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Current Search Critera
Long-Term Study
Individual Animal Clinical Observations
Study Information:
Chemical Name: | Pentachlorophenol, Dowicide EC-7 |
CASRN: | ="87-86-5" |
Study Number: | C55389 |
Exposure Route: | |
TDMS Number: | 0507401 |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Animal Number |
Dose Group |
Clinical Observation |
Qualifier |
Incident Number |
Observation Date |
First Dose Date |
Days On Study |
Removal Observation |
1 |
Untreated Control |
Tissue Mass |
Body Dorsal, 6-10 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
2 |
Untreated Control |
Skinny |
|
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
2 |
Untreated Control |
Tissue Mass |
Body Dorsal, 16-20 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
2 |
Untreated Control |
Alopecia |
Body Ventral |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
3 |
600 PPM |
Rough Hair |
|
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
3 |
Untreated Control |
Bulging Eye |
Left Eye, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
3 |
Untreated Control |
Discoloration |
Left Eye, White |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
3 |
Untreated Control |
Alopecia |
Body Ventral |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
3 |
Untreated Control |
Lesion |
Face, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
3 |
200 PPM |
Extended Abdomen |
|
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
4 |
600 PPM |
Lesion |
Body Dorsal, 6-10 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
4 |
600 PPM |
Alopecia |
Body Dorsal |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
4 |
Untreated Control |
Extended Abdomen |
|
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
4 |
200 PPM |
Swelling |
Body Ventral, 3- 5 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
5 |
100 PPM |
Tissue Mass |
Body Dorsal, 3- 5 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
5 |
200 PPM |
Skinny |
|
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
5 |
600 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
5 |
600 PPM |
Skinny |
|
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
7 |
600 PPM |
Alopecia |
Body Ventral |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
7 |
100 PPM |
Alopecia |
Body Ventral |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
7 |
200 PPM |
Tissue Mass |
Body Ventral, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
7 |
100 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
8 |
200 PPM |
Alopecia |
Body Ventral |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
8 |
100 PPM |
Tissue Mass |
Body Dorsal, 6-10 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
8 |
100 PPM |
Alopecia |
Body Dorsal |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
8 |
100 PPM |
Lesion |
Body Dorsal, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
8 |
600 PPM |
Tissue Mass |
Body Ventral, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
8 |
600 PPM |
Discoloration |
Right Eye, White |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
8 |
600 PPM |
Swelling |
Right Eye, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
8 |
600 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
9 |
100 PPM |
Swelling |
Penis, 0- 2 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
9 |
Untreated Control |
Alopecia |
Entire Animal |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
9 |
600 PPM |
Alopecia |
Body Ventral |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
10 |
100 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
10 |
100 PPM |
Swelling |
Penis, 0- 2 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
10 |
Untreated Control |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
10 |
Untreated Control |
Alopecia |
Body Ventral |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
10 |
Untreated Control |
Swelling |
Penis, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
11 |
Untreated Control |
Missing Anatomy |
Tail, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
12 |
600 PPM |
Lesion |
Body Dorsal, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
12 |
100 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
12 |
100 PPM |
Alopecia |
Body Ventral |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
13 |
Untreated Control |
Alopecia |
Body Ventral |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
13 |
600 PPM |
Alopecia |
Entire Animal |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
14 |
100 PPM |
Lesion |
Body Dorsal, 21-25 Mm |
|
04/15/1984 |
05/12/82 |
705.00 |
Yes |
14 |
100 PPM |
Hunched |
|
|
04/15/1984 |
05/12/82 |
705.00 |
Yes |
14 |
100 PPM |
Tissue Mass |
Body Dorsal, 26 Or Gr |
|
04/15/1984 |
05/12/82 |
705.00 |
Yes |
15 |
100 PPM |
Alopecia |
Body Ventral |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
15 |
Untreated Control |
Lesion |
Face, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
15 |
600 PPM |
Alopecia |
Body Ventral |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
15 |
600 PPM |
Tissue Mass |
Body Ventral, 3- 5 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
16 |
100 PPM |
Tissue Mass |
Body Dorsal, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
16 |
100 PPM |
Lesion |
Body Dorsal, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
16 |
Untreated Control |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
16 |
Untreated Control |
Lesion |
Left Ear, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
17 |
200 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
17 |
600 PPM |
Tissue Mass |
Body Ventral, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
17 |
100 PPM |
Extended Abdomen |
|
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
18 |
600 PPM |
Skinny |
|
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
18 |
200 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
18 |
200 PPM |
Tissue Mass |
Body Dorsal, 3- 5 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
19 |
Untreated Control |
Tissue Mass |
Body Dorsal, 16-20 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
19 |
100 PPM |
Tissue Mass |
Body Dorsal, 6-10 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
19 |
100 PPM |
Skinny |
|
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
19 |
100 PPM |
Swelling |
Penis, 3- 5 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
19 |
100 PPM |
Tissue Mass |
Body Dorsal, 21-25 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
20 |
200 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
20 |
100 PPM |
Swelling |
Right Eye, 6-10 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
20 |
100 PPM |
Tissue Mass |
Body Dorsal, 6-10 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
20 |
100 PPM |
Alopecia |
Body Ventral |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
21 |
Untreated Control |
Alopecia |
Entire Animal |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
21 |
600 PPM |
Skinny |
|
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
21 |
600 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
22 |
600 PPM |
Extended Abdomen |
|
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
23 |
Untreated Control |
Alopecia |
Body Ventral |
|
04/20/1984 |
05/12/82 |
710.00 |
Yes |
23 |
100 PPM |
Alopecia |
Body Ventral |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
23 |
600 PPM |
Alopecia |
Body Ventral |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
23 |
600 PPM |
Swelling |
Penis, 0- 2 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
23 |
600 PPM |
Lesion |
Body Dorsal, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
25 |
100 PPM |
Lesion |
Body Dorsal, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
25 |
100 PPM |
Swelling |
Penis, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
25 |
100 PPM |
Lesion |
Face, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
26 |
Untreated Control |
Swelling |
Penis, 3- 5 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
27 |
600 PPM |
Rough Hair |
|
|
04/05/1984 |
05/12/82 |
695.00 |
Yes |
27 |
600 PPM |
Skinny |
|
|
04/05/1984 |
05/12/82 |
695.00 |
Yes |
27 |
200 PPM |
Extended Abdomen |
|
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
28 |
600 PPM |
Lesion |
Body Dorsal, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
28 |
600 PPM |
Alopecia |
Body Ventral |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
29 |
600 PPM |
Lesion |
Face, Red |
|
04/21/1984 |
05/12/82 |
711.00 |
Yes |
29 |
600 PPM |
Skinny |
|
|
04/21/1984 |
05/12/82 |
711.00 |
Yes |
29 |
600 PPM |
Lesion |
Face, 3- 5 Mm |
|
04/21/1984 |
05/12/82 |
711.00 |
Yes |
29 |
600 PPM |
Hunched |
|
|
04/21/1984 |
05/12/82 |
711.00 |
Yes |
29 |
600 PPM |
Tissue Mass |
Body Dorsal, 0- 2 Mm |
|
04/21/1984 |
05/12/82 |
711.00 |
Yes |
29 |
600 PPM |
Rough Hair |
|
|
04/21/1984 |
05/12/82 |
711.00 |
Yes |
29 |
Untreated Control |
Alopecia |
Body Ventral |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
29 |
100 PPM |
Swelling |
Penis, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
29 |
Untreated Control |
Lesion |
Body Dorsal, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
31 |
100 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
31 |
100 PPM |
Tissue Mass |
Body Dorsal, 6-10 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
31 |
100 PPM |
Tissue Mass |
Body Dorsal, 26 Or Gr |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
31 |
600 PPM |
Extended Abdomen |
|
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
32 |
600 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
32 |
200 PPM |
Lesion |
Body Dorsal, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
34 |
200 PPM |
Tissue Mass |
Body Ventral, 3- 5 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
34 |
Untreated Control |
Alopecia |
Body Ventral |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
35 |
200 PPM |
Tissue Mass |
Body Dorsal, 21-25 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
35 |
100 PPM |
Alopecia |
Body Dorsal |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
35 |
100 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
35 |
600 PPM |
Swelling |
Right Eye, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
36 |
100 PPM |
Alopecia |
Body Dorsal |
|
05/03/1984 |
05/12/82 |
723.00 |
Yes |
36 |
600 PPM |
Extended Abdomen |
|
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
37 |
200 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
39 |
600 PPM |
Skinny |
|
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
39 |
600 PPM |
Swelling |
Penis, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
39 |
600 PPM |
Lesion |
Face, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
39 |
200 PPM |
Rough Hair |
|
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
40 |
100 PPM |
Swelling |
Body Ventral, 3- 5 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
41 |
200 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
42 |
100 PPM |
Tissue Mass |
Body Dorsal, 0- 2 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
42 |
200 PPM |
Alopecia |
Body Ventral |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
42 |
200 PPM |
Tissue Mass |
Body Dorsal, 26 Or Gr |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
42 |
600 PPM |
Swelling |
Penis, 3- 5 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
43 |
100 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
43 |
100 PPM |
Lesion |
Face, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
43 |
100 PPM |
Skinny |
|
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
43 |
100 PPM |
Tissue Mass |
Body Dorsal, 3- 5 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
44 |
100 PPM |
Alopecia |
Body Ventral |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
44 |
600 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
45 |
100 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
45 |
100 PPM |
Alopecia |
Body Ventral |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
45 |
100 PPM |
Tissue Mass |
Body Dorsal, 6-10 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
45 |
600 PPM |
Swelling |
Anal Area, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
45 |
600 PPM |
Discharge |
Anal Area, Red |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
45 |
600 PPM |
Lesion |
Face, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
45 |
600 PPM |
Swelling |
Penis, 3- 5 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
46 |
200 PPM |
Alopecia |
Body Ventral |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
47 |
600 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
48 |
100 PPM |
Lesion |
Body Dorsal, 0- 2 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
48 |
100 PPM |
Lesion |
Face, 0- 2 Mm |
|
05/08/1984 |
05/12/82 |
728.00 |
Yes |
49 |
100 PPM |
Lesion |
Body Ventral, 0- 2 Mm |
|
05/07/1984 |
05/12/82 |
727.00 |
Yes |
49 |
200 PPM |
Missing Anatomy |
Tail, 6-10 Mm |
|
05/09/1984 |
05/12/82 |
729.00 |
Yes |
50 |
600 PPM |
Tissue Mass |
Body (Trunk), 11-15 Mm |
|
04/27/1984 |
05/12/82 |
717.00 |
Yes |
50 |
200 PPM |
Lesion |
Body Ventral, 11-15 Mm |
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
50 |
200 PPM |
Rough Hair |
|
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |
50 |
200 PPM |
Extended Abdomen |
|
|
05/10/1984 |
05/12/82 |
730.00 |
Yes |