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Long-Term Study
Body Weights
Study Information:
Chemical Name: | Indole-3-carbinol |
CASRN: | ="700-06-1" |
Study Number: | C20006B |
Exposure Route: | GAVAGE |
TDMS Number: | 2000604 |
Sex: | Male |
Strain and Species: | B6C3F1 Mice |
Animal Number |
Cage Number |
Dose Group |
Days On Study |
Week 1 |
Week 2 |
Week 3 |
Week 4 |
Week 5 |
Week 6 |
Week 7 |
Week 8 |
Week 9 |
Week 10 |
Week 11 |
Week 12 |
Week 16 |
Week 19 |
Week 20 |
Week 24 |
Week 28 |
Week 32 |
Week 36 |
Week 40 |
Week 44 |
Week 48 |
Week 51 |
Week 52 |
Week 55 |
Week 56 |
Week 60 |
Week 63 |
Week 64 |
Week 66 |
Week 67 |
Week 68 |
Week 69 |
Week 71 |
Week 72 |
Week 73 |
Week 74 |
Week 75 |
Week 76 |
Week 78 |
Week 80 |
Week 81 |
Week 82 |
Week 83 |
Week 84 |
Week 85 |
Week 86 |
Week 87 |
Week 88 |
Week 89 |
Week 90 |
Week 91 |
Week 92 |
Week 94 |
Week 95 |
Week 96 |
Week 97 |
Week 98 |
Week 99 |
Week 100 |
Week 101 |
Week 102 |
Week 103 |
Week 104 |
Week 105 |
Removal Reason |
1 |
1 |
Vehicle Control |
731 |
25.9 |
26.6 |
28.7 |
30.2 |
32.3 |
33.5 |
33.8 |
36.6 |
36.6 |
37.2 |
40.7 |
40.9 |
44.9 |
|
48.4 |
50.1 |
46.6 |
52.3 |
53.4 |
52.8 |
54.5 |
53.8 |
|
55.2 |
|
49.2 |
57.7 |
|
57.4 |
|
|
59.8 |
|
|
59.2 |
|
|
|
59.3 |
|
60.5 |
|
|
|
60.6 |
|
|
|
62.1 |
|
|
|
62.2 |
|
|
64 |
|
|
|
64.9 |
|
|
|
|
65.4 |
Terminal Sacrifice |
2 |
2 |
Vehicle Control |
673 |
24 |
24 |
26.5 |
26.9 |
29.4 |
29.9 |
31.1 |
32.9 |
32.8 |
31.8 |
34.5 |
34.3 |
39 |
|
42.4 |
47.7 |
48.7 |
51 |
51.9 |
51.6 |
53.9 |
53.5 |
|
54.4 |
|
55.1 |
55.3 |
|
56.7 |
|
|
56.7 |
|
|
57.6 |
|
|
|
58.1 |
|
55.7 |
|
|
|
58.5 |
|
|
|
58.1 |
|
|
|
60.3 |
|
|
58.7 |
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
3 |
3 |
Vehicle Control |
732 |
25.1 |
26.2 |
27.7 |
28.6 |
31.1 |
31.7 |
32.8 |
34.3 |
34.5 |
34.1 |
37 |
37.1 |
41.7 |
|
43.4 |
42.7 |
47.1 |
52.9 |
52.7 |
55.1 |
54.6 |
54.9 |
|
58.3 |
|
57.1 |
59.1 |
|
59.6 |
|
|
59.1 |
|
|
60 |
|
|
|
60.3 |
|
60.9 |
|
|
|
62.4 |
|
|
|
63.2 |
|
|
|
63.9 |
|
|
64.6 |
|
|
|
48.5 |
|
|
|
|
59.6 |
Terminal Sacrifice |
4 |
4 |
Vehicle Control |
732 |
24.1 |
25.4 |
28.2 |
28.8 |
31.5 |
33.3 |
35 |
38.7 |
39.5 |
39.7 |
40 |
41.3 |
47.9 |
|
50.5 |
51.4 |
51.2 |
53.5 |
54.2 |
53.8 |
55.8 |
55.9 |
|
55.1 |
|
51.5 |
49 |
|
49.2 |
|
|
48.7 |
|
|
47.9 |
|
|
|
45 |
|
43.1 |
|
|
|
39.6 |
|
|
|
41.4 |
|
|
|
40.1 |
|
|
37.6 |
|
|
|
31.6 |
|
|
|
|
29.8 |
Terminal Sacrifice |
5 |
5 |
Vehicle Control |
463 |
23.2 |
23.6 |
24.7 |
25.8 |
27.3 |
28.8 |
30.8 |
32.6 |
32.4 |
32.9 |
35.1 |
36 |
39.4 |
|
44.3 |
46.9 |
50.2 |
50.1 |
52.5 |
52 |
54.5 |
55.7 |
|
56 |
|
54.6 |
56.4 |
|
55.7 |
56.3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
6 |
6 |
Vehicle Control |
732 |
23 |
23.9 |
25.2 |
25.6 |
27.8 |
29.5 |
29.7 |
31.9 |
32.2 |
33.4 |
35 |
35.1 |
39.2 |
|
41.8 |
42.6 |
44.9 |
47.6 |
44.7 |
47.2 |
50.8 |
49.3 |
|
51.4 |
|
52.3 |
53.7 |
|
54.2 |
|
|
55.1 |
|
|
54.3 |
|
|
|
56.3 |
|
56.8 |
|
|
|
57 |
|
|
|
57.5 |
|
|
|
57.2 |
|
|
57.2 |
|
|
|
58 |
|
|
|
|
55.4 |
Terminal Sacrifice |
7 |
7 |
Vehicle Control |
730 |
22.7 |
23.3 |
24.8 |
25.3 |
26.5 |
27.4 |
29.2 |
31 |
31.8 |
32.4 |
35.1 |
35.3 |
38.2 |
|
41.9 |
45.7 |
46 |
49.3 |
47.2 |
50.3 |
52.5 |
50 |
|
51.9 |
|
51.9 |
54.8 |
|
52.6 |
|
|
57.1 |
|
|
58 |
|
|
|
56.9 |
|
57.2 |
|
|
|
56.8 |
|
|
|
58.2 |
|
|
|
59.2 |
|
|
59.7 |
|
|
|
56.9 |
|
|
|
|
54.2 |
Terminal Sacrifice |
8 |
8 |
Vehicle Control |
546 |
22.8 |
23.1 |
24.5 |
24.9 |
26.6 |
27.4 |
27.8 |
28.4 |
29 |
29.1 |
30.4 |
30.9 |
33.6 |
|
34.6 |
38.2 |
41.3 |
43.7 |
46.1 |
46.6 |
49.3 |
50.4 |
|
50.9 |
|
50.2 |
50.5 |
|
50.4 |
|
|
48.7 |
|
|
47.9 |
|
|
|
48.1 |
48.2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
9 |
9 |
Vehicle Control |
731 |
22.9 |
24.5 |
26.3 |
27.2 |
28.9 |
29.4 |
31.9 |
33.1 |
34 |
34.8 |
36.2 |
35.9 |
40.4 |
|
45.3 |
47.8 |
51.2 |
52.5 |
53 |
52.5 |
54.3 |
54.5 |
|
54.5 |
|
55.7 |
56.3 |
|
56.6 |
|
|
56.6 |
|
|
55.7 |
|
|
|
56.9 |
|
57.9 |
|
|
|
57.8 |
|
|
|
55.5 |
|
|
|
53.5 |
|
|
49.5 |
|
|
|
46.6 |
|
|
|
|
43.8 |
Terminal Sacrifice |
10 |
10 |
Vehicle Control |
730 |
23 |
23.7 |
25 |
25.3 |
26.9 |
27.7 |
28.9 |
30.5 |
30.7 |
30.6 |
32.6 |
32.9 |
36 |
|
37.7 |
41.9 |
43.2 |
45.2 |
46.9 |
48.6 |
49.2 |
50.7 |
|
51.7 |
|
52.3 |
52.2 |
|
53.6 |
|
|
50.7 |
|
|
53.4 |
|
|
|
54.3 |
|
54.3 |
|
|
|
55.4 |
|
|
|
48.8 |
|
|
|
55.1 |
|
|
57.1 |
|
|
|
58.4 |
|
|
|
|
57.3 |
Terminal Sacrifice |
11 |
11 |
Vehicle Control |
711 |
23.9 |
24.6 |
26.1 |
27.6 |
29.4 |
29.5 |
30.5 |
33.8 |
34.4 |
35.7 |
37.8 |
38.3 |
42 |
|
44.8 |
47 |
47.3 |
51.2 |
51 |
51.5 |
52.2 |
52.6 |
|
52.8 |
|
54 |
52.5 |
|
51.3 |
|
|
48.1 |
|
|
48.7 |
|
|
|
47.3 |
|
43.3 |
|
|
|
41.4 |
|
|
|
40.9 |
|
|
|
39.7 |
|
|
37.6 |
|
|
|
35.3 |
|
34.9 |
|
|
|
Moribund Sacrifice |
12 |
12 |
Vehicle Control |
644 |
24.4 |
24.4 |
25.4 |
26.5 |
28.4 |
29.4 |
31.8 |
33.8 |
33.9 |
34.4 |
36.5 |
37.1 |
41.5 |
|
46.9 |
50.3 |
50.9 |
53.6 |
51.2 |
52.2 |
55.3 |
55.6 |
|
53.5 |
|
56.7 |
55.6 |
|
55.8 |
|
|
54.5 |
|
|
52.6 |
|
|
|
48.7 |
|
42.7 |
|
|
|
38 |
|
|
|
33.1 |
|
|
|
27.1 |
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
13 |
13 |
Vehicle Control |
501 |
26.6 |
27.8 |
30.4 |
30.8 |
33 |
34.4 |
36.2 |
39.1 |
39.5 |
42.6 |
42.7 |
43 |
48.7 |
|
52.2 |
52.5 |
51.9 |
57.4 |
58.8 |
56 |
61.2 |
60 |
|
60.9 |
|
60.3 |
63.4 |
|
62.4 |
|
|
64.8 |
|
|
62.7 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
14 |
14 |
Vehicle Control |
532 |
24.7 |
26.3 |
28.1 |
28.4 |
30.1 |
30.8 |
33 |
36 |
33.9 |
36.3 |
38 |
38.2 |
41.4 |
|
47.4 |
52.6 |
53.2 |
55.8 |
55.5 |
57 |
59.8 |
60.7 |
|
60.3 |
|
60.9 |
61.9 |
|
62.7 |
|
|
64 |
|
|
63.9 |
|
|
|
58.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
15 |
15 |
Vehicle Control |
732 |
24.7 |
25.6 |
26.7 |
27.6 |
29.6 |
30.8 |
33.9 |
35.3 |
36.2 |
37.4 |
40.6 |
39.9 |
44.9 |
|
49.3 |
52.3 |
52.1 |
53.5 |
54.4 |
54.7 |
55.6 |
55.4 |
|
58.3 |
|
57.4 |
59.2 |
|
59.6 |
|
|
60.8 |
|
|
61 |
|
|
|
61.9 |
|
60.9 |
|
|
|
61.7 |
|
|
|
60.9 |
|
|
|
60.4 |
|
|
59.4 |
|
|
|
57.8 |
|
|
|
|
55.1 |
Terminal Sacrifice |
16 |
16 |
Vehicle Control |
732 |
22.2 |
23 |
24.1 |
24.5 |
26.2 |
26.9 |
28.1 |
29.9 |
30.3 |
29.7 |
32.3 |
32.6 |
34.6 |
|
39.2 |
42.4 |
45.9 |
49.7 |
51.1 |
50.2 |
52 |
51.4 |
|
52.4 |
|
53.4 |
52.6 |
|
54.8 |
|
|
53.6 |
|
|
54.4 |
|
|
|
54.2 |
|
54 |
|
|
|
53.6 |
|
|
|
53.8 |
|
|
|
54.1 |
|
|
53.5 |
|
|
|
52.9 |
|
|
|
|
52.8 |
Terminal Sacrifice |
17 |
17 |
Vehicle Control |
731 |
24.4 |
25.1 |
27.2 |
28.2 |
30.5 |
31.6 |
33.8 |
35 |
34.5 |
36 |
38.8 |
37.8 |
39.4 |
|
43.5 |
46.2 |
49.4 |
52 |
52.1 |
52.8 |
54.6 |
56.4 |
|
56.9 |
|
57.5 |
58.7 |
|
60.1 |
|
|
59.8 |
|
|
61.5 |
|
|
|
62.9 |
|
63.8 |
|
|
|
64.2 |
|
|
|
63.9 |
|
|
|
65.4 |
|
|
64.9 |
|
|
|
64.8 |
|
|
|
|
63.6 |
Terminal Sacrifice |
18 |
18 |
Vehicle Control |
732 |
26.2 |
26.5 |
27.7 |
28.2 |
28.2 |
30.5 |
32.8 |
33.6 |
30.9 |
33 |
34.3 |
34.4 |
34.7 |
|
38.6 |
42.2 |
42 |
47.7 |
49.9 |
52.9 |
54.8 |
55 |
|
54.5 |
|
55.1 |
53.4 |
|
47 |
|
|
42.8 |
|
|
45.7 |
|
|
|
45.1 |
|
40.1 |
|
|
|
37 |
|
|
|
34.4 |
|
|
|
31.9 |
|
|
30 |
|
|
|
26.9 |
|
|
|
|
23 |
Terminal Sacrifice |
19 |
19 |
Vehicle Control |
717 |
22.6 |
24.5 |
26.8 |
27.6 |
28.8 |
30 |
33.2 |
34.4 |
36.6 |
36.9 |
38.8 |
38.5 |
41.7 |
|
45.2 |
48.2 |
51.3 |
54.3 |
55.2 |
54.3 |
55.1 |
56.1 |
|
56.8 |
|
57.5 |
56.6 |
|
55.6 |
|
|
52.3 |
|
|
47.7 |
|
|
|
43.1 |
|
40.5 |
|
|
|
38.1 |
|
|
|
35.8 |
|
|
|
34.5 |
|
|
34 |
|
|
|
31.3 |
|
|
25.4 |
|
|
Moribund Sacrifice |
20 |
20 |
Vehicle Control |
731 |
24 |
25.5 |
26.8 |
27.9 |
29.9 |
31.2 |
33.8 |
35.6 |
37.3 |
37 |
38.6 |
38.9 |
30.6 |
|
44.4 |
45.9 |
48.9 |
47.8 |
54.8 |
54 |
56.1 |
56.3 |
|
56.4 |
|
56.8 |
56.8 |
|
58.3 |
|
|
57.5 |
|
|
59.1 |
|
|
|
59.5 |
|
59.1 |
|
|
|
60 |
|
|
|
60.4 |
|
|
|
60.4 |
|
|
61.3 |
|
|
|
62.4 |
|
|
|
|
58.2 |
Terminal Sacrifice |
21 |
21 |
Vehicle Control |
731 |
22.6 |
23.3 |
25 |
25.3 |
27.2 |
27.8 |
29.4 |
30.6 |
30.4 |
30.9 |
32.6 |
33 |
35.5 |
|
38.7 |
41.3 |
42.2 |
45.5 |
48.2 |
49 |
50.4 |
52.3 |
|
52.1 |
|
52.1 |
52.7 |
|
53.4 |
|
|
53 |
|
|
53.8 |
|
|
|
54.2 |
|
53.6 |
|
|
|
54.4 |
|
|
|
54.9 |
|
|
|
52.7 |
|
|
55.2 |
|
|
|
55.8 |
|
|
|
|
55.5 |
Terminal Sacrifice |
22 |
22 |
Vehicle Control |
731 |
23.3 |
24 |
25.7 |
26.9 |
27.9 |
29.9 |
30.8 |
31.8 |
31.8 |
32.5 |
33.3 |
34.8 |
38.7 |
|
40.8 |
42.2 |
44.6 |
48.3 |
49.3 |
51.5 |
52 |
51.8 |
|
52.7 |
|
52.9 |
53.3 |
|
54.5 |
|
|
55.5 |
|
|
55.2 |
|
|
|
55.1 |
|
56.4 |
|
|
|
57.2 |
|
|
|
58.1 |
|
|
|
57 |
|
|
58.1 |
|
|
|
58.5 |
|
|
|
|
56.5 |
Terminal Sacrifice |
23 |
23 |
Vehicle Control |
626 |
24.4 |
25.1 |
26.7 |
27.2 |
29.1 |
30.5 |
32.5 |
33 |
33.4 |
33.5 |
36.2 |
36.1 |
40.1 |
|
43.9 |
45.2 |
50.3 |
52.3 |
53.5 |
51.7 |
53.5 |
54 |
|
55.2 |
|
55.4 |
56 |
|
56.4 |
|
|
57.7 |
|
|
57.2 |
|
|
|
57.6 |
|
53.3 |
|
|
|
47.9 |
|
|
|
44.9 |
|
43.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
24 |
24 |
Vehicle Control |
469 |
24 |
24 |
26 |
26.2 |
28 |
28.2 |
28.1 |
29.1 |
28.7 |
28.6 |
30.7 |
29.1 |
32.7 |
|
34.6 |
33.7 |
34.5 |
37.2 |
36.8 |
41.9 |
43.5 |
46.1 |
|
41.8 |
|
47 |
52.3 |
|
53.4 |
|
54 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
25 |
25 |
Vehicle Control |
680 |
25.2 |
26 |
27.5 |
28.3 |
30.4 |
30.9 |
32.3 |
34 |
35.3 |
34.8 |
37.3 |
36.3 |
41.6 |
|
46.1 |
45.6 |
49.3 |
51.8 |
52 |
51.1 |
52.9 |
54.8 |
|
53.6 |
|
55.7 |
55.6 |
|
53.4 |
|
|
57.3 |
|
|
58.4 |
|
|
|
58.1 |
|
58.5 |
|
|
|
55.9 |
|
|
|
57.5 |
|
|
|
52.1 |
|
|
39.5 |
33.7 |
|
|
|
|
|
|
|
|
Moribund Sacrifice |
26 |
26 |
Vehicle Control |
732 |
22 |
22.3 |
23.8 |
24.9 |
25.9 |
27.7 |
29.1 |
31.3 |
31.9 |
31.5 |
32.9 |
33 |
37.9 |
|
40.6 |
38.6 |
41 |
45.1 |
48.5 |
50.2 |
52 |
49.8 |
|
51.8 |
|
54 |
52.2 |
|
54.5 |
|
|
55.5 |
|
|
56.4 |
|
|
|
56.8 |
|
52.6 |
|
|
|
57.4 |
|
|
|
58.2 |
|
|
|
60 |
|
|
61 |
|
|
|
62.6 |
|
|
|
|
52.7 |
Terminal Sacrifice |
27 |
27 |
Vehicle Control |
732 |
24.6 |
24.5 |
25.8 |
26.3 |
28 |
28.7 |
30.6 |
32.4 |
32.8 |
34 |
35.6 |
34.7 |
40.2 |
|
43.4 |
46.7 |
50.3 |
54 |
54.8 |
54.8 |
55.3 |
55.3 |
|
55.8 |
|
56.1 |
57.7 |
|
57.8 |
|
|
59.7 |
|
|
59.1 |
|
|
|
60.2 |
|
61 |
|
|
|
60.9 |
|
|
|
62 |
|
|
|
62.2 |
|
|
62.6 |
|
|
|
64 |
|
|
|
|
62.3 |
Terminal Sacrifice |
28 |
28 |
Vehicle Control |
525 |
23.2 |
23.8 |
26 |
25.4 |
26.8 |
28.2 |
29.5 |
27.4 |
31.6 |
32.4 |
34.5 |
34.5 |
39.1 |
|
40.5 |
45.1 |
47.4 |
51.1 |
50.8 |
51.6 |
52.5 |
53 |
|
52.7 |
|
53.8 |
55.2 |
|
53.5 |
|
|
57.2 |
|
|
56.5 |
|
|
44.3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
29 |
29 |
Vehicle Control |
728 |
24.8 |
25.4 |
27.3 |
28.1 |
31 |
32.2 |
34.7 |
35.8 |
35.9 |
37.1 |
39.1 |
38.3 |
42.5 |
|
46.6 |
46.3 |
50.7 |
51.9 |
51.4 |
52.6 |
53.9 |
54.8 |
|
54.3 |
|
54.6 |
54.9 |
|
56.2 |
|
|
55.8 |
|
|
56.4 |
|
|
|
57.3 |
|
56.5 |
|
|
|
59 |
|
|
|
59.3 |
|
|
|
57.9 |
|
|
56.1 |
|
|
|
48 |
|
|
|
42 |
|
Natural Death |
30 |
30 |
Vehicle Control |
619 |
23.2 |
25.1 |
26.7 |
27.2 |
29.2 |
29.8 |
31.1 |
32.4 |
31.9 |
33.5 |
35.5 |
34.5 |
30.8 |
|
39 |
41.5 |
42.9 |
46.1 |
47.9 |
51.1 |
53.5 |
53.5 |
|
55.3 |
|
55.3 |
54.5 |
|
53.4 |
|
|
53.9 |
|
|
52.6 |
|
|
|
53.2 |
|
49.9 |
|
|
|
48.7 |
|
|
|
40.2 |
37.4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
31 |
31 |
Vehicle Control |
629 |
24.8 |
25.4 |
28.1 |
28.2 |
29.7 |
31.2 |
33.1 |
29.5 |
32.7 |
34.2 |
37.2 |
36.4 |
41.9 |
|
45.3 |
47.8 |
50.1 |
52.7 |
54.5 |
53.4 |
55 |
54.9 |
|
56 |
|
56.3 |
53.9 |
|
58 |
|
|
57.8 |
|
|
53.1 |
|
|
|
55.7 |
|
59 |
|
|
|
58.7 |
|
|
|
57.8 |
|
48.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
32 |
32 |
Vehicle Control |
730 |
24.5 |
25.3 |
26.7 |
27.8 |
28.7 |
29.9 |
31.5 |
32.2 |
33.6 |
34.6 |
35.7 |
35.7 |
39.1 |
|
42.6 |
45.6 |
48.1 |
52.8 |
51.9 |
53.6 |
56.7 |
56.4 |
|
56.6 |
|
56.2 |
57.9 |
|
58 |
|
|
58.9 |
|
|
58.9 |
|
|
|
59 |
|
59.4 |
|
|
|
59.8 |
|
|
|
58.9 |
|
|
|
57.5 |
|
|
52.6 |
|
|
|
45.8 |
|
|
|
|
41.3 |
Terminal Sacrifice |
33 |
33 |
Vehicle Control |
589 |
24.1 |
24.6 |
26.7 |
27.5 |
29.4 |
30.4 |
32.7 |
35 |
36.2 |
36.3 |
38.7 |
38.3 |
41.2 |
|
47.3 |
49.8 |
51 |
52.2 |
52.7 |
52.8 |
54.2 |
54.6 |
|
55.2 |
|
56.5 |
56.5 |
|
58.1 |
|
|
58.2 |
|
|
58.8 |
|
|
|
59.3 |
|
57.2 |
|
|
|
36.9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
34 |
34 |
Vehicle Control |
732 |
25.2 |
25.8 |
27.4 |
28.5 |
30.7 |
31.8 |
33.8 |
34.8 |
33.5 |
35.2 |
37.7 |
36.8 |
34.4 |
|
39.2 |
42.7 |
46 |
51 |
52.3 |
52.3 |
54.4 |
55.2 |
|
55.9 |
|
55.9 |
55.9 |
|
56.5 |
|
|
57.6 |
|
|
56.8 |
|
|
|
58.6 |
|
59.1 |
|
|
|
58.7 |
|
|
|
60.8 |
|
|
|
60.3 |
|
|
54.3 |
|
|
|
61.8 |
|
|
|
|
63.2 |
Terminal Sacrifice |
35 |
35 |
Vehicle Control |
731 |
22.2 |
22.7 |
24.4 |
24.9 |
26.8 |
27.7 |
29.7 |
27.4 |
30.7 |
31.6 |
33.7 |
33.3 |
36.7 |
|
39.5 |
44.7 |
46.2 |
50 |
49.6 |
51.1 |
52.9 |
53.1 |
|
54.1 |
|
53.3 |
55.1 |
|
56.4 |
|
|
55.2 |
|
|
55 |
|
|
|
56.3 |
|
56.1 |
|
|
|
56.4 |
|
|
|
57.4 |
|
|
|
57.1 |
|
|
57.4 |
|
|
|
59.1 |
|
|
|
|
54.8 |
Terminal Sacrifice |
36 |
36 |
Vehicle Control |
610 |
25.7 |
26.8 |
28.4 |
29.5 |
31.2 |
33.5 |
36 |
37.7 |
37.7 |
39.9 |
41.4 |
41.1 |
44.1 |
|
48.2 |
50.4 |
49.6 |
52.1 |
52 |
51.8 |
53.7 |
50.9 |
|
51.6 |
|
51 |
50.2 |
|
46.2 |
|
|
43.1 |
|
|
40.5 |
|
|
|
36 |
|
31 |
|
|
|
27.8 |
|
|
25.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
37 |
37 |
Vehicle Control |
354 |
21.8 |
22.4 |
23.8 |
24.5 |
26.6 |
27.4 |
29.5 |
30.6 |
31.7 |
32.8 |
34.3 |
34.7 |
39.4 |
|
43.8 |
47.3 |
46.9 |
49.5 |
48 |
49.3 |
51.6 |
50.7 |
48.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
38 |
38 |
Vehicle Control |
730 |
23.2 |
23.7 |
25.5 |
25.6 |
27.1 |
27.9 |
30.1 |
32.7 |
33 |
34.8 |
37.1 |
38.2 |
41.9 |
|
46.7 |
49.1 |
49.7 |
52.1 |
51.7 |
51.2 |
51.5 |
51.5 |
|
53.3 |
|
53.2 |
54.2 |
|
53.8 |
|
|
53.8 |
|
|
54.4 |
|
|
|
54.6 |
|
53.8 |
|
|
|
54.5 |
|
|
|
52.6 |
|
|
|
48.4 |
|
|
44.7 |
|
|
|
41.7 |
|
|
|
|
39.5 |
Terminal Sacrifice |
39 |
39 |
Vehicle Control |
483 |
22.3 |
23.3 |
24.9 |
25 |
26.7 |
27.9 |
29.3 |
29.6 |
31.9 |
33.4 |
34.8 |
34.7 |
39.1 |
|
40.3 |
45.3 |
47.3 |
49.9 |
50.3 |
49.5 |
49.8 |
48.8 |
|
49 |
|
47.5 |
45.7 |
|
47.8 |
|
|
43.5 |
42.6 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
40 |
40 |
Vehicle Control |
732 |
23.7 |
24.5 |
26.1 |
26.3 |
28 |
29.3 |
31.2 |
27.6 |
31.7 |
32.3 |
33.3 |
33 |
37.4 |
|
39.4 |
42.4 |
44.4 |
48.1 |
49.1 |
50.5 |
52.1 |
52.3 |
|
53.6 |
|
55.3 |
55.1 |
|
56 |
|
|
56 |
|
|
56.3 |
|
|
|
55.6 |
|
56.2 |
|
|
|
57.8 |
|
|
|
59 |
|
|
|
58.9 |
|
|
59.1 |
|
|
|
59 |
|
|
|
|
59.4 |
Terminal Sacrifice |
41 |
41 |
Vehicle Control |
519 |
23.5 |
23.8 |
24.3 |
25.5 |
27.8 |
28 |
30.3 |
30.9 |
31.9 |
33.2 |
34.3 |
35.1 |
39.6 |
|
44.3 |
47.8 |
51.9 |
52.5 |
51.6 |
52.7 |
53.7 |
53.2 |
|
53.6 |
|
54.9 |
55.2 |
|
56.3 |
|
|
58.5 |
|
|
55 |
|
48.9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
42 |
42 |
Vehicle Control |
465 |
23.1 |
23.6 |
24.7 |
24.7 |
26.5 |
26.9 |
28.5 |
31.5 |
32.2 |
33.7 |
34.8 |
35.6 |
38.5 |
|
43.8 |
47.6 |
48 |
50.4 |
49.7 |
49.9 |
52.4 |
53.5 |
|
52.8 |
|
51.6 |
52.9 |
|
54.4 |
|
52.6 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
43 |
43 |
Vehicle Control |
731 |
22.6 |
23.3 |
24.7 |
25.9 |
26.6 |
27.8 |
29.4 |
31.1 |
31 |
32.2 |
33.2 |
34.3 |
30 |
|
36.3 |
41.7 |
45.6 |
49.6 |
50.4 |
48.4 |
52.7 |
54 |
|
54.6 |
|
54.4 |
55.5 |
|
56 |
|
|
57.4 |
|
|
56.8 |
|
|
|
57.4 |
|
57.6 |
|
|
|
58.5 |
|
|
|
58.5 |
|
|
|
57.9 |
|
|
57.6 |
|
|
|
59.5 |
|
|
|
|
59 |
Terminal Sacrifice |
44 |
44 |
Vehicle Control |
731 |
23.6 |
24.7 |
26.6 |
26.8 |
28.5 |
31 |
31.6 |
33.7 |
35.1 |
36.3 |
38.2 |
38.2 |
41.8 |
|
45.5 |
48.9 |
51.7 |
53.3 |
54 |
51.5 |
55.4 |
55.8 |
|
56.3 |
|
45 |
55.6 |
|
60.2 |
|
|
52.3 |
|
|
60.1 |
|
|
|
61.8 |
|
62.2 |
|
|
|
63.5 |
|
|
|
63.9 |
|
|
|
62.6 |
|
|
61.8 |
|
|
|
56.6 |
|
|
|
|
40.9 |
Terminal Sacrifice |
45 |
45 |
Vehicle Control |
731 |
25.6 |
26.7 |
29.4 |
29.8 |
31.6 |
34.5 |
37.1 |
33 |
38.3 |
39.3 |
41.2 |
41.9 |
46.9 |
|
49.3 |
53.4 |
52.5 |
55.4 |
54.8 |
55.4 |
58.1 |
58.1 |
|
58.2 |
|
58.3 |
53.5 |
|
60.7 |
|
|
60.5 |
|
|
60.1 |
|
|
|
61.7 |
|
62.1 |
|
|
|
63.1 |
|
|
|
61.9 |
|
|
|
52.4 |
|
|
58.9 |
|
|
|
57.8 |
|
|
|
|
40.8 |
Terminal Sacrifice |
46 |
46 |
Vehicle Control |
730 |
24.4 |
25 |
26.7 |
27.3 |
29.4 |
31.6 |
33.8 |
35.9 |
37.6 |
38 |
38.9 |
39.2 |
45.2 |
|
48.5 |
50.6 |
51 |
53.2 |
54 |
55.2 |
56.9 |
57.5 |
|
57.5 |
|
58 |
59.3 |
|
58.3 |
|
|
57.3 |
|
|
59 |
|
|
|
58.7 |
|
60.2 |
|
|
|
61.4 |
|
|
|
63.4 |
|
|
|
62.8 |
|
|
63.5 |
|
|
|
60.4 |
|
|
|
|
56.7 |
Terminal Sacrifice |
47 |
47 |
Vehicle Control |
732 |
23.5 |
24.7 |
26.5 |
27.6 |
28.9 |
30.4 |
31.9 |
32.4 |
32.4 |
32.9 |
35.5 |
35.1 |
37.4 |
|
41.3 |
41.1 |
42.3 |
46.4 |
49.5 |
52.2 |
53.5 |
53.5 |
|
55.6 |
|
55.3 |
54 |
|
54.2 |
|
|
55.8 |
|
|
56.4 |
|
|
|
56.6 |
|
57.1 |
|
|
|
57.7 |
|
|
|
58.7 |
|
|
|
58.6 |
|
|
59.5 |
|
|
|
59.5 |
|
|
|
|
60.1 |
Terminal Sacrifice |
48 |
48 |
Vehicle Control |
723 |
23.4 |
24.3 |
25.5 |
26 |
26.9 |
27.5 |
29.4 |
30.3 |
31.9 |
33 |
34.8 |
34.3 |
39.5 |
|
42.4 |
45.2 |
48.6 |
51.5 |
50.8 |
51.8 |
53.9 |
53.4 |
|
54.5 |
|
54.1 |
53.9 |
|
55.5 |
|
|
55.6 |
|
|
56.5 |
|
|
|
57.4 |
|
57 |
|
|
|
57 |
|
|
|
58 |
|
|
|
59.2 |
|
|
59.7 |
|
|
|
52.6 |
|
|
|
48.4 |
|
Moribund Sacrifice |
49 |
49 |
Vehicle Control |
662 |
24.2 |
25.1 |
27.2 |
28.8 |
30.1 |
32.5 |
35.6 |
37.1 |
37.1 |
38.2 |
41.1 |
41.2 |
49.3 |
|
51.1 |
51.6 |
52.1 |
54.8 |
55.5 |
56.1 |
57.9 |
59.7 |
|
58.2 |
|
59 |
59.5 |
|
59.4 |
|
|
57.1 |
|
|
55 |
|
|
|
52.1 |
|
48.9 |
|
|
|
45.3 |
|
|
|
44 |
|
|
|
40.7 |
|
38.3 |
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
50 |
50 |
Vehicle Control |
697 |
26.3 |
28 |
29.7 |
30.2 |
31.9 |
32.8 |
35.6 |
37.7 |
38.3 |
39.1 |
40.8 |
41.2 |
45.9 |
|
48.8 |
52.3 |
52.7 |
55.7 |
55.9 |
55.7 |
57.3 |
57.5 |
|
57.3 |
|
57.2 |
58.4 |
|
59.2 |
|
|
58.4 |
|
|
60.1 |
|
|
|
60.7 |
|
60.1 |
|
|
|
61.2 |
|
|
|
57.8 |
|
|
|
53.1 |
|
|
49 |
|
|
|
40.2 |
|
|
|
|
|
Moribund Sacrifice |
51 |
51 |
62.5mg/kg |
732 |
24.3 |
25.3 |
27.3 |
28.8 |
30 |
31.2 |
33.4 |
35 |
37.2 |
38.3 |
40 |
40.8 |
44.4 |
|
48.1 |
49.9 |
50.3 |
52 |
52.5 |
51.5 |
54.3 |
54.4 |
|
54.5 |
|
55.3 |
55.6 |
|
56.7 |
|
|
57.2 |
|
|
54.2 |
|
|
|
57.6 |
|
58.4 |
|
|
|
58.9 |
|
|
|
57.8 |
|
|
|
54.2 |
|
|
48.7 |
|
|
|
44.1 |
|
|
|
|
36.8 |
Terminal Sacrifice |
52 |
52 |
62.5mg/kg |
582 |
24.5 |
25.6 |
27.7 |
29.3 |
30.4 |
32.5 |
34.2 |
36 |
35.5 |
36 |
39.2 |
38.3 |
43.9 |
|
48.9 |
49.7 |
49 |
51.3 |
51.8 |
53 |
53.8 |
54.8 |
|
56.4 |
|
57.4 |
58.6 |
|
58.3 |
|
|
59.1 |
|
|
58.1 |
|
|
|
58.8 |
|
58.4 |
|
|
55.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
53 |
53 |
62.5mg/kg |
673 |
22.7 |
23.9 |
25 |
25.4 |
27.5 |
28 |
28.8 |
30.8 |
31.6 |
32.7 |
34.3 |
34.4 |
38.4 |
|
40.4 |
43 |
44.2 |
47.2 |
49.6 |
49.5 |
51.1 |
52.3 |
|
51.9 |
|
52 |
52.3 |
|
53.3 |
|
|
52.3 |
|
|
53.2 |
|
|
|
52.4 |
|
52.9 |
|
|
|
53.1 |
|
|
|
52.9 |
|
|
|
52.8 |
|
|
49.6 |
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
54 |
54 |
62.5mg/kg |
731 |
24 |
24.3 |
25.4 |
26.7 |
28 |
29.1 |
30.8 |
31.1 |
32.7 |
33.9 |
35 |
35.6 |
38.8 |
|
41.7 |
45.8 |
45.1 |
52.2 |
53.3 |
52.7 |
53.2 |
54.6 |
|
54.5 |
|
55.3 |
55.7 |
|
56.3 |
|
|
57.3 |
|
|
56.1 |
|
|
|
56 |
|
55 |
|
|
|
55.1 |
|
|
|
54.3 |
|
|
|
50.1 |
|
|
46.7 |
|
|
|
43.8 |
|
|
|
|
41.3 |
Terminal Sacrifice |
55 |
55 |
62.5mg/kg |
682 |
24.5 |
26.2 |
28.3 |
29.4 |
31.8 |
32.7 |
34.1 |
34.9 |
35.1 |
37.5 |
39 |
39.4 |
43.2 |
|
48.8 |
50.3 |
51 |
56 |
54.9 |
55.5 |
56.3 |
55 |
|
51.9 |
|
56.4 |
57.2 |
|
56.8 |
|
|
56.9 |
|
|
53.5 |
|
|
|
54.1 |
|
54.1 |
|
|
|
47.7 |
|
|
|
40.5 |
|
|
|
37.6 |
|
|
37.2 |
|
29.3 |
|
|
|
|
|
|
|
Moribund Sacrifice |
56 |
56 |
62.5mg/kg |
731 |
22.9 |
23.5 |
24.8 |
25.2 |
26.3 |
27.7 |
30 |
31.6 |
32.1 |
33.6 |
34.7 |
34.8 |
39.3 |
|
43.7 |
47.4 |
50.6 |
52.7 |
51.2 |
50.9 |
53.4 |
53.6 |
|
52.9 |
|
54.3 |
54.8 |
|
54.4 |
|
|
56.1 |
|
|
57.1 |
|
|
|
56.9 |
|
55.6 |
|
|
|
55.8 |
|
|
|
56.6 |
|
|
|
56.3 |
|
|
56.6 |
|
|
|
57.3 |
|
|
|
|
53.4 |
Terminal Sacrifice |
57 |
57 |
62.5mg/kg |
730 |
24.5 |
25.7 |
27.4 |
28.5 |
29.5 |
31.6 |
32.1 |
32.9 |
34.6 |
35.1 |
37.4 |
37.8 |
39.5 |
|
44.1 |
46.9 |
49.1 |
53.6 |
52.5 |
51.1 |
52.7 |
53.2 |
|
55.2 |
|
54.1 |
54.7 |
|
56.6 |
|
|
57.1 |
|
|
57 |
|
|
|
56.5 |
|
57.8 |
|
|
|
58.1 |
|
|
|
58.6 |
|
|
|
59.2 |
|
|
60.3 |
|
|
|
59.8 |
|
|
|
|
61.3 |
Terminal Sacrifice |
58 |
58 |
62.5mg/kg |
694 |
24.3 |
24.7 |
25.9 |
27.2 |
29 |
29 |
31.4 |
33.3 |
32.8 |
33.4 |
35.9 |
36.1 |
38.2 |
|
42.3 |
44.8 |
47.5 |
51.3 |
52.7 |
52.1 |
53.5 |
53.4 |
|
54.7 |
|
54.5 |
55.8 |
|
55.5 |
|
|
55.8 |
|
|
56 |
|
|
|
56.8 |
|
56.7 |
|
|
|
57.3 |
|
|
|
55.3 |
|
|
|
45.4 |
|
|
37.3 |
|
|
32.8 |
|
|
|
|
|
|
Moribund Sacrifice |
59 |
59 |
62.5mg/kg |
573 |
26.2 |
27.2 |
29.7 |
30.9 |
33 |
33.9 |
36.3 |
38.8 |
38.4 |
41.5 |
43.3 |
42.8 |
50 |
|
52.7 |
53.3 |
52.6 |
55.4 |
57.3 |
57.6 |
57.4 |
58.1 |
|
59.6 |
|
60.8 |
62.1 |
|
63.2 |
|
|
64.5 |
|
|
65.3 |
|
|
|
65.7 |
|
67.5 |
|
68.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
60 |
60 |
62.5mg/kg |
732 |
24.2 |
24.3 |
26.2 |
27.5 |
29.9 |
30.5 |
33.1 |
34.3 |
35.4 |
37 |
39.1 |
38.9 |
44.9 |
|
48.6 |
50.6 |
50 |
51.7 |
51.9 |
52.4 |
55.7 |
54.9 |
|
55.3 |
|
56.1 |
56.7 |
|
56.6 |
|
|
57.1 |
|
|
57.7 |
|
|
|
58.9 |
|
59.2 |
|
|
|
59.8 |
|
|
|
61.2 |
|
|
|
61.2 |
|
|
59.5 |
|
|
|
57 |
|
|
|
|
55.8 |
Terminal Sacrifice |
61 |
61 |
62.5mg/kg |
631 |
25.4 |
26.7 |
28.7 |
30.4 |
32.3 |
33.9 |
35.9 |
38.4 |
39.7 |
41.9 |
44 |
43.5 |
49.4 |
|
52.5 |
51.4 |
53.5 |
54.2 |
55.2 |
56.4 |
59.6 |
58.4 |
|
59.9 |
|
60.8 |
61.8 |
|
62.1 |
|
|
62.8 |
|
|
64.2 |
|
|
|
63.3 |
|
63.9 |
|
|
|
62.2 |
|
|
|
50.9 |
|
39.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
62 |
62 |
62.5mg/kg |
732 |
25.7 |
27.7 |
31.1 |
32.2 |
34.8 |
37.2 |
39.5 |
41.7 |
43.2 |
44.6 |
45.6 |
46.7 |
49.3 |
|
52.7 |
53.7 |
53.7 |
56.5 |
56.3 |
56.4 |
61.1 |
60.9 |
|
60.1 |
|
61.8 |
61.8 |
|
60.1 |
|
|
61 |
|
|
63 |
|
|
|
62.4 |
|
64.5 |
|
|
|
61.9 |
|
|
|
63.4 |
|
|
|
59.2 |
|
|
53.3 |
|
|
|
47.7 |
|
|
|
|
37.9 |
Terminal Sacrifice |
63 |
63 |
62.5mg/kg |
701 |
22.5 |
23.1 |
24.9 |
25.7 |
26.9 |
28.8 |
31 |
32.4 |
32.4 |
33.7 |
34.8 |
34.8 |
39.7 |
|
44.3 |
48.4 |
47.5 |
51 |
52.4 |
52.5 |
54.1 |
55.8 |
|
55.9 |
|
56.5 |
56.7 |
|
56.3 |
|
|
57.8 |
|
|
57.9 |
|
|
|
59.5 |
|
50.9 |
|
|
|
60.8 |
|
|
|
61.3 |
|
|
|
60.5 |
|
|
62.1 |
|
|
|
58.9 |
|
|
|
|
|
Moribund Sacrifice |
64 |
64 |
62.5mg/kg |
730 |
23.4 |
23.8 |
25.3 |
25.6 |
27.2 |
28.4 |
28.9 |
29.6 |
29.5 |
29.8 |
31.3 |
30.3 |
32.7 |
|
35.8 |
38.3 |
38.6 |
41.2 |
43.5 |
44.5 |
47.6 |
49.1 |
|
51.1 |
|
52.4 |
52.4 |
|
52.5 |
|
|
52.9 |
|
|
52.7 |
|
|
|
54.2 |
|
51.8 |
|
|
|
54.3 |
|
|
|
54.6 |
|
|
|
55.2 |
|
|
54.9 |
|
|
|
55.5 |
|
|
|
|
55.5 |
Terminal Sacrifice |
65 |
65 |
62.5mg/kg |
716 |
22.8 |
24 |
26 |
27.7 |
29.8 |
31.4 |
33.1 |
34.4 |
35.9 |
36.6 |
39.7 |
39.3 |
42.9 |
|
48 |
50.4 |
50.3 |
52.7 |
51.8 |
52.5 |
53.5 |
55.3 |
|
55.1 |
|
55.6 |
56.7 |
|
55.9 |
|
|
57.7 |
|
|
57.7 |
|
|
|
58.4 |
|
58.6 |
|
|
|
58.9 |
|
|
|
58.8 |
|
|
|
58.7 |
|
|
58.1 |
|
|
|
54.4 |
|
|
36.2 |
|
|
Moribund Sacrifice |
66 |
66 |
62.5mg/kg |
630 |
25.1 |
26.6 |
29.2 |
30.3 |
33.2 |
35.1 |
37.7 |
39.5 |
41 |
42.3 |
45.6 |
45.9 |
50.1 |
|
52.6 |
52.4 |
53 |
54 |
54.6 |
56.4 |
58.8 |
58.7 |
|
58.8 |
|
56 |
59.2 |
|
59.5 |
|
|
59 |
|
|
58.1 |
|
|
|
57.5 |
|
53.8 |
|
|
|
51 |
|
|
|
44 |
|
44.4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
67 |
67 |
62.5mg/kg |
692 |
25.2 |
27.2 |
29.1 |
28.9 |
31.4 |
33.1 |
33.4 |
35.3 |
36.6 |
36.5 |
39.4 |
37.9 |
42 |
|
44.5 |
46.8 |
51.1 |
55.7 |
54.8 |
56.2 |
57.7 |
58 |
|
52.9 |
|
59.9 |
60.6 |
|
60.6 |
|
|
62 |
|
|
56.8 |
|
|
|
62.5 |
|
55.6 |
|
|
|
64.5 |
|
|
|
62.1 |
|
|
|
58.7 |
|
|
58.1 |
|
|
54.2 |
|
|
|
|
|
|
Natural Death |
68 |
68 |
62.5mg/kg |
658 |
23.7 |
24.7 |
26.5 |
27.9 |
30.4 |
31.9 |
33.2 |
34.7 |
35.3 |
35.6 |
38 |
37.7 |
42.7 |
|
47.4 |
49.4 |
51 |
53.5 |
52.1 |
52.3 |
53.4 |
52.6 |
|
52.8 |
|
53.5 |
54 |
|
52.8 |
|
|
52.1 |
|
|
51.2 |
|
|
|
47 |
|
40.4 |
|
|
|
40.1 |
|
|
|
36.8 |
|
|
|
33 |
29.4 |
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
69 |
69 |
62.5mg/kg |
730 |
22.8 |
23.9 |
25.8 |
26 |
27.6 |
29.4 |
30.1 |
31 |
31.9 |
33.1 |
35.2 |
34.3 |
38.8 |
|
42.1 |
43.9 |
46.9 |
51.1 |
51.7 |
52.5 |
53.6 |
53.8 |
|
54.6 |
|
57 |
56.5 |
|
56.8 |
|
|
57.8 |
|
|
57.9 |
|
|
|
58.5 |
|
58.9 |
|
|
|
60.2 |
|
|
|
61.5 |
|
|
|
61.2 |
|
|
60.5 |
|
|
|
63.6 |
|
|
|
|
51.4 |
Terminal Sacrifice |
70 |
70 |
62.5mg/kg |
682 |
24.9 |
24.8 |
26.7 |
27.6 |
29.2 |
30.2 |
32.7 |
34.1 |
36 |
37.2 |
38.8 |
39.1 |
45.1 |
|
48.7 |
50.1 |
50.6 |
52.7 |
53.4 |
53.2 |
55.3 |
56.4 |
|
56.7 |
|
56.5 |
56.7 |
|
56.7 |
|
|
58.9 |
|
|
58.6 |
|
|
|
61.7 |
|
59.6 |
|
|
|
59.8 |
|
|
|
60.4 |
|
|
|
53.7 |
|
|
42 |
|
33.1 |
|
|
|
|
|
|
|
Moribund Sacrifice |
71 |
71 |
62.5mg/kg |
714 |
23.5 |
24.1 |
25.5 |
26.4 |
27.9 |
28.5 |
30.7 |
31.9 |
33.9 |
33.3 |
35.7 |
35.5 |
38.8 |
|
39.6 |
41.8 |
44.3 |
48.7 |
49.9 |
49.2 |
50.3 |
51.1 |
|
51.8 |
|
53.2 |
53.8 |
|
54.2 |
|
|
54.6 |
|
|
54.4 |
|
|
|
55.2 |
|
52.6 |
|
|
|
54.4 |
|
|
|
56.3 |
|
|
|
56.3 |
|
|
57.2 |
|
|
|
57 |
|
49.8 |
|
|
|
Natural Death |
72 |
72 |
62.5mg/kg |
731 |
24.1 |
24.4 |
25.8 |
26.4 |
28 |
29.4 |
31.1 |
32.8 |
34.8 |
34.6 |
37.5 |
37.1 |
42.4 |
|
48.3 |
52.2 |
53.8 |
54.5 |
53.2 |
54.9 |
55.2 |
55.4 |
|
57.8 |
|
58.3 |
59.7 |
|
59.9 |
|
|
60.1 |
|
|
59.9 |
|
|
|
60.6 |
|
61.1 |
|
|
|
62 |
|
|
|
63 |
|
|
|
62.6 |
|
|
61.5 |
|
|
|
62.8 |
|
|
|
|
61.5 |
Terminal Sacrifice |
73 |
73 |
62.5mg/kg |
731 |
21.9 |
22.4 |
23.6 |
24.2 |
25.8 |
26.9 |
27.3 |
30 |
30.6 |
31 |
33.2 |
33.5 |
37.4 |
|
39.2 |
43.3 |
45 |
48.2 |
49.8 |
50.4 |
51.2 |
51 |
|
52.9 |
|
53.1 |
54.1 |
|
53.7 |
|
|
54.3 |
|
|
54.2 |
|
|
|
54.8 |
|
55.1 |
|
|
|
56.4 |
|
|
|
56.3 |
|
|
|
56.8 |
|
|
57.5 |
|
|
|
57.8 |
|
|
|
|
59.7 |
Terminal Sacrifice |
74 |
74 |
62.5mg/kg |
732 |
24.9 |
25.5 |
27 |
27.8 |
29 |
29 |
31 |
32.6 |
33.8 |
34.3 |
37.4 |
37.2 |
43.8 |
|
47.5 |
51.3 |
49.6 |
52.7 |
52.3 |
52.5 |
54.1 |
53.7 |
|
55.5 |
|
56.6 |
57.2 |
|
58.4 |
|
|
59.1 |
|
|
59.2 |
|
|
|
59.2 |
|
49.5 |
|
|
|
56 |
|
|
|
60.1 |
|
|
|
60.6 |
|
|
61.3 |
|
|
|
62.5 |
|
|
|
|
59.3 |
Terminal Sacrifice |
75 |
75 |
62.5mg/kg |
732 |
24.9 |
26 |
26.8 |
28.3 |
29.2 |
30.1 |
32 |
33.8 |
35.1 |
35.5 |
37.7 |
37.7 |
41.9 |
|
44.8 |
48.3 |
49.6 |
51.8 |
51.2 |
51.5 |
52.2 |
51.9 |
|
52.2 |
|
52.8 |
52.4 |
|
51.8 |
|
|
52.2 |
|
|
52 |
|
|
|
51.3 |
|
50.1 |
|
|
|
49.2 |
|
|
|
45.2 |
|
|
|
40.8 |
|
|
38.3 |
|
|
|
37 |
|
|
|
|
34.4 |
Terminal Sacrifice |
76 |
76 |
62.5mg/kg |
732 |
23.7 |
24.6 |
26 |
26.7 |
29.1 |
29.8 |
31 |
31.1 |
32.1 |
33.2 |
36 |
36.2 |
41.3 |
|
45.2 |
47.7 |
46.9 |
50.2 |
48.9 |
49.6 |
51.5 |
51.9 |
|
52 |
|
54 |
56.1 |
|
55 |
|
|
56.6 |
|
|
56.9 |
|
|
|
57.1 |
|
58.3 |
|
|
|
58.9 |
|
|
|
59.3 |
|
|
|
60 |
|
|
61.2 |
|
|
|
61.5 |
|
|
|
|
60.4 |
Terminal Sacrifice |
77 |
77 |
62.5mg/kg |
731 |
24.4 |
25.4 |
27.7 |
28.5 |
31 |
31.8 |
33.5 |
36.2 |
37.4 |
38.6 |
40.3 |
40.2 |
45.9 |
|
49.9 |
51.3 |
50.6 |
54 |
53.6 |
54.1 |
57.6 |
56.5 |
|
56.9 |
|
57.5 |
57.9 |
|
58.4 |
|
|
59.3 |
|
|
59.4 |
|
|
|
59.9 |
|
60.5 |
|
|
|
60.7 |
|
|
|
61.4 |
|
|
|
61.5 |
|
|
62.5 |
|
|
|
63.1 |
|
|
|
|
63.6 |
Terminal Sacrifice |
78 |
78 |
62.5mg/kg |
732 |
24.5 |
25.1 |
26.7 |
27.8 |
30.2 |
31.3 |
32.1 |
34.1 |
35.1 |
36.1 |
38.2 |
38.3 |
42.5 |
|
48.4 |
50.6 |
50.8 |
53.2 |
53.1 |
53.2 |
53.9 |
53.2 |
|
53.8 |
|
53.8 |
54 |
|
53.5 |
|
|
52.6 |
|
|
52.1 |
|
|
|
50 |
|
48.7 |
|
|
|
45.7 |
|
|
|
42.6 |
|
|
|
40.4 |
|
|
38.6 |
|
|
|
37 |
|
|
|
|
35.9 |
Terminal Sacrifice |
79 |
79 |
62.5mg/kg |
709 |
24.2 |
24.8 |
26.5 |
27.4 |
28.9 |
30.7 |
31.8 |
32.4 |
33.6 |
34.9 |
36.9 |
37.3 |
40.1 |
|
43 |
47.1 |
46.6 |
52.7 |
52.6 |
51.4 |
51.7 |
51.6 |
|
53.4 |
|
52.8 |
54.2 |
|
54.7 |
|
|
55.4 |
|
|
54.9 |
|
|
|
56.2 |
|
55.7 |
|
|
|
54.4 |
|
|
|
56.6 |
|
|
|
57.4 |
|
|
57.7 |
|
|
|
56.9 |
|
51.5 |
|
|
|
Natural Death |
80 |
80 |
62.5mg/kg |
732 |
24.2 |
25.1 |
26.7 |
27.9 |
29.4 |
30.9 |
32.4 |
34.5 |
34.8 |
35.9 |
38.7 |
39.6 |
44.3 |
|
47.8 |
52.8 |
53.1 |
54.2 |
54.8 |
54.9 |
56.8 |
56.6 |
|
57.4 |
|
58.4 |
58.9 |
|
59.4 |
|
|
60.7 |
|
|
61.8 |
|
|
|
63.3 |
|
64.2 |
|
|
|
62.5 |
|
|
|
60 |
|
|
|
61.3 |
|
|
53.7 |
|
|
|
53.4 |
|
|
|
|
50.3 |
Terminal Sacrifice |
81 |
81 |
62.5mg/kg |
710 |
23.6 |
24.8 |
26 |
27 |
28.3 |
29.3 |
30.8 |
32.3 |
32.3 |
33 |
35.9 |
35.5 |
40.4 |
|
42.1 |
45.7 |
46.2 |
51.7 |
51.5 |
52.1 |
53.2 |
51.8 |
|
55 |
|
54.3 |
55 |
|
55.9 |
|
|
55.5 |
|
|
57.1 |
|
|
|
57.4 |
|
56.2 |
|
|
|
54.9 |
|
|
|
56.3 |
|
|
|
53.6 |
|
|
48.8 |
|
|
|
39.4 |
|
35.4 |
|
|
|
Moribund Sacrifice |
82 |
82 |
62.5mg/kg |
732 |
24.1 |
25.3 |
26.9 |
28.1 |
29.6 |
29.9 |
31.6 |
32.8 |
34.4 |
35 |
36.3 |
35.9 |
38.7 |
|
40.9 |
43.4 |
45.8 |
48.8 |
50.4 |
51.5 |
53.6 |
51.9 |
|
54.8 |
|
55.7 |
55.6 |
|
50.7 |
|
|
56 |
|
|
56.4 |
|
|
|
56.8 |
|
56.2 |
|
|
|
57.5 |
|
|
|
58.9 |
|
|
|
57.9 |
|
|
58.1 |
|
|
|
58.9 |
|
|
|
|
58.9 |
Terminal Sacrifice |
83 |
83 |
62.5mg/kg |
732 |
23.4 |
24.2 |
25.8 |
27.3 |
28.5 |
30.2 |
31.6 |
32.6 |
32.3 |
33.4 |
36.6 |
36.1 |
41 |
|
45 |
47.8 |
50.3 |
51.7 |
50.1 |
51.9 |
53.4 |
53.1 |
|
54.6 |
|
55.8 |
55.6 |
|
56.4 |
|
|
57 |
|
|
58.2 |
|
|
|
59.3 |
|
59.9 |
|
|
|
61 |
|
|
|
61.2 |
|
|
|
61.2 |
|
|
58.9 |
|
|
|
56 |
|
|
|
|
52.4 |
Terminal Sacrifice |
84 |
84 |
62.5mg/kg |
731 |
22.7 |
23.6 |
25.4 |
26.5 |
28.3 |
30.1 |
31 |
32.5 |
32.9 |
34.2 |
35 |
35.7 |
40.2 |
|
43 |
48.2 |
49 |
50.6 |
50.4 |
50.5 |
51.3 |
50.8 |
|
52.5 |
|
53.3 |
53.2 |
|
52.9 |
|
|
53.7 |
|
|
54.1 |
|
|
|
54.4 |
|
53.8 |
|
|
|
55.5 |
|
|
|
55.5 |
|
|
|
55.7 |
|
|
56.7 |
|
|
|
57.8 |
|
|
|
|
58.1 |
Terminal Sacrifice |
85 |
85 |
62.5mg/kg |
732 |
27.4 |
28.2 |
30.7 |
31.2 |
33.6 |
33.8 |
36.1 |
36.7 |
36.5 |
38.3 |
40.3 |
40.7 |
47.4 |
|
49.5 |
53.7 |
47.5 |
55.5 |
53.9 |
55.9 |
57.1 |
58.7 |
|
59.9 |
|
58 |
60 |
|
60.4 |
|
|
61.1 |
|
|
61.4 |
|
|
|
60 |
|
57.9 |
|
|
|
54.7 |
|
|
|
49.1 |
|
|
|
47.2 |
|
|
48.3 |
|
|
|
50.6 |
|
|
|
|
57.1 |
Terminal Sacrifice |
86 |
86 |
62.5mg/kg |
732 |
23.9 |
24.8 |
26.9 |
28.1 |
29.9 |
31.4 |
30 |
32.9 |
33.7 |
33.9 |
37 |
36.2 |
40.9 |
|
44.6 |
45.9 |
48.6 |
50.2 |
49.5 |
52.6 |
55 |
55.3 |
|
56.5 |
|
57.8 |
57.7 |
|
55.1 |
|
|
55.2 |
|
|
56.2 |
|
|
|
55.8 |
|
54.8 |
|
|
|
53.7 |
|
|
|
51.5 |
|
|
|
47 |
|
|
43.8 |
|
|
|
39.4 |
|
|
|
|
40 |
Terminal Sacrifice |
87 |
87 |
62.5mg/kg |
731 |
25.4 |
25.7 |
27.2 |
27.8 |
29.1 |
30.5 |
31.6 |
32.3 |
33.9 |
33.3 |
35.4 |
35.2 |
37.4 |
|
39.2 |
35.4 |
43.2 |
47.2 |
48 |
49.9 |
52.7 |
52.7 |
|
53.3 |
|
54.5 |
54.2 |
|
55.2 |
|
|
56 |
|
|
55.6 |
|
|
|
56 |
|
56.8 |
|
|
|
57 |
|
|
|
58.6 |
|
|
|
57.4 |
|
|
58.6 |
|
|
|
60.5 |
|
|
|
|
61.2 |
Terminal Sacrifice |
88 |
88 |
62.5mg/kg |
731 |
24.5 |
25.1 |
26.1 |
27.5 |
29.4 |
30.8 |
31.2 |
32.7 |
33.2 |
34.1 |
36.9 |
38 |
42.8 |
|
46.7 |
52.6 |
52.4 |
54.4 |
53.7 |
53.7 |
55 |
55.2 |
|
55.8 |
|
57.2 |
59.1 |
|
60.6 |
|
|
60.5 |
|
|
60.5 |
|
|
|
61.3 |
|
61.9 |
|
|
|
59.8 |
|
|
|
54.7 |
|
|
|
49.7 |
|
|
43.4 |
|
|
|
40 |
|
|
|
|
36.4 |
Terminal Sacrifice |
89 |
89 |
62.5mg/kg |
604 |
23.8 |
25 |
27.5 |
29.3 |
32.1 |
33 |
34.9 |
37.2 |
37.5 |
37.7 |
40.9 |
40.5 |
45.5 |
|
49.6 |
51 |
50.6 |
52.9 |
51.8 |
52.8 |
54.3 |
54.5 |
|
56.1 |
|
56.5 |
56.5 |
|
56.2 |
|
|
57.3 |
|
|
58.3 |
|
|
|
59.4 |
|
50.9 |
|
|
|
58.1 |
|
|
57.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
90 |
90 |
62.5mg/kg |
732 |
25.9 |
27.1 |
28.9 |
30.1 |
32.3 |
32.2 |
32.5 |
34.5 |
36.4 |
36.8 |
40.3 |
40 |
44.1 |
|
46.8 |
50.9 |
51.9 |
55.4 |
53.4 |
54.4 |
55 |
55.4 |
|
50.5 |
|
55.6 |
55.4 |
|
57.7 |
|
|
58.2 |
|
|
57.1 |
|
|
|
56.7 |
|
58.4 |
|
|
|
55.6 |
|
|
|
56.5 |
|
|
|
56.7 |
|
|
58.1 |
|
|
|
58.7 |
|
|
|
|
58.1 |
Terminal Sacrifice |
91 |
91 |
62.5mg/kg |
711 |
23.6 |
24.5 |
26.1 |
27.4 |
29.6 |
31.1 |
32.4 |
33.9 |
34.1 |
36.1 |
36.6 |
37.1 |
40.4 |
|
43.6 |
45.2 |
48 |
52.4 |
52.5 |
52.1 |
53.1 |
52 |
|
52.9 |
|
53.3 |
51.8 |
|
51 |
|
|
48.5 |
|
|
43.6 |
|
|
|
39.7 |
|
35.3 |
|
|
|
34.3 |
|
|
|
33.8 |
|
|
|
31.5 |
|
|
30.5 |
|
|
|
29.4 |
|
30 |
|
|
|
Moribund Sacrifice |
92 |
92 |
62.5mg/kg |
381 |
23.2 |
23.9 |
26.4 |
27.1 |
29.6 |
29.8 |
31.2 |
33.2 |
34.4 |
35.7 |
37.1 |
36.2 |
42.8 |
|
46.3 |
49.3 |
49.5 |
52.1 |
52.4 |
53.7 |
54.1 |
55.1 |
|
60 |
62.8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
93 |
93 |
62.5mg/kg |
732 |
25 |
26.1 |
28 |
29.9 |
31 |
32.4 |
33.7 |
35.9 |
37.4 |
38.6 |
40.1 |
41.1 |
46.3 |
|
48.8 |
52.3 |
53.6 |
54.8 |
54.9 |
55.3 |
59.3 |
58.9 |
|
59.8 |
|
60 |
61.5 |
|
60.5 |
|
|
61.2 |
|
|
61.5 |
|
|
|
63.7 |
|
62.4 |
|
|
|
63 |
|
|
|
62.5 |
|
|
|
61.6 |
|
|
59.8 |
|
|
|
61.1 |
|
|
|
|
55.3 |
Terminal Sacrifice |
94 |
94 |
62.5mg/kg |
731 |
24.8 |
25.5 |
27.2 |
28.6 |
31.3 |
33.3 |
34.9 |
37.5 |
38.9 |
39.7 |
41.4 |
41.7 |
46.9 |
|
51 |
52.1 |
51.6 |
53.6 |
54.2 |
55 |
57.8 |
59.4 |
|
59.4 |
|
59.2 |
60.9 |
|
62.4 |
|
|
63.1 |
|
|
63.7 |
|
|
|
64.7 |
|
65.6 |
|
|
|
66.9 |
|
|
|
66.4 |
|
|
|
62 |
|
|
53.9 |
|
|
|
54.8 |
|
|
|
|
46.7 |
Terminal Sacrifice |
95 |
95 |
62.5mg/kg |
731 |
23.5 |
22.8 |
23.8 |
25 |
25.1 |
26.5 |
27.6 |
29.3 |
28.6 |
28.7 |
29.7 |
31.1 |
34.6 |
|
37.2 |
40.2 |
43.6 |
46.1 |
48.7 |
48.9 |
51.7 |
51.9 |
|
52.7 |
|
53.4 |
53.2 |
|
53.1 |
|
|
53.9 |
|
|
53.9 |
|
|
|
55 |
|
54.4 |
|
|
|
55.1 |
|
|
|
56.9 |
|
|
|
56.1 |
|
|
54.4 |
|
|
|
55.7 |
|
|
|
|
57.1 |
Terminal Sacrifice |
96 |
96 |
62.5mg/kg |
732 |
23.4 |
24 |
25.8 |
25.8 |
27.9 |
28.9 |
31.1 |
33.4 |
34.6 |
36.1 |
35.3 |
35.4 |
40.8 |
|
47.2 |
48.2 |
51.3 |
53.2 |
53.2 |
53.7 |
56.6 |
55.5 |
|
56.8 |
|
57 |
57.2 |
|
58.2 |
|
|
58.3 |
|
|
59 |
|
|
|
57.6 |
|
57.1 |
|
|
|
60 |
|
|
|
60 |
|
|
|
60.4 |
|
|
60.6 |
|
|
|
58.3 |
|
|
|
|
59.6 |
Terminal Sacrifice |
97 |
97 |
62.5mg/kg |
732 |
22.6 |
23.6 |
23.8 |
24.6 |
25.9 |
27.4 |
28.1 |
29.2 |
31.1 |
32.4 |
34.3 |
34.8 |
37.5 |
|
41.4 |
44.7 |
46.2 |
50.2 |
52 |
51.6 |
51.5 |
53 |
|
55.2 |
|
54.7 |
53.8 |
|
55.9 |
|
|
59.7 |
|
|
58.5 |
|
|
|
58.9 |
|
59.1 |
|
|
|
60.5 |
|
|
|
60.7 |
|
|
|
62.5 |
|
|
65 |
|
|
|
63.3 |
|
|
|
|
65.2 |
Terminal Sacrifice |
98 |
98 |
62.5mg/kg |
730 |
24.7 |
25.8 |
27.9 |
29 |
30.8 |
31.7 |
34.3 |
36.1 |
37.5 |
38.1 |
40.5 |
40.4 |
46.8 |
|
48.6 |
49.7 |
47.6 |
49.6 |
52.1 |
53.2 |
55.4 |
55.7 |
|
56.4 |
|
58.5 |
57.8 |
|
59.2 |
|
|
59.6 |
|
|
60.9 |
|
|
|
61.6 |
|
62.1 |
|
|
|
64.1 |
|
|
|
64.6 |
|
|
|
64.5 |
|
|
66.6 |
|
|
|
68.5 |
|
|
|
|
68.1 |
Terminal Sacrifice |
99 |
99 |
62.5mg/kg |
616 |
23.4 |
24.3 |
25.6 |
27.2 |
28.1 |
29.3 |
30.6 |
32.7 |
33.5 |
34.1 |
36.4 |
35.7 |
40.4 |
|
43.9 |
45.7 |
46.5 |
50.7 |
50.9 |
50.6 |
52.1 |
53 |
|
54.1 |
|
54.6 |
54.5 |
|
55.5 |
|
|
56.3 |
|
|
56.1 |
|
|
|
58.7 |
|
59.3 |
|
|
|
60 |
|
|
|
60.2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
100 |
100 |
62.5mg/kg |
730 |
24 |
25.2 |
26.5 |
26.9 |
29.1 |
28.4 |
30.8 |
31.6 |
33 |
32.6 |
34.6 |
34.6 |
38 |
|
39.5 |
43.4 |
44.2 |
47.9 |
46.5 |
49.9 |
53.4 |
52.4 |
|
54.7 |
|
53.7 |
53.5 |
|
54.7 |
|
|
54.5 |
|
|
55.3 |
|
|
|
54.8 |
|
55.9 |
|
|
|
56.9 |
|
|
|
57.2 |
|
|
|
56.7 |
|
|
56.8 |
|
|
|
57.2 |
|
|
|
|
55.6 |
Terminal Sacrifice |
101 |
101 |
125mg/kg |
610 |
25.1 |
25.8 |
27.4 |
29.8 |
31 |
31.2 |
32.8 |
34.8 |
34 |
35.9 |
38.4 |
37.1 |
39.8 |
|
44.8 |
48.5 |
49 |
53.2 |
52.1 |
51.7 |
53.1 |
52.9 |
|
50 |
|
44.6 |
41.5 |
|
39.7 |
|
|
38.1 |
|
|
37.6 |
|
|
|
38 |
|
36.3 |
|
|
|
33 |
|
|
31.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
102 |
102 |
125mg/kg |
686 |
23.3 |
24.1 |
25.7 |
26.7 |
28.3 |
28.1 |
30 |
32.3 |
33.3 |
34.3 |
37.2 |
36.3 |
40.6 |
|
42.4 |
45.4 |
48.7 |
51.7 |
51 |
51.8 |
51.4 |
51.1 |
|
52.3 |
|
52 |
52.1 |
|
52.4 |
|
|
53.2 |
|
|
53.2 |
|
|
|
53.6 |
|
50.2 |
|
|
|
44.6 |
|
|
|
38.6 |
|
|
|
34.1 |
|
|
30.4 |
|
29.3 |
|
|
|
|
|
|
|
Natural Death |
103 |
103 |
125mg/kg |
637 |
23.2 |
24.2 |
26.5 |
27.6 |
30.2 |
30.8 |
31.9 |
33.5 |
32.7 |
34.1 |
35.7 |
35.5 |
38.8 |
|
41.2 |
44.7 |
48.4 |
51.3 |
51 |
52 |
50.9 |
51.7 |
|
52.2 |
|
51.4 |
50.4 |
|
48.8 |
|
|
42.2 |
|
|
38.3 |
|
|
|
34.8 |
|
32.6 |
|
|
|
28.3 |
|
|
|
26 |
|
|
23.6 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
104 |
104 |
125mg/kg |
731 |
23.1 |
24 |
26.3 |
26.9 |
29.5 |
31.2 |
32.5 |
34 |
33 |
33.7 |
35.5 |
34.2 |
38.7 |
|
43.4 |
44.9 |
45.5 |
51.3 |
51.9 |
54 |
53.8 |
54.1 |
|
55.2 |
|
55.5 |
55.3 |
|
54.6 |
|
|
56.3 |
|
|
57.8 |
|
|
|
57.6 |
|
58.4 |
|
|
|
58.9 |
|
|
|
59.2 |
|
|
|
60.5 |
|
|
62 |
|
|
|
61.1 |
|
|
|
|
61.9 |
Terminal Sacrifice |
105 |
105 |
125mg/kg |
717 |
23.6 |
24.7 |
26.9 |
28 |
30 |
31.9 |
33.8 |
34.8 |
34.4 |
36 |
38 |
37.7 |
42.4 |
|
48.4 |
51.1 |
52.2 |
54.6 |
53.7 |
54.9 |
58.9 |
57.4 |
|
57.2 |
|
58.1 |
58.5 |
|
59.3 |
|
|
59.5 |
|
|
60.2 |
|
|
|
60.5 |
|
53.3 |
|
|
|
51.5 |
|
|
|
53 |
|
|
|
50.3 |
|
|
49.7 |
|
|
|
45 |
|
|
34.3 |
|
|
Moribund Sacrifice |
106 |
106 |
125mg/kg |
731 |
23.4 |
24.1 |
26.3 |
27.9 |
30.6 |
32.2 |
35.3 |
37.9 |
39 |
41 |
41.7 |
42.9 |
47.6 |
|
49.9 |
51.8 |
51.8 |
54.2 |
56.3 |
55.9 |
60.6 |
60.5 |
|
60.6 |
|
60.7 |
60.5 |
|
61.2 |
|
|
60.6 |
|
|
52.4 |
|
|
|
39.8 |
|
40.4 |
|
|
|
43.9 |
|
|
|
40.9 |
|
|
|
41.4 |
|
|
39.6 |
|
|
|
38.6 |
|
|
|
|
34.2 |
Terminal Sacrifice |
107 |
107 |
125mg/kg |
731 |
23.2 |
23.9 |
25.9 |
25.5 |
27.5 |
27.9 |
30.6 |
32.2 |
30.9 |
32.6 |
34.4 |
34.2 |
36.9 |
|
40.3 |
42.7 |
44.1 |
48.6 |
48.9 |
50.8 |
53 |
54.5 |
|
55.4 |
|
51.3 |
51.4 |
|
51.8 |
|
|
49.2 |
|
|
50.2 |
|
|
|
50.1 |
|
48 |
|
|
|
45.8 |
|
|
|
44 |
|
|
|
41.8 |
|
|
38.2 |
|
|
|
37.5 |
|
|
|
|
37 |
Terminal Sacrifice |
108 |
108 |
125mg/kg |
731 |
24.4 |
25.1 |
26.4 |
27.7 |
29.4 |
30.3 |
30.9 |
31.9 |
32.7 |
33.5 |
35.4 |
35.4 |
39.9 |
|
42.7 |
46.3 |
50.1 |
52.5 |
51.6 |
51.8 |
53.4 |
53.1 |
|
55.5 |
|
55.1 |
56.2 |
|
55.8 |
|
|
54.4 |
|
|
53.1 |
|
|
|
51.7 |
|
48.8 |
|
|
|
45.1 |
|
|
|
40.3 |
|
|
|
37.4 |
|
|
38 |
|
|
|
37.2 |
|
|
|
|
36.5 |
Terminal Sacrifice |
109 |
109 |
125mg/kg |
731 |
23.4 |
23.5 |
24.8 |
25 |
26.7 |
27.2 |
28.7 |
29.9 |
30.8 |
31.1 |
30.9 |
31.9 |
35.8 |
|
38.1 |
41.4 |
43.9 |
47.2 |
49.6 |
50.4 |
52.4 |
52.2 |
|
52.3 |
|
50.7 |
50.5 |
|
50.4 |
|
|
49.7 |
|
|
47.3 |
|
|
|
43.1 |
|
38.5 |
|
|
|
37.2 |
|
|
|
33.6 |
|
|
|
32.9 |
|
|
30.8 |
|
|
|
28.4 |
|
|
|
|
27.5 |
Terminal Sacrifice |
110 |
110 |
125mg/kg |
133 |
25.4 |
25.7 |
28 |
28.9 |
30.7 |
30.7 |
31.9 |
33.3 |
32.9 |
33 |
35.6 |
36.7 |
39.6 |
34.4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Dosing Accident |
111 |
111 |
125mg/kg |
730 |
22.1 |
22.5 |
24 |
24.3 |
25.8 |
26.9 |
28.3 |
29.1 |
29.5 |
29.9 |
32.1 |
31.9 |
35.8 |
|
36.7 |
40.4 |
43.4 |
46.8 |
49.5 |
49.1 |
51.4 |
49.5 |
|
50.6 |
|
51.3 |
50.6 |
|
49.2 |
|
|
50.3 |
|
|
48 |
|
|
|
48.1 |
|
43.8 |
|
|
|
40.7 |
|
|
|
36.9 |
|
|
|
35.9 |
|
|
35.1 |
|
|
|
35.8 |
|
|
|
|
34.7 |
Terminal Sacrifice |
112 |
112 |
125mg/kg |
732 |
24.8 |
26.4 |
29.4 |
30.3 |
32.1 |
33.2 |
35.5 |
36.8 |
36.3 |
38 |
39.8 |
41.3 |
45.6 |
|
49.4 |
51.6 |
52.9 |
54.3 |
54.8 |
54.6 |
58.1 |
57.9 |
|
57.9 |
|
60.7 |
61.3 |
|
60.4 |
|
|
61.4 |
|
|
61.7 |
|
|
|
61.6 |
|
62.4 |
|
|
|
63.3 |
|
|
|
63.3 |
|
|
|
62.7 |
|
|
62.3 |
|
|
|
59.3 |
|
|
|
|
55.6 |
Terminal Sacrifice |
113 |
113 |
125mg/kg |
596 |
24.8 |
25 |
27.1 |
28.1 |
30.1 |
31.1 |
33.4 |
35.2 |
35.9 |
37.4 |
38.7 |
39.2 |
44.2 |
|
47.7 |
49.8 |
50.8 |
53.1 |
53.3 |
53.7 |
57.9 |
57.4 |
|
58.2 |
|
59.3 |
59.7 |
|
59.2 |
|
|
59.9 |
|
|
60 |
|
|
|
59 |
|
58.5 |
|
|
|
60.8 |
58.9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
114 |
114 |
125mg/kg |
730 |
25.1 |
26.4 |
29.1 |
29.7 |
32.7 |
33.9 |
34.6 |
36.3 |
34.2 |
36.6 |
38.7 |
38.7 |
43.4 |
|
48.1 |
52.1 |
52.8 |
53.7 |
53.6 |
53.1 |
57 |
57.3 |
|
58.9 |
|
58.8 |
58.8 |
|
57.7 |
|
|
61.5 |
|
|
63.7 |
|
|
|
62.4 |
|
62.8 |
|
|
|
63.8 |
|
|
|
64 |
|
|
|
63.7 |
|
|
53.3 |
|
|
|
53.9 |
|
|
|
|
48 |
Terminal Sacrifice |
115 |
115 |
125mg/kg |
732 |
23.4 |
23.7 |
24.5 |
25.3 |
26.5 |
27.8 |
28.4 |
30.1 |
30.6 |
30.7 |
32.8 |
32.7 |
36.3 |
|
40 |
42.6 |
46.4 |
49.8 |
51.7 |
50.9 |
51 |
52.6 |
|
53.9 |
|
47.4 |
54.4 |
|
56.6 |
|
|
57.2 |
|
|
56.4 |
|
|
|
57.6 |
|
57.3 |
|
|
|
58 |
|
|
|
57.7 |
|
|
|
58.8 |
|
|
58.5 |
|
|
|
59 |
|
|
|
|
57.7 |
Terminal Sacrifice |
116 |
116 |
125mg/kg |
732 |
23 |
24.2 |
25.6 |
26.6 |
28 |
29.1 |
31.6 |
32.6 |
34 |
34.4 |
35.9 |
36.6 |
39.9 |
|
42.7 |
45.1 |
47.8 |
51.8 |
53.5 |
55.2 |
54.4 |
55.7 |
|
56.9 |
|
56.7 |
57.9 |
|
59.1 |
|
|
60.4 |
|
|
60.7 |
|
|
|
61 |
|
60.4 |
|
|
|
63.1 |
|
|
|
64.9 |
|
|
|
65.1 |
|
|
66.3 |
|
|
|
66.2 |
|
|
|
|
67.2 |
Terminal Sacrifice |
117 |
117 |
125mg/kg |
731 |
25.1 |
25.6 |
27.8 |
28.1 |
30 |
30.8 |
32.6 |
34.1 |
35 |
36.1 |
38.8 |
38.2 |
42.6 |
|
44.6 |
50.5 |
52.6 |
52.3 |
53.5 |
53.8 |
54.3 |
55.4 |
|
56.1 |
|
55.3 |
56.9 |
|
57.7 |
|
|
58.7 |
|
|
56.1 |
|
|
|
57.6 |
|
57 |
|
|
|
57.5 |
|
|
|
56.1 |
|
|
|
53.7 |
|
|
51.6 |
|
|
|
49.1 |
|
|
|
|
46.2 |
Terminal Sacrifice |
118 |
118 |
125mg/kg |
655 |
25.9 |
26.4 |
28.7 |
28.8 |
30.8 |
31.5 |
32.9 |
34.5 |
34.6 |
36.5 |
37.7 |
38 |
41.8 |
|
46.4 |
48.5 |
51.9 |
53.4 |
53.8 |
54.4 |
55.1 |
54.7 |
|
56.7 |
|
57.1 |
56.8 |
|
54.3 |
|
|
54.8 |
|
|
54.4 |
|
|
|
50.9 |
|
47 |
|
|
|
43.1 |
|
|
|
38.9 |
|
|
|
35.2 |
33 |
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
119 |
119 |
125mg/kg |
716 |
23.1 |
23.6 |
24.5 |
25 |
26.6 |
28.2 |
29.5 |
30.9 |
29.6 |
30.2 |
33 |
33 |
37.6 |
|
40.7 |
43.8 |
45.9 |
50.6 |
51.7 |
51.4 |
52.9 |
53.6 |
|
55.1 |
|
54.7 |
53.8 |
|
53.6 |
|
|
53.1 |
|
|
52.1 |
|
|
|
49.4 |
|
44.3 |
|
|
|
38.6 |
|
|
|
35.5 |
|
|
|
34.2 |
|
|
35.7 |
|
|
|
35.7 |
|
|
35 |
|
|
Moribund Sacrifice |
120 |
120 |
125mg/kg |
732 |
24.5 |
24.7 |
27.2 |
28.5 |
30.1 |
32.3 |
33.4 |
35.7 |
35.8 |
37.8 |
39.7 |
39 |
42.2 |
|
45.8 |
49.2 |
51.2 |
54.7 |
53.7 |
54 |
57.2 |
56.1 |
|
56.6 |
|
57.9 |
58.6 |
|
59.5 |
|
|
60.9 |
|
|
61 |
|
|
|
60.8 |
|
61.4 |
|
|
|
61.3 |
|
|
|
61.1 |
|
|
|
58.6 |
|
|
58.9 |
|
|
|
53.9 |
|
|
|
|
51 |
Terminal Sacrifice |
121 |
121 |
125mg/kg |
732 |
24.2 |
24.7 |
26.1 |
27.1 |
29.4 |
30.6 |
31.2 |
32.6 |
33.4 |
34.7 |
36.5 |
36.3 |
38.9 |
|
42.3 |
44.6 |
45.6 |
50.4 |
52.1 |
54.2 |
55.2 |
55.9 |
|
56.3 |
|
55.9 |
56.9 |
|
58.2 |
|
|
59.3 |
|
|
59.2 |
|
|
|
59.9 |
|
58.9 |
|
|
|
59 |
|
|
|
59.7 |
|
|
|
60.4 |
|
|
60.2 |
|
|
|
57.4 |
|
|
|
|
59.8 |
Terminal Sacrifice |
122 |
122 |
125mg/kg |
732 |
23.1 |
23.6 |
24.7 |
26.1 |
27.7 |
28.8 |
29.4 |
32.2 |
33.2 |
33.8 |
35.1 |
36.3 |
40.5 |
|
43.6 |
50.2 |
52 |
52.8 |
53.6 |
53.8 |
56.3 |
57.1 |
|
56.9 |
|
56.9 |
56.7 |
|
57.7 |
|
|
56.8 |
|
|
56.2 |
|
|
|
55.8 |
|
50.5 |
|
|
|
45.7 |
|
|
|
46.6 |
|
|
|
45.1 |
|
|
42.3 |
|
|
|
41.2 |
|
|
|
|
39.7 |
Terminal Sacrifice |
123 |
123 |
125mg/kg |
437 |
25.4 |
25.6 |
27 |
27.2 |
30.2 |
31 |
32.2 |
33.2 |
34.8 |
35.7 |
37.3 |
37.5 |
43.3 |
|
47.1 |
51.1 |
52.2 |
52.7 |
54.9 |
54.1 |
56 |
56.5 |
|
57.6 |
|
58.2 |
57.8 |
58.3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
124 |
124 |
125mg/kg |
732 |
23.8 |
24.5 |
25.6 |
26.6 |
27.6 |
27.8 |
29.5 |
30 |
30.7 |
31.1 |
31.7 |
31.6 |
35 |
|
35.9 |
36.3 |
38.2 |
40.5 |
39.7 |
43.2 |
46 |
47.9 |
|
49.1 |
|
51.8 |
51.2 |
|
48.9 |
|
|
52.3 |
|
|
53.1 |
|
|
|
55.3 |
|
57.7 |
|
|
|
56.4 |
|
|
|
47.3 |
|
|
|
55.2 |
|
|
56.5 |
|
|
|
56.2 |
|
|
|
|
58.8 |
Terminal Sacrifice |
125 |
125 |
125mg/kg |
731 |
24 |
24.7 |
26.3 |
27.2 |
28.3 |
29.5 |
30.7 |
32.5 |
33.5 |
34 |
35.2 |
35.9 |
40.8 |
|
45.2 |
48.6 |
49.8 |
51.4 |
51.1 |
50.9 |
53 |
52.6 |
|
53.9 |
|
54.6 |
55 |
|
54.6 |
|
|
54.7 |
|
|
54.2 |
|
|
|
54.8 |
|
54.8 |
|
|
|
55.5 |
|
|
|
55.9 |
|
|
|
55.1 |
|
|
55.7 |
|
|
|
55.7 |
|
|
|
|
54.3 |
Terminal Sacrifice |
126 |
126 |
125mg/kg |
732 |
26.6 |
27.4 |
28.9 |
29.8 |
32 |
32.8 |
33.8 |
35.6 |
36 |
36.8 |
38.7 |
39.7 |
45 |
|
49.5 |
53 |
53.1 |
54.5 |
54.8 |
54.9 |
59 |
57.5 |
|
52.5 |
|
57.8 |
57.5 |
|
60.2 |
|
|
59.5 |
|
|
60.5 |
|
|
|
61.5 |
|
61.1 |
|
|
|
61.3 |
|
|
|
62.1 |
|
|
|
62.4 |
|
|
63.3 |
|
|
|
63.6 |
|
|
|
|
56.2 |
Terminal Sacrifice |
127 |
127 |
125mg/kg |
731 |
24.3 |
24.9 |
26.4 |
27.6 |
29 |
29.4 |
31.1 |
31.8 |
31.8 |
33.9 |
35.3 |
34.9 |
39 |
|
41.1 |
43.7 |
45.4 |
48.7 |
51.6 |
50.9 |
55.1 |
54.5 |
|
56.4 |
|
56.5 |
55.7 |
|
56.4 |
|
|
57.3 |
|
|
57.3 |
|
|
|
57.4 |
|
57.5 |
|
|
|
59 |
|
|
|
58.7 |
|
|
|
59.7 |
|
|
61 |
|
|
|
62.3 |
|
|
|
|
59 |
Terminal Sacrifice |
128 |
128 |
125mg/kg |
598 |
25.2 |
26.4 |
28 |
29.7 |
31.4 |
30.9 |
31.4 |
33.7 |
33.2 |
35.1 |
36.5 |
35.6 |
39.5 |
|
42.5 |
46 |
48.6 |
50.8 |
51.4 |
51.1 |
52.5 |
52.9 |
|
54.5 |
|
55.4 |
54.2 |
|
55.5 |
|
|
56.1 |
|
|
56.4 |
|
|
|
57.3 |
|
56.2 |
|
|
|
52.7 |
|
50.8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
129 |
129 |
125mg/kg |
731 |
23.6 |
24.9 |
27.5 |
27.4 |
29.1 |
29.9 |
30.8 |
30 |
31.1 |
33 |
36.6 |
35.6 |
41.4 |
|
43.3 |
44.7 |
47 |
50.1 |
51.7 |
52.9 |
51.3 |
52.3 |
|
53.7 |
|
54.4 |
54.7 |
|
56.1 |
|
|
56.3 |
|
|
56 |
|
|
|
57.4 |
|
57.6 |
|
|
|
58.1 |
|
|
|
58.7 |
|
|
|
56.7 |
|
|
55.5 |
|
|
|
53.3 |
|
|
|
|
50.4 |
Terminal Sacrifice |
130 |
130 |
125mg/kg |
637 |
23.7 |
24.1 |
25.7 |
25.5 |
27.3 |
27.6 |
29.7 |
31 |
32.8 |
33.4 |
35 |
36.7 |
40.4 |
|
42.9 |
44.9 |
48.2 |
52.6 |
52 |
52.8 |
54.2 |
53.2 |
|
54.3 |
|
54.9 |
55.3 |
|
55.5 |
|
|
56.7 |
|
|
56.5 |
|
|
|
56.6 |
|
58 |
|
|
|
58.2 |
|
|
|
53.6 |
|
|
53.3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
131 |
131 |
125mg/kg |
617 |
23.4 |
23.8 |
25.5 |
26 |
28.7 |
28.5 |
30.3 |
31.7 |
31.8 |
32.3 |
34.5 |
33.8 |
38.8 |
|
41 |
45.1 |
48.3 |
51.1 |
51.4 |
53.1 |
52.6 |
51.7 |
|
52 |
|
52 |
50.9 |
|
51.1 |
|
|
50 |
|
|
49.5 |
|
|
|
45.5 |
|
39.4 |
|
|
|
36 |
|
|
|
32.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
132 |
132 |
125mg/kg |
732 |
25 |
26.1 |
27 |
27.5 |
28.8 |
30.2 |
30.8 |
33.4 |
34.8 |
34.4 |
36.6 |
35.7 |
42.2 |
|
46.2 |
51 |
51.9 |
54 |
54.5 |
54.6 |
56.5 |
56.5 |
|
57.7 |
|
58.2 |
58.7 |
|
59.8 |
|
|
61.2 |
|
|
61.4 |
|
|
|
61.7 |
|
61.5 |
|
|
|
61.7 |
|
|
|
59.5 |
|
|
|
61.7 |
|
|
61 |
|
|
|
58.1 |
|
|
|
|
57.1 |
Terminal Sacrifice |
133 |
133 |
125mg/kg |
732 |
23.3 |
23.7 |
24.5 |
25.4 |
27.1 |
27.8 |
29.8 |
30.7 |
30.6 |
30.9 |
32.8 |
32.2 |
39.4 |
|
42.4 |
45.5 |
49.3 |
51.5 |
52.2 |
52.3 |
54 |
52.4 |
|
54.5 |
|
55.7 |
55.4 |
|
55.8 |
|
|
55.8 |
|
|
56.1 |
|
|
|
55.9 |
|
56.4 |
|
|
|
57.4 |
|
|
|
56.2 |
|
|
|
54.1 |
|
|
53.3 |
|
|
|
54.3 |
|
|
|
|
53.9 |
Terminal Sacrifice |
134 |
134 |
125mg/kg |
580 |
24 |
23.7 |
26.8 |
26.5 |
29 |
29.5 |
30.2 |
32.9 |
33.2 |
33.5 |
35.8 |
35.7 |
40.7 |
|
43.4 |
46.5 |
49.1 |
53.2 |
52.4 |
53 |
54.6 |
53.3 |
|
55.1 |
|
56.8 |
58.9 |
|
59.2 |
|
|
60.1 |
|
|
60.9 |
|
|
|
61.6 |
|
61.1 |
|
|
61.4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
135 |
135 |
125mg/kg |
655 |
25.6 |
26.9 |
30.5 |
32.4 |
33.8 |
35.6 |
36.2 |
37.9 |
38.4 |
40.4 |
43.3 |
43.4 |
49.6 |
|
53.3 |
54.6 |
54.4 |
56.5 |
56.5 |
56.8 |
58.8 |
58.7 |
|
59.1 |
|
59.6 |
61.5 |
|
60.9 |
|
|
60.7 |
|
|
55.6 |
|
|
|
48.6 |
|
46.1 |
|
|
|
45.4 |
|
|
|
43.3 |
|
|
|
40.3 |
35.4 |
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
136 |
136 |
125mg/kg |
702 |
25.1 |
25.5 |
27.4 |
28.5 |
30.4 |
31.5 |
33.4 |
35.4 |
37 |
39.1 |
41.7 |
42.1 |
49.2 |
|
53.9 |
55.5 |
55 |
58.8 |
60.6 |
60.4 |
63.4 |
65 |
|
67.6 |
|
66.2 |
66 |
|
66.3 |
|
|
64.4 |
|
|
59.2 |
|
|
|
56.4 |
|
52.5 |
|
|
|
50.7 |
|
|
|
47.7 |
|
|
|
38.7 |
|
|
42.5 |
|
|
|
46.3 |
47.9 |
|
|
|
|
Moribund Sacrifice |
137 |
137 |
125mg/kg |
730 |
25.3 |
25.9 |
28 |
28.1 |
31.1 |
32.7 |
33.4 |
35.3 |
34.7 |
35.9 |
37.6 |
38 |
35.3 |
|
45.6 |
49.4 |
51.9 |
55.1 |
54.2 |
54.7 |
54.6 |
56.5 |
|
58.4 |
|
58.8 |
58.5 |
|
59.3 |
|
|
62 |
|
|
61.1 |
|
|
|
61.6 |
|
63 |
|
|
|
61.6 |
|
|
|
54 |
|
|
|
56.2 |
|
|
55.1 |
|
|
|
52.4 |
|
|
|
|
45 |
Terminal Sacrifice |
138 |
138 |
125mg/kg |
731 |
25.6 |
26 |
27.6 |
28.1 |
29.8 |
30.7 |
32.7 |
33.2 |
33.9 |
35.2 |
36.4 |
37 |
42.4 |
|
45.6 |
48.8 |
50.8 |
51.9 |
51.1 |
52 |
53.8 |
54.1 |
|
54.7 |
|
56 |
55.9 |
|
56.5 |
|
|
56.7 |
|
|
57.4 |
|
|
|
59 |
|
59.1 |
|
|
|
60.4 |
|
|
|
59.3 |
|
|
|
58.9 |
|
|
51.9 |
|
|
|
47 |
|
|
|
|
43 |
Terminal Sacrifice |
139 |
139 |
125mg/kg |
695 |
22 |
22.8 |
23.6 |
24.4 |
25.7 |
26.9 |
29.4 |
30.5 |
30.4 |
32 |
33.9 |
34.9 |
39.6 |
|
43.8 |
49.1 |
49.6 |
51.1 |
51.7 |
52 |
53.3 |
52.9 |
|
53.9 |
|
53.6 |
53.4 |
|
54.1 |
|
|
53.8 |
|
|
55.1 |
|
|
|
56.8 |
|
56.2 |
|
|
|
54.3 |
|
|
|
51.4 |
|
|
|
47.6 |
|
|
45 |
|
|
|
38.2 |
|
|
|
|
|
Natural Death |
140 |
140 |
125mg/kg |
731 |
24.1 |
25.2 |
26.3 |
27.5 |
29.8 |
30.2 |
32.9 |
33.9 |
34.3 |
35.1 |
36 |
36.4 |
41 |
|
43.6 |
45.8 |
44.5 |
52.8 |
53.3 |
52.5 |
55.1 |
55 |
|
55.5 |
|
54.7 |
55.3 |
|
56.7 |
|
|
57.5 |
|
|
58 |
|
|
|
59.3 |
|
59.3 |
|
|
|
60 |
|
|
|
60 |
|
|
|
61.5 |
|
|
62.6 |
|
|
|
63.8 |
|
|
|
|
65 |
Terminal Sacrifice |
141 |
141 |
125mg/kg |
732 |
23.1 |
24.5 |
26.2 |
27.4 |
28.7 |
29.9 |
32.5 |
31.8 |
32 |
33.6 |
36.3 |
37.1 |
41.1 |
|
44.1 |
47.4 |
49.5 |
52.2 |
52.4 |
53.3 |
55.2 |
55.7 |
|
56.3 |
|
56.7 |
57.6 |
|
58.3 |
|
|
59.1 |
|
|
58.8 |
|
|
|
60.6 |
|
60.1 |
|
|
|
61.7 |
|
|
|
60.8 |
|
|
|
57.5 |
|
|
62 |
|
|
|
61.4 |
|
|
|
|
62.5 |
Terminal Sacrifice |
142 |
142 |
125mg/kg |
731 |
22.8 |
23.4 |
25.4 |
26.3 |
27.7 |
28.1 |
30 |
31 |
32.1 |
32.1 |
34.7 |
35.7 |
40.3 |
|
43 |
47.6 |
49.9 |
52.7 |
52.3 |
52.4 |
53.3 |
54.5 |
|
55.2 |
|
55.4 |
56.4 |
|
57.8 |
|
|
58.7 |
|
|
59.1 |
|
|
|
58.8 |
|
59 |
|
|
|
59.2 |
|
|
|
59.9 |
|
|
|
59.6 |
|
|
60.2 |
|
|
|
61.4 |
|
|
|
|
60.1 |
Terminal Sacrifice |
143 |
143 |
125mg/kg |
697 |
22.9 |
23.9 |
25.3 |
26.8 |
28.2 |
29 |
30.4 |
31.7 |
32.6 |
33.1 |
35.7 |
35.9 |
39.9 |
|
44.5 |
46.7 |
48.2 |
53 |
52.5 |
52.8 |
55.6 |
56 |
|
57.8 |
|
57.7 |
58.5 |
|
59.3 |
|
|
59.6 |
|
|
60.5 |
|
|
|
61.8 |
|
63.1 |
|
|
|
63.6 |
|
|
|
64.7 |
|
|
|
61.9 |
|
|
61 |
|
|
|
48.5 |
|
|
|
|
|
Moribund Sacrifice |
144 |
144 |
125mg/kg |
732 |
26.1 |
27.4 |
29.7 |
31.1 |
32.3 |
34.3 |
34.5 |
36.6 |
37.9 |
37.4 |
40 |
38.9 |
43.8 |
|
46.7 |
49.6 |
50 |
53.8 |
53.4 |
55.6 |
56.7 |
55.4 |
|
57.5 |
|
58.2 |
57.4 |
|
59 |
|
|
60.1 |
|
|
60.2 |
|
|
|
61.5 |
|
62.2 |
|
|
|
62.9 |
|
|
|
63.4 |
|
|
|
63.3 |
|
|
61.7 |
|
|
|
58 |
|
|
|
|
51.4 |
Terminal Sacrifice |
145 |
145 |
125mg/kg |
567 |
23.1 |
23.9 |
26.7 |
27 |
29.6 |
31.1 |
32.6 |
34.6 |
34.1 |
35.7 |
38.1 |
38.3 |
43.1 |
|
46.9 |
49 |
51.5 |
53.7 |
53.7 |
53.4 |
54.4 |
51.2 |
|
48.7 |
|
46.5 |
44.8 |
|
44.5 |
|
|
38.9 |
|
|
38.9 |
|
|
|
37.4 |
|
29.5 |
27.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
146 |
146 |
125mg/kg |
732 |
22.2 |
22.5 |
24.5 |
24.4 |
26.1 |
26.1 |
28.1 |
29.4 |
29.9 |
30.7 |
32.8 |
31.6 |
35.5 |
|
38.6 |
39.2 |
41.7 |
45.6 |
48.3 |
51.1 |
52.6 |
52.5 |
|
54.2 |
|
54.6 |
54.8 |
|
52.8 |
|
|
55.2 |
|
|
55.8 |
|
|
|
56 |
|
56.2 |
|
|
|
58.2 |
|
|
|
57.2 |
|
|
|
57.5 |
|
|
58.8 |
|
|
|
59.1 |
|
|
|
|
60 |
Terminal Sacrifice |
147 |
147 |
125mg/kg |
731 |
22.7 |
23.7 |
25.3 |
25.9 |
28.6 |
29.6 |
30.3 |
32.2 |
32 |
32.9 |
35.3 |
35.2 |
39.2 |
|
42.2 |
45.5 |
48.7 |
50.9 |
51.2 |
51.1 |
51.6 |
52.5 |
|
53.4 |
|
53.4 |
53.2 |
|
53.6 |
|
|
54.7 |
|
|
48.6 |
|
|
|
54.5 |
|
54.7 |
|
|
|
55.6 |
|
|
|
56.1 |
|
|
|
54.9 |
|
|
55.2 |
|
|
|
56.8 |
|
|
|
|
57.6 |
Terminal Sacrifice |
148 |
148 |
125mg/kg |
731 |
25.3 |
27.3 |
29.1 |
30.7 |
32.8 |
32.7 |
33.5 |
36.7 |
38.1 |
38.5 |
40.8 |
40.3 |
45.8 |
|
50.2 |
52.9 |
51.8 |
54.8 |
54.2 |
54.7 |
57.8 |
57.8 |
|
57.7 |
|
58.3 |
60 |
|
60.1 |
|
|
60.5 |
|
|
61.1 |
|
|
|
62.4 |
|
63 |
|
|
|
64.1 |
|
|
|
62.3 |
|
|
|
60.7 |
|
|
59.2 |
|
|
|
56.8 |
|
|
|
|
55.5 |
Terminal Sacrifice |
149 |
149 |
125mg/kg |
732 |
24.6 |
25 |
26.7 |
27.8 |
30.3 |
30.1 |
30.9 |
31.5 |
34.2 |
34.4 |
37.7 |
37 |
39 |
|
40.3 |
42.7 |
48.7 |
52.5 |
53.9 |
55.4 |
54.7 |
55 |
|
57.1 |
|
56.5 |
56.9 |
|
58.3 |
|
|
59.4 |
|
|
60.3 |
|
|
|
62 |
|
53 |
|
|
|
62.5 |
|
|
|
63.9 |
|
|
|
63.9 |
|
|
64.9 |
|
|
|
66.2 |
|
|
|
|
54.5 |
Terminal Sacrifice |
150 |
150 |
125mg/kg |
732 |
25.1 |
25 |
26.4 |
26.7 |
29 |
29 |
30.1 |
31.7 |
32.4 |
31.6 |
34.3 |
33.6 |
38.3 |
|
40.2 |
42.3 |
44 |
46.8 |
47.9 |
47.5 |
51.2 |
48.9 |
|
44.6 |
|
52.9 |
53.4 |
|
53.8 |
|
|
53.6 |
|
|
53.4 |
|
|
|
56.1 |
|
55.1 |
|
|
|
48.8 |
|
|
|
55.1 |
|
|
|
55.5 |
|
|
56.4 |
|
|
|
58 |
|
|
|
|
56.3 |
Terminal Sacrifice |
151 |
151 |
250mg/kg |
732 |
26.2 |
27.3 |
28 |
29.5 |
30.4 |
32.3 |
33.4 |
36 |
35.7 |
37 |
38.6 |
39.7 |
44.1 |
|
47.2 |
50 |
51.8 |
52.8 |
51.2 |
52.5 |
54.6 |
54.4 |
|
55.3 |
|
55.4 |
56.9 |
|
57.4 |
|
|
57.1 |
|
|
58.7 |
|
|
|
60 |
|
58.7 |
|
|
|
58.9 |
|
|
|
60.2 |
|
|
|
58.4 |
|
|
59.4 |
|
|
|
56.5 |
|
|
|
|
51.8 |
Terminal Sacrifice |
152 |
152 |
250mg/kg |
730 |
23.3 |
23.6 |
25 |
25.7 |
27 |
27.6 |
29.7 |
31.4 |
31.6 |
31.9 |
34 |
34.4 |
38.3 |
|
41.8 |
38.4 |
45.5 |
46.4 |
48.5 |
50.9 |
52.8 |
51.8 |
|
52.6 |
|
53.2 |
53.7 |
|
55.5 |
|
|
53.6 |
|
|
51.7 |
|
|
|
56.3 |
|
55.4 |
|
|
|
54.7 |
|
|
|
55.8 |
|
|
|
55 |
|
|
54.8 |
|
|
|
52.7 |
|
|
|
|
48.3 |
Terminal Sacrifice |
153 |
153 |
250mg/kg |
731 |
22.7 |
22.8 |
24.1 |
24.7 |
26 |
27.2 |
28.4 |
29.4 |
30.4 |
31.4 |
32.9 |
33.8 |
33.9 |
|
37 |
39.6 |
41.6 |
42.2 |
44.6 |
45.6 |
48 |
49 |
|
52.2 |
|
52.6 |
52 |
|
54.7 |
|
|
52.9 |
|
|
54.3 |
|
|
|
55.3 |
|
55.8 |
|
|
|
55.5 |
|
|
|
56.6 |
|
|
|
56.3 |
|
|
57.2 |
|
|
|
52.2 |
|
|
|
|
57.7 |
Terminal Sacrifice |
154 |
154 |
250mg/kg |
731 |
21.6 |
21.9 |
23.7 |
23.8 |
25 |
25.5 |
26 |
27.3 |
27.6 |
27.6 |
29.5 |
30.2 |
32.9 |
|
36.1 |
38.3 |
34.7 |
37.6 |
41.3 |
42.7 |
48.2 |
48.6 |
|
49.9 |
|
51.3 |
50.8 |
|
52.2 |
|
|
50.6 |
|
|
53.1 |
|
|
|
53.4 |
|
51.8 |
|
|
|
53 |
|
|
|
53.3 |
|
|
|
51.8 |
|
|
50.9 |
|
|
|
49.6 |
|
|
|
|
47.7 |
Terminal Sacrifice |
155 |
155 |
250mg/kg |
731 |
23.3 |
24.3 |
25.4 |
26.7 |
28.3 |
29.4 |
31.1 |
34.1 |
34.4 |
35.1 |
36.4 |
36.7 |
40.4 |
|
42.7 |
45.6 |
48.9 |
51.2 |
50.5 |
50.9 |
51.8 |
52.8 |
|
52.6 |
|
53.6 |
54 |
|
55.2 |
|
|
54.9 |
|
|
56 |
|
|
|
56.1 |
|
56.2 |
|
|
|
57.8 |
|
|
|
58.5 |
|
|
|
57.8 |
|
|
57.6 |
|
|
|
56.9 |
|
|
|
|
42.6 |
Terminal Sacrifice |
156 |
156 |
250mg/kg |
730 |
24.7 |
24.7 |
26 |
27.2 |
29.2 |
29.9 |
31.5 |
33.8 |
33.5 |
34.2 |
35.5 |
36.4 |
39.6 |
|
44.4 |
47 |
47.8 |
51.8 |
51.5 |
50.9 |
52.5 |
52.3 |
|
54.2 |
|
54.8 |
55.9 |
|
57.3 |
|
|
57.1 |
|
|
57.9 |
|
|
|
58.4 |
|
56.6 |
|
|
|
59.3 |
|
|
|
59.6 |
|
|
|
58.4 |
|
|
55.1 |
|
|
|
53.5 |
|
|
|
|
48 |
Terminal Sacrifice |
157 |
157 |
250mg/kg |
730 |
23.5 |
24.4 |
25.7 |
27.4 |
28.8 |
29.2 |
29.5 |
30.1 |
31.3 |
32.1 |
33.3 |
33.6 |
35.8 |
|
38.1 |
39.9 |
42.9 |
47.2 |
47.2 |
45.5 |
44.7 |
44.6 |
|
48.7 |
|
48.2 |
52.5 |
|
52.8 |
|
|
51.2 |
|
|
49.9 |
|
|
|
51.5 |
|
51.6 |
|
|
|
54 |
|
|
|
52.5 |
|
|
|
53.7 |
|
|
54.8 |
|
|
|
55.3 |
|
|
|
|
51.6 |
Terminal Sacrifice |
158 |
158 |
250mg/kg |
721 |
23.6 |
24.2 |
25.4 |
25.6 |
27.2 |
28 |
28.9 |
31 |
30.9 |
31.9 |
33.3 |
34.4 |
36.3 |
|
38 |
41.9 |
42.9 |
45.6 |
48.4 |
50.5 |
52.9 |
53.7 |
|
55.9 |
|
56.3 |
55.8 |
|
56 |
|
|
55.6 |
|
|
55.9 |
|
|
|
57.1 |
|
57.4 |
|
|
|
56.8 |
|
|
|
58 |
|
|
|
58.3 |
|
|
56.5 |
|
|
|
55.3 |
|
|
39.9 |
|
|
Moribund Sacrifice |
159 |
159 |
250mg/kg |
732 |
23.7 |
25 |
26.3 |
27.6 |
29.7 |
29.7 |
31.7 |
33.1 |
34.6 |
34.7 |
37.6 |
36.7 |
41.5 |
|
43.2 |
46.8 |
47.3 |
50.9 |
53.1 |
55 |
57.6 |
56.1 |
|
57.7 |
|
57.7 |
57.5 |
|
59.8 |
|
|
60.5 |
|
|
61.6 |
|
|
|
62.5 |
|
63.3 |
|
|
|
64.5 |
|
|
|
63.6 |
|
|
|
64.2 |
|
|
62.5 |
|
|
|
58.7 |
|
|
|
|
59.1 |
Terminal Sacrifice |
160 |
160 |
250mg/kg |
732 |
23.4 |
24 |
24.8 |
26.2 |
28 |
27.7 |
29.3 |
30.5 |
30.5 |
31.2 |
33.2 |
32.9 |
35.6 |
|
37.4 |
40.6 |
41.3 |
44.2 |
45.6 |
47.7 |
49.8 |
49.3 |
|
52.9 |
|
52.2 |
52.6 |
|
53.5 |
|
|
52.6 |
|
|
52.9 |
|
|
|
53.7 |
|
53.1 |
|
|
|
53.4 |
|
|
|
51.9 |
|
|
|
50.1 |
|
|
49.4 |
|
|
|
46.6 |
|
|
|
|
43.7 |
Terminal Sacrifice |
161 |
161 |
250mg/kg |
732 |
22.9 |
23.1 |
25.6 |
25.6 |
26.5 |
27.7 |
28 |
29.8 |
31.1 |
30.7 |
32.5 |
32.1 |
37.7 |
|
40.3 |
41.8 |
44.8 |
49.4 |
49.6 |
50.8 |
51.6 |
50.7 |
|
51.3 |
|
51.3 |
51.4 |
|
51.3 |
|
|
52.5 |
|
|
51 |
|
|
|
48.4 |
|
45 |
|
|
|
40.7 |
|
|
|
38.4 |
|
|
|
35.7 |
|
|
33.6 |
|
|
|
33.1 |
|
|
|
|
33.7 |
Terminal Sacrifice |
162 |
162 |
250mg/kg |
732 |
24.2 |
25.3 |
27.7 |
27.6 |
29.4 |
30.3 |
31.8 |
33.7 |
36.2 |
36.5 |
38.6 |
38.2 |
43.3 |
|
46 |
48.9 |
50.3 |
51.8 |
51.6 |
52.4 |
54.1 |
54.5 |
|
55.3 |
|
55.1 |
56.2 |
|
56.8 |
|
|
56.5 |
|
|
57.4 |
|
|
|
57.3 |
|
56.8 |
|
|
|
55.5 |
|
|
|
49.1 |
|
|
|
42.9 |
|
|
39.2 |
|
|
|
39 |
|
|
|
|
39.3 |
Terminal Sacrifice |
163 |
163 |
250mg/kg |
731 |
24.9 |
25.2 |
27.2 |
28.2 |
30.4 |
31.5 |
33.6 |
35.4 |
35.7 |
37.8 |
39.2 |
39.4 |
39.8 |
|
44.7 |
47.7 |
49.4 |
52.2 |
51.7 |
52.5 |
52.4 |
52.8 |
|
54.3 |
|
53.5 |
53.6 |
|
54.8 |
|
|
54.2 |
|
|
55.2 |
|
|
|
56 |
|
55.5 |
|
|
|
56.2 |
|
|
|
55.4 |
|
|
|
54.2 |
|
|
46.6 |
|
|
|
41.5 |
|
|
|
|
36.2 |
Terminal Sacrifice |
164 |
164 |
250mg/kg |
731 |
24.9 |
26.9 |
29.4 |
30.3 |
32.8 |
33 |
35.1 |
36.9 |
37.7 |
38.8 |
40.2 |
40 |
44.7 |
|
46.1 |
51.3 |
52.6 |
54.6 |
53.9 |
56.1 |
56.5 |
56 |
|
56.4 |
|
56.4 |
56.9 |
|
56.5 |
|
|
56.3 |
|
|
56.9 |
|
|
|
55.8 |
|
52.5 |
|
|
|
52.6 |
|
|
|
50.2 |
|
|
|
47.8 |
|
|
43.9 |
|
|
|
40.8 |
|
|
|
|
39.9 |
Terminal Sacrifice |
165 |
165 |
250mg/kg |
732 |
25.6 |
26.4 |
28.9 |
29.1 |
31.4 |
33 |
33.9 |
36.2 |
36.5 |
38.4 |
40.6 |
40.5 |
45.5 |
|
47.5 |
51.2 |
51.5 |
51.9 |
52.2 |
52.1 |
54.1 |
54.4 |
|
55.5 |
|
54.3 |
55.6 |
|
56.1 |
|
|
57.3 |
|
|
57.2 |
|
|
|
58.1 |
|
59.1 |
|
|
|
59.5 |
|
|
|
57.2 |
|
|
|
54.9 |
|
|
53.3 |
|
|
|
49.1 |
|
|
|
|
46.7 |
Terminal Sacrifice |
166 |
166 |
250mg/kg |
694 |
24.6 |
25.1 |
25.5 |
25.7 |
26.7 |
27.5 |
29 |
30.5 |
31.6 |
31.5 |
33.4 |
32.6 |
37.1 |
|
39.5 |
41.7 |
43.7 |
47.6 |
48.8 |
51.1 |
52.6 |
50.2 |
|
53.7 |
|
54.7 |
51.7 |
|
49.8 |
|
|
48 |
|
|
48.2 |
|
|
|
45.7 |
|
40.3 |
|
|
|
38.7 |
|
|
|
36.7 |
|
|
|
33.3 |
|
|
30.9 |
|
|
27.3 |
|
|
|
|
|
|
Moribund Sacrifice |
167 |
167 |
250mg/kg |
730 |
23.2 |
24.1 |
25.7 |
26 |
27.4 |
28.7 |
29.2 |
30.8 |
31.9 |
32.6 |
34.4 |
33.5 |
39 |
|
40.6 |
45 |
46.8 |
50.4 |
51 |
51.9 |
52.7 |
52.8 |
|
47 |
|
54.2 |
54.5 |
|
56.2 |
|
|
56 |
|
|
56.6 |
|
|
|
57.6 |
|
47.8 |
|
|
|
58.4 |
|
|
|
58.8 |
|
|
|
58.4 |
|
|
58.6 |
|
|
|
56.7 |
|
|
|
|
53.7 |
Terminal Sacrifice |
168 |
168 |
250mg/kg |
653 |
22.9 |
23.8 |
25.2 |
25.6 |
27.7 |
27.4 |
28.7 |
31.2 |
30.5 |
31.7 |
34.3 |
33.7 |
39.3 |
|
41.3 |
44.2 |
46.7 |
49.4 |
49.5 |
52.5 |
53.7 |
51 |
|
52.1 |
|
52.5 |
52.3 |
|
52.3 |
|
|
51 |
|
|
48.5 |
|
|
|
44.1 |
|
40.2 |
|
|
|
35.9 |
|
|
|
33.9 |
|
|
|
26.6 |
24.7 |
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
169 |
169 |
250mg/kg |
732 |
24.8 |
24.9 |
26.8 |
27.6 |
29.8 |
30.2 |
31.3 |
32.8 |
33.7 |
34.3 |
36.8 |
36.1 |
40 |
|
41.8 |
45.9 |
45 |
50.1 |
50.2 |
52 |
53.5 |
53.8 |
|
54.4 |
|
55.7 |
54 |
|
54.1 |
|
|
55.2 |
|
|
56.3 |
|
|
|
57.1 |
|
57.3 |
|
|
|
58.9 |
|
|
|
59.7 |
|
|
|
59.5 |
|
|
62.9 |
|
|
|
64.2 |
|
|
|
|
65.2 |
Terminal Sacrifice |
170 |
170 |
250mg/kg |
596 |
23.8 |
23.9 |
25.4 |
25.5 |
27.2 |
27.7 |
28.9 |
30.3 |
30.5 |
30.9 |
32.9 |
33.9 |
37.9 |
|
39.9 |
44 |
45.6 |
46.2 |
48.8 |
49.7 |
54.3 |
53.1 |
|
53.7 |
|
55.4 |
55.4 |
|
56.1 |
|
|
56.3 |
|
|
57.5 |
|
|
|
58.2 |
|
59.1 |
|
|
|
60.1 |
46 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
171 |
171 |
250mg/kg |
731 |
22.7 |
24.2 |
24.9 |
26.2 |
28.1 |
28.3 |
30 |
31.7 |
32.9 |
33.1 |
36.2 |
35.1 |
41 |
|
43.4 |
47.4 |
47.6 |
50.3 |
51.4 |
51.8 |
53 |
51.7 |
|
53.4 |
|
53.5 |
55 |
|
55.3 |
|
|
55.8 |
|
|
56.5 |
|
|
|
57 |
|
56 |
|
|
|
57.2 |
|
|
|
58.7 |
|
|
|
57.5 |
|
|
52.9 |
|
|
|
47.5 |
|
|
|
|
40.8 |
Terminal Sacrifice |
172 |
172 |
250mg/kg |
732 |
26.1 |
26.9 |
28.2 |
29.8 |
31.8 |
33.2 |
34.7 |
36.7 |
38.2 |
37.7 |
39.8 |
38.9 |
45.2 |
|
48.3 |
50 |
51.9 |
54.2 |
53.7 |
52.7 |
55.3 |
54.9 |
|
56.2 |
|
56.3 |
57 |
|
57.4 |
|
|
59.2 |
|
|
58.5 |
|
|
|
58.5 |
|
58.7 |
|
|
|
59.7 |
|
|
|
61.2 |
|
|
|
62.6 |
|
|
62.4 |
|
|
|
64.6 |
|
|
|
|
60 |
Terminal Sacrifice |
173 |
173 |
250mg/kg |
732 |
25.6 |
26.2 |
28.1 |
28.8 |
31.4 |
29.7 |
31.5 |
33 |
33.7 |
34.1 |
36.2 |
35.8 |
43 |
|
46.8 |
50.9 |
50.4 |
53.3 |
52.2 |
53 |
53.6 |
55 |
|
56.3 |
|
56 |
56.2 |
|
56.3 |
|
|
58 |
|
|
56.4 |
|
|
|
58.7 |
|
57.9 |
|
|
|
56.4 |
|
|
|
52.4 |
|
|
|
50 |
|
|
46.3 |
|
|
|
42.9 |
|
|
|
|
37.8 |
Terminal Sacrifice |
174 |
174 |
250mg/kg |
731 |
23.2 |
23.6 |
26.1 |
26.7 |
27.8 |
28.2 |
30.8 |
33.2 |
31.5 |
34.9 |
36.4 |
37.1 |
45.8 |
|
46.3 |
50.4 |
48.9 |
53.9 |
52.7 |
55.5 |
57.4 |
57.9 |
|
60.4 |
|
60.2 |
59.4 |
|
60 |
|
|
61.6 |
|
|
63.2 |
|
|
|
64.8 |
|
66.8 |
|
|
|
66.1 |
|
|
|
67.1 |
|
|
|
68.8 |
|
|
69.7 |
|
|
|
69 |
|
|
|
|
64.3 |
Terminal Sacrifice |
175 |
175 |
250mg/kg |
511 |
22.4 |
22.8 |
24 |
24.5 |
26.4 |
27 |
28.3 |
29.1 |
31.2 |
31.1 |
32.7 |
31.9 |
37.5 |
|
38 |
41.2 |
42.9 |
44.2 |
44.2 |
45.9 |
49 |
49.9 |
|
53.7 |
|
54.1 |
53.5 |
|
53.4 |
|
|
52.6 |
|
|
53.5 |
52.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Accidentally Killed |
176 |
176 |
250mg/kg |
616 |
25.2 |
25.7 |
27.2 |
27.8 |
28.8 |
30 |
31.1 |
33 |
32.4 |
33.2 |
34.7 |
35 |
40 |
|
44.6 |
45.5 |
49.1 |
53.2 |
51.5 |
53.5 |
55.7 |
55.6 |
|
57 |
|
56.5 |
56.6 |
|
57.1 |
|
|
59 |
|
|
58.8 |
|
|
|
58.9 |
|
58.8 |
|
|
|
60.3 |
|
|
|
35.8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
177 |
177 |
250mg/kg |
732 |
24.3 |
25 |
26.5 |
26.7 |
28.7 |
29.1 |
29.5 |
30.8 |
30.6 |
31.5 |
33 |
32.9 |
37.2 |
|
39.6 |
40.9 |
40.5 |
43.2 |
45.1 |
45.1 |
47 |
49.6 |
|
50.4 |
|
51.2 |
55.1 |
|
54.7 |
|
|
54.5 |
|
|
55.7 |
|
|
|
56.1 |
|
55.8 |
|
|
|
56.2 |
|
|
|
56.7 |
|
|
|
55.7 |
|
|
57.3 |
|
|
|
56.9 |
|
|
|
|
58 |
Terminal Sacrifice |
178 |
178 |
250mg/kg |
732 |
22.9 |
23.5 |
24.5 |
24.8 |
26.3 |
26.9 |
28.7 |
30 |
29.7 |
31.4 |
33.3 |
33.5 |
37.3 |
|
39.4 |
41.3 |
44.9 |
52.2 |
51.9 |
51.5 |
50.6 |
51.8 |
|
53.9 |
|
53.4 |
55.6 |
|
55.7 |
|
|
57.1 |
|
|
58 |
|
|
|
58.7 |
|
60 |
|
|
|
61.3 |
|
|
|
60.9 |
|
|
|
60.2 |
|
|
53.9 |
|
|
|
48 |
|
|
|
|
42.3 |
Terminal Sacrifice |
179 |
179 |
250mg/kg |
730 |
24.8 |
25.3 |
27.3 |
28.1 |
29.3 |
30.3 |
31.9 |
32.8 |
33.9 |
34.5 |
35.5 |
36.4 |
39.3 |
|
40.6 |
44.4 |
46.4 |
48.3 |
51.9 |
52.8 |
52.6 |
53.6 |
|
54.9 |
|
54.5 |
55.8 |
|
56.2 |
|
|
56.1 |
|
|
57 |
|
|
|
57.3 |
|
55.4 |
|
|
|
50.1 |
|
|
|
53.9 |
|
|
|
53.3 |
|
|
51.1 |
|
|
|
43.3 |
|
|
|
|
31.1 |
Terminal Sacrifice |
180 |
180 |
250mg/kg |
385 |
26.2 |
26.5 |
28.4 |
29 |
31.1 |
31.2 |
32.4 |
34.6 |
35.2 |
35 |
37.5 |
37.6 |
40.8 |
|
45.3 |
47.9 |
49.2 |
50.7 |
54.5 |
52.5 |
47.8 |
43 |
|
41.6 |
40.9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
181 |
181 |
250mg/kg |
732 |
25.7 |
26.5 |
29 |
30 |
31.7 |
31.5 |
33.9 |
35.3 |
36.5 |
36.8 |
38.9 |
40.2 |
45.6 |
|
49.3 |
51.9 |
52.2 |
52.5 |
52.6 |
53.5 |
55.1 |
55.6 |
|
57.2 |
|
57.6 |
58.2 |
|
58.9 |
|
|
59.4 |
|
|
58.9 |
|
|
|
60.2 |
|
60.5 |
|
|
|
60.8 |
|
|
|
60.9 |
|
|
|
58.1 |
|
|
54.5 |
|
|
|
49.8 |
|
|
|
|
44.8 |
Terminal Sacrifice |
182 |
182 |
250mg/kg |
730 |
23.3 |
24.9 |
26.2 |
26.8 |
27.4 |
27.9 |
28.8 |
29.6 |
31.8 |
31.9 |
33.8 |
32.6 |
37.1 |
|
37.3 |
42.4 |
41.7 |
45 |
45.8 |
50.6 |
53.1 |
49.1 |
|
54.3 |
|
55.1 |
54.8 |
|
55.2 |
|
|
57.2 |
|
|
58 |
|
|
|
58.5 |
|
58.9 |
|
|
|
59.5 |
|
|
|
60.4 |
|
|
|
57.4 |
|
|
61 |
|
|
|
62.9 |
|
|
|
|
63.9 |
Terminal Sacrifice |
183 |
183 |
250mg/kg |
586 |
25.7 |
26.8 |
28.9 |
29.8 |
32.1 |
32.6 |
33.7 |
34 |
36.1 |
37.5 |
40.6 |
39.9 |
45.6 |
|
49.6 |
51.3 |
51.8 |
53.6 |
53 |
53.8 |
55.2 |
55.1 |
|
54.5 |
|
56.2 |
55.6 |
|
57.5 |
|
|
56.2 |
|
|
56.3 |
|
|
|
55.4 |
|
53.3 |
|
|
|
50.7 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
184 |
184 |
250mg/kg |
631 |
23.1 |
24.3 |
25.6 |
26 |
27.2 |
28.9 |
30.7 |
32.1 |
32.9 |
34.1 |
33.8 |
34.5 |
39.7 |
|
44.6 |
47.4 |
45.2 |
50.6 |
52 |
53 |
54 |
52.9 |
|
53.4 |
|
54.2 |
54.7 |
|
54.8 |
|
|
54.1 |
|
|
53.6 |
|
|
|
53.1 |
|
52.6 |
|
|
|
37.3 |
|
|
|
39.6 |
|
40.5 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
185 |
185 |
250mg/kg |
637 |
24.5 |
25.6 |
26.8 |
27.6 |
28.8 |
30.6 |
31.9 |
33.9 |
34 |
34.3 |
35.5 |
36 |
40.8 |
|
44.7 |
46.5 |
49.2 |
52.7 |
54.3 |
55.3 |
55.6 |
56.2 |
|
57.4 |
|
57.9 |
58.7 |
|
59 |
|
|
59.9 |
|
|
58.9 |
|
|
|
60.2 |
|
59.7 |
|
|
|
60.1 |
|
|
|
58.8 |
|
|
44.7 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
186 |
186 |
250mg/kg |
732 |
23.7 |
24 |
26 |
26.4 |
28.1 |
29.1 |
30.1 |
32.1 |
31.5 |
33.4 |
35 |
34.8 |
39.2 |
|
40 |
41.6 |
43.7 |
47.5 |
49.8 |
51 |
51.9 |
52.4 |
|
53.4 |
|
54.7 |
54.5 |
|
56 |
|
|
55.4 |
|
|
56.6 |
|
|
|
56.9 |
|
56.7 |
|
|
|
54.1 |
|
|
|
54.3 |
|
|
|
57.7 |
|
|
57.9 |
|
|
|
56.6 |
|
|
|
|
54.6 |
Terminal Sacrifice |
187 |
187 |
250mg/kg |
686 |
23.8 |
25.1 |
26.2 |
27 |
28.6 |
29.2 |
32.2 |
33.7 |
34.7 |
34.8 |
38 |
38.2 |
40.4 |
|
45.1 |
47.6 |
51.1 |
53.1 |
52.3 |
52.2 |
52.5 |
54.1 |
|
55.5 |
|
56.7 |
58.3 |
|
59.7 |
|
|
61.1 |
|
|
62.2 |
|
|
|
62.1 |
|
62 |
|
|
|
63.5 |
|
|
|
65.6 |
|
|
|
64.3 |
|
|
52.5 |
|
43.4 |
|
|
|
|
|
|
|
Natural Death |
188 |
188 |
250mg/kg |
732 |
24 |
24.4 |
25.1 |
26.3 |
26.7 |
27 |
28.2 |
29.8 |
29.8 |
29 |
32.4 |
32.9 |
35.6 |
|
38.7 |
42.2 |
42.6 |
44 |
46.6 |
48.2 |
49.9 |
48.7 |
|
48.7 |
|
50.3 |
50.2 |
|
51 |
|
|
50.9 |
|
|
47.3 |
|
|
|
51 |
|
50.7 |
|
|
|
52.2 |
|
|
|
51.9 |
|
|
|
51.5 |
|
|
51 |
|
|
|
52.6 |
|
|
|
|
52.1 |
Terminal Sacrifice |
189 |
189 |
250mg/kg |
495 |
24.7 |
26.2 |
28.3 |
28.1 |
29.9 |
30.2 |
32.9 |
35.2 |
35.6 |
36.9 |
39.7 |
39.5 |
46 |
|
48.9 |
51.4 |
50.7 |
52.9 |
53.3 |
54.5 |
57.9 |
58.4 |
|
57.8 |
|
57.2 |
59.1 |
|
57.2 |
|
|
56.8 |
|
52.9 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Natural Death |
190 |
190 |
250mg/kg |
732 |
24.4 |
25.3 |
27.3 |
27.7 |
29.8 |
31 |
31.6 |
33 |
32 |
33.1 |
35.1 |
35.4 |
37.6 |
|
42.3 |
44 |
39.3 |
48.4 |
51.1 |
53.2 |
53.1 |
50.8 |
|
49.9 |
|
50.2 |
50 |
|
48.4 |
|
|
46.5 |
|
|
45.7 |
|
|
|
42.3 |
|
39.5 |
|
|
|
37 |
|
|
|
36.4 |
|
|
|
35 |
|
|
33.8 |
|
|
|
33.3 |
|
|
|
|
26.4 |
Terminal Sacrifice |
191 |
191 |
250mg/kg |
437 |
23.6 |
24.8 |
26.5 |
26.9 |
28.5 |
29.1 |
30.4 |
31.5 |
32.9 |
33.9 |
34.6 |
33.9 |
38.4 |
|
40.4 |
41.9 |
43.6 |
46.9 |
47.2 |
49.5 |
50.1 |
49.2 |
|
50.6 |
|
50.6 |
52.5 |
53.2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
192 |
192 |
250mg/kg |
715 |
23.9 |
24.1 |
25.7 |
26.9 |
27.8 |
28.2 |
29.6 |
31.2 |
32.2 |
32.9 |
34 |
33.7 |
36.4 |
|
37.3 |
40.8 |
43.6 |
45.4 |
48.1 |
47.8 |
49.8 |
50.6 |
|
51.3 |
|
52.7 |
52.4 |
|
51 |
|
|
52.9 |
|
|
53.4 |
|
|
|
54.8 |
|
53.9 |
|
|
|
55.3 |
|
|
|
55 |
|
|
|
53.8 |
|
|
52.4 |
|
|
|
46.7 |
|
41.9 |
|
|
|
Moribund Sacrifice |
193 |
193 |
250mg/kg |
730 |
22.6 |
23.7 |
25.6 |
26.5 |
27.2 |
28.2 |
30.4 |
30.6 |
31.3 |
32.3 |
34.5 |
34.2 |
37.8 |
|
41.1 |
43.4 |
43.6 |
45.8 |
46.7 |
50.5 |
51.9 |
50.9 |
|
54.1 |
|
54.9 |
54 |
|
54.6 |
|
|
54.9 |
|
|
55.4 |
|
|
|
55.2 |
|
53.4 |
|
|
|
55.3 |
|
|
|
54.9 |
|
|
|
55.2 |
|
|
56.7 |
|
|
|
55.2 |
|
|
|
|
52.3 |
Terminal Sacrifice |
194 |
194 |
250mg/kg |
690 |
24.7 |
26.3 |
28.9 |
29.6 |
32.2 |
33 |
34.8 |
35.9 |
36.3 |
37.7 |
40.4 |
41.5 |
47.1 |
|
50.3 |
52.2 |
51.5 |
53.7 |
52 |
54.3 |
55.8 |
55.7 |
|
56.6 |
|
58.6 |
58.2 |
|
58.9 |
|
|
58.7 |
|
|
59 |
|
|
|
58.1 |
|
57.2 |
|
|
|
57.4 |
|
|
|
52.9 |
|
|
|
46.6 |
|
|
39.6 |
|
|
38 |
|
|
|
|
|
|
Natural Death |
195 |
195 |
250mg/kg |
730 |
24.9 |
25.3 |
26.7 |
28.2 |
30.2 |
31.3 |
34 |
34.6 |
37.2 |
38.5 |
40.7 |
40.1 |
48.2 |
|
50.6 |
51.5 |
52.5 |
52.7 |
53.1 |
53.8 |
56.1 |
55.5 |
|
56.9 |
|
57.3 |
58 |
|
57.7 |
|
|
59.4 |
|
|
60.6 |
|
|
|
61.3 |
|
61.7 |
|
|
|
62.3 |
|
|
|
61.9 |
|
|
|
57.9 |
|
|
54.5 |
|
|
|
49.4 |
|
|
|
|
45.9 |
Terminal Sacrifice |
196 |
196 |
250mg/kg |
617 |
24.3 |
25.9 |
27.7 |
28.7 |
31 |
32.5 |
34 |
36.5 |
37.6 |
39.4 |
41.3 |
42 |
45.6 |
|
49.7 |
50.7 |
48.3 |
52.9 |
51.9 |
51.9 |
55.6 |
54.9 |
|
54.8 |
|
56.1 |
55.3 |
|
55.3 |
|
|
55.8 |
|
|
56.8 |
|
|
|
57.4 |
|
58.4 |
|
|
|
58.2 |
|
|
|
53.4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Moribund Sacrifice |
197 |
197 |
250mg/kg |
731 |
25 |
25.6 |
27.7 |
29 |
30.8 |
32.5 |
33.6 |
34.9 |
35.9 |
36.4 |
39.7 |
40 |
44.9 |
|
48.3 |
49.5 |
48.7 |
53.5 |
54 |
53.5 |
53.9 |
55.6 |
|
55 |
|
56.1 |
57.8 |
|
57.2 |
|
|
57.1 |
|
|
58.9 |
|
|
|
56.7 |
|
56.5 |
|
|
|
57.4 |
|
|
|
56 |
|
|
|
53.2 |
|
|
49.7 |
|
|
|
47 |
|
|
|
|
43.7 |
Terminal Sacrifice |
198 |
198 |
250mg/kg |
732 |
23.9 |
24.3 |
25.8 |
27.1 |
29.3 |
30.2 |
31.9 |
32.9 |
33.4 |
34.9 |
37.5 |
37.1 |
41.3 |
|
43.3 |
46.3 |
48.1 |
51.4 |
51.3 |
54.4 |
54.4 |
55.1 |
|
56.2 |
|
55.9 |
55.9 |
|
57.2 |
|
|
57.8 |
|
|
58.8 |
|
|
|
58.9 |
|
59.7 |
|
|
|
60.9 |
|
|
|
64 |
|
|
|
63.7 |
|
|
59.5 |
|
|
|
55.9 |
|
|
|
|
50.9 |
Terminal Sacrifice |
199 |
199 |
250mg/kg |
671 |
23.8 |
25.1 |
26.8 |
28 |
28.9 |
30.5 |
32.1 |
32.3 |
33.8 |
35 |
38.4 |
38.8 |
43.7 |
|
47.4 |
47.3 |
49.2 |
52.7 |
51.3 |
51.8 |
52.1 |
53.4 |
|
54 |
|
55.3 |
54.9 |
|
56.7 |
|
|
58.1 |
|
|
57.8 |
|
|
|
58 |
|
57.9 |
|
|
|
57.1 |
|
|
|
56.4 |
|
|
|
54.2 |
|
|
48.3 |
|
|
|
|
|
|
|
|
|
Natural Death |
200 |
200 |
250mg/kg |
716 |
25.7 |
26.2 |
28.2 |
29.6 |
30.4 |
32.2 |
33.9 |
36.7 |
36.7 |
36.8 |
39.7 |
40.7 |
45.4 |
|
46.8 |
52.1 |
51.8 |
52.6 |
52.4 |
52.3 |
53.6 |
54.6 |
|
55.1 |
|
55.3 |
56.8 |
|
57.4 |
|
|
58.6 |
|
|
59.8 |
|
|
|
61 |
|
61 |
|
|
|
61.3 |
|
|
|
60.9 |
|
|
|
58.1 |
|
|
51.1 |
|
|
|
37.6 |
|
|
37 |
|
|
Natural Death |
* All body weights in grams