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Organ Weights Individual Animal
Study Information:
Chemical Name: | Cobalt |
CASRN: | ="7440-48-4" |
Study Number: | C60311 |
Study Length (Year Completed): |
(N/A) |
Exposure Route: | RESPIRATORY EXPOSURE WHOLE BODY |
TDMS Number: | 6031105 |
Sex: | Male |
Strain and Species: | F344/N Tac Rats |
Organ Weights Individual Animal Data |
Measurement Time |
Animal Number |
Dose Group (mg/m3) |
Control Code |
Final Body Weight (g) |
Day 376 |
50 |
0 |
|
302.4 |
Day 383 |
1 |
0 |
|
396.6 |
Day 413 |
244 |
1.25 |
|
456.9 |
Day 439 |
246 |
1.25 |
|
419.3 |
Day 441 |
40 |
0 |
|
435.5 |
Day 470 |
624 |
5.0 |
|
339.2 |
Day 472 |
439 |
2.5 |
|
496.1 |
Day 478 |
631 |
5.0 |
|
335.6 |
Day 491 |
640 |
5.0 |
|
289 |
Day 514 |
39 |
0 |
|
414.8 |
Day 516 |
604 |
5.0 |
|
379 |
Day 519 |
36 |
0 |
|
440.3 |
Day 535 |
440 |
2.5 |
|
402.5 |
Day 540 |
201 |
1.25 |
|
431.4 |
Day 542 |
12 |
0 |
|
519.2 |
Day 548 |
424 |
2.5 |
|
468.4 |
Day 552 |
605 |
5.0 |
|
344.9 |
Day 561 |
637 |
5.0 |
|
341.2 |
Day 562 |
15 |
0 |
|
429.8 |
Day 562 |
242 |
1.25 |
|
421 |
Day 572 |
617 |
5.0 |
|
340.8 |
Day 572 |
650 |
5.0 |
|
331.4 |
Day 577 |
223 |
1.25 |
|
426.4 |
Day 580 |
234 |
1.25 |
|
527.1 |
Day 582 |
423 |
2.5 |
|
357.4 |
Day 583 |
21 |
0 |
|
378.9 |
Day 583 |
217 |
1.25 |
|
357.5 |
Day 583 |
427 |
2.5 |
|
338.7 |
Day 590 |
648 |
5.0 |
|
410.3 |
Day 593 |
250 |
1.25 |
|
437.6 |
Day 596 |
236 |
1.25 |
|
447.8 |
Day 598 |
48 |
0 |
|
331.2 |
Day 598 |
431 |
2.5 |
|
387.3 |
Day 603 |
235 |
1.25 |
|
364.7 |
Day 609 |
412 |
2.5 |
|
464.4 |
Day 610 |
232 |
1.25 |
|
374.7 |
Day 611 |
2 |
0 |
|
391.4 |
Day 611 |
446 |
2.5 |
|
420.6 |
Day 611 |
639 |
5.0 |
|
314.3 |
Day 613 |
31 |
0 |
|
413.9 |
Day 616 |
7 |
0 |
|
425.5 |
Day 618 |
240 |
1.25 |
|
375.7 |
Day 618 |
421 |
2.5 |
|
343.4 |
Day 618 |
436 |
2.5 |
|
355 |
Day 618 |
646 |
5.0 |
|
294.4 |
Day 619 |
621 |
5.0 |
|
290.4 |
Day 624 |
204 |
1.25 |
|
373.6 |
Day 625 |
422 |
2.5 |
|
334.3 |
Day 626 |
3 |
0 |
|
331.3 |
Day 628 |
414 |
2.5 |
|
608.5 |
Day 628 |
603 |
5.0 |
|
300.4 |
Day 634 |
216 |
1.25 |
|
344.7 |
Day 641 |
243 |
1.25 |
|
494.4 |
Day 646 |
415 |
2.5 |
|
357 |
Day 646 |
606 |
5.0 |
|
296.5 |
Day 646 |
638 |
5.0 |
|
326.3 |
Day 652 |
408 |
2.5 |
|
480.2 |
Day 652 |
438 |
2.5 |
|
467.2 |
Day 652 |
632 |
5.0 |
|
307.4 |
Day 654 |
425 |
2.5 |
|
294.3 |
Day 654 |
442 |
2.5 |
|
351.2 |
Day 660 |
630 |
5.0 |
|
350.9 |
Day 660 |
649 |
5.0 |
|
308.6 |
Day 663 |
11 |
0 |
|
447.1 |
Day 663 |
33 |
0 |
|
354.9 |
Day 663 |
222 |
1.25 |
|
296.5 |
Day 663 |
249 |
1.25 |
|
334.4 |
Day 667 |
220 |
1.25 |
|
347.1 |
Day 667 |
221 |
1.25 |
|
397.1 |
Day 667 |
403 |
2.5 |
|
318.4 |
Day 668 |
24 |
0 |
|
493 |
Day 670 |
46 |
0 |
|
393.2 |
Day 674 |
219 |
1.25 |
|
508.9 |
Day 675 |
43 |
0 |
|
455.3 |
Day 675 |
208 |
1.25 |
|
406.8 |
Day 675 |
241 |
1.25 |
|
327.6 |
Day 676 |
9 |
0 |
|
403.8 |
Day 678 |
49 |
0 |
|
330.5 |
Day 678 |
445 |
2.5 |
|
331.5 |
Day 679 |
609 |
5.0 |
|
309.6 |
Day 680 |
437 |
2.5 |
|
304.3 |
Day 682 |
32 |
0 |
|
427.1 |
Day 682 |
6 |
0 |
|
426.9 |
Day 683 |
20 |
0 |
|
396 |
Day 683 |
206 |
1.25 |
|
415.4 |
Day 683 |
406 |
2.5 |
|
386.5 |
Day 684 |
212 |
1.25 |
|
315 |
Day 684 |
224 |
1.25 |
|
317.6 |
Day 688 |
17 |
0 |
|
364.9 |
Day 688 |
25 |
0 |
|
320.1 |
Day 688 |
410 |
2.5 |
|
297.8 |
Day 688 |
418 |
2.5 |
|
305.8 |
Day 688 |
642 |
5.0 |
|
267.7 |
Day 689 |
429 |
2.5 |
|
401.8 |
Day 689 |
618 |
5.0 |
|
263.9 |
Day 689 |
626 |
5.0 |
|
276.9 |
Day 691 |
35 |
0 |
|
372 |
Day 691 |
602 |
5.0 |
|
315.5 |
Day 691 |
620 |
5.0 |
|
333.9 |
Day 696 |
42 |
0 |
|
359.1 |
Day 696 |
645 |
5.0 |
|
286.6 |
Day 697 |
4 |
0 |
|
375.6 |
Day 698 |
426 |
2.5 |
|
311.8 |
Day 698 |
610 |
5.0 |
|
247.2 |
Day 699 |
215 |
1.25 |
|
317.5 |
Day 702 |
22 |
0 |
|
399.6 |
Day 702 |
641 |
5.0 |
|
256.4 |
Day 702 |
647 |
5.0 |
|
288.6 |
Day 703 |
413 |
2.5 |
|
401.2 |
Day 704 |
447 |
2.5 |
|
414.4 |
Day 705 |
18 |
0 |
|
402.8 |
Day 705 |
239 |
1.25 |
|
383.7 |
Day 705 |
402 |
2.5 |
|
336.7 |
Day 705 |
449 |
2.5 |
|
284.5 |
Day 708 |
205 |
1.25 |
|
431.2 |
Day 713 |
612 |
5.0 |
|
289.4 |
Day 715 |
231 |
1.25 |
|
300.7 |
Day 715 |
629 |
5.0 |
|
334.7 |
Day 716 |
432 |
2.5 |
|
316.6 |
Day 716 |
444 |
2.5 |
|
283.2 |
Day 717 |
608 |
5.0 |
|
285.1 |
Day 717 |
619 |
5.0 |
|
265.9 |
Day 719 |
23 |
0 |
|
330.8 |
Day 719 |
248 |
1.25 |
|
355 |
Day 719 |
401 |
2.5 |
|
293.8 |
Day 721 |
409 |
2.5 |
|
297.2 |
Day 722 |
613 |
5.0 |
|
285.9 |
Day 723 |
611 |
5.0 |
|
280.6 |
Day 724 |
47 |
0 |
|
369.7 |
Day 725 |
420 |
2.5 |
|
375 |
Day 727 |
38 |
0 |
|
371.6 |
Day 729 |
10 |
0 |
|
335.6 |
Day 729 |
14 |
0 |
|
415.1 |
Day 729 |
16 |
0 |
|
426.2 |
Day 729 |
27 |
0 |
|
551 |
Day 729 |
28 |
0 |
|
517.9 |
Day 729 |
29 |
0 |
|
465 |
Day 729 |
30 |
0 |
|
302.6 |
Day 729 |
34 |
0 |
|
552.6 |
Day 729 |
37 |
0 |
|
467.8 |
Day 729 |
41 |
0 |
|
476.1 |
Day 729 |
45 |
0 |
|
438.9 |
Day 729 |
5 |
0 |
|
438.8 |
Day 729 |
203 |
1.25 |
|
485 |
Day 729 |
207 |
1.25 |
|
425.8 |
Day 729 |
209 |
1.25 |
|
499.7 |
Day 729 |
210 |
1.25 |
|
479.6 |
Day 729 |
211 |
1.25 |
|
396.9 |
Day 729 |
214 |
1.25 |
|
430.1 |
Day 729 |
225 |
1.25 |
|
476.3 |
Day 729 |
226 |
1.25 |
|
461.6 |
Day 729 |
227 |
1.25 |
|
311.5 |
Day 729 |
228 |
1.25 |
|
485.6 |
Day 729 |
233 |
1.25 |
|
486.2 |
Day 729 |
237 |
1.25 |
|
445.5 |
Day 729 |
238 |
1.25 |
|
480.2 |
Day 729 |
247 |
1.25 |
|
430.8 |
Day 729 |
404 |
2.5 |
|
443.8 |
Day 729 |
405 |
2.5 |
|
457.9 |
Day 729 |
407 |
2.5 |
|
392.8 |
Day 729 |
416 |
2.5 |
|
433.3 |
Day 729 |
428 |
2.5 |
|
418.6 |
Day 729 |
430 |
2.5 |
|
378.3 |
Day 729 |
433 |
2.5 |
|
399.2 |
Day 729 |
441 |
2.5 |
|
376.8 |
Day 729 |
448 |
2.5 |
|
350 |
Day 729 |
614 |
5.0 |
|
361.8 |
Day 729 |
615 |
5.0 |
|
338.1 |
Day 729 |
616 |
5.0 |
|
335.7 |
Day 729 |
622 |
5.0 |
|
257.1 |
Day 729 |
623 |
5.0 |
|
375.9 |
Day 729 |
625 |
5.0 |
|
426 |
Day 729 |
627 |
5.0 |
|
323.4 |
Day 729 |
628 |
5.0 |
|
319 |
Day 729 |
633 |
5.0 |
|
334.2 |
Day 729 |
634 |
5.0 |
|
359.4 |
Day 729 |
643 |
5.0 |
|
309.9 |
Day 729 |
644 |
5.0 |
|
314.5 |
Day 730 |
13 |
0 |
|
535 |
Day 730 |
19 |
0 |
|
488.2 |
Day 730 |
26 |
0 |
|
462.5 |
Day 730 |
44 |
0 |
|
461.6 |
Day 730 |
8 |
0 |
|
512.3 |
Day 730 |
202 |
1.25 |
|
418.8 |
Day 730 |
213 |
1.25 |
|
428.8 |
Day 730 |
218 |
1.25 |
|
511 |
Day 730 |
229 |
1.25 |
|
471.2 |
Day 730 |
230 |
1.25 |
|
289.9 |
Day 730 |
245 |
1.25 |
|
430.5 |
Day 730 |
411 |
2.5 |
|
471.7 |
Day 730 |
417 |
2.5 |
|
366.2 |
Day 730 |
419 |
2.5 |
|
397.4 |
Day 730 |
434 |
2.5 |
|
337.6 |
Day 730 |
435 |
2.5 |
|
422.4 |
Day 730 |
443 |
2.5 |
|
374.3 |
Day 730 |
450 |
2.5 |
|
457.7 |
Day 730 |
601 |
5.0 |
|
349.9 |
Day 730 |
607 |
5.0 |
|
301.7 |
Day 730 |
635 |
5.0 |
|
338.5 |
Day 730 |
636 |
5.0 |
|
299.5 |
Abbreviations: |
NA: Not Available
|