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Current Search Critera

Long-Term Study Individual Animal Clinical Observations

Study Information:

Chemical Name: Pentachlorophenol, Dowicide EC-7
CASRN: ="87-86-5"
Study Number: C55389
Exposure Route:
TDMS Number: 0507401
Sex: Male
Strain and Species: B6C3F1 Mice

Animal Number Dose Group Clinical Observation Qualifier Incident Number Observation Date First Dose Date Days On Study Removal Observation
1 Untreated Control Tissue Mass Body Dorsal, 6-10 Mm 05/08/1984 05/12/82 728.00 Yes
2 Untreated Control Skinny 05/07/1984 05/12/82 727.00 Yes
2 Untreated Control Tissue Mass Body Dorsal, 16-20 Mm 05/07/1984 05/12/82 727.00 Yes
2 Untreated Control Alopecia Body Ventral 05/07/1984 05/12/82 727.00 Yes
3 600 PPM Rough Hair 05/07/1984 05/12/82 727.00 Yes
3 Untreated Control Bulging Eye Left Eye, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
3 Untreated Control Discoloration Left Eye, White 05/09/1984 05/12/82 729.00 Yes
3 Untreated Control Alopecia Body Ventral 05/09/1984 05/12/82 729.00 Yes
3 Untreated Control Lesion Face, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
3 200 PPM Extended Abdomen 05/09/1984 05/12/82 729.00 Yes
4 600 PPM Lesion Body Dorsal, 6-10 Mm 05/10/1984 05/12/82 730.00 Yes
4 600 PPM Alopecia Body Dorsal 05/10/1984 05/12/82 730.00 Yes
4 Untreated Control Extended Abdomen 05/10/1984 05/12/82 730.00 Yes
4 200 PPM Swelling Body Ventral, 3- 5 Mm 05/10/1984 05/12/82 730.00 Yes
5 100 PPM Tissue Mass Body Dorsal, 3- 5 Mm 05/07/1984 05/12/82 727.00 Yes
5 200 PPM Skinny 05/07/1984 05/12/82 727.00 Yes
5 600 PPM Lesion Body Dorsal, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
5 600 PPM Skinny 05/09/1984 05/12/82 729.00 Yes
7 600 PPM Alopecia Body Ventral 05/07/1984 05/12/82 727.00 Yes
7 100 PPM Alopecia Body Ventral 05/09/1984 05/12/82 729.00 Yes
7 200 PPM Tissue Mass Body Ventral, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
7 100 PPM Lesion Body Dorsal, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
8 200 PPM Alopecia Body Ventral 05/08/1984 05/12/82 728.00 Yes
8 100 PPM Tissue Mass Body Dorsal, 6-10 Mm 05/08/1984 05/12/82 728.00 Yes
8 100 PPM Alopecia Body Dorsal 05/08/1984 05/12/82 728.00 Yes
8 100 PPM Lesion Body Dorsal, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
8 600 PPM Tissue Mass Body Ventral, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
8 600 PPM Discoloration Right Eye, White 05/09/1984 05/12/82 729.00 Yes
8 600 PPM Swelling Right Eye, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
8 600 PPM Lesion Body Dorsal, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
9 100 PPM Swelling Penis, 0- 2 Mm 05/08/1984 05/12/82 728.00 Yes
9 Untreated Control Alopecia Entire Animal 05/09/1984 05/12/82 729.00 Yes
9 600 PPM Alopecia Body Ventral 05/10/1984 05/12/82 730.00 Yes
10 100 PPM Lesion Body Dorsal, 0- 2 Mm 05/08/1984 05/12/82 728.00 Yes
10 100 PPM Swelling Penis, 0- 2 Mm 05/08/1984 05/12/82 728.00 Yes
10 Untreated Control Lesion Body Dorsal, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
10 Untreated Control Alopecia Body Ventral 05/09/1984 05/12/82 729.00 Yes
10 Untreated Control Swelling Penis, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
11 Untreated Control Missing Anatomy Tail, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
12 600 PPM Lesion Body Dorsal, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
12 100 PPM Lesion Body Dorsal, 0- 2 Mm 05/10/1984 05/12/82 730.00 Yes
12 100 PPM Alopecia Body Ventral 05/10/1984 05/12/82 730.00 Yes
13 Untreated Control Alopecia Body Ventral 05/07/1984 05/12/82 727.00 Yes
13 600 PPM Alopecia Entire Animal 05/08/1984 05/12/82 728.00 Yes
14 100 PPM Lesion Body Dorsal, 21-25 Mm 04/15/1984 05/12/82 705.00 Yes
14 100 PPM Hunched 04/15/1984 05/12/82 705.00 Yes
14 100 PPM Tissue Mass Body Dorsal, 26 Or Gr 04/15/1984 05/12/82 705.00 Yes
15 100 PPM Alopecia Body Ventral 05/09/1984 05/12/82 729.00 Yes
15 Untreated Control Lesion Face, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
15 600 PPM Alopecia Body Ventral 05/10/1984 05/12/82 730.00 Yes
15 600 PPM Tissue Mass Body Ventral, 3- 5 Mm 05/10/1984 05/12/82 730.00 Yes
16 100 PPM Tissue Mass Body Dorsal, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
16 100 PPM Lesion Body Dorsal, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
16 Untreated Control Lesion Body Dorsal, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
16 Untreated Control Lesion Left Ear, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
17 200 PPM Lesion Body Dorsal, 0- 2 Mm 05/07/1984 05/12/82 727.00 Yes
17 600 PPM Tissue Mass Body Ventral, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
17 100 PPM Extended Abdomen 05/08/1984 05/12/82 728.00 Yes
18 600 PPM Skinny 05/08/1984 05/12/82 728.00 Yes
18 200 PPM Lesion Body Dorsal, 0- 2 Mm 05/10/1984 05/12/82 730.00 Yes
18 200 PPM Tissue Mass Body Dorsal, 3- 5 Mm 05/10/1984 05/12/82 730.00 Yes
19 Untreated Control Tissue Mass Body Dorsal, 16-20 Mm 05/09/1984 05/12/82 729.00 Yes
19 100 PPM Tissue Mass Body Dorsal, 6-10 Mm 05/10/1984 05/12/82 730.00 Yes
19 100 PPM Skinny 05/10/1984 05/12/82 730.00 Yes
19 100 PPM Swelling Penis, 3- 5 Mm 05/10/1984 05/12/82 730.00 Yes
19 100 PPM Tissue Mass Body Dorsal, 21-25 Mm 05/10/1984 05/12/82 730.00 Yes
20 200 PPM Lesion Body Dorsal, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
20 100 PPM Swelling Right Eye, 6-10 Mm 05/09/1984 05/12/82 729.00 Yes
20 100 PPM Tissue Mass Body Dorsal, 6-10 Mm 05/09/1984 05/12/82 729.00 Yes
20 100 PPM Alopecia Body Ventral 05/09/1984 05/12/82 729.00 Yes
21 Untreated Control Alopecia Entire Animal 05/07/1984 05/12/82 727.00 Yes
21 600 PPM Skinny 05/08/1984 05/12/82 728.00 Yes
21 600 PPM Lesion Body Dorsal, 0- 2 Mm 05/08/1984 05/12/82 728.00 Yes
22 600 PPM Extended Abdomen 05/08/1984 05/12/82 728.00 Yes
23 Untreated Control Alopecia Body Ventral 04/20/1984 05/12/82 710.00 Yes
23 100 PPM Alopecia Body Ventral 05/07/1984 05/12/82 727.00 Yes
23 600 PPM Alopecia Body Ventral 05/08/1984 05/12/82 728.00 Yes
23 600 PPM Swelling Penis, 0- 2 Mm 05/08/1984 05/12/82 728.00 Yes
23 600 PPM Lesion Body Dorsal, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
25 100 PPM Lesion Body Dorsal, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
25 100 PPM Swelling Penis, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
25 100 PPM Lesion Face, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
26 Untreated Control Swelling Penis, 3- 5 Mm 05/10/1984 05/12/82 730.00 Yes
27 600 PPM Rough Hair 04/05/1984 05/12/82 695.00 Yes
27 600 PPM Skinny 04/05/1984 05/12/82 695.00 Yes
27 200 PPM Extended Abdomen 05/09/1984 05/12/82 729.00 Yes
28 600 PPM Lesion Body Dorsal, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
28 600 PPM Alopecia Body Ventral 05/09/1984 05/12/82 729.00 Yes
29 600 PPM Lesion Face, Red 04/21/1984 05/12/82 711.00 Yes
29 600 PPM Skinny 04/21/1984 05/12/82 711.00 Yes
29 600 PPM Lesion Face, 3- 5 Mm 04/21/1984 05/12/82 711.00 Yes
29 600 PPM Hunched 04/21/1984 05/12/82 711.00 Yes
29 600 PPM Tissue Mass Body Dorsal, 0- 2 Mm 04/21/1984 05/12/82 711.00 Yes
29 600 PPM Rough Hair 04/21/1984 05/12/82 711.00 Yes
29 Untreated Control Alopecia Body Ventral 05/09/1984 05/12/82 729.00 Yes
29 100 PPM Swelling Penis, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
29 Untreated Control Lesion Body Dorsal, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
31 100 PPM Lesion Body Dorsal, 0- 2 Mm 05/07/1984 05/12/82 727.00 Yes
31 100 PPM Tissue Mass Body Dorsal, 6-10 Mm 05/07/1984 05/12/82 727.00 Yes
31 100 PPM Tissue Mass Body Dorsal, 26 Or Gr 05/07/1984 05/12/82 727.00 Yes
31 600 PPM Extended Abdomen 05/09/1984 05/12/82 729.00 Yes
32 600 PPM Lesion Body Dorsal, 0- 2 Mm 05/08/1984 05/12/82 728.00 Yes
32 200 PPM Lesion Body Dorsal, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
34 200 PPM Tissue Mass Body Ventral, 3- 5 Mm 05/07/1984 05/12/82 727.00 Yes
34 Untreated Control Alopecia Body Ventral 05/09/1984 05/12/82 729.00 Yes
35 200 PPM Tissue Mass Body Dorsal, 21-25 Mm 05/08/1984 05/12/82 728.00 Yes
35 100 PPM Alopecia Body Dorsal 05/08/1984 05/12/82 728.00 Yes
35 100 PPM Lesion Body Dorsal, 0- 2 Mm 05/08/1984 05/12/82 728.00 Yes
35 600 PPM Swelling Right Eye, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
36 100 PPM Alopecia Body Dorsal 05/03/1984 05/12/82 723.00 Yes
36 600 PPM Extended Abdomen 05/07/1984 05/12/82 727.00 Yes
37 200 PPM Lesion Body Dorsal, 0- 2 Mm 05/07/1984 05/12/82 727.00 Yes
39 600 PPM Skinny 05/08/1984 05/12/82 728.00 Yes
39 600 PPM Swelling Penis, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
39 600 PPM Lesion Face, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
39 200 PPM Rough Hair 05/09/1984 05/12/82 729.00 Yes
40 100 PPM Swelling Body Ventral, 3- 5 Mm 05/10/1984 05/12/82 730.00 Yes
41 200 PPM Lesion Body Dorsal, 0- 2 Mm 05/10/1984 05/12/82 730.00 Yes
42 100 PPM Tissue Mass Body Dorsal, 0- 2 Mm 05/07/1984 05/12/82 727.00 Yes
42 200 PPM Alopecia Body Ventral 05/07/1984 05/12/82 727.00 Yes
42 200 PPM Tissue Mass Body Dorsal, 26 Or Gr 05/07/1984 05/12/82 727.00 Yes
42 600 PPM Swelling Penis, 3- 5 Mm 05/10/1984 05/12/82 730.00 Yes
43 100 PPM Lesion Body Dorsal, 0- 2 Mm 05/09/1984 05/12/82 729.00 Yes
43 100 PPM Lesion Face, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
43 100 PPM Skinny 05/09/1984 05/12/82 729.00 Yes
43 100 PPM Tissue Mass Body Dorsal, 3- 5 Mm 05/09/1984 05/12/82 729.00 Yes
44 100 PPM Alopecia Body Ventral 05/07/1984 05/12/82 727.00 Yes
44 600 PPM Lesion Body Dorsal, 0- 2 Mm 05/07/1984 05/12/82 727.00 Yes
45 100 PPM Lesion Body Dorsal, 0- 2 Mm 05/07/1984 05/12/82 727.00 Yes
45 100 PPM Alopecia Body Ventral 05/07/1984 05/12/82 727.00 Yes
45 100 PPM Tissue Mass Body Dorsal, 6-10 Mm 05/07/1984 05/12/82 727.00 Yes
45 600 PPM Swelling Anal Area, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
45 600 PPM Discharge Anal Area, Red 05/08/1984 05/12/82 728.00 Yes
45 600 PPM Lesion Face, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
45 600 PPM Swelling Penis, 3- 5 Mm 05/08/1984 05/12/82 728.00 Yes
46 200 PPM Alopecia Body Ventral 05/10/1984 05/12/82 730.00 Yes
47 600 PPM Lesion Body Dorsal, 0- 2 Mm 05/07/1984 05/12/82 727.00 Yes
48 100 PPM Lesion Body Dorsal, 0- 2 Mm 05/08/1984 05/12/82 728.00 Yes
48 100 PPM Lesion Face, 0- 2 Mm 05/08/1984 05/12/82 728.00 Yes
49 100 PPM Lesion Body Ventral, 0- 2 Mm 05/07/1984 05/12/82 727.00 Yes
49 200 PPM Missing Anatomy Tail, 6-10 Mm 05/09/1984 05/12/82 729.00 Yes
50 600 PPM Tissue Mass Body (Trunk), 11-15 Mm 04/27/1984 05/12/82 717.00 Yes
50 200 PPM Lesion Body Ventral, 11-15 Mm 05/10/1984 05/12/82 730.00 Yes
50 200 PPM Rough Hair 05/10/1984 05/12/82 730.00 Yes
50 200 PPM Extended Abdomen 05/10/1984 05/12/82 730.00 Yes