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Short-Term Individual Animal Non Neoplastic Diagnosis
Study Information:
Chemical Name: | 5-(Hydroxymethyl)-2-furfural |
CASRN: | ="67-47-0" |
Study Number: | C95011 |
Exposure Route: | GAVAGE |
TDMS Number: | 9501104 |
Sex: | Female |
Strain and Species: | B6C3F1 Mice |
Female Individual Animal Non Neoplastic Diagnoses
System |
Organ |
Site |
Treatment Group |
Number Examined |
Cage Number |
Animal Number |
Days on Study |
Lesion Found |
Lesion Name |
Lesion Qualifier |
Removal Reason |
Alimentary System |
Esophagus |
Muscularis |
Vehicle Control |
10 |
302 |
309 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Esophagus |
Muscularis |
Vehicle Control |
10 |
302 |
310 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Esophagus |
Muscularis |
375 MG/KG |
1 |
309 |
343 |
77 |
1 |
Inflammation |
Minimal |
Natural Death |
Alimentary System |
Esophagus |
Muscularis |
750 MG/KG |
10 |
312 |
359 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
301 |
301 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
301 |
303 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
301 |
304 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
301 |
305 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
302 |
307 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
302 |
309 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
750 MG/KG |
10 |
311 |
351 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
750 MG/KG |
10 |
311 |
353 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
750 MG/KG |
10 |
311 |
354 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
750 MG/KG |
10 |
311 |
355 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
750 MG/KG |
10 |
312 |
358 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
|
Vehicle Control |
10 |
302 |
307 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
375 MG/KG |
1 |
309 |
343 |
77 |
1 |
Atrophy |
Mild |
Natural Death |
Hematopoietic System |
Lymph Node |
Mesenteric |
375 MG/KG |
1 |
309 |
343 |
77 |
1 |
Atrophy |
Mild |
Natural Death |
Hematopoietic System |
Spleen |
|
375 MG/KG |
1 |
309 |
343 |
77 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Natural Death |
Hematopoietic System |
Spleen |
|
750 MG/KG |
10 |
311 |
351 |
94 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
375 MG/KG |
1 |
309 |
343 |
77 |
1 |
Atrophy |
Marked |
Natural Death |
Respiratory System |
Lung |
|
Vehicle Control |
10 |
301 |
303 |
94 |
1 |
Inflammation |
Minimal |
Terminal Sacrifice |
Respiratory System |
Lung |
|
375 MG/KG |
1 |
309 |
343 |
77 |
1 |
Inflammation |
Minimal |
Natural Death |
Respiratory System |
Nose |
Olfactory Epi |
750 MG/KG |
10 |
312 |
359 |
94 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
750 MG/KG |
10 |
312 |
357 |
94 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |