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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: p-Chloro-a,a,a-trifluorotoluene
CASRN: ="98-56-6"
Study Number: C10472B
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 1047203
Sex: Male
Strain and Species: HSD Rats

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Esophagus Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Intestine Large Colon Vehicle Control 50 10 50 537 1 Leiomyoma Moribund Sacrifice
Alimentary System Intestine Small Duodenum 100 ppm 50 28 238 730 1 Adenocarcinoma Terminal Sacrifice
Alimentary System Intestine Small Duodenum 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Intestine Small Jejunum 100 ppm 50 21 203 525 1 Adenocarcinoma Natural Death
Alimentary System Intestine Small Jejunum 100 ppm 50 27 233 729 1 Adenocarcinoma Terminal Sacrifice
Alimentary System Intestine Small Jejunum 300 ppm 50 45 423 611 1 Adenocarcinoma Moribund Sacrifice
Alimentary System Intestine Small Jejunum Vehicle Control 50 2 9 722 1 Leiomyosarcoma Moribund Sacrifice
Alimentary System Intestine Small Jejunum 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Liver 100 ppm 50 28 236 631 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 100 ppm 50 22 207 730 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 100 ppm 50 26 230 730 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 1000 ppm 50 66 626 612 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Alimentary System Liver 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Liver 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Liver 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Alimentary System Liver 1000 ppm 50 62 608 528 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Alimentary System Mesentery Vehicle Control 2 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Pancreas Acinus 100 ppm 50 30 248 589 1 Adenoma Moribund Sacrifice
Alimentary System Pancreas Acinus 300 ppm 50 46 426 729 1 Adenoma Terminal Sacrifice
Alimentary System Pancreas Acinus 1000 ppm 50 70 646 648 1 Adenoma Natural Death
Alimentary System Pancreas Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Pancreas Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Pancreas 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Pancreas 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Pancreas 300 ppm 50 43 413 730 1 Lymphoma Malignant Terminal Sacrifice
Alimentary System Salivary Glands 100 ppm 50 27 231 306 1 Carcinoma Moribund Sacrifice
Alimentary System Stomach Forestomach Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Stomach Forestomach 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Stomach Forestomach 100 ppm 50 30 247 680 1 Squamous Cell Papilloma Moribund Sacrifice
Alimentary System Stomach Forestomach 100 ppm 50 30 248 589 1 Squamous Cell Papilloma Moribund Sacrifice
Alimentary System Stomach Glandular Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Alimentary System Tooth Vehicle Control 1 2 9 722 1 Odontoma Moribund Sacrifice
Cardiovascular System Heart Endocardium 300 ppm 50 41 401 463 1 Schwannoma Malignant Natural Death
Cardiovascular System Heart Endocardium 1000 ppm 50 62 608 528 1 Schwannoma Malignant Moribund Sacrifice
Cardiovascular System Heart Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Cardiovascular System Heart Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Cardiovascular System Heart 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Cardiovascular System Heart 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Cardiovascular System Heart 1000 ppm 50 68 638 621 1 Sarcoma Moribund Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 50 6 29 661 1 Adenoma Moribund Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 50 10 46 516 1 Adenoma Natural Death
Endocrine System Adrenal Cortex Vehicle Control 50 3 11 730 1 Adenoma Terminal Sacrifice
Endocrine System Adrenal Cortex 100 ppm 50 27 234 729 1 Adenoma Terminal Sacrifice
Endocrine System Adrenal Cortex 1000 ppm 50 63 615 645 1 Adenoma Natural Death
Endocrine System Adrenal Cortex 300 ppm 50 44 419 697 1 Carcinoma Moribund Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Endocrine System Adrenal Cortex 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Endocrine System Adrenal Cortex 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Endocrine System Adrenal Medulla Bilateral Vehicle Control 50 2 6 674 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla Bilateral Vehicle Control 50 10 49 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Bilateral Vehicle Control 50 3 11 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Bilateral Vehicle Control 50 5 21 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Bilateral 100 ppm 50 22 208 618 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla Bilateral 100 ppm 50 26 227 570 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla Bilateral 100 ppm 50 25 221 717 1 Pheochromocytoma Benign Natural Death
Endocrine System Adrenal Medulla Bilateral 100 ppm 50 28 240 643 1 Pheochromocytoma Benign Natural Death
Endocrine System Adrenal Medulla Bilateral 100 ppm 50 27 233 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Bilateral 300 ppm 50 42 408 530 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla Bilateral 300 ppm 50 48 437 571 1 Pheochromocytoma Benign Natural Death
Endocrine System Adrenal Medulla Bilateral 300 ppm 50 47 434 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Bilateral 300 ppm 50 47 435 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Bilateral 1000 ppm 50 62 608 528 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla Bilateral 1000 ppm 50 64 617 703 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Endocrine System Adrenal Medulla Vehicle Control 50 2 9 722 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 5 24 374 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 9 44 723 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 1 2 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 3 12 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 5 22 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 6 26 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 9 41 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 100 ppm 50 29 243 485 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 100 ppm 50 30 246 676 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 100 ppm 50 30 249 650 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 100 ppm 50 21 201 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 100 ppm 50 21 202 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 100 ppm 50 22 206 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 100 ppm 50 26 230 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 100 ppm 50 29 242 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 41 404 669 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 41 405 678 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 44 419 697 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 45 424 597 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 46 427 717 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 46 430 534 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 47 431 618 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 48 439 528 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 43 411 717 1 Pheochromocytoma Benign Natural Death
Endocrine System Adrenal Medulla 300 ppm 50 48 436 500 1 Pheochromocytoma Benign Natural Death
Endocrine System Adrenal Medulla 300 ppm 50 41 403 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 50 450 729 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 63 613 718 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 64 619 703 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 64 620 686 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 65 625 591 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 68 636 575 1 Pheochromocytoma Benign Moribund Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 65 623 476 1 Pheochromocytoma Benign Natural Death
Endocrine System Adrenal Medulla 1000 ppm 50 66 628 617 1 Pheochromocytoma Benign Natural Death
Endocrine System Adrenal Medulla 1000 ppm 50 70 646 648 1 Pheochromocytoma Benign Natural Death
Endocrine System Adrenal Medulla 1000 ppm 50 64 616 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 67 635 730 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 7 35 533 1 Pheochromocytoma Malignant Moribund Sacrifice
Endocrine System Adrenal Medulla Vehicle Control 50 9 45 729 1 Pheochromocytoma Malignant Terminal Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 45 425 717 1 Pheochromocytoma Malignant Moribund Sacrifice
Endocrine System Adrenal Medulla 300 ppm 50 49 442 607 1 Pheochromocytoma Malignant Moribund Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 70 647 571 1 Pheochromocytoma Malignant Moribund Sacrifice
Endocrine System Adrenal Medulla 1000 ppm 50 62 606 573 1 Pheochromocytoma Malignant Natural Death
Endocrine System Islets Pancreatic Vehicle Control 50 6 27 663 1 Adenoma Moribund Sacrifice
Endocrine System Islets Pancreatic Vehicle Control 50 7 35 533 1 Adenoma Moribund Sacrifice
Endocrine System Islets Pancreatic Vehicle Control 50 4 16 648 1 Adenoma Natural Death
Endocrine System Islets Pancreatic Vehicle Control 50 8 36 726 1 Adenoma Natural Death
Endocrine System Islets Pancreatic Vehicle Control 50 1 3 729 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic Vehicle Control 50 5 22 729 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic Vehicle Control 50 5 23 729 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic Vehicle Control 50 7 34 729 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic 100 ppm 50 25 225 655 1 Adenoma Moribund Sacrifice
Endocrine System Islets Pancreatic 100 ppm 50 22 206 730 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic 100 ppm 50 22 207 730 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic 100 ppm 50 27 233 729 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic 100 ppm 50 28 238 730 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic 300 ppm 50 44 420 607 1 Adenoma Natural Death
Endocrine System Islets Pancreatic 300 ppm 50 41 403 729 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic 100 ppm 50 30 250 674 1 Carcinoma Moribund Sacrifice
Endocrine System Islets Pancreatic 100 ppm 50 21 204 729 1 Carcinoma Terminal Sacrifice
Endocrine System Islets Pancreatic 100 ppm 50 24 218 729 1 Carcinoma Terminal Sacrifice
Endocrine System Islets Pancreatic 100 ppm 50 26 226 729 1 Carcinoma Terminal Sacrifice
Endocrine System Islets Pancreatic 1000 ppm 50 64 620 686 1 Carcinoma Moribund Sacrifice
Endocrine System Parathyroid Gland 1000 ppm 50 69 645 575 1 Adenoma Moribund Sacrifice
Endocrine System Parathyroid Gland 1000 ppm 50 69 644 729 1 Adenoma Terminal Sacrifice
Endocrine System Parathyroid Gland 1000 ppm 50 70 649 709 1 Carcinoma Metastatic Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 9 44 723 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 1 1 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 1 5 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 10 49 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 3 11 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 3 12 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 5 21 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 5 22 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 5 25 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 6 26 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 50 9 41 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 100 ppm 50 25 223 715 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 100 ppm 50 28 239 607 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 100 ppm 50 23 214 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 100 ppm 50 24 218 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 100 ppm 50 26 226 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 100 ppm 50 27 232 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 300 ppm 50 43 411 717 1 Adenoma Natural Death
Endocrine System Pituitary Gland Pars Distalis 300 ppm 50 50 449 726 1 Adenoma Natural Death
Endocrine System Pituitary Gland Pars Distalis 300 ppm 50 41 402 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 300 ppm 50 41 403 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 300 ppm 50 43 413 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 300 ppm 50 46 429 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 300 ppm 50 47 432 730 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 1000 ppm 50 62 609 727 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 1000 ppm 50 67 632 430 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 1000 ppm 50 69 641 654 1 Adenoma Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis 1000 ppm 50 66 627 530 1 Adenoma Natural Death
Endocrine System Pituitary Gland Pars Distalis 1000 ppm 50 69 643 492 1 Adenoma Natural Death
Endocrine System Pituitary Gland Pars Distalis 1000 ppm 50 69 644 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 300 ppm 50 47 433 730 1 Histiocytic Sarcoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Intermed 1000 ppm 50 67 633 729 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 100 ppm 50 25 224 565 1 Carcinoma Metastatic Moribund Sacrifice
Endocrine System Pituitary Gland Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Endocrine System Thyroid Gland Bilateral, C Cell 100 ppm 50 27 233 729 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Bilateral, C Cell 300 ppm 50 47 435 730 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Bilateral, C Cell 1000 ppm 50 64 617 703 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland C Cell Vehicle Control 50 3 11 730 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell Vehicle Control 50 9 41 730 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 100 ppm 50 30 247 680 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland C Cell 100 ppm 50 24 217 729 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 100 ppm 50 25 222 730 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 100 ppm 50 27 232 730 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 300 ppm 50 41 404 669 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland C Cell 300 ppm 50 42 409 697 1 Adenoma Natural Death
Endocrine System Thyroid Gland C Cell 1000 ppm 50 63 613 718 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland C Cell 1000 ppm 50 64 619 703 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland C Cell 1000 ppm 50 65 621 688 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland C Cell 1000 ppm 50 63 611 704 1 Adenoma Natural Death
Endocrine System Thyroid Gland C Cell 1000 ppm 50 63 615 645 1 Adenoma Natural Death
Endocrine System Thyroid Gland C Cell 1000 ppm 50 65 622 589 1 Adenoma Natural Death
Endocrine System Thyroid Gland C Cell 1000 ppm 50 66 628 617 1 Adenoma Natural Death
Endocrine System Thyroid Gland C Cell 1000 ppm 50 70 650 568 1 Adenoma Natural Death
Endocrine System Thyroid Gland C Cell 1000 ppm 50 64 616 730 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 1000 ppm 50 67 633 729 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 1000 ppm 50 68 639 729 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell Vehicle Control 50 9 45 729 1 Carcinoma Terminal Sacrifice
Endocrine System Thyroid Gland C Cell 300 ppm 50 43 414 691 1 Carcinoma Natural Death
Endocrine System Thyroid Gland C Cell 1000 ppm 50 70 649 709 1 Carcinoma Moribund Sacrifice
Endocrine System Thyroid Gland Follicular Cel 300 ppm 50 48 438 703 1 Adenoma Moribund Sacrifice
Endocrine System Thyroid Gland Follicular Cel 1000 ppm 50 63 612 616 1 Adenoma Natural Death
Endocrine System Thyroid Gland Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Genital System Epididymis Vehicle Control 50 2 8 677 1 Mesothelioma Malignant Natural Death
Genital System Epididymis 300 ppm 50 44 418 674 1 Mesothelioma Malignant Moribund Sacrifice
Genital System Epididymis Vehicle Control 50 5 24 374 1 Sarcoma Moribund Sacrifice
Genital System Preputial Gland 300 ppm 50 44 418 674 1 Carcinoma Moribund Sacrifice
Genital System Prostate Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Genital System Prostate 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Genital System Seminal Vesicle 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Genital System Testes Interstit Cell 100 ppm 50 22 208 618 1 Adenoma Moribund Sacrifice
Genital System Testes Interstit Cell 100 ppm 50 23 214 730 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 300 ppm 50 50 448 528 1 Adenoma Moribund Sacrifice
Genital System Testes Interstit Cell 300 ppm 50 44 417 729 1 Adenoma Terminal Sacrifice
Genital System Testes Vehicle Control 50 2 8 677 1 Mesothelioma Malignant Natural Death
Hematopoietic System Bone Marrow Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Hematopoietic System Bone Marrow Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Bone Marrow 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Axillary Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Hematopoietic System Lymph Node Bronchial Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Hematopoietic System Lymph Node Bronchial Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Iliac Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Iliac 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Hematopoietic System Lymph Node Mandibular 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Hematopoietic System Lymph Node Mediastinal Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Hematopoietic System Lymph Node Mediastinal Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mediastinal Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mediastinal Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Hematopoietic System Lymph Node Mediastinal 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mediastinal 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mediastinal 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Hematopoietic System Lymph Node Mesenteric Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Hematopoietic System Lymph Node Mesenteric 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Hematopoietic System Lymph Node Pancreatic Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Hematopoietic System Lymph Node Pancreatic 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Renal Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Hematopoietic System Lymph Node Renal Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Lymph Node Renal 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Spleen Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Hematopoietic System Spleen Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Spleen Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Spleen Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Hematopoietic System Spleen 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Spleen 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Spleen 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Hematopoietic System Thymus Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Thymus Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Hematopoietic System Thymus 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Hematopoietic System Thymus 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Integumentary System Mammary Gland 100 ppm 50 24 219 640 1 Adenoma Natural Death
Integumentary System Mammary Gland Vehicle Control 50 1 1 729 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland Vehicle Control 50 9 43 730 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 100 ppm 50 27 234 729 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 300 ppm 50 46 426 729 1 Fibroadenoma Terminal Sacrifice
Integumentary System Mammary Gland 300 ppm 50 47 435 730 1 Fibroadenoma Terminal Sacrifice
Integumentary System Skin Sebaceous Gl Vehicle Control 50 4 18 568 1 Adenoma Moribund Sacrifice
Integumentary System Skin Sebaceous Gl 100 ppm 50 30 249 650 1 Adenoma Moribund Sacrifice
Integumentary System Skin Sebaceous Gl 100 ppm 50 28 238 730 1 Adenoma Terminal Sacrifice
Integumentary System Skin Sebaceous Gl 300 ppm 50 42 410 730 1 Adenoma Terminal Sacrifice
Integumentary System Skin Sebaceous Gl 300 ppm 50 43 412 729 1 Adenoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 100 ppm 50 30 247 680 1 Fibroma Moribund Sacrifice
Integumentary System Skin Subcut Tiss 100 ppm 50 22 207 730 1 Fibroma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 100 ppm 50 27 233 729 1 Fibroma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 100 ppm 50 27 235 729 1 Fibroma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 300 ppm 50 45 424 597 1 Fibroma Moribund Sacrifice
Integumentary System Skin Subcut Tiss 300 ppm 50 50 446 590 1 Fibroma Moribund Sacrifice
Integumentary System Skin Subcut Tiss Vehicle Control 50 10 48 584 1 Fibrous Histiocytoma Moribund Sacrifice
Integumentary System Skin Subcut Tiss 100 ppm 50 23 215 318 1 Fibrous Histiocytoma Moribund Sacrifice
Integumentary System Skin Subcut Tiss Vehicle Control 50 10 50 537 1 Hemangioma Moribund Sacrifice
Integumentary System Skin Subcut Tiss 300 ppm 50 45 423 611 1 Hemangioma Moribund Sacrifice
Integumentary System Skin Subcut Tiss Vehicle Control 50 3 12 730 1 Lipoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 100 ppm 50 21 205 730 1 Lipoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 300 ppm 50 47 432 730 1 Lipoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 300 ppm 50 42 410 730 1 Schwannoma Malignant Terminal Sacrifice
Integumentary System Skin Subcut Tiss 300 ppm 50 43 413 730 1 Schwannoma Malignant Terminal Sacrifice
Integumentary System Skin 300 ppm 50 46 426 729 1 Basal Cell Adenoma Terminal Sacrifice
Integumentary System Skin 300 ppm 50 47 435 730 1 Basal Cell Adenoma Terminal Sacrifice
Integumentary System Skin Vehicle Control 50 7 33 618 Multiple Keratoacanthoma Moribund Sacrifice
Integumentary System Skin Vehicle Control 50 10 49 729 1 Keratoacanthoma Terminal Sacrifice
Integumentary System Skin Vehicle Control 50 2 10 730 1 Keratoacanthoma Terminal Sacrifice
Integumentary System Skin 100 ppm 50 24 217 729 1 Keratoacanthoma Terminal Sacrifice
Integumentary System Skin 100 ppm 50 28 238 730 1 Keratoacanthoma Terminal Sacrifice
Integumentary System Skin 300 ppm 50 44 417 729 Multiple Keratoacanthoma Terminal Sacrifice
Integumentary System Skin 300 ppm 50 47 434 729 1 Keratoacanthoma Terminal Sacrifice
Integumentary System Skin 1000 ppm 50 68 640 549 1 Keratoacanthoma Moribund Sacrifice
Integumentary System Skin 1000 ppm 50 64 618 467 1 Keratoacanthoma Natural Death
Integumentary System Skin 1000 ppm 50 67 635 730 1 Keratoacanthoma Terminal Sacrifice
Integumentary System Skin Vehicle Control 50 2 9 722 1 Squamous Cell Papilloma Moribund Sacrifice
Integumentary System Skin 100 ppm 50 22 209 729 1 Squamous Cell Papilloma Terminal Sacrifice
Integumentary System Skin 100 ppm 50 28 238 730 1 Squamous Cell Papilloma Terminal Sacrifice
Integumentary System Skin 1000 ppm 50 67 635 730 1 Squamous Cell Papilloma Terminal Sacrifice
Musculoskeletal System Bone 300 ppm 50 49 441 696 1 Osteosarcoma Natural Death
Musculoskeletal System Skeletal Muscle 100 ppm 6 26 230 730 1 Hemangiosarcoma Terminal Sacrifice
Musculoskeletal System Skeletal Muscle 100 ppm 6 29 241 310 1 Schwannoma Malignant Moribund Sacrifice
Nervous System Brain Vehicle Control 50 1 4 505 1 Glioma Malignant Moribund Sacrifice
Nervous System Brain 100 ppm 50 22 206 730 1 Glioma Malignant Terminal Sacrifice
Nervous System Brain 300 ppm 50 50 448 528 1 Glioma Malignant Moribund Sacrifice
Nervous System Brain 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Nervous System Brain 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Nervous System Spinal Cord 100 ppm 5 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Nervous System Spinal Cord 100 ppm 5 29 241 310 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Respiratory System Larynx Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Respiratory System Lung Artery 1000 ppm 50 62 608 528 1 Schwannoma Malignant Metastatic Moribund Sacrifice
Respiratory System Lung Mediastinum 100 ppm 50 26 226 729 1 Paraganglioma Terminal Sacrifice
Respiratory System Lung 100 ppm 50 30 249 650 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung 100 ppm 50 22 209 729 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 1000 ppm 50 61 601 516 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung 1000 ppm 50 63 613 718 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung 1000 ppm 50 68 640 549 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung Vehicle Control 50 9 45 729 1 Carcinoma Metastatic Terminal Sacrifice
Respiratory System Lung 100 ppm 50 25 224 565 1 Carcinoma Metastatic Moribund Sacrifice
Respiratory System Lung 100 ppm 50 27 231 306 1 Carcinoma Metastatic Moribund Sacrifice
Respiratory System Lung Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Respiratory System Lung Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Respiratory System Lung Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Respiratory System Lung Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Respiratory System Lung 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Respiratory System Lung 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Respiratory System Lung 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Respiratory System Lung 300 ppm 50 45 425 717 1 Pheochromocytoma Malignant Metastatic Moribund Sacrifice
Respiratory System Nose Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Special Senses System Eye Iris Vehicle Control 50 8 39 729 1 Leiomyoma Terminal Sacrifice
Special Senses System Harderian Gland 300 ppm 50 47 433 730 1 Histiocytic Sarcoma Terminal Sacrifice
Special Senses System Harderian Gland 1000 ppm 50 70 647 571 1 Pheochromocytoma Malignant Metastatic Moribund Sacrifice
Special Senses System Zymbal's Gland 100 ppm 2 27 233 729 1 Adenoma Terminal Sacrifice
Special Senses System Zymbal's Gland Vehicle Control 1 7 33 618 1 Carcinoma Moribund Sacrifice
Special Senses System Zymbal's Gland 100 ppm 2 25 224 565 1 Carcinoma Moribund Sacrifice
Urinary System Kidney Renal Tubule 300 ppm 50 45 424 597 1 Adenoma Moribund Sacrifice
Urinary System Kidney Renal Tubule 300 ppm 50 46 428 655 1 Adenoma Moribund Sacrifice
Urinary System Kidney Vehicle Control 50 4 19 488 1 Leukemia Granulocytic Moribund Sacrifice
Urinary System Kidney Vehicle Control 50 6 29 661 1 Leukemia Mononuclear Moribund Sacrifice
Urinary System Kidney Vehicle Control 50 6 30 590 1 Leukemia Mononuclear Moribund Sacrifice
Urinary System Kidney Vehicle Control 50 3 15 672 1 Leukemia Mononuclear Natural Death
Urinary System Kidney 100 ppm 50 23 211 710 1 Leukemia Mononuclear Moribund Sacrifice
Urinary System Kidney 100 ppm 50 26 229 724 1 Leukemia Mononuclear Moribund Sacrifice
Urinary System Kidney 1000 ppm 50 65 622 589 1 Leukemia Mononuclear Natural Death
Urinary System Kidney 300 ppm 50 42 410 730 1 Lipoma Terminal Sacrifice
Urinary System Urinary Bladder Urothelium 300 ppm 50 48 439 528 1 Papilloma Moribund Sacrifice