Alimentary System |
Esophagus |
|
6 MG/KG |
16 |
22 |
6 |
561 |
1 |
Foreign Body |
Moderate |
Dead |
Alimentary System |
Esophagus |
|
Vehicle Control |
50 |
8 |
40 |
531 |
1 |
Inflammation |
Marked, Necrotizing |
Dead |
Alimentary System |
Intestine Large |
Colon |
Vehicle Control |
50 |
6 |
29 |
711 |
1 |
Parasite Metazoan |
|
Moribund |
Alimentary System |
Intestine Large |
Colon |
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Parasite Metazoan |
|
Moribund |
Alimentary System |
Intestine Large |
Colon |
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Parasite Metazoan |
|
Moribund |
Alimentary System |
Intestine Large |
Colon |
12 MG/KG |
50 |
45 |
23 |
655 |
1 |
Parasite Metazoan |
|
Moribund |
Alimentary System |
Intestine Large |
Colon |
12 MG/KG |
50 |
41 |
5 |
733 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Colon |
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum |
6 MG/KG |
16 |
25 |
21 |
408 |
1 |
Inflammation |
Marked, Chronic Active |
Dead |
Alimentary System |
Intestine Large |
Rectum |
Vehicle Control |
50 |
10 |
50 |
733 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum |
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum |
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum |
6 MG/KG |
16 |
21 |
2 |
549 |
1 |
Parasite Metazoan |
|
Moribund |
Alimentary System |
Intestine Large |
Rectum |
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Parasite Metazoan |
|
Moribund |
Alimentary System |
Intestine Large |
Rectum |
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Parasite Metazoan |
|
Moribund |
Alimentary System |
Intestine Large |
Rectum |
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Intestine Large |
Rectum |
12 MG/KG |
50 |
50 |
50 |
731 |
1 |
Parasite Metazoan |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
5 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
8 |
37 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
25 |
22 |
731 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
26 |
26 |
726 |
1 |
Basophilic Focus |
|
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
21 |
4 |
732 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
24 |
16 |
732 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
24 |
20 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
25 |
24 |
733 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
26 |
27 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
27 |
35 |
733 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
28 |
37 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
29 |
42 |
732 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
29 |
43 |
733 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
30 |
47 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
30 |
49 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
30 |
50 |
733 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
48 |
40 |
733 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Basophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
23 |
15 |
515 |
1 |
Clear Cell Focus |
|
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
46 |
29 |
732 |
Multiple |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
48 |
40 |
733 |
1 |
Clear Cell Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Degeneration |
Mild, Cystic |
Dead |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
14 |
624 |
1 |
Degeneration |
Minimal, Cystic |
Dead |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Degeneration |
Mild, Cystic |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Degeneration |
Minimal, Cystic |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Degeneration |
Moderate, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
5 |
731 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
9 |
43 |
731 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
23 |
11 |
600 |
1 |
Degeneration |
Mild, Cystic |
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
23 |
14 |
641 |
1 |
Degeneration |
Minimal, Cystic |
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
21 |
5 |
732 |
1 |
Degeneration |
Moderate, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
24 |
20 |
731 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
25 |
24 |
733 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
26 |
27 |
731 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
28 |
37 |
731 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
30 |
46 |
732 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Degeneration |
Minimal, Cystic |
Dead |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Degeneration |
Minimal, Cystic |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Degeneration |
Mild, Cystic |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Degeneration |
Mild, Cystic |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Degeneration |
Minimal, Cystic |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Degeneration |
Marked, Cystic |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Degeneration |
Minimal, Cystic |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Degeneration |
Mild, Cystic |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
41 |
5 |
733 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Degeneration |
Moderate, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Degeneration |
Minimal, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Degeneration |
Marked, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
50 |
47 |
732 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
50 |
50 |
731 |
1 |
Degeneration |
Mild, Cystic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Eosinophilic Focus |
|
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
15 |
515 |
1 |
Fatty Change |
Marked |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Fatty Change |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Hepatodiaphragmatic Nodule |
|
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Hepatodiaphragmatic Nodule |
|
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
25 |
21 |
408 |
1 |
Hepatodiaphragmatic Nodule |
|
Dead |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
46 |
27 |
604 |
1 |
Hepatodiaphragmatic Nodule |
|
Dead |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
15 |
515 |
1 |
Inflammation |
Marked, Necrotizing |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
4 |
20 |
410 |
1 |
Inflammation |
Mild, Chronic |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
1 |
5 |
731 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
6 |
26 |
731 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
23 |
11 |
600 |
1 |
Inflammation |
Minimal, Chronic |
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
26 |
26 |
726 |
1 |
Inflammation |
Minimal, Chronic |
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
27 |
34 |
379 |
1 |
Inflammation |
Minimal, Chronic |
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
24 |
16 |
732 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
25 |
23 |
732 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
29 |
43 |
733 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
30 |
47 |
731 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
45 |
23 |
655 |
1 |
Inflammation |
Minimal, Chronic |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
41 |
3 |
731 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
24 |
18 |
690 |
1 |
Leukocytosis |
|
Dead |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Mineralization |
Mild |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
48 |
39 |
487 |
1 |
Mineralization |
Mild |
Moribund |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Necrosis |
Mild, Coagulative |
Dead |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Necrosis |
Marked, Coagulative |
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
25 |
21 |
408 |
1 |
Necrosis |
Moderate, Coagulative |
Dead |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
29 |
45 |
492 |
1 |
Necrosis |
Moderate, Coagulative |
Dead |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Necrosis |
Moderate, Coagulative |
Dead |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Necrosis |
Marked, Coagulative |
Dead |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
46 |
27 |
604 |
1 |
Necrosis |
Moderate, Coagulative |
Dead |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Necrosis |
Moderate, Coagulative |
Moribund |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Necrosis |
Mild, Coagulative |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
50 |
10 |
50 |
733 |
1 |
Vacuolization Cytoplasmic |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
27 |
31 |
641 |
1 |
Vacuolization Cytoplasmic |
Moderate |
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
27 |
33 |
596 |
1 |
Vacuolization Cytoplasmic |
Moderate |
Moribund |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
27 |
35 |
733 |
1 |
Vacuolization Cytoplasmic |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
6 MG/KG |
50 |
29 |
42 |
732 |
1 |
Vacuolization Cytoplasmic |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
|
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Vacuolization Cytoplasmic |
Moderate |
Moribund |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
3 |
14 |
624 |
1 |
Atrophy |
Mild |
Dead |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Atrophy |
Mild |
Dead |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
8 |
40 |
531 |
1 |
Atrophy |
Minimal |
Dead |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Atrophy |
Minimal |
Moribund |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Atrophy |
Mild |
Moribund |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
5 |
22 |
674 |
1 |
Atrophy |
Marked |
Moribund |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
6 |
29 |
711 |
1 |
Atrophy |
Minimal |
Moribund |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
9 |
45 |
676 |
1 |
Atrophy |
Mild |
Moribund |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
2 |
8 |
733 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
6 MG/KG |
19 |
26 |
29 |
608 |
1 |
Atrophy |
Minimal |
Dead |
Alimentary System |
Pancreas |
Acinus |
6 MG/KG |
19 |
27 |
32 |
600 |
1 |
Atrophy |
Minimal |
Dead |
Alimentary System |
Pancreas |
Acinus |
6 MG/KG |
19 |
29 |
44 |
596 |
1 |
Atrophy |
Moderate |
Dead |
Alimentary System |
Pancreas |
Acinus |
6 MG/KG |
19 |
21 |
2 |
549 |
1 |
Atrophy |
Mild |
Moribund |
Alimentary System |
Pancreas |
Acinus |
6 MG/KG |
19 |
22 |
8 |
575 |
1 |
Atrophy |
Mild |
Moribund |
Alimentary System |
Pancreas |
Acinus |
6 MG/KG |
19 |
23 |
11 |
600 |
1 |
Atrophy |
Minimal |
Moribund |
Alimentary System |
Pancreas |
Acinus |
6 MG/KG |
19 |
23 |
13 |
515 |
1 |
Atrophy |
Mild |
Moribund |
Alimentary System |
Pancreas |
Acinus |
6 MG/KG |
19 |
23 |
15 |
515 |
1 |
Atrophy |
Minimal |
Moribund |
Alimentary System |
Pancreas |
Acinus |
6 MG/KG |
19 |
22 |
10 |
732 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Atrophy |
Mild |
Dead |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Atrophy |
Mild |
Dead |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
41 |
3 |
731 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
42 |
9 |
733 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Atrophy |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Artery |
6 MG/KG |
19 |
23 |
12 |
722 |
1 |
Inflammation |
Marked, Proliferative |
Moribund |
Alimentary System |
Pancreas |
Artery |
6 MG/KG |
19 |
22 |
10 |
732 |
1 |
Inflammation |
Moderate, Proliferative |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Artery |
6 MG/KG |
19 |
25 |
23 |
732 |
1 |
Inflammation |
Moderate, Proliferative |
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
6 MG/KG |
19 |
22 |
10 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Alimentary System |
Pancreas |
|
Vehicle Control |
50 |
6 |
27 |
422 |
1 |
Inflammation |
Mild, Chronic |
Dead |
Alimentary System |
Pancreas |
|
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Pigmentation |
Mild, Hemosiderin |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Alimentary System |
Stomach |
Epithelium, Forestomach |
6 MG/KG |
16 |
27 |
33 |
596 |
1 |
Hyperplasia |
Moderate |
Moribund |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Alimentary System |
Stomach |
Forestomach |
Vehicle Control |
50 |
3 |
15 |
515 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Alimentary System |
Stomach |
Forestomach |
6 MG/KG |
16 |
22 |
7 |
421 |
1 |
Inflammation |
Marked, Chronic Active |
Moribund |
Alimentary System |
Stomach |
Forestomach |
6 MG/KG |
16 |
27 |
33 |
596 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Alimentary System |
Stomach |
Forestomach |
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Alimentary System |
Stomach |
Forestomach |
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Mineralization |
Mild |
Moribund |
Alimentary System |
Stomach |
Glandular |
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Mineralization |
Mild |
Moribund |
Alimentary System |
Stomach |
Glandular |
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Mineralization |
Mild |
Moribund |
Alimentary System |
Stomach |
Glandular |
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Mineralization |
Moderate |
Moribund |
Alimentary System |
Stomach |
Glandular |
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Mineralization |
Moderate |
Moribund |
Alimentary System |
Stomach |
Glandular |
Vehicle Control |
50 |
3 |
15 |
515 |
1 |
Necrosis |
Marked, Coagulative |
Moribund |
Alimentary System |
Tooth |
|
Vehicle Control |
49 |
10 |
49 |
627 |
1 |
Inflammation |
Mild, Suppurative |
Moribund |
Cardiovascular System |
Blood Vessel |
Aorta |
12 MG/KG |
48 |
50 |
48 |
654 |
1 |
Mineralization |
Moderate |
Moribund |
Cardiovascular System |
Blood Vessel |
Intima, Mesent Artery |
Vehicle Control |
49 |
9 |
45 |
676 |
1 |
Proliferation |
Moderate |
Moribund |
Cardiovascular System |
Blood Vessel |
Mesent Artery |
Vehicle Control |
49 |
8 |
38 |
719 |
1 |
Mineralization |
Mild |
Moribund |
Cardiovascular System |
Blood Vessel |
Pulmn Artery |
12 MG/KG |
48 |
50 |
48 |
654 |
1 |
Mineralization |
Moderate |
Moribund |
Cardiovascular System |
Heart |
Atrium |
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Thrombosis |
|
Moribund |
Cardiovascular System |
Heart |
Atrium |
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Thrombosis |
|
Terminal Sacrifice |
Cardiovascular System |
Heart |
Atrium |
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Thrombosis |
|
Terminal Sacrifice |
Cardiovascular System |
Heart |
Atrium |
6 MG/KG |
21 |
25 |
21 |
408 |
1 |
Thrombosis |
|
Dead |
Cardiovascular System |
Heart |
Atrium |
6 MG/KG |
21 |
29 |
45 |
492 |
1 |
Thrombosis |
|
Dead |
Cardiovascular System |
Heart |
Atrium |
6 MG/KG |
21 |
22 |
9 |
695 |
1 |
Thrombosis |
|
Moribund |
Cardiovascular System |
Heart |
Atrium |
6 MG/KG |
21 |
24 |
19 |
676 |
1 |
Thrombosis |
|
Moribund |
Cardiovascular System |
Heart |
Atrium |
6 MG/KG |
21 |
27 |
31 |
641 |
1 |
Thrombosis |
|
Moribund |
Cardiovascular System |
Heart |
Atrium |
6 MG/KG |
21 |
30 |
48 |
697 |
1 |
Thrombosis |
|
Moribund |
Cardiovascular System |
Heart |
Atrium |
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Thrombosis |
|
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
3 |
11 |
589 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
3 |
14 |
624 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
4 |
19 |
593 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
6 |
27 |
422 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
40 |
531 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
4 |
708 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
47 |
688 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
3 |
15 |
515 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
4 |
18 |
655 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
4 |
20 |
410 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
5 |
21 |
695 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
5 |
22 |
674 |
1 |
Cardiomyopathy |
Minimal, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
6 |
29 |
711 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
9 |
45 |
676 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
2 |
733 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
3 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
1 |
5 |
731 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
50 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
2 |
10 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
2 |
8 |
733 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
3 |
13 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
5 |
23 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
5 |
25 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
6 |
26 |
731 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
6 |
30 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
33 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
37 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
9 |
43 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
22 |
6 |
561 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
25 |
21 |
408 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Dead |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
26 |
29 |
608 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
27 |
32 |
600 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
29 |
44 |
596 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
29 |
45 |
492 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
21 |
2 |
549 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
21 |
3 |
555 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
22 |
9 |
695 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
23 |
11 |
600 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
23 |
13 |
515 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
23 |
15 |
515 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
27 |
31 |
641 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
27 |
33 |
596 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
28 |
40 |
509 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
6 MG/KG |
21 |
29 |
42 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
44 |
17 |
367 |
1 |
Cardiomyopathy |
Mild, Chronic |
Dead |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Dead |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
46 |
27 |
604 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Dead |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
43 |
13 |
695 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
43 |
14 |
726 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
45 |
22 |
425 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
45 |
23 |
655 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
48 |
37 |
708 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
50 |
49 |
695 |
1 |
Cardiomyopathy |
Mild, Chronic |
Moribund |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
41 |
3 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
42 |
9 |
733 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
45 |
21 |
732 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
47 |
35 |
732 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
48 |
38 |
732 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
48 |
40 |
733 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
49 |
42 |
733 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Cardiomyopathy |
Mild, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
50 |
47 |
732 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
12 MG/KG |
50 |
50 |
50 |
731 |
1 |
Cardiomyopathy |
Moderate, Chronic |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Infarct |
Marked |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Mineralization |
Moderate |
Moribund |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Accessory Adrenal Cortical Nodule |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
4 |
19 |
593 |
1 |
Degeneration |
Minimal, Fatty |
Dead |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Degeneration |
Minimal, Fatty |
Dead |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Degeneration |
Moderate, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
3 |
15 |
515 |
1 |
Degeneration |
Moderate, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
4 |
18 |
655 |
1 |
Degeneration |
Minimal, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Degeneration |
Minimal, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Degeneration |
Mild, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
21 |
2 |
549 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
23 |
14 |
641 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
24 |
19 |
676 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
25 |
25 |
677 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
26 |
26 |
726 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
27 |
33 |
596 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
28 |
39 |
684 |
1 |
Degeneration |
Minimal, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
21 |
1 |
733 |
1 |
Degeneration |
Mild, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
25 |
23 |
732 |
1 |
Degeneration |
Minimal, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
25 |
24 |
733 |
1 |
Degeneration |
Mild, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
27 |
35 |
733 |
1 |
Degeneration |
Minimal, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
29 |
43 |
733 |
1 |
Degeneration |
Mild, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Degeneration |
Minimal, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
43 |
13 |
695 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Degeneration |
Mild, Fatty |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Degeneration |
Mild, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Degeneration |
Minimal, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Degeneration |
Minimal, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Degeneration |
Minimal, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
50 |
47 |
732 |
1 |
Degeneration |
Moderate, Fatty |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
1 |
2 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
5 |
25 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
21 |
2 |
549 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
23 |
13 |
515 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
24 |
16 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
25 |
23 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
25 |
24 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
27 |
35 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
29 |
41 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
29 |
42 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
29 |
43 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
30 |
47 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
43 |
14 |
726 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
41 |
5 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
47 |
35 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
48 |
38 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Hypertrophy |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
24 |
19 |
676 |
1 |
Hypertrophy |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
21 |
1 |
733 |
1 |
Hypertrophy |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Hypertrophy |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
41 |
5 |
733 |
1 |
Hypertrophy |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Hypertrophy |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Hypertrophy |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
6 MG/KG |
50 |
30 |
47 |
731 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Cortex |
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Necrosis |
Mild, Coagulative |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Angiectasis |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
21 |
1 |
733 |
1 |
Atypia Cellular |
|
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Hyperplasia |
Mild |
Dead |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
10 |
47 |
688 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
1 |
3 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
1 |
5 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
6 |
30 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
21 |
3 |
555 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
23 |
11 |
600 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
23 |
12 |
722 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
23 |
14 |
641 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
24 |
19 |
676 |
1 |
Hyperplasia |
Moderate |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
25 |
22 |
731 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
25 |
25 |
677 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
26 |
26 |
726 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
26 |
30 |
708 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
27 |
31 |
641 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
30 |
48 |
697 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
21 |
1 |
733 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
24 |
16 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
24 |
20 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
25 |
23 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
27 |
35 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
28 |
37 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
28 |
38 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
29 |
41 |
732 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
29 |
42 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
29 |
43 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
30 |
46 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
30 |
49 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
6 MG/KG |
50 |
30 |
50 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
50 |
49 |
695 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
41 |
5 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
42 |
9 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
47 |
35 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
48 |
40 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
50 |
47 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Necrosis |
Moderate, Coagulative |
Dead |
Endocrine System |
Adrenal Gland |
Medulla |
12 MG/KG |
50 |
46 |
27 |
604 |
1 |
Necrosis |
Moderate, Coagulative |
Dead |
Endocrine System |
Islets |
Pancreatic |
6 MG/KG |
16 |
23 |
15 |
515 |
1 |
Vacuolization Cytoplasmic |
Mild |
Moribund |
Endocrine System |
Parathyroid Gland |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Hyperplasia |
Moderate |
Moribund |
Endocrine System |
Parathyroid Gland |
|
6 MG/KG |
16 |
23 |
11 |
600 |
1 |
Hyperplasia |
Moderate |
Moribund |
Endocrine System |
Parathyroid Gland |
|
6 MG/KG |
16 |
27 |
33 |
596 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Parathyroid Gland |
|
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Hyperplasia |
Moderate |
Moribund |
Endocrine System |
Parathyroid Gland |
|
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Hyperplasia |
Marked |
Moribund |
Endocrine System |
Parathyroid Gland |
|
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Hyperplasia |
Marked |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
10 |
47 |
688 |
1 |
Cyst |
|
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
4 |
18 |
655 |
1 |
Cyst |
|
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
5 |
23 |
733 |
1 |
Cyst |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
6 |
30 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
6 MG/KG |
27 |
22 |
9 |
695 |
1 |
Cyst |
|
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Cyst |
|
Dead |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Cyst |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Hyperplasia |
Minimal |
Dead |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
3 |
14 |
624 |
1 |
Hyperplasia |
Mild |
Dead |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
8 |
40 |
531 |
1 |
Hyperplasia |
Mild |
Dead |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
1 |
4 |
708 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
10 |
47 |
688 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
1 |
2 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
1 |
3 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
5 |
25 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
7 |
33 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
6 MG/KG |
27 |
25 |
22 |
731 |
1 |
Hyperplasia |
Moderate |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
6 MG/KG |
27 |
24 |
20 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
6 MG/KG |
27 |
30 |
50 |
733 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Hyperplasia |
Minimal |
Dead |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
43 |
14 |
726 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
41 |
5 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
42 |
9 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
47 |
35 |
732 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
50 |
9 |
43 |
731 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Intermed |
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Angiectasis |
Mild |
Moribund |
Endocrine System |
Pituitary Gland |
Pars Intermed |
Vehicle Control |
50 |
3 |
13 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Intermed |
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Intermed |
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Cyst |
|
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Intermed |
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Cyst |
|
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
4 |
20 |
410 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
5 |
21 |
695 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
5 |
22 |
674 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
1 |
2 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
6 MG/KG |
20 |
21 |
2 |
549 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
6 MG/KG |
20 |
21 |
3 |
555 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
6 MG/KG |
20 |
23 |
13 |
515 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
6 MG/KG |
20 |
27 |
34 |
379 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
6 MG/KG |
20 |
28 |
40 |
509 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Hyperplasia |
Minimal |
Dead |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Hyperplasia |
Mild |
Moribund |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
C Cell |
12 MG/KG |
50 |
50 |
47 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
Follicular Cel |
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Endocrine System |
Thyroid Gland |
Follicular Cel |
6 MG/KG |
20 |
26 |
29 |
608 |
1 |
Hyperplasia |
Minimal |
Dead |
Endocrine System |
Thyroid Gland |
Follicular Cel |
6 MG/KG |
20 |
21 |
2 |
549 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
Follicular Cel |
6 MG/KG |
20 |
21 |
3 |
555 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
Follicular Cel |
6 MG/KG |
20 |
22 |
8 |
575 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
Follicular Cel |
6 MG/KG |
20 |
23 |
11 |
600 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
Follicular Cel |
6 MG/KG |
20 |
23 |
13 |
515 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
Follicular Cel |
6 MG/KG |
20 |
27 |
33 |
596 |
1 |
Hyperplasia |
Minimal |
Moribund |
Endocrine System |
Thyroid Gland |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Genital System |
Coagulating Gland |
|
Vehicle Control |
36 |
2 |
8 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Coagulating Gland |
|
Vehicle Control |
36 |
4 |
16 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Epididymis |
|
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Angiectasis |
Moderate |
Terminal Sacrifice |
Genital System |
Epididymis |
|
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Genital System |
Epididymis |
|
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Pigmentation |
Mild, Hemosiderin |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
6 |
26 |
731 |
1 |
Hyperplasia |
Marked |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Hyperplasia |
Moderate |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
2 |
6 |
637 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
3 |
11 |
589 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
3 |
14 |
624 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
4 |
19 |
593 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
6 |
27 |
422 |
1 |
Inflammation |
Minimal, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
7 |
34 |
554 |
1 |
Inflammation |
Minimal, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
8 |
40 |
531 |
1 |
Inflammation |
Minimal, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
10 |
47 |
688 |
1 |
Inflammation |
Marked, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
10 |
49 |
627 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
3 |
12 |
690 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
3 |
15 |
515 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
4 |
20 |
410 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
5 |
21 |
695 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
5 |
22 |
674 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
6 |
29 |
711 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
8 |
36 |
719 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
8 |
38 |
719 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
9 |
44 |
725 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
9 |
45 |
676 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
1 |
2 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
1 |
5 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
10 |
46 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
10 |
48 |
733 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
10 |
50 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
2 |
10 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
2 |
7 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
2 |
8 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
3 |
13 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
4 |
16 |
731 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
5 |
23 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
5 |
24 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
5 |
25 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
6 |
26 |
731 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
6 |
28 |
733 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
6 |
30 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
7 |
31 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
7 |
33 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
8 |
37 |
731 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
8 |
39 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
9 |
41 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
9 |
42 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
Vehicle Control |
49 |
9 |
43 |
731 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
22 |
6 |
561 |
1 |
Inflammation |
Minimal, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
25 |
21 |
408 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
26 |
29 |
608 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
27 |
32 |
600 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
29 |
44 |
596 |
1 |
Inflammation |
Minimal, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
21 |
2 |
549 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
21 |
3 |
555 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
22 |
7 |
421 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
22 |
8 |
575 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
23 |
11 |
600 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
23 |
13 |
515 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
23 |
15 |
515 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
27 |
33 |
596 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
27 |
34 |
379 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
28 |
36 |
726 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
6 MG/KG |
17 |
28 |
40 |
509 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
44 |
17 |
367 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Inflammation |
Minimal, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
46 |
27 |
604 |
1 |
Inflammation |
Minimal, Chronic Active |
Dead |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
43 |
13 |
695 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
43 |
14 |
726 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
45 |
22 |
425 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
45 |
23 |
655 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
48 |
39 |
487 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
50 |
49 |
695 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
42 |
9 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
45 |
21 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
47 |
35 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
48 |
40 |
733 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
49 |
42 |
733 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
12 MG/KG |
50 |
50 |
47 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Abscess |
Marked |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Prostate |
|
Vehicle Control |
50 |
3 |
11 |
589 |
1 |
Inflammation |
Marked, Chronic Active |
Dead |
Genital System |
Prostate |
|
Vehicle Control |
50 |
4 |
19 |
593 |
1 |
Inflammation |
Moderate, Chronic Active |
Dead |
Genital System |
Prostate |
|
Vehicle Control |
50 |
6 |
27 |
422 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Prostate |
|
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Prostate |
|
Vehicle Control |
50 |
1 |
4 |
708 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
3 |
15 |
515 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
4 |
18 |
655 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
4 |
20 |
410 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
5 |
21 |
695 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
9 |
45 |
676 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
1 |
2 |
733 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
1 |
5 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
10 |
50 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
2 |
10 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
2 |
8 |
733 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
8 |
37 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
Vehicle Control |
50 |
9 |
43 |
731 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
6 MG/KG |
19 |
22 |
6 |
561 |
1 |
Inflammation |
Moderate, Chronic Active |
Dead |
Genital System |
Prostate |
|
6 MG/KG |
19 |
25 |
21 |
408 |
1 |
Inflammation |
Marked, Chronic Active |
Dead |
Genital System |
Prostate |
|
6 MG/KG |
19 |
26 |
29 |
608 |
1 |
Inflammation |
Moderate, Chronic Active |
Dead |
Genital System |
Prostate |
|
6 MG/KG |
19 |
29 |
44 |
596 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Genital System |
Prostate |
|
6 MG/KG |
19 |
21 |
2 |
549 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Genital System |
Prostate |
|
6 MG/KG |
19 |
22 |
7 |
421 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
6 MG/KG |
19 |
22 |
8 |
575 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
6 MG/KG |
19 |
23 |
12 |
722 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Genital System |
Prostate |
|
6 MG/KG |
19 |
23 |
13 |
515 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
6 MG/KG |
19 |
23 |
15 |
515 |
1 |
Inflammation |
Marked, Chronic Active |
Moribund |
Genital System |
Prostate |
|
6 MG/KG |
19 |
26 |
30 |
708 |
1 |
Inflammation |
Marked, Chronic Active |
Moribund |
Genital System |
Prostate |
|
6 MG/KG |
19 |
27 |
33 |
596 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
6 MG/KG |
19 |
28 |
40 |
509 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
6 MG/KG |
19 |
28 |
38 |
732 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Inflammation |
Minimal, Chronic Active |
Dead |
Genital System |
Prostate |
|
12 MG/KG |
50 |
44 |
17 |
367 |
1 |
Inflammation |
Minimal, Chronic Active |
Dead |
Genital System |
Prostate |
|
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
43 |
13 |
695 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
43 |
14 |
726 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
45 |
22 |
425 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Inflammation |
Marked, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Inflammation |
Marked, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
48 |
37 |
708 |
1 |
Inflammation |
Minimal, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
48 |
39 |
487 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Genital System |
Prostate |
|
12 MG/KG |
50 |
41 |
3 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
48 |
38 |
732 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Genital System |
Prostate |
|
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Genital System |
Seminal Vesicle |
|
6 MG/KG |
16 |
23 |
15 |
515 |
1 |
Inflammation |
Marked, Chronic Active |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Hyperplasia |
Minimal |
Dead |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
4 |
19 |
593 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
6 |
27 |
422 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Hyperplasia |
Minimal |
Dead |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
8 |
40 |
531 |
1 |
Hyperplasia |
Minimal |
Dead |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
10 |
47 |
688 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
4 |
18 |
655 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
5 |
21 |
695 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
5 |
22 |
674 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
6 |
29 |
711 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
9 |
45 |
676 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
10 |
50 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
2 |
10 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
7 |
33 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
Vehicle Control |
50 |
9 |
43 |
731 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
26 |
29 |
608 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
27 |
32 |
600 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
21 |
2 |
549 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
21 |
3 |
555 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
22 |
8 |
575 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
23 |
11 |
600 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
23 |
12 |
722 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
23 |
13 |
515 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
23 |
14 |
641 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
26 |
30 |
708 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
27 |
31 |
641 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
27 |
33 |
596 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
27 |
34 |
379 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
28 |
39 |
684 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
28 |
40 |
509 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
30 |
48 |
697 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
21 |
1 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
21 |
4 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
21 |
5 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
25 |
24 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
26 |
28 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
28 |
37 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
28 |
38 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
29 |
41 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
29 |
43 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
30 |
46 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
30 |
49 |
731 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
6 MG/KG |
48 |
30 |
50 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Hyperplasia |
Minimal |
Dead |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
44 |
17 |
367 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Hyperplasia |
Mild |
Dead |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
45 |
23 |
655 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
48 |
39 |
487 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
50 |
49 |
695 |
1 |
Hyperplasia |
Minimal |
Moribund |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
45 |
21 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
47 |
35 |
732 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
49 |
42 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Hyperplasia |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Interstit Cell |
12 MG/KG |
50 |
50 |
50 |
731 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
Perivascular |
6 MG/KG |
48 |
26 |
26 |
726 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Rete Testes |
6 MG/KG |
48 |
22 |
9 |
695 |
1 |
Hyperplasia |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Atrophy |
Mild |
Dead |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
3 |
11 |
589 |
1 |
Atrophy |
Moderate |
Dead |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
3 |
14 |
624 |
1 |
Atrophy |
Marked |
Dead |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
1 |
4 |
708 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
10 |
47 |
688 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
4 |
18 |
655 |
1 |
Atrophy |
Moderate |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
5 |
21 |
695 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
5 |
22 |
674 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
6 |
29 |
711 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
9 |
45 |
676 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
1 |
2 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
1 |
3 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
2 |
10 |
731 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
3 |
13 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Atrophy |
Moderate |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
5 |
23 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
5 |
25 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
6 |
26 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
6 |
30 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
7 |
33 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
8 |
37 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
Vehicle Control |
50 |
9 |
43 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
24 |
18 |
690 |
1 |
Atrophy |
Marked |
Dead |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
26 |
29 |
608 |
1 |
Atrophy |
Minimal |
Dead |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
27 |
32 |
600 |
1 |
Atrophy |
Marked |
Dead |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
29 |
44 |
596 |
1 |
Atrophy |
Marked |
Dead |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
29 |
45 |
492 |
1 |
Atrophy |
Marked |
Dead |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
21 |
2 |
549 |
1 |
Atrophy |
Moderate |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
21 |
3 |
555 |
1 |
Atrophy |
Moderate |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
22 |
7 |
421 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
22 |
8 |
575 |
1 |
Atrophy |
Minimal |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
22 |
9 |
695 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
23 |
11 |
600 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
23 |
12 |
722 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
23 |
13 |
515 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
25 |
22 |
731 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
26 |
30 |
708 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
27 |
31 |
641 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
28 |
36 |
726 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
28 |
39 |
684 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
28 |
40 |
509 |
1 |
Atrophy |
Mild |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
30 |
48 |
697 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
21 |
1 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
21 |
4 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
21 |
5 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
22 |
10 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
24 |
16 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
24 |
17 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
24 |
20 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
25 |
23 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
25 |
24 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
26 |
27 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
26 |
28 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
27 |
35 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
28 |
37 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
28 |
38 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
29 |
41 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
29 |
42 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
29 |
43 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
30 |
47 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
30 |
49 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
6 MG/KG |
48 |
30 |
50 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Atrophy |
Marked |
Dead |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Atrophy |
Moderate |
Dead |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
46 |
27 |
604 |
1 |
Atrophy |
Marked |
Dead |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
43 |
13 |
695 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
43 |
14 |
726 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
48 |
37 |
708 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
48 |
39 |
487 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Atrophy |
Marked |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
50 |
49 |
695 |
1 |
Atrophy |
Moderate |
Moribund |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
41 |
3 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
41 |
5 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
42 |
9 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
45 |
21 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
47 |
35 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
48 |
38 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
48 |
40 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
49 |
42 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
50 |
47 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
Seminif Tub |
12 MG/KG |
50 |
50 |
50 |
731 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
24 |
18 |
690 |
1 |
Hyperplasia |
Minimal |
Dead |
Genital System |
Testes |
|
6 MG/KG |
48 |
24 |
17 |
732 |
1 |
Hyperplasia |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Mineralization |
Minimal |
Dead |
Genital System |
Testes |
|
Vehicle Control |
50 |
1 |
4 |
708 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
Vehicle Control |
50 |
4 |
18 |
655 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
Vehicle Control |
50 |
5 |
21 |
695 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
Vehicle Control |
50 |
5 |
22 |
674 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
1 |
2 |
733 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
1 |
3 |
731 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
2 |
8 |
733 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
5 |
25 |
733 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
7 |
33 |
732 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
50 |
9 |
43 |
731 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
27 |
32 |
600 |
1 |
Mineralization |
Minimal |
Dead |
Genital System |
Testes |
|
6 MG/KG |
48 |
29 |
44 |
596 |
1 |
Mineralization |
Minimal |
Dead |
Genital System |
Testes |
|
6 MG/KG |
48 |
23 |
12 |
722 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
6 MG/KG |
48 |
23 |
13 |
515 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
6 MG/KG |
48 |
25 |
22 |
731 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
6 MG/KG |
48 |
26 |
30 |
708 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
6 MG/KG |
48 |
27 |
31 |
641 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
6 MG/KG |
48 |
28 |
39 |
684 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
6 MG/KG |
48 |
30 |
48 |
697 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
6 MG/KG |
48 |
22 |
10 |
732 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
24 |
16 |
732 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
24 |
20 |
731 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
26 |
27 |
731 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
26 |
28 |
733 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
27 |
35 |
733 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
28 |
37 |
731 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
28 |
38 |
732 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
29 |
41 |
732 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
6 MG/KG |
48 |
29 |
42 |
732 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Mineralization |
Minimal |
Dead |
Genital System |
Testes |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Mineralization |
Minimal |
Moribund |
Genital System |
Testes |
|
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
12 MG/KG |
50 |
45 |
21 |
732 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Genital System |
Testes |
|
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Mineralization |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Bone Marrow |
Femoral |
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Hyperplasia |
Moderate |
Dead |
Hematopoietic System |
Bone Marrow |
Femoral |
Vehicle Control |
50 |
2 |
8 |
733 |
1 |
Hyperplasia, Reticulum Cell |
Mild, Reticulum Cell |
Terminal Sacrifice |
Hematopoietic System |
Bone Marrow |
Femoral |
12 MG/KG |
50 |
41 |
3 |
731 |
1 |
Hyperplasia, Reticulum Cell |
Minimal, Reticulum Cell |
Terminal Sacrifice |
Hematopoietic System |
Bone Marrow |
Femoral |
6 MG/KG |
16 |
23 |
11 |
600 |
1 |
Myelofibrosis |
Moderate |
Moribund |
Hematopoietic System |
Bone Marrow |
Femoral |
12 MG/KG |
50 |
49 |
42 |
733 |
1 |
Myelofibrosis |
Marked |
Terminal Sacrifice |
Hematopoietic System |
Bone Marrow |
Vertebral |
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Hyperplasia |
Moderate |
Dead |
Hematopoietic System |
Bone Marrow |
Vertebral |
12 MG/KG |
50 |
41 |
3 |
731 |
1 |
Hyperplasia, Reticulum Cell |
Minimal, Reticulum Cell |
Terminal Sacrifice |
Hematopoietic System |
Bone Marrow |
Vertebral |
12 MG/KG |
50 |
49 |
42 |
733 |
1 |
Myelofibrosis |
Marked |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Bronchial |
Vehicle Control |
50 |
5 |
23 |
733 |
1 |
Pigmentation |
Mild, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Bronchial |
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Bronchial |
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Pigmentation |
Mild, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Bronchial |
12 MG/KG |
50 |
48 |
37 |
708 |
1 |
Pigmentation |
Moderate, Hemosiderin |
Moribund |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Cyst |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
50 |
8 |
37 |
731 |
1 |
Cyst |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Cyst |
|
Moribund |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
50 |
1 |
5 |
731 |
1 |
Hyperplasia |
Moderate, Plasma Cell |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
50 |
2 |
10 |
731 |
1 |
Hyperplasia |
Moderate, Plasma Cell |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
Vehicle Control |
50 |
2 |
8 |
733 |
1 |
Hyperplasia |
Mild, Plasma Cell |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mandibular |
6 MG/KG |
25 |
26 |
26 |
726 |
1 |
Hyperplasia |
Moderate, Plasma Cell |
Moribund |
Hematopoietic System |
Lymph Node |
Mandibular |
12 MG/KG |
50 |
45 |
23 |
655 |
1 |
Hyperplasia |
Mild, Plasma Cell |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Hemorrhage |
Marked |
Dead |
Hematopoietic System |
Lymph Node |
Mediastinal |
6 MG/KG |
25 |
23 |
11 |
600 |
1 |
Hyperplasia |
Mild, Plasma Cell |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Moribund |
Hematopoietic System |
Lymph Node |
Mediastinal |
6 MG/KG |
25 |
25 |
21 |
408 |
1 |
Inflammation |
Marked, Chronic Active |
Dead |
Hematopoietic System |
Lymph Node |
Mediastinal |
Vehicle Control |
50 |
6 |
30 |
732 |
1 |
Pigmentation |
Mild, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Pigmentation |
Mild, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Pigmentation |
Minimal, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
6 MG/KG |
25 |
25 |
23 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Hemorrhage |
Moderate |
Dead |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Hemorrhage |
Mild |
Moribund |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Infiltration Cellular |
Moderate, Histiocyte |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
6 MG/KG |
25 |
23 |
12 |
722 |
1 |
Inflammation |
Marked, Proliferative |
Moribund |
Hematopoietic System |
Lymph Node |
Renal |
Vehicle Control |
50 |
3 |
11 |
589 |
1 |
Hemorrhage |
Moderate |
Dead |
Hematopoietic System |
Lymph Node |
Renal |
12 MG/KG |
50 |
49 |
42 |
733 |
1 |
Pigmentation |
Mild, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
6 |
29 |
711 |
1 |
Fibrosis |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Fibrosis |
Marked |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
10 |
50 |
733 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
6 |
26 |
731 |
1 |
Fibrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
23 |
11 |
600 |
1 |
Fibrosis |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
23 |
14 |
641 |
1 |
Fibrosis |
Minimal |
Moribund |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
26 |
26 |
726 |
1 |
Fibrosis |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
30 |
48 |
697 |
1 |
Fibrosis |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
21 |
4 |
732 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
24 |
16 |
732 |
1 |
Fibrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
26 |
28 |
733 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
29 |
42 |
732 |
1 |
Fibrosis |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
29 |
43 |
733 |
1 |
Fibrosis |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
30 |
46 |
732 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Fibrosis |
Marked |
Dead |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Fibrosis |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Fibrosis |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Fibrosis |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Fibrosis |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Fibrosis |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
48 |
38 |
732 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Hematopoietic Cell Proliferation |
Marked |
Dead |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
1 |
4 |
708 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
3 |
15 |
515 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
1 |
3 |
731 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
3 |
13 |
732 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
5 |
25 |
733 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
7 |
33 |
732 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
8 |
37 |
731 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
29 |
45 |
492 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Dead |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Hematopoietic Cell Proliferation |
Moderate |
Dead |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Moribund |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
48 |
38 |
732 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
50 |
50 |
731 |
1 |
Hematopoietic Cell Proliferation |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
6 MG/KG |
49 |
25 |
23 |
732 |
1 |
Hyperplasia |
Moderate, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
50 |
49 |
695 |
1 |
Infarct |
Moderate |
Moribund |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Infiltration Cellular |
Mild, Lipocyte |
Terminal Sacrifice |
Hematopoietic System |
Spleen |
|
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Necrosis |
Mild, Coagulative |
Moribund |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Pigmentation |
Moderate, Hemosiderin |
Moribund |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
48 |
39 |
487 |
1 |
Pigmentation |
Mild, Hemosiderin |
Moribund |
Hematopoietic System |
Spleen |
|
12 MG/KG |
50 |
49 |
42 |
733 |
1 |
Pigmentation |
Mild, Hemosiderin |
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Cyst |
|
Moribund |
Hematopoietic System |
Thymus |
|
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Cyst |
|
Terminal Sacrifice |
Hematopoietic System |
Thymus |
|
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Cyst |
|
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
3 |
11 |
589 |
1 |
Hyperplasia |
Mild, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
3 |
14 |
624 |
1 |
Hyperplasia |
Mild, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
4 |
19 |
593 |
1 |
Hyperplasia |
Marked, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
6 |
27 |
422 |
1 |
Hyperplasia |
Mild, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
8 |
40 |
531 |
1 |
Hyperplasia |
Minimal, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
10 |
49 |
627 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
2 |
9 |
667 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
3 |
15 |
515 |
1 |
Hyperplasia |
Moderate, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
4 |
18 |
655 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
5 |
21 |
695 |
1 |
Hyperplasia |
Marked, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
5 |
22 |
674 |
1 |
Hyperplasia |
Moderate, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
8 |
36 |
719 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
8 |
38 |
719 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
9 |
44 |
725 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
9 |
45 |
676 |
1 |
Hyperplasia |
Minimal, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
1 |
1 |
733 |
1 |
Hyperplasia |
Marked, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
1 |
2 |
733 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
1 |
3 |
731 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
10 |
48 |
733 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
10 |
50 |
733 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
2 |
10 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
2 |
7 |
732 |
1 |
Hyperplasia |
Moderate, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
2 |
8 |
733 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
3 |
13 |
732 |
1 |
Hyperplasia |
Marked, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
4 |
17 |
731 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
5 |
23 |
733 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
5 |
24 |
732 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
6 |
26 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
6 |
28 |
733 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
6 |
30 |
732 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
7 |
31 |
732 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
7 |
32 |
733 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
7 |
33 |
732 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
8 |
37 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
9 |
41 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
9 |
42 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
Vehicle Control |
49 |
9 |
43 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
22 |
6 |
561 |
1 |
Hyperplasia |
Moderate, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
27 |
32 |
600 |
1 |
Hyperplasia |
Mild, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
29 |
44 |
596 |
1 |
Hyperplasia |
Mild, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
29 |
45 |
492 |
1 |
Hyperplasia |
Minimal, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
21 |
2 |
549 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
21 |
3 |
555 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
22 |
7 |
421 |
1 |
Hyperplasia |
Marked, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
23 |
13 |
515 |
1 |
Hyperplasia |
Minimal, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
27 |
33 |
596 |
1 |
Hyperplasia |
Marked, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
27 |
34 |
379 |
1 |
Hyperplasia |
Minimal, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
28 |
40 |
509 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
6 MG/KG |
18 |
30 |
49 |
731 |
1 |
Hyperplasia |
Marked, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Hyperplasia |
Mild, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
44 |
17 |
367 |
1 |
Hyperplasia |
Mild, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Hyperplasia |
Minimal, Cystic |
Dead |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
43 |
13 |
695 |
1 |
Hyperplasia |
Marked, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
43 |
14 |
726 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Hyperplasia |
Marked, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
45 |
22 |
425 |
1 |
Hyperplasia |
Minimal, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Hyperplasia |
Marked, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Hyperplasia |
Moderate, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Hyperplasia |
Moderate, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
48 |
39 |
487 |
1 |
Hyperplasia |
Minimal, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Hyperplasia |
Mild, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Hyperplasia |
Marked, Cystic |
Moribund |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Hyperplasia |
Moderate, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
41 |
3 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
41 |
5 |
733 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Hyperplasia |
Marked, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
42 |
9 |
733 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
45 |
21 |
732 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Hyperplasia |
Moderate, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
48 |
38 |
732 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
48 |
40 |
733 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
50 |
47 |
732 |
1 |
Hyperplasia |
Minimal, Cystic |
Terminal Sacrifice |
Integumentary System |
Mammary Gland |
|
12 MG/KG |
50 |
50 |
50 |
731 |
1 |
Hyperplasia |
Mild, Cystic |
Terminal Sacrifice |
Integumentary System |
Skin |
|
6 MG/KG |
25 |
26 |
29 |
608 |
1 |
Cyst Epithelial Inclusion |
|
Dead |
Integumentary System |
Skin |
|
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Fibrosis |
Mild |
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
|
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Integumentary System |
Skin |
|
6 MG/KG |
25 |
25 |
21 |
408 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Integumentary System |
Skin |
|
6 MG/KG |
25 |
26 |
29 |
608 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Musculoskeletal System |
Bone |
Cranium |
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Fibrous Osteodystrophy |
|
Moribund |
Musculoskeletal System |
Bone |
Cranium |
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Fibrous Osteodystrophy |
|
Moribund |
Musculoskeletal System |
Bone |
Cranium |
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Fibrous Osteodystrophy |
|
Moribund |
Musculoskeletal System |
Bone |
Femur |
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Fibrous Osteodystrophy |
|
Moribund |
Musculoskeletal System |
Bone |
Femur |
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Fibrous Osteodystrophy |
|
Moribund |
Musculoskeletal System |
Bone |
Femur |
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Fibrous Osteodystrophy |
|
Moribund |
Musculoskeletal System |
Bone |
Vertebra |
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Fibrous Osteodystrophy |
|
Moribund |
Musculoskeletal System |
Bone |
Vertebra |
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Fibrous Osteodystrophy |
|
Moribund |
Musculoskeletal System |
Bone |
Vertebra |
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Fibrous Osteodystrophy |
|
Moribund |
Nervous System |
Brain |
White Matter |
Vehicle Control |
48 |
6 |
29 |
711 |
1 |
Degeneration |
Mild |
Moribund |
Nervous System |
Brain |
|
Vehicle Control |
48 |
3 |
11 |
589 |
1 |
Compression |
|
Dead |
Nervous System |
Brain |
|
Vehicle Control |
48 |
1 |
1 |
733 |
1 |
Compression |
|
Terminal Sacrifice |
Nervous System |
Brain |
|
Vehicle Control |
48 |
10 |
46 |
733 |
1 |
Compression |
|
Terminal Sacrifice |
Nervous System |
Brain |
|
Vehicle Control |
48 |
2 |
8 |
733 |
1 |
Compression |
|
Terminal Sacrifice |
Nervous System |
Brain |
|
6 MG/KG |
16 |
26 |
29 |
608 |
1 |
Compression |
|
Dead |
Nervous System |
Brain |
|
6 MG/KG |
16 |
22 |
7 |
421 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
6 MG/KG |
16 |
23 |
15 |
515 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
6 MG/KG |
16 |
27 |
33 |
596 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
43 |
13 |
695 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
45 |
22 |
425 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
45 |
23 |
655 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Compression |
|
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Compression |
|
Terminal Sacrifice |
Nervous System |
Brain |
|
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Compression |
|
Terminal Sacrifice |
Nervous System |
Brain |
|
Vehicle Control |
48 |
3 |
11 |
589 |
1 |
Hemorrhage |
Mild |
Dead |
Nervous System |
Brain |
|
Vehicle Control |
48 |
5 |
21 |
695 |
1 |
Hemorrhage |
Mild |
Moribund |
Nervous System |
Brain |
|
Vehicle Control |
48 |
5 |
22 |
674 |
1 |
Hemorrhage |
Moderate |
Moribund |
Nervous System |
Brain |
|
6 MG/KG |
16 |
26 |
29 |
608 |
1 |
Hemorrhage |
Moderate |
Dead |
Nervous System |
Brain |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Hemorrhage |
Marked |
Moribund |
Nervous System |
Brain |
|
Vehicle Control |
48 |
3 |
11 |
589 |
1 |
Hydrocephalus |
Marked |
Dead |
Nervous System |
Brain |
|
Vehicle Control |
48 |
4 |
20 |
410 |
1 |
Hydrocephalus |
Moderate |
Moribund |
Nervous System |
Brain |
|
6 MG/KG |
16 |
26 |
29 |
608 |
1 |
Hydrocephalus |
Moderate |
Dead |
Nervous System |
Brain |
|
6 MG/KG |
16 |
22 |
7 |
421 |
1 |
Hydrocephalus |
Mild |
Moribund |
Nervous System |
Brain |
|
6 MG/KG |
16 |
23 |
15 |
515 |
1 |
Hydrocephalus |
Mild |
Moribund |
Nervous System |
Brain |
|
6 MG/KG |
16 |
27 |
33 |
596 |
1 |
Hydrocephalus |
Moderate |
Moribund |
Nervous System |
Brain |
|
6 MG/KG |
16 |
27 |
34 |
379 |
1 |
Hydrocephalus |
Marked |
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Hydrocephalus |
Moderate |
Moribund |
Nervous System |
Brain |
|
12 MG/KG |
50 |
43 |
13 |
695 |
1 |
Hydrocephalus |
Mild |
Moribund |
Nervous System |
Brain |
|
Vehicle Control |
48 |
3 |
11 |
589 |
1 |
Inflammation |
Mild, Chronic |
Dead |
Nervous System |
Brain |
|
Vehicle Control |
48 |
3 |
11 |
589 |
1 |
Pigmentation |
Mild, Hemosiderin |
Dead |
Nervous System |
Brain |
|
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Thrombosis |
|
Dead |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
6 |
29 |
711 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
9 |
45 |
676 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
1 |
5 |
731 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
10 |
50 |
733 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Degeneration |
Mild |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
5 |
23 |
733 |
1 |
Degeneration |
Mild |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Degeneration |
Mild |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
6 |
26 |
731 |
1 |
Degeneration |
Mild |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Degeneration |
Mild |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Degeneration |
Mild |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
43 |
12 |
708 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
43 |
14 |
726 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
48 |
36 |
690 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
49 |
41 |
726 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
49 |
44 |
712 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
50 |
49 |
695 |
1 |
Degeneration |
Minimal |
Moribund |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
42 |
6 |
733 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
42 |
7 |
731 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
42 |
9 |
733 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
44 |
16 |
732 |
1 |
Degeneration |
Mild |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
45 |
21 |
732 |
1 |
Degeneration |
Mild |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
45 |
25 |
731 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
46 |
26 |
731 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
47 |
32 |
733 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
47 |
34 |
731 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
48 |
38 |
732 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
48 |
40 |
733 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
49 |
42 |
733 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
49 |
43 |
731 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
49 |
45 |
733 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
White Matter |
12 MG/KG |
49 |
50 |
46 |
731 |
1 |
Degeneration |
Minimal |
Terminal Sacrifice |
Nervous System |
Spinal Cord |
|
Vehicle Control |
50 |
5 |
22 |
674 |
1 |
Hemorrhage |
Mild, Acute |
Moribund |
Respiratory System |
Lung |
Alveolar Epith |
Vehicle Control |
50 |
5 |
22 |
674 |
1 |
Hyperplasia, Adenomatous |
Moderate, Adenomatous |
Moribund |
Respiratory System |
Lung |
Alveolar Epith |
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Hyperplasia, Adenomatous |
Mild, Adenomatous |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Hyperplasia, Adenomatous |
Mild, Adenomatous |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
6 MG/KG |
17 |
29 |
44 |
596 |
1 |
Hyperplasia, Adenomatous |
Marked, Adenomatous |
Dead |
Respiratory System |
Lung |
Alveolar Epith |
6 MG/KG |
17 |
23 |
11 |
600 |
1 |
Hyperplasia, Adenomatous |
Mild, Adenomatous |
Moribund |
Respiratory System |
Lung |
Alveolar Epith |
12 MG/KG |
49 |
47 |
31 |
708 |
1 |
Hyperplasia, Adenomatous |
Moderate, Adenomatous |
Moribund |
Respiratory System |
Lung |
Alveolar Epith |
12 MG/KG |
49 |
42 |
6 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
12 MG/KG |
49 |
49 |
42 |
733 |
1 |
Hyperplasia, Adenomatous |
Mild, Adenomatous |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolar Epith |
12 MG/KG |
49 |
50 |
47 |
732 |
1 |
Hyperplasia, Adenomatous |
Mild, Adenomatous |
Terminal Sacrifice |
Respiratory System |
Lung |
Artery, Mediastinum |
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Necrosis |
Mild, Fibrinoid |
Terminal Sacrifice |
Respiratory System |
Lung |
Artery, Mediastinum |
12 MG/KG |
49 |
46 |
29 |
732 |
1 |
Necrosis |
Mild, Fibrinoid |
Terminal Sacrifice |
Respiratory System |
Lung |
Interstitium |
12 MG/KG |
49 |
45 |
23 |
655 |
1 |
Inflammation |
Minimal, Chronic |
Moribund |
Respiratory System |
Lung |
Interstitium |
12 MG/KG |
49 |
44 |
16 |
732 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Lung |
Interstitium |
12 MG/KG |
49 |
44 |
18 |
731 |
1 |
Inflammation |
Moderate, Chronic |
Terminal Sacrifice |
Respiratory System |
Lung |
Interstitium |
12 MG/KG |
49 |
46 |
29 |
732 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Respiratory System |
Lung |
Mediastinum |
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Lung |
Mediastinum |
12 MG/KG |
49 |
46 |
29 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Lung |
|
6 MG/KG |
17 |
25 |
21 |
408 |
1 |
Bacterium |
|
Dead |
Respiratory System |
Lung |
|
6 MG/KG |
17 |
22 |
7 |
421 |
1 |
Granuloma |
Mild |
Moribund |
Respiratory System |
Lung |
|
6 MG/KG |
17 |
23 |
15 |
515 |
1 |
Granuloma |
Mild |
Moribund |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
1 |
4 |
708 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Inflammation |
Moderate, Chronic Active |
Moribund |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Inflammation |
Minimal, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Lung |
|
6 MG/KG |
17 |
25 |
21 |
408 |
1 |
Inflammation |
Marked, Chronic Active |
Dead |
Respiratory System |
Lung |
|
6 MG/KG |
17 |
23 |
11 |
600 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Respiratory System |
Lung |
|
12 MG/KG |
49 |
44 |
19 |
548 |
1 |
Inflammation |
Moderate, Chronic Active |
Dead |
Respiratory System |
Lung |
|
6 MG/KG |
17 |
23 |
11 |
600 |
1 |
Metaplasia, Osseous |
Minimal, Osseous |
Moribund |
Respiratory System |
Lung |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Mineralization |
Mild |
Moribund |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
10 |
47 |
688 |
1 |
Inflammation |
Minimal, Chronic |
Moribund |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Inflammation |
Moderate, Suppurative |
Moribund |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
6 |
29 |
711 |
1 |
Inflammation |
Mild, Chronic |
Moribund |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Inflammation |
Minimal, Chronic |
Moribund |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Inflammation |
Moderate, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
10 |
50 |
733 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Inflammation |
Marked, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
5 |
23 |
733 |
1 |
Inflammation |
Minimal, Suppurative |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Inflammation |
Moderate, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
5 |
25 |
733 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
8 |
37 |
731 |
1 |
Inflammation |
Mild, Suppurative |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
Vehicle Control |
50 |
9 |
43 |
731 |
1 |
Inflammation |
Mild, Suppurative |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
45 |
23 |
655 |
1 |
Inflammation |
Minimal, Chronic |
Moribund |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Inflammation |
Minimal, Chronic |
Moribund |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
48 |
39 |
487 |
1 |
Inflammation |
Mild, Suppurative |
Moribund |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Inflammation |
Mild, Chronic |
Moribund |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Inflammation |
Minimal, Suppurative |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
42 |
9 |
733 |
1 |
Inflammation |
Moderate, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
47 |
35 |
732 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
48 |
38 |
732 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Inflammation |
Minimal, Suppurative |
Terminal Sacrifice |
Respiratory System |
Nose |
Nasolacrim Dct |
12 MG/KG |
50 |
50 |
50 |
731 |
1 |
Inflammation |
Mild, Chronic |
Terminal Sacrifice |
Respiratory System |
Nose |
|
Vehicle Control |
50 |
3 |
14 |
624 |
1 |
Inflammation |
Moderate, Chronic Active |
Dead |
Respiratory System |
Nose |
|
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Respiratory System |
Nose |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Respiratory System |
Nose |
|
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Nose |
|
6 MG/KG |
16 |
25 |
21 |
408 |
1 |
Inflammation |
Mild, Suppurative |
Dead |
Respiratory System |
Nose |
|
6 MG/KG |
16 |
29 |
45 |
492 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Respiratory System |
Nose |
|
12 MG/KG |
50 |
43 |
14 |
726 |
1 |
Inflammation |
Mild, Chronic Active |
Moribund |
Respiratory System |
Nose |
|
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Inflammation |
Marked, Chronic Active |
Moribund |
Respiratory System |
Trachea |
|
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Inflammation |
Marked, Chronic Active |
Terminal Sacrifice |
Respiratory System |
Trachea |
|
6 MG/KG |
16 |
25 |
21 |
408 |
1 |
Inflammation |
Marked, Chronic Active |
Dead |
Special Senses System |
Eye |
Lens |
Vehicle Control |
4 |
8 |
36 |
719 |
1 |
Cataract |
Moderate |
Moribund |
Special Senses System |
Eye |
Lens |
6 MG/KG |
6 |
22 |
7 |
421 |
1 |
Cataract |
Mild |
Moribund |
Special Senses System |
Eye |
Lens |
12 MG/KG |
6 |
49 |
44 |
712 |
1 |
Cataract |
Marked |
Moribund |
Special Senses System |
Eye |
Lens |
12 MG/KG |
6 |
45 |
21 |
732 |
1 |
Cataract |
Moderate |
Terminal Sacrifice |
Special Senses System |
Eye |
Retina |
Vehicle Control |
4 |
8 |
36 |
719 |
1 |
Atrophy |
Marked |
Moribund |
Special Senses System |
Eye |
Retina |
6 MG/KG |
6 |
22 |
7 |
421 |
1 |
Atrophy |
Marked |
Moribund |
Special Senses System |
Eye |
Retina |
6 MG/KG |
6 |
21 |
4 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Special Senses System |
Eye |
Retina |
12 MG/KG |
6 |
49 |
44 |
712 |
1 |
Atrophy |
Marked |
Moribund |
Special Senses System |
Eye |
Retina |
12 MG/KG |
6 |
45 |
21 |
732 |
1 |
Atrophy |
Marked |
Terminal Sacrifice |
Special Senses System |
Eye |
|
6 MG/KG |
6 |
30 |
49 |
731 |
1 |
Hemorrhage |
Moderate |
Terminal Sacrifice |
Special Senses System |
Eye |
|
12 MG/KG |
6 |
47 |
34 |
731 |
1 |
Hemorrhage |
Marked |
Terminal Sacrifice |
Special Senses System |
Harderian Gland |
|
12 MG/KG |
8 |
48 |
40 |
733 |
1 |
Hemorrhage |
Moderate |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Cyst |
|
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
10 |
731 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
25 |
733 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
23 |
11 |
600 |
1 |
Cyst |
|
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
21 |
4 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
25 |
23 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
26 |
27 |
731 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
28 |
37 |
731 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
29 |
41 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
29 |
42 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
30 |
46 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Cyst |
|
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Cyst |
|
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
45 |
21 |
732 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Cyst |
|
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
26 |
731 |
1 |
Hydronephrosis |
Marked |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
28 |
36 |
726 |
1 |
Inflammation |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
10 |
731 |
1 |
Mineralization |
Mild |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
6 |
637 |
1 |
Nephropathy |
Marked, Chronic |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
11 |
589 |
1 |
Nephropathy |
Moderate, Chronic |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
14 |
624 |
1 |
Nephropathy |
Moderate, Chronic |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
19 |
593 |
1 |
Nephropathy |
Moderate, Chronic |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
27 |
422 |
1 |
Nephropathy |
Mild, Chronic |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
34 |
554 |
1 |
Nephropathy |
Mild, Chronic |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
40 |
531 |
1 |
Nephropathy |
Mild, Chronic |
Dead |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
1 |
4 |
708 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
47 |
688 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
49 |
627 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
9 |
667 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
12 |
690 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
15 |
515 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
18 |
655 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
20 |
410 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
21 |
695 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
22 |
674 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
29 |
711 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
36 |
719 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
38 |
719 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
44 |
725 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
45 |
676 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
1 |
1 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
1 |
2 |
733 |
1 |
Nephropathy |
Mild, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
1 |
3 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
1 |
5 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
46 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
48 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
10 |
50 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
10 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
7 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
2 |
8 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
3 |
13 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
16 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
4 |
17 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
23 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
24 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
5 |
25 |
733 |
1 |
Nephropathy |
Mild, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
26 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
28 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
6 |
30 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
31 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
32 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
33 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
7 |
35 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
37 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
8 |
39 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
41 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
42 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
50 |
9 |
43 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
24 |
18 |
690 |
1 |
Nephropathy |
Marked, Chronic |
Dead |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
25 |
21 |
408 |
1 |
Nephropathy |
Minimal, Chronic |
Dead |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
26 |
29 |
608 |
1 |
Nephropathy |
Moderate, Chronic |
Dead |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
27 |
32 |
600 |
1 |
Nephropathy |
Moderate, Chronic |
Dead |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
29 |
44 |
596 |
1 |
Nephropathy |
Mild, Chronic |
Dead |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
29 |
45 |
492 |
1 |
Nephropathy |
Mild, Chronic |
Dead |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
21 |
2 |
549 |
1 |
Nephropathy |
Minimal, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
21 |
3 |
555 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
22 |
7 |
421 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
22 |
8 |
575 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
22 |
9 |
695 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
23 |
11 |
600 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
23 |
12 |
722 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
23 |
13 |
515 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
23 |
15 |
515 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
24 |
19 |
676 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
25 |
22 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
26 |
30 |
708 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
27 |
31 |
641 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
27 |
33 |
596 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
27 |
34 |
379 |
1 |
Nephropathy |
Minimal, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
28 |
36 |
726 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
28 |
40 |
509 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
21 |
1 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
21 |
4 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
21 |
5 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
25 |
23 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
25 |
24 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
26 |
27 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
28 |
37 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
28 |
38 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
29 |
41 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
29 |
42 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
29 |
43 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
30 |
46 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
6 MG/KG |
37 |
30 |
49 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
41 |
1 |
573 |
1 |
Nephropathy |
Mild, Chronic |
Dead |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
44 |
17 |
367 |
1 |
Nephropathy |
Minimal, Chronic |
Dead |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
44 |
19 |
548 |
1 |
Nephropathy |
Marked, Chronic |
Dead |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
46 |
27 |
604 |
1 |
Nephropathy |
Mild, Chronic |
Dead |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
42 |
10 |
555 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
43 |
12 |
708 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
43 |
13 |
695 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
43 |
14 |
726 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
45 |
22 |
425 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
45 |
23 |
655 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
45 |
24 |
712 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
46 |
28 |
654 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
46 |
30 |
627 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
47 |
31 |
708 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
47 |
33 |
719 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
48 |
36 |
690 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
48 |
37 |
708 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
48 |
39 |
487 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
49 |
41 |
726 |
1 |
Nephropathy |
Moderate, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
49 |
44 |
712 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
50 |
48 |
654 |
1 |
Nephropathy |
Marked, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
50 |
49 |
695 |
1 |
Nephropathy |
Mild, Chronic |
Moribund |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
41 |
2 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
41 |
3 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
41 |
4 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
41 |
5 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
42 |
6 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
42 |
7 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
42 |
8 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
42 |
9 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
43 |
11 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
43 |
15 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
44 |
16 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
44 |
18 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
45 |
21 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
46 |
26 |
731 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
46 |
29 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
47 |
32 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
47 |
34 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
47 |
35 |
732 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
48 |
38 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
48 |
40 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
49 |
42 |
733 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
49 |
43 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
49 |
45 |
733 |
1 |
Nephropathy |
Marked, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
50 |
46 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
50 |
47 |
732 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Kidney |
|
12 MG/KG |
50 |
50 |
50 |
731 |
1 |
Nephropathy |
Moderate, Chronic |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
Transit Epithe |
Vehicle Control |
50 |
2 |
8 |
733 |
1 |
Hyperplasia |
Mild |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
Transit Epithe |
12 MG/KG |
50 |
44 |
20 |
722 |
1 |
Hyperplasia |
Marked |
Moribund |
Urinary System |
Urinary Bladder |
|
Vehicle Control |
50 |
2 |
8 |
733 |
1 |
Inflammation |
Mild, Chronic Active |
Terminal Sacrifice |
Urinary System |
Urinary Bladder |
|
6 MG/KG |
19 |
24 |
18 |
690 |
1 |
Inflammation |
Mild, Chronic Active |
Dead |
Urinary System |
Urinary Bladder |
|
6 MG/KG |
19 |
23 |
15 |
515 |
1 |
Inflammation |
Marked, Chronic Active |
Moribund |
Urinary System |
Urinary Bladder |
|
12 MG/KG |
50 |
45 |
25 |
731 |
1 |
Inflammation |
Moderate, Chronic Active |
Terminal Sacrifice |