Alimentary System |
Liver |
|
Vehicle Control |
10 |
1 |
1 |
93 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
1 |
4 |
93 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1000 MG/L |
10 |
12 |
56 |
93 |
1 |
Hematopoietic Cell Proliferation |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
62.5 MG/L |
1 |
3 |
14 |
93 |
1 |
Hepatodiaphragmatic Nodule |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
|
250 MG/L |
1 |
8 |
39 |
93 |
1 |
Hepatodiaphragmatic Nodule |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
|
500 MG/L |
1 |
9 |
41 |
93 |
1 |
Hepatodiaphragmatic Nodule |
Minimal |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1000 MG/L |
10 |
12 |
59 |
93 |
1 |
Hepatodiaphragmatic Nodule |
Mild |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
1 |
5 |
93 |
1 |
Inflammation |
Minimal, Focal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
2 |
10 |
93 |
1 |
Inflammation |
Minimal, Focal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
Vehicle Control |
10 |
2 |
6 |
93 |
1 |
Inflammation |
Minimal, Focal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1000 MG/L |
10 |
11 |
51 |
93 |
1 |
Inflammation |
Minimal, Focal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1000 MG/L |
10 |
11 |
53 |
93 |
1 |
Inflammation |
Minimal, Focal, Chronic |
Terminal Sacrifice |
Alimentary System |
Liver |
|
1000 MG/L |
10 |
12 |
58 |
93 |
1 |
Inflammation |
Minimal, Focal, Chronic |
Terminal Sacrifice |
Alimentary System |
Mesentery |
Fat |
Vehicle Control |
1 |
2 |
6 |
93 |
1 |
Necrosis |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
62.5 MG/L |
1 |
3 |
13 |
93 |
1 |
Atrophy |
Mild, Focal |
Terminal Sacrifice |
Alimentary System |
Pancreas |
Acinus |
1000 MG/L |
10 |
12 |
57 |
93 |
1 |
Atrophy |
Minimal, Focal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
Vehicle Control |
10 |
1 |
3 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
Vehicle Control |
10 |
1 |
4 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
Vehicle Control |
10 |
1 |
5 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
Vehicle Control |
10 |
2 |
10 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
Vehicle Control |
10 |
2 |
6 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
Vehicle Control |
10 |
2 |
7 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
Vehicle Control |
10 |
2 |
8 |
93 |
1 |
Basophilic Focus |
Mild |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
1000 MG/L |
10 |
11 |
51 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
1000 MG/L |
10 |
11 |
52 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
1000 MG/L |
10 |
12 |
58 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Alimentary System |
Salivary Glands |
Parotid Gl |
1000 MG/L |
10 |
12 |
59 |
93 |
1 |
Basophilic Focus |
Minimal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
10 |
1 |
1 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
10 |
1 |
3 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
10 |
1 |
5 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
10 |
2 |
10 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
10 |
2 |
7 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
10 |
2 |
8 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
Vehicle Control |
10 |
2 |
9 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
1000 MG/L |
10 |
11 |
51 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
1000 MG/L |
10 |
11 |
52 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
1000 MG/L |
10 |
11 |
53 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
1000 MG/L |
10 |
11 |
54 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
1000 MG/L |
10 |
11 |
55 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
1000 MG/L |
10 |
12 |
56 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
1000 MG/L |
10 |
12 |
57 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
1000 MG/L |
10 |
12 |
58 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Cardiovascular System |
Heart |
|
1000 MG/L |
10 |
12 |
59 |
93 |
1 |
Cardiomyopathy |
Minimal, Focal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
1000 MG/L |
10 |
12 |
59 |
93 |
1 |
Accessory Adrenal Cortical Nodule |
Minimal |
Terminal Sacrifice |
Endocrine System |
Adrenal Cortex |
|
1000 MG/L |
10 |
11 |
53 |
93 |
1 |
Vacuolization Cytoplasmic |
Minimal, Focal |
Terminal Sacrifice |
Endocrine System |
Adrenal Medulla |
|
Vehicle Control |
10 |
1 |
2 |
93 |
1 |
Hyperplasia |
Mild, Focal |
Terminal Sacrifice |
Endocrine System |
Pituitary Gland |
Pars Distalis |
Vehicle Control |
10 |
2 |
7 |
93 |
1 |
Cyst |
Minimal |
Terminal Sacrifice |
Genital System |
Preputial Gland |
|
1000 MG/L |
10 |
12 |
59 |
93 |
1 |
Inflammation |
Minimal, Chronic |
Terminal Sacrifice |
Genital System |
Testes |
|
Vehicle Control |
10 |
2 |
6 |
93 |
1 |
Atrophy |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
62.5 MG/L |
3 |
4 |
16 |
93 |
1 |
Hemorrhage |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mediastinal |
500 MG/L |
2 |
10 |
48 |
93 |
1 |
Hyperplasia |
Minimal, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
62.5 MG/L |
3 |
4 |
19 |
93 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
125 MG/L |
2 |
6 |
30 |
93 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
1000 MG/L |
10 |
11 |
54 |
93 |
1 |
Hyperplasia |
Mild, Lymphoid |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Mesenteric |
Vehicle Control |
10 |
2 |
6 |
93 |
1 |
Inflammation |
Minimal, Granulomatous, Chronic |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
Vehicle Control |
10 |
1 |
3 |
93 |
1 |
Hemorrhage |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
62.5 MG/L |
3 |
3 |
11 |
93 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
250 MG/L |
1 |
8 |
37 |
93 |
1 |
Hemorrhage |
Mild |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
500 MG/L |
2 |
10 |
47 |
93 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
1000 MG/L |
10 |
11 |
51 |
93 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
1000 MG/L |
10 |
11 |
54 |
93 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
1000 MG/L |
10 |
12 |
59 |
93 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Hematopoietic System |
Lymph Node |
Pancreatic |
1000 MG/L |
10 |
12 |
60 |
93 |
1 |
Hemorrhage |
Minimal |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolus |
Vehicle Control |
10 |
1 |
4 |
93 |
1 |
Infiltration Cellular |
Minimal, Focal, Histiocyte |
Terminal Sacrifice |
Respiratory System |
Lung |
Alveolus |
1000 MG/L |
10 |
12 |
57 |
93 |
1 |
Infiltration Cellular |
Minimal, Focal, Histiocyte |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
10 |
1 |
4 |
93 |
1 |
Inflammation |
Minimal, Focal, Chronic |
Terminal Sacrifice |
Respiratory System |
Lung |
|
Vehicle Control |
10 |
1 |
2 |
93 |
1 |
Metaplasia, Osseous |
Minimal, Osseous |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
10 |
1 |
2 |
93 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
10 |
1 |
4 |
93 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
10 |
2 |
10 |
93 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |
Urinary System |
Kidney |
|
Vehicle Control |
10 |
2 |
8 |
93 |
1 |
Nephropathy |
Minimal |
Terminal Sacrifice |