 |
105 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
70 |
106 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
70 |
107 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
70 |
108 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
10 MG/KG |
10 |
70 |
109 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
72 |
120 |
92 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Accidentally Killed |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
71 |
111 |
92 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
71 |
112 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
71 |
113 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
71 |
114 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
71 |
115 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
72 |
116 |
92 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
72 |
117 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
72 |
118 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
Red Pulp |
30 MG/KG |
10 |
72 |
119 |
92 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
30 MG/KG |
10 |
71 |
114 |
92 |
1 |
Hyperplasia |
Minimal, Focal |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
30 MG/KG |
10 |
72 |
117 |
92 |
1 |
Hyperplasia |
Mild, Focal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
10 |
62 |
67 |
92 |
1 |
Inflammation |
Minimal, Focal, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
30 MG/KG |
10 |
71 |
114 |
92 |
1 |
Inflammation |
Mild, Focal, Chronic |
Terminal Sacrifice |