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National Institute of Environmental Health Sciences

 

Person Details

Superfund Research Program

Bruce D. Hammock

University of California-Davis
Department of Entomology
90 Briggs Hall
One Shields Avenue
Davis, CA 95616
Phone: 530-752-7519
Fax: 530-752-1537
Email:

Projects

Research Briefs

Patents

  • Use of Inhibitors of Soluble Expoxide Hydrolase to Synergize Activity of COX and 5-LOX Inhibitors
  • Linoleic acid diol and glucuronide conjugate levels as diagnostic markers of disorders of abnormal regulation of cytochrome P450 metabolism of unsaturated fatty acids
  • Epoxide hydrolase inhibitor methods
  • Epoxide hydrolase complexes and methods therewith
  • Modulation of bioactive epoxy-fatty acid levels by phosphodiesterase inhibitors
  • Compact assay system with digital information
  • Enzyme amplified, complex linked, competitive and non-competitive assays for the detection of metal ions
  • Recombinant soluble epoxide hydrolase
  • Cyanohydrin ethers and esters as high-sensitivity enzyme substrates
  • Diagnostic microarray apparatus
  • Acyl Piperidine Inhibitors of Soluble Epoxide Hydrolase
  • Sorafenib derivatives as p21 inhibitors
  • Treatment of inflammatory disorders in non-human mammals
  • Sorafenib derivatives as sEH inhibitors
  • Preparation of Novel 1,3-Substituted Ureas as Inhibitors of Soluble Epoxide Hydrolase
  • Inhibitor of apoptosis proteins and nucleic acids and methods for making and using them
  • Inhibition of glutathione transferase by haloenol lactones
  • Inhibition of glutathione transferase by haloenol lactones
  • Inhibitors of epoxide hydrolases for the treatment of hypertension

Superfund Sites

Frontier Fertilizer

  • University of California-Davis: Immunoassays for Human and Environmental Monitoring

Sulphur Bank Mercury Mine

  • University of California-Davis: Immunoassays for Human and Environmental Monitoring

Publications

2014
  • Charles, Rebecca L., Olena Rudyk, Oleksandra Prysyazhna, Alisa Kamynina, Jun Yang, Christophe Morisseau, Bruce D. Hammock, Bruce A. Freeman, and Philip Eaton. 2014. Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   111(22):8167-8172. doi:10.1073/pnas.1402965111  
  • Kujal, Petr, Vera C. Chabova, Petra Skaroupkova, Zuzana Huskova, Zdena Vernerova, Herbert J. Kramer, Agnieszka Walkowska, Elzbieta Kompanowska-Jezierska, Janusz Sadowski, Kento Kitada, Akira Nishiyama, Sung Hee Hwang, Bruce D. Hammock, John D. Imig, and Ludek Cervenka. 2014. Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clinical and Experimental Pharmacology and Physiology. 41(3):227-237. doi:10.1111/1440-1681.12204  
  • Schuchardt, Jan Philipp, Simone Schmidt, Gaby Kressel, Ina Willenberg, Bruce D. Hammock, Andreas Hahn, and Nils Helge Schebb. 2014. Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men. Prostaglandins, Leukotrienes and Essential Fatty Acids. 90:27-37. doi:10.1016/j.plefa.2013.12.008  
  • Thiphom, Sarunya, Tippawan Prapamontol, Somporn Chantara, Ampica Mangklabruks, Chaisuree Suphavilai, Ki Chang Ahn, Shirley J. Gee, and Bruce D. Hammock. 2014. Determination of the pyrethroid insecticide metabolite 3-PBA in plasma and urine samples from farmer and consumer groups in northern Thailand. Journal of Environmental Science and Health, Part B.   49(1):15-22. doi:10.1080/03601234.2013.836862  
  • Trunnelle, Kelly J., Deborah H. Bennett, Ki Chang Ahn, Marc B. Schenker, Daniel J. Tancredi, Shirley J. Gee, Maria T. Stoecklin-Marois, and Bruce D. Hammock. 2014. Concentrations of the urinary pyrethroid metabolite 3-phenoxybenzoic acid in farm worker families in the MICASA study. Environmental Research.   131:153-159. doi:10.1016/j.envres.2014.03.003  
  • Ulu, Arzu, Stephen Lee, Christina Miyabe, Jun Yang, Bruce G. Hammock, Hua Dong, and Bruce D. Hammock. 2014. An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II dependent hypertension. Journal of Cardiovascular Pharmacology. doi:10.1097/fjc.0000000000000094  
  • Wecksler, Aaron T., Sung Hee Hwang, Hiromi I. Wettersten, Jennifer E. Gilda, Amy Patton, Leonardo J. Leon, Kermit L. Carraway, Aldrin V. Gomes, Keith Baar, Robert H. Weiss, and Bruce D. Hammock. 2014. Novel sorafenib-based structural analogues: In-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anti-Cancer Drugs. 25(4):433-446. doi:10.1097/CAD.0000000000000079  
  • Zhang, Guodong, Sean D. Kodani, and Bruce D. Hammock. 2014. Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer. Progress in Lipid Research. 53:108-123. doi:10.1016/j.plipres.2013.11.003  
2013
  • Bettaieb, Ahmed, Naoto Nagata, Daniel AbouBechara, Samah Chahed, Christophe Morisseau, Bruce D. Hammock, and Fawaz G. Haj. 2013. Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue. Journal of Biological Chemistry.   288:14189-14199. doi:10.1074/jbc.M113.458414  
  • Chen, Ting, Khuloud Takrouri, Sung Hee-Hwang, Sandeep Rana, Revital Yefidoff-Freedman, Jose Halperin, Amarnath Natarajan, Christophe Morisseau, Bruce D. Hammock, Michael Chorev, and Bertal H. Aktas. 2013. Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase. Journal of Medicinal Chemistry.   56(23):9457-9470. doi:10.1021/jm400793v  
  • Falck, David, Nils Helge Schebb, Setyo Prihatiningtyas, Jiawen Zhang, Ferry Heus, Christophe Morisseau, Jeroen Kool, Bruce D. Hammock, and Wilfried MA Niessen. 2013. Development of on-line liquid chromatography-biochemical detection for soluble epoxide hydrolase inhibitors in mixtures. Chromatographia. 76:13-21. doi:10.1007/s10337-012-2343-0  
  • Frolov, Andrey, Hua Dong, Min Jiang, Lihua Yang, Erik C. Cook, Rahul Matnani, Bruce D. Hammock, and Leslie J. Crofford. 2013. Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis. Journal of Biological Chemistry.   288:23696-23703. doi:10.1074/jbc.M112.445916  
  • Frolov, Andrey, Lihua Yang, Hua Dong, Bruce D. Hammock, and Leslie J. Crofford. 2013. Anti-inflammatory properties of prostaglandin E2: Deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice. Prostaglandins, Leukotrienes and Essential Fatty Acids. 89(5):351-358. doi:10.1016/j.plefa.2013.08.003  
  • Gardell, Alison M., Jun Yang, Romina Sacchi, Nann A. Fangue, Bruce D. Hammock, and Dietmar Kultz. 2013. Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis. Journal of Experimental Biology. 216(24):4615-4625. doi:10.1242/​jeb.088906  
  • Guedes, Alonso G P., Christophe Morisseau, Albert Sole, Joao H N. Soares, Arzu Ulu, Hua Dong, and Bruce D. Hammock. 2013. Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis. Veterinary Anaesthesia and Analgesia. 40(4):440-448. doi:10.1111/vaa.12030  
  • Han, Jin-Hee, Hee-Joo Kim, L. Sudheendra, Shirley J. Gee, Bruce D. Hammock, and Ian M. Kennedy. 2013. Photonic crystal lab-on-a-chip for detecting staphylococcal entertoxin B at low attomolar concentration. Analytical Chemistry.   85(6):3104-3109. doi:10.1021/ac303016h  
  • Han, Jin-Hee, Hee-Joo Kim, L. Sudheendra, Elizabeth A. Hass, Shirley J. Gee, Bruce D. Hammock, and Ian M. Kennedy. 2013. Electrophoretic build-up of multi nanoparticle array for a highly sensitive immunoassay. Biosensors & Bioelectronics.   41:302-308. doi:10.1016/j.bios.2012.08.042  
  • Hwang, Sung Hee, Aaron T. Wecksler, Karen M. Wagner, and Bruce D. Hammock. 2013. Rationally designed multitarget agents against inflammation and pain. Current Medicinal Chemistry. 20(13):1783-1799. doi:10.2174/0929867311320130013  
  • Hwang, Sung Hee, Aaron T. Wecksler, Guodong Zhang, Christophe Morisseau, Long V. Nguyen, Samuel H. Fu, and Bruce D. Hammock. 2013. Synthesis and biological evaluation of sorafenib- and regorafenib- like sEH inhibitors. Bioorganic & Medicinal Chemistry Letters. 23(13):3732-3737. doi:10.1016/j.bmcl.2013.05.011  
  • Inceoglu, Bora, Dorota Zolkowska, Hyun Ju Yoo, Karen M. Wagner, Jun Yang, Edward Hackett, Sung Hee Hwang, Kin Sing S. Lee, Michael A. Rogawski, Christophe Morisseau, and Bruce D. Hammock. 2013. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. PLoS ONE.   8(12):doi:10.1371/journal.pone.0080922  
  • Kamita, Shizou G., Grant H. Oshita, Peng Wang, Christophe Morisseau, Bruce D. Hammock, Raja Sekhar Nandety, and Bryce W. Falk. 2013. Characterization of HOVI-MEH1, a microsomal epoxide hydrolase from the Glassy-Winged Sharpshooter Homalodisca vitripennis. Archives of Insect Biochemistry and Physiology. 83(4):171-179. doi:10.1002/arch.21100  
  • Kamita, Shizou G., Kohji Yamamoto, Mary M. Dadala, Khavong Pha, Christophe Morisseau, Aurélie Escaich, and Bruce D. Hammock. 2013. Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens. Insect Biochemistry and Molecular Biology. 43(3):219-228. doi:10.1016/j.ibmb.2012.12.002  
  • Lee, Kin Sing S., Christophe Morisseau, Jun Yang, Peng Wang, Sung Hee Hwang, and Bruce D. Hammock. 2013. Forster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase. Analytical Biochemistry.   434(2):259-268. doi:10.1016/j.ab.2012.11.015  
  • Liu, Jun-Yan, Yanping Lin, Hong Qiu, Christophe Morisseau, Tristan E. Rose, Sung Hee Hwang, Nipavan Chiamvimonvat, and Bruce D. Hammock. 2013. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. European Journal of Pharmaceutical Sciences. 48(4-5):619-627. doi:10.1016/j.ejps.2012.12.013  
  • Morisseau, Christophe and Bruce D. Hammock. 2013. Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. Annual Review of Pharmacology and Toxicology.   53:37-58. doi:10.1146/annurev-pharmtox-011112-140244  
  • Morisseau, Christophe, Svitlana Pakhomova, Sung Hee Hwang, Marcia E. Newcomer, and Bruce D. Hammock. 2013. Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorganic & Medicinal Chemistry Letters. 23(13):3818-3821. doi:10.1016/j.bmcl.2013.04.083  
  • Morisseau, Christophe, Sunil Sahdeo, Gino A. Cortopassi, and Bruce D. Hammock. 2013. Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries. Analytical Biochemistry.   434(1):105-111. doi:10.1016/j.ab.2012.11.017  
  • Nording, Malin L., Jun Yang, Katrin Georgi, Christine H. Karbowski, J. Bruce German, Robert H. Weiss, Ronald J. Hogg, Johan Trygg, Bruce D. Hammock, and Angela M. Zivkovic. 2013. Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. PLoS ONE.   8:e76575. doi:10.1371/journal.pone.0076575  
  • Panigrahy, Dipak, B.T. Kalish, S. Huang, D.R. Bielenberg, H.D. Le, J. Yang, M.L. Edin, Craig R. Lee, O. Benny, D.K. Mudge, C.E. Butterfield, A. Mammoto, T. Mammoto, Bora Inceoglu, R.L. Jenkins, M.A. Simpson, T. Akino, F.B. Lih, Kenneth B. Tomer, D.E. Ingber, Bruce D. Hammock, J.R. Falck, Vijay L. Manthati, A. Kaipainen, P.A. D'Amore, M. Puder, Darryl C. Zeldin, and Mark W. Kieran. 2013. Epoxyeicosanoids promote organ and tissue regeneration. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   110(33):13528-13533. doi:10.1073/pnas.1311565110  
  • Poli, Giorgio, Erica Corda, Piera Anna Martino, Paola Dall'Ara, Silvio R. Bareggi, Giampietro Bondiolotti, Barbara Iulini, Maria Mazza, Cristina Casalone, Sung Hee Hwang, Bruce D. Hammock, and Bora Inceoglu. 2013. Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie. Life Sciences.   92(23):1145-1150. doi:10.1016/j.lfs.2013.04.014  
  • Ranganathan, Anupama, Grace A. Paradise, Chad A. Hansen, Mark R. McCoy, Shirley J. Gee, Ping Zhong, Dan Chang, and Bruce D. Hammock. 2013. Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. Journal of Agricultural and Food Chemistry.   61(28):6964-6970. doi:10.1021/jf401302y  
  • Schuchardt, Jan Philipp, Simone Schmidt, Gaby Kressel, Hua Dong, Ina Willenberg, Bruce D. Hammock, Andreas Hahn, and Nils Helge Schebb. 2013. Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. Prostaglandins, Leukotrienes and Essential Fatty Acids. 89(1):19-29. doi:10.1016/j.plefa.2013.04.001  
  • Sirish, Padmini, Ning Li, Jun-Yan Liu, Kin Sing S. Lee, Sung Hee Hwang, Hong Qiu, Cuifen Zhao, Siu Mei Ma, Javier E. Lopez, Bruce D. Hammock, and Nipavan Chiamvimonvat. 2013. Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   110(14):5618-5623. doi:10.1073/pnas.1221972110  
  • Smilowitz, Jennifer T., Angela M. Zivkovic, Yu-Jui Y. Wan, Steven M. Watkins, Malin Nording, Bruce D. Hammock, and J. Bruce German. 2013. Nutritional lipidomics: Molecular metabolism, analytics, and diagnostics. Molecular Nutrition & Food Research. 57(8):1319-1335. doi:10.1002/mnfr.201200808  
  • Stewart, Daniel N., Jozsef Lango, Krishnan P. Nambiar, Miranda J S. Falso, Paul G. Fitzgerald, David M. Rocke, Bruce D. Hammock, and Bruce A. Buchholz. 2013. Carbon turnover in the water-soluble protein of the adult human lens. Molecular Vision. 19:463-475.
  • Trunnelle, Kelly J., Deborah H. Bennett, Daniel J. Tancredi, Shirley J. Gee, Maria T. Stoecklin-Marois, T.E. Hennessy-Burt, Bruce D. Hammock, and Marc B. Schenker. 2013. Pyrethroids in house dust from the homes of farm worker families in the MICASA study. Environment International.   61:57-63. doi:10.1016/j.envint.2013.09.007  
  • Ulu, Arzu, Todd R. Harris, Christophe Morisseau, Christina Miyabe, Hiromi Inoue, Gertrud Schuster, Hua Dong, Ana-Maria Iosif, Jun-Yan Liu, Robert H. Weiss, Nipavan Chiamvimonvat, John D. Imig, and Bruce D. Hammock. 2013. Anti-inflammatory effects of omega-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II dependent hypertension. Journal of Cardiovascular Pharmacology. 62(3):285-297. doi:10.1097/FJC.0b013e318298e460  
  • Van Bogaert, I., Guodong Zhang, J. Yang, Jun-Yan Liu, Y. Ye, W. Soetaert, and Bruce D. Hammock. 2013. Preparation of 20- HETE using multifunctional enzyme type 2-negative Starmerella bombicola. Journal of Lipid Research.   54(11):3215-3219. doi:10.1194/jlr.D042226  
  • Vanrell, L., A. Gonzalez-Techera, Bruce D. Hammock, and Gualberto G. Gonzalez-Sapienza. 2013. Nanopeptamers for the development of small-analyte lateral flow tests with a positive readout. Analytical Chemistry.   85(2):1177-1182. doi:10.1021/ac3031114  
  • Wagner, Karen M., Bora Inceoglu, Hua Dong, Jun Yang, Sung Hee Hwang, Paul D. Jones, Christophe Morisseau, and Bruce D. Hammock. 2013. Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models. European Journal of Pharmacology. 700(1-3):93-101. doi:10.1016/j.ejphar.2012.12.015  
  • Wang, Yanru, Peiwu Li, Zuzana Majkova, Candace Bever, Hee-Joo Kim, Qi Zhang, Julie E. Dechant, Shirley J. Gee, and Bruce D. Hammock. 2013. Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay. Analytical Chemistry.   85(17):8298-8303. doi:10.1021/ac4015885  
  • Wang, Yanru, Hong Wang, Peiwu Li, Qi Zhang, Hee-Joo Kim, Shirley J. Gee, and Bruce D. Hammock. 2013. Phage-displayed peptide that mimics aflatoxins and its application in immunoassay. Journal of Agricultural and Food Chemistry.   61(10):2426–2433. doi:10.1021/jf4004048  
  • Wang, Yanru, Hong Wang, Peiwu Li, Qi Zhang, Hee-Joo Kim, Shirley J. Gee, and Bruce D. Hammock. 2013. Correction to: Phage- displayed peptide that mimics aflatoxins and its application in immunoassay. Journal of Agricultural and Food Chemistry.   61(16):3994-3994. doi:10.1021/jf401235p  
  • Wettersten, Hiromi I., Sung Hee Hwang, Cuiwen Li, Eunice Y. Shiu, Aaron T. Wecksler, Bruce D. Hammock, and Robert H. Weiss. 2013. A novel p21 attenuator which is structurally related to sorafenib. Cancer Biology & Therapy. 14:278-285. doi:10.4161/cbt.23374  
  • Yang, J., P. Solaimani, Hua Dong, Bruce D. Hammock, and O. Hankinson. 2013. Treatment of mice with 2,3,7,8- Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung. Toxicological Sciences. 38(6):833-836.
  • Zhang, Guodong, Dipak Panigrahy, Lisa M. Mahakian, Jun Yang, Jun-Yan Liu, Kin Sing S. Lee, Hiromi I. Wettersten, Arzu Ulu, Xiaowen Hu, Sarah Tam, Sung Hee Hwang, Elizabeth S. Ingham, Mark W. Kieran, Robert H. Weiss, Katherine W. Ferrara, and Bruce D. Hammock. 2013. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   110(16):6530-6535. doi:10.1073/pnas.1304321110  
  • Zhang, Wanying, Haonan Li, Hua Dong, Jie Liao, Bruce D. Hammock, and Guang-Yu Yang. 2013. Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice. Anticancer Research.   33(12):5261-5271.
2012
  • Ahn, Ki Chang, Takeo Kasagami, Hsing-Ju Tsai, Nils Helge Schebb, Temitope A. Ogunyoku, Shirley J. Gee, Thomas M. Young, and Bruce D. Hammock. 2012. An Immunoassay to Evaluate Human/Environmental Exposure to the Antimicrobial Triclocarban. Environmental Science & Technology.   46:374-381. doi:10.1021/es202494d   (Completed with ARRA Funds)
  • Cao, Zhengyu, Bruce D. Hammock, Mark R. McCoy, Michael A. Rogawski, Pamela J. Lein, and Isaac N. Pessah. 2012. Tetramethylenedisulfotetramine alters Ca2+ dynamics in cultured hippocampal neurons: Mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicological Sciences.   130(2):362-372. doi:10.1093/toxsci/kfs244  
  • Cherednichenko, Gennady, Rong Zhang, Roger A. Bannister, Valeriy Timofeyev, N. Li, Erika B. Fritsch, Wei Feng, G. Barrientos, Nils Helge Schebb, Bruce D. Hammock, Kurt G. Beam, Nipavan Chiamvimonvat, and Isaac N. Pessah. 2012. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   109(35):14158-14163. doi:10.1073/pnas.1211314109  
  • Eiserich, Jason P., J. Yang, Brian M. Morrissey, Bruce D. Hammock, and Carroll E. Cross. 2012. Omics approaches in cystic fibrosis research: A focus on oxylipin profiling in airway secretions. Annals of the New York Academy of Sciences.   1259:1-9. doi:10.1111/j.1749-6632.2012.06580.x  
  • Han, Jin-Hee, L. Sudheendra, Hee-Joo Kim, Shirley J. Gee, Bruce D. Hammock, and Ian M. Kennedy. 2012. Ultrasensitive on-chip immunoassays with a nanoparticle-assembled photonic crystal. ACS Nano. 6(10):8570-8582. doi:10.1021/nn301656c  
  • Inceoglu, Ahmet B., Heather L. Clifton, Jun Yang, Christine Hegedus, Bruce D. Hammock, and Saul Schaefer. 2012. Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice. Journal of Cardiovascular Pharmacology. 60:70-75. doi:10.1097/FJC.0b013e3182580a5d  
  • Inceoglu, Bora, Karen M. Wagner, Jun Yang, Ahmed Bettaieb, Nils Helge Schebb, Sung Hee Hwang, Christophe Morisseau, Fawaz G. Haj, and Bruce D. Hammock. 2012. Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of Type I Diabetes. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   109(28):11390-11395. doi:10.1073/pnas.1208708109  
  • Kim, Hee-Joo, Zuzana Majkova, Julie E. Dechant, Shirley J. Gee, Sofia Tabares-da Rosa, Gualberto G. Gonzalez-Sapienza, Bruce D. Hammock, and Mark R. McCoy. 2012. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Analytical Chemistry.   84(2):1165-1171. doi:10.1021/ac2030255  
  • Kim, Hee-Joo, Mark R. McCoy, Zuzana Majkova, Julie E. Dechant, Shirley J. Gee, Sofia Tabares-da Rosa, Gualberto G. Gonzalez-Sapienza, and Bruce D. Hammock. 2012. Correction to isolation of alpaca antihapten heavy chain single domain antibodies for development of sensitive immunioassay. Analytical Chemistry.   84(15):6919–6919. doi:10.1021/ac301927h  
  • Kim, In-Hae, Kosuke Nishi, Takeo Kasagami, Christophe Morisseau, Jun-Yan Liu, Hsing-Ju Tsai, and Bruce D. Hammock. 2012. Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry Letters. 22(18):5889-5892. doi:10.1016/j.bmcl.2012.07.074  
  • Lin, Yanping, John L. Ubels, Mark P. Schotanus, Zhaohong Yin, Victorina Pintea, Bruce D. Hammock, and Mitchell A. Watsky. 2012. Enhancement of vitamin D metabolites in the eye following vitamin D3 supplementation and UV-B irradiation. Current Eye Research. 37(10):871-878. doi:10.3109/02713683.2012.688235  
  • McCoy, Mark R., Zheng Yang, Xun Fu, Ki Chang Ahn, Shirley J. Gee, David C. Bom, Ping Zhong, Dan Chang, and Bruce D. Hammock. 2012. Monitoring of total type II pyrethroid pesticides in citrus oils and water by converting to a common product 3-phenoxybenzoic acid. Journal of Agricultural and Food Chemistry.   60:5065-5070. doi:10.1021/jf2051653  
  • Morisseau, Christophe, Nils Helge Schebb, Hua Dong, Arzu Ulu, Pavel A. Aronov, and Bruce D. Hammock. 2012. Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids. Biochemical and Biophysical Research Communications.   419:796-800. doi:10.1016/j.bbrc.2012.02.108  
  • Qiu, Hong, Jun-Yan Liu, Dongguang Wei, Ning Li, Ebenezer N. Yamoah, Bruce D. Hammock, and Nipavan Chiamvimonvat. 2012. Cardiac-generated prostanoids mediate cardiac myocyte apoptosis after myocardial ischaemia. Cardiovascular Research. 95(3):336-345. doi:10.1093/cvr/cvs191  
  • Schebb, Nils Helge, Ki Chang Ahn, Hua Dong, Shirley J. Gee, and Bruce D. Hammock. 2012. Whole blood is the sample matrix of choice for monitoring systemic triclocarbon levels. Chemosphere.   87(7):825-827. doi:10.1016/j.chemosphere.2011.12.077   (Completed with ARRA Funds)
  • Schebb, Nils Helge, Bruce A. Buchholz, Bruce D. Hammock, and Robert H. Rice. 2012. Metabolism of the antibacterial triclocarban by human epidermal keratinocytes to yield protein adducts. Journal of Biochemical and Molecular Toxicology.   26(6):230-234. doi:10.1002/jbt.21411  
  • Schebb, Nils Helge, B. Franze, R. Maul, Anupama Ranganathan, and Bruce D. Hammock. 2012. In Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative Metabolites. Drug Metabolism and Disposition.   40:25-31. (Completed with ARRA Funds)
  • Thiphom, Sarunya, Tippawan Prapamontol, Somporn Chantara, Ampica Mangklabruks, Chaisuree Suphavilai, Ki Chang Ahn, Shirley J. Gee, and Bruce D. Hammock. 2012. An enzyme-linked immunosorbent assay for detecting 3-phenoxybenzoic acid in plasma and its application to farmers and consumers. Analytical Methods.   4:3772-3778. doi:10.1039/c2ay25642h  
  • Yang, Jun, Jason P. Eiserich, Carroll E. Cross, Brian M. Morrissey, and Bruce D. Hammock. 2012. Metabolomic profiling of regulatory lipid mediators in sputum from adult cystic fibrosis patients. Free Radical Biology and Medicine.   53(1):160-171. doi:10.1016/j.freeradbiomed.2012.05.001  
  • Yao, Hongwei, Jun-Yan Liu, Aman I. Samra, Shizou G. Kamita, Anthony J. Cornel, Bruce D. Hammock, and Huazhang Huang. 2012. Development of pyrethroid-like fluorescent substrates for glutathione S-transferase. Analytical Biochemistry.   431:77-83. doi:10.1016/j.ab.2012.09.011  
  • Yueh, Mei-Fei F., Tao Li, Ronald M. Evans, Bruce D. Hammock, and Robert H. Tukey. 2012. Triclocarban Mediates Induction of Xenobiotic Metabolism through Activation of the Constitutive Androstane Receptor and the Estrogen Receptor Alpha. PLoS ONE.   7(6):e37705. doi:10.1371/journal.pone.0037705   (Completed with ARRA Funds)
  • Zhang, Wanying, Allison L. Yang, Jie Liao, Haonan Li, Hua Dong, Yeon Tae Chung, Han Bai, Kristina A. Matkowskyj, Bruce D. Hammock, and Guang-Yu Yang. 2012. Soluble epoxide hydrolase gene deficiency or inhibition attenuates chronic active inflammatory bowel disease in IL-10(-/-) mice. Digestive Diseases and Sciences. 57(10):2580-2591. doi:10.1007/s10620-012-2217-1  
  • Zivkovic, Angela M., Jun Yang, Katrin Georgi, Christine Hegedus, Malin L. Nording, Aifric O'Sullivan, J. Bruce German, Ronald J. Hogg, Robert H. Weiss, Curt Bay, and Bruce D. Hammock. 2012. Serum oxylipin profiles in lgA nephropathy patients reflect kidney functional alterations. Metabolomics.   8(6):1102-1113. doi:10.1007/s11306-012-0417-5  
  • Zolkowska, Dorota, Christopher N. Banks, Ashish Dhir, Bora Inceoglu, James R. Sanborn, Mark R. McCoy, Donald A. Bruun, Bruce D. Hammock, Pamela J. Lein, and Michael A. Rogawski. 2012. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. Journal of Pharmacology and Experimental Therapeutics.   341(2):435-446. doi:10.1124/jpet.111.190579  
2011
  • Abdu, Emun, Donald A. Bruun, Dongren R. Yang, Jun Yang, Bora Inceoglu, Bruce D. Hammock, Nabil J. Alkayed, and Pamela J. Lein. 2011. Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures. Journal of Neurochemistry.   117:632-642. doi:10.1111/j.1471-4159.2010.07139.x  
  • Ahn, Ki Chang, Shirley J. Gee, Pavel A. Aronov, Helen Vega, Robert I. Krieger, Bruce D. Hammock, and Hee-Joo Kim. 2011. Immunochemical analysis of 3-phenoxybenzoic acid, a biomarker of forestry worker exposure to pyrethroid insecticides. Analytical and Bioanalytical Chemistry.   401(4):1285-1293. doi:10.1007/s00216-011-5184-z  
  • Ahn, Ki Chang, Hee-Joo Kim, Mark R. McCoy, Shirley J. Gee, and Bruce D. Hammock. 2011. Immunoassays and biosensors for monitoring environmental and human exposure to pyrethroid insecticides. Journal of Agricultural and Food Chemistry.   59(7):2792-2802. doi:10.1021/jf1033569  
  • Barhoumi, Rola, Youssef Mouneimne, Bruce D. Hammock, Stephen H. Safe, Alan R. Parrish, Robert C. Burghardt, and Ernesto Ramos. 2011. Multiphoton spectral analysis of benzo a pyrene uptake and metabolism in a rat liver cell line. Toxicology and Applied Pharmacology.   253:45-56. doi:10.1016/j.taap.2011.03.009  
  • Charles, Rebecca L., Joseph R. Burgoyne, Manuel Mayr, Steven M. Weldon, Norbert Hubner, Hua Dong, Christophe Morisseau, Bruce D. Hammock, Aimee Landar, and Philip Eaton. 2011. Redox regulation of soluble epoxide hydrolase by 15-Deoxy-AProstaglandin J2 controls coronary hypoxic vasodilation. Circ. Res. Circulation Research.   108:324-334. doi:10.1161/CIRCRESAHA.110.235879  
  • Davis, Benjamin B., Jun-Yan Liu, Daniel J. Tancredi, L. Wang, S.I. Simon, Bruce D. Hammock, and Kent E. Pinkerton. 2011. The anti-inflammatory effects of soluble epoxide hydrolase inhibitors are independent of leukocyte recruitment. Biochemical and Biophysical Research Communications.   410:494-500.
  • Gee, Shirley J., Gualberto G. Gonazlez-Sapienza, Bruce D. Hammock, Hee-Joo Kim, and Mark R. McCoy. 2011. Noncompetitive phage anti-immunocomplex real-time polymerase chain reaction for sensitive detection of small molecules. Analytical Chemistry.   83(1):246-253. doi:10.1021/ac102353z  
  • Honetschlagerova, Z., Z. Huskova, Z. Vanourkova, A. Sporkova, H. Kramer, Sung Hee Hwang, Hsing-Ju Tsai, Bruce D. Hammock, John D. Imig, L. Cervenka, and L. Kopkan. 2011. Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension. Journal of Physiology-London. 589:207-219. doi:10.1113/jphysiol.2010.199505  
  • Hwang, Sung Hee, Karen M. Wagner, Christophe Morisseau, Jun-Yan Liu, Hua Dong, Aaron T. Wecksler, and Bruce D. Hammock. 2011. Synthesis and Structure-Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase. Journal of Medicinal Chemistry.   54:3037-3050. doi:10.1021/jm2001376  
  • Inceoglu, Bora, Karen M. Wagner, Nils Helge Schebb, Christophe Morisseau, Steven L. Jinks, Arzu Ulu, Christine M. Hegedus, T. Rose, Christine Hegedus, and Bruce D. Hammock. 2011. Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   108:5093-5097. doi:10.1073/pnas.1101073108  
  • Inoue, Hiromi, Sung Hee Hwang, Aaron T. Wecksler, Bruce D. Hammock, and Robert H. Weiss. 2011. Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy. Cancer Biology & Therapy. 12:827-836. doi:10.4161/cbt.12.9.17680  
  • Kamita, Shizou G., Aman I. Samra, Jun-Yan Liu, Anthony J. Cornel, and Bruce D. Hammock. 2011. Juvenile Hormone (JH) Esterase of the Mosquito Culex quinquefasciatus Is Not a Target of the JH Analog Insecticide Methoprene. PLoS ONE.   6:doi:10.1371/journal.pone.0028392  
  • Kim, Young Ah, Eun-Hye Lee, Kwang-Ok Kim, Yong Tae Lee, Bruce D. Hammock, and Hye-Sung Lee. 2011. Competitive immunochromatographic assay for the detection of the organophosphorus pesticide chlorpyrifos. Analytica Chimica Acta.   693(1-2):106-113. doi:10.1016/j.aca.2011.03.011  
  • Koeners, Maarten P., Sebastiaan Wesseling, Arzu Ulu, Rocio Lopez Sepulveda, Christophe Morisseau, Branko Braam, Bruce D. Hammock, and Jaap A. Joles. 2011. Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats. American Journal of Physiology - Endocrinology and Metabolism.   300:E691-698. doi:10.1152/ajpendo.00710.2010  
  • Li, Yang Yang, Jun-Yan Liu, Todd R. Harris, Padmini Sirish, Bruce D. Hammock, and Nipavan Chiamvimonvat. 2011. Use of metabolomics profiling in the study of arachidonic acid metabolism in cardiovascular disease. American Journal of Cardiology.   17:42-46. doi:10.1111/j.1751-7133.2010.00209.x  
  • Liu, Jun-Yan, Hong Qiu, C. Moisseau, Sung Hee Hwang, Hsing-Jo Tsai, Arzu Ulu, Nipavan Chiamvimonvat, and Bruce D. Hammock. 2011. Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model. Toxicology and Applied Pharmacology.   255:200-206. doi:10.1016/j.taap.2011.06.017  
  • Luria, Ayala, Ahmed Bettaieb, Yannan Xi, Guang-Jong Shieh, Hsin-Chen Liu, Hiromi Inoue, Hsing-Ju Tsai, John D. Imig, Fawaz G. Haj, and Bruce D. Hammock. 2011. Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   108(22):9038-9043. doi:10.1073/pnas.1103482108  
  • Morisseau, Christophe, Maud Bernay, Aurélie Escaich, James R. Sanborn, Jozsef Lango, and Bruce D. Hammock. 2011. Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies. Analytical Biochemistry.   414:154-162. doi:10.1016/j.ab.2011.02.038  
  • Qiu, Hong, Ning Li, Jun-Yan Liu, Todd R. Harris, Bruce D. Hammock, and Nipavan Chiamvimonvat. 2011. Soluble Epoxide Hydrolase Inhibitors and Heart Failure. Cardiovascular Therapeutics. 29:99-111. doi:10.1111/j.1755-5922.2010.00150.x  
  • Schebb, Nils Helge, Marion Huby, Christophe Morisseau, Sung Hee Hwang, and Bruce D. Hammock. 2011. Development of an online SPE-LC-MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors. Analytical and Bioanalytical Chemistry.   400(5):1359-1366.
  • Schebb, Nils Helge, Bora Inceoglu, Ki Chang Ahn, Christophe Morisseau, Shirley J. Gee, and Bruce D. Hammock. 2011. Investigation of Human Exposure to Triclocarban after Showering and Preliminary Evaluation of Its Biological Effects. Environmental Science & Technology.   45:3109-3115. doi:10.1021/es103650m   (Completed with ARRA Funds)
  • Schebb, Nils Helge, Bora Inceoglu, Ki Chang Ahn, C. Morrisseau, Shirley J. Gee, and Bruce D. Hammock. 2011. Development of an online SPE-LC-MS-based assay using endogenous substrate for the investigation of soluble epoxide hydrolase (sEH) inhibitors. Anal. Bioanal. Chem. Analytical and Bioanalytical Chemistry.   400:1359-1366. doi:10.1007/s00216-011-4861-2  
  • Schebb, Nils Helge, Bora Inceoglu, Tristan E. Rose, Karen M. Wagner, and Bruce D. Hammock. 2011. Development of an ultra fast online-solid phase extraction (SPE) liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS/MS) based approach for the determination of drugs in pharmacokinetic studies. Analytical Methods.   3:420-428. doi:10.1039/c0ay00714e  
  • Schebb, Nils Helge, Tomofumi Kurobe, B. Franze, Anupama Ranganathan, Bruce D. Hammock, Swee J. Teh, and Ida Flores. 2011. Bioconcentration, metabolism and excretion of triclocarban in larval Qurt medaka (Oryzias latipes). Aquatic Toxicology.   105:448-454. doi:10.1016/j.aquatox.2011.07.020  
  • Sporkova, Alexandra, L. Kopkan, Sarka Varcabova, Zuzana Huskova, Sung Hee Hwang, Bruce D. Hammock, John D. Imig, Herbert J. Kramer, and Ludek Cervenka. 2011. Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology.   300:R1468-R1475. doi:10.1152/ajpregu.00215.2010  
  • Tabares-da Rosa, Sofia, Martin A. Rossotti, Carmen Carleiza, Federico Carrion, Otto Pritsch, Ki Chang Ahn, Jerold A. Last, Bruce D. Hammock, and Gualberto G. Gonzalez-Sapienza. 2011. Competitive Selection from Single Domain Antibody Libraries Allows Isolation of High-Affinity Antihapten Antibodies That Are Not Favored in the llama Immune Response. Analytical Chemistry.   83:7213-7220. doi:10.1021/ac201824z  
  • Wagner, Karen M., Bora Inceoglu, Sarjeet Gill, and Bruce D. Hammock. 2011. Epoxygenated Fatty Acids and Soluble Epoxide Hydrolase Inhibition: Novel Mediators of Pain Reduction. Journal of Agricultural and Food Chemistry.   59:2816-2824. doi:10.1021/jf102559q  
  • Wagner, Karen M., Bora Inceoglu, and Bruce D. Hammock. 2011. Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception. Prostaglandins & Other Lipid Mediators. 96:76-83. doi:10.1016/j.prostaglandins.2011.08.001  
  • Yang, Jiang-Hua, Hua Dong, and Bruce D. Hammock. 2011. Profiling the regulatory lipids: another systemic way to unveil the biological mystery. Current Opinion in Lipidology. 22:197-203. doi:10.1097/MOL.0b013e3283468c10  
  • Ye, Xiaoyun, Xiaoliu Zhou, Johnathan Furr, Ki Chang Ahn, Bruce D. Hammock, Earl L. Gray, and Antonia M. Calafat. 2011. Biomarkers of exposure to triclocarban in urine and serum. Toxicology.   286(1-30):69-74. doi:10.1016/j.tox.2011.05.008   (Completed with ARRA Funds)
  • Yin, Zhaohong, Victorina Pintea, Yanping Lin, Bruce D. Hammock, and Mitchell A. Watsky. 2011. Vitamin D enhances corneal epithelial barrier function. Investigative Ophthalmology & Visual Science.   52:7359-7364. doi:10.1167/iovs.11-7605  
2010
  • Alihosseini, Farzaneh, Jozsef Lango, Kou-San Ju, Bruce D. Hammock, and Gang Sun. 2010. Mutation of bacterium Vibrio gazogenes for selective preparation of colorants. Biotechnology Progress.   26(2):352-360. doi:10.1002/btpr.346  
  • Baumann, A., W. Lohmann, Tristan E. Rose, Ki Chang Ahn, Bruce D. Hammock, U. Karst, and Nils Helge Schebb. 2010. Electrochemistry-mass spectrometry unveils the formation of reactive triclocarban metabolites. Drug Metabolism and Disposition.   38(12):2130-2138. doi:10.1124/dmd.110.034546   (Completed with ARRA Funds)
  • Carlomagno, Mariana, Cecilia Matho, Guillermina Cantou, James R. Sanborn, Jerold A. Last, Bruce D. Hammock, Alvaro Roel, David Gonzalez, and Gualberto G. Gonzalez-Sapienza. 2010. A Clomazone Immunoassay To Study the Environmental Fate of the Herbicide in Rice (Oryza sativa) Agriculture. Journal of Agricultural and Food Chemistry.   58(7):4367-4371. doi:10.1021/jf9043259  
  • Chabova, Vera C., Agnieszka Walkowska, Elzbieta Kompanowska-Jezierska, Janusz Sadowski, Petr Kujal, Zdena Vernerova, Z. Vanourkova, L. Kopkan, H. Kramer, John D. Imig, Bruce D. Hammock, I. Vaneckova, L. Cervenka, and J.R. Falck. 2010. Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats. Clinical Science. 118:617-632. doi:10.1042/cs20090459  
  • Garcia-Nieto, E., Mikaela J. Nichkova, L. Yanez, R. Costilla-Salazar, A. Torres-Dosal, Shirley J. Gee, Bruce D. Hammock, L. Juarez-Santacruz, and F. Diaz-Barriga. 2010. Assessment of Dioxin-Like Soil Contamination in Mexico by Enzyme-Linked Immunosorbent Assay. Archives of Environmental Contamination and Toxicology.   58(4):918-926. doi:10.1007/s00244-009-9422-8  
  • Hall, Laura M., Michael Kimlin, Pavel A. Aronov, Bruce D. Hammock, James Slusser, Leslie Woodhouse, and Charles B. Stephensen. 2010. Vitamin D Intake Needed to Maintain Target Serum 25-Hydroxyvitamin D Concentrations in Participants with Low Sun Exposure and Dark Skin Pigmentation Is Substantially Higher Than Current Recommendations. Journal of Nutrition.   140(3):542-550. doi:10.3945/jn.109.115253  
  • Kim, Hee-Joo, Martin A. Rossotti, Ki Chang Ahn, Gualberto G. Gonzalez-Sapienza, Shirley J. Gee, Ruthie Musker, and Bruce D. Hammock. 2010. Development of a noncompetitive phage anti-immunocomplex assay for brominated diphenyl ether 47. Analytical Biochemistry.   401(1):38-46. doi:10.1016/j.ab.2010.01.040  
  • Kubala, Lukas, Kara R. Schmelzer, A. Klinke, H. Kolarova, S. Baldus, Bruce D. Hammock, and Jason P. Eiserich. 2010. Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. Free Radical Biology & Medicine,. Free Radical Biology and Medicine.   48(10):1311-1320. doi:10.1016/j.freeradbiomed.2010.02.010  
  • Liu, Jun-Yan, Ning Li, Jun Yang, Nan Li, Hong Qiu, Ding Ai, Nipavan Chiamvimonvat, Yi Zhu, and Bruce D. Hammock. 2010. Metabolic profiling of murine plasma reveals an unexpected biomarker in rofecoxib-mediated cardiovascular events. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   107(39):17017-17022. doi:10.1073/pnas.1011278107  
  • Morisseau, Christophe, Bora Inceoglu, Kara R. Schmelzer, Hsing-Ju Tsai, Steven L. Jinks, Christine M. Hegedus, and Bruce D. Hammock. 2010. Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids. Journal of Lipid Research.   51:3481-3490. doi:10.1194/jlr.M006007  
  • Nording, Malin L., Jun Yang, Christine M. Hegedus, A. Bhushan, N.J. Kenyon, C.E. Davis, and Bruce D. Hammock. 2010. Endogenous levels of five fatty acid metabolites in exhaled breath condensate to monitor asthma by high-performance liquid chromatography: Electrospray tandem mass spectrometry. IEEE Sensors Journal.   10(1):123-130. doi:10.1109/JSEN.2009.2035736  
  • Rayo, Josep, Lourdes Munoz, Gloria Rosell, Bruce D. Hammock, Angel Guerrero, F. Javier Luque, and Ramon Pouplana. 2010. Reactivity versus steric effects in fluorinated ketones as esterase inhibitors: a quantum mechanical and molecular dynamics study. Journal of Molecular Modeling.   16(11):1753-1764. doi:10.1007/s00894-010-0807-4  
  • Rose, T., Christophe Morisseau, Jun-Yan Liu, Bora Inceoglu, Paul D. Jones, James R. Sanborn, and Bruce D. Hammock. 2010. 1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure-Activity Relationships, Pharmacokinetics, and Reduction of Inflammatory Pain. Journal of Medicinal Chemistry.   53(19):7067-7075. doi:10.1021/jm100691c  
  • Rossotti, Martin A., Mariana Carlomagno, A. Gonzalez-Techera, Bruce D. Hammock, Jerold A. Last, and Gualberto G. Gonzalez-Sapienza. 2010. Phage anti-immunocomplex assay for clomazone: Two-site recognition increasing assay specificity and facilitating adaptation into an on-site format. Analytical Chemistry.   82(21):8838-8843. doi:10.1021/ac101476f  
  • Tsai, Hsing-Ju, Sung Hee Hwang, Christophe Morisseau, Jun Yang, Paul D. Jones, Takeo Kasagami, In-Hae Kim, and Bruce D. Hammock. 2010. Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs. European Journal of Pharmaceutical Sciences. 40(3):222-238. doi:10.1016/j.ejps.2010.03.018  
  • Wang, York, Arzu Ulu, L. Zhang, and Bruce D. Hammock. 2010. Soluble Epoxide Hydrolase in Atherosclerosis. Current Atherosclerosis Reports. 12:174-183. doi:10.1007/s11883-010-0108-5  
2009
  • Ahn, Ki Chang, Shirley J. Gee, Hsing-Ju Tsai, Deborah H. Bennett, Marcia Nishioka, Arlene Blum, Elana Fishman, and Bruce D. Hammock. 2009. Immunoassay for Monitoring Environmental and Human Exposure to the Polybrominated Diphenyl Ether BDE-47. Environmental Science & Technology.   43(20):7784-7790. doi:10.1021/es9009037  
  • Ai, Ding, Wei Pang, N. Li, Ming Xu, Paul D. Jones, J. Yang, Y. Zhang, Nipavan Chiamvimonvat, John Y-J Shyy, Bruce D. Hammock, and Yi Zhu. 2009. Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   106(2):564-569. doi:10.1073/pnas.0811022106  
  • Barbosa-Sicard, Eduardo, Timo Fromel, Benjamin Keseru, Ralf P. Brandes, Christophe Morisseau, Bruce D. Hammock, Thomas Braun, Marcus Kruger, and Ingrid Fleming. 2009. Inhibition of the Soluble Epoxide Hydrolase by Tyrosine Nitration. Journal of Biological Chemistry.   284:28156-28163. doi:10.1074/jbc.M109.054759  
  • Chawengsub, Yuttana, K.M. Gauthier, Kasem Nithipatikom, Bruce D. Hammock, John R. Falck, Dubasi Narsimhaswamy, and William B. Campbell. 2009. Identification of 13-Hydroxy-14,15-epoxyeicosatrienoic Acid as an Acid-stable Endothelium-derived Hyperpolarizing Factor in Rabbit Arteries. Journal of Biological Chemistry.   284:31280-31290. doi:10.1074/jbc.M109.025627  
  • Falck, J.R., Ravinder Kodela, Rajkumar Manne, Krishnam R. Atcha, Narender Puli, Narsimhaswamy Dubasi, Vijay L. Manthati, Jorge H. Capdevila, Xiu-Yu Yi, Daniel H. Goldman, Christophe Morisseau, Bruce D. Hammock, and William B. Campbell. 2009. 14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: Influence upon vascular relaxation and soluble epoxide hydrolase inhibition. Journal of Medicinal Chemistry.   52(16):5069. doi:10.1021/jm900634w  
  • Huang, Huazhang, Hiromasa Tanaka, Bruce D. Hammock, and Christophe Morisseau. 2009. Novel and highly sensitive fluorescent assay for leucine aminopeptidases. Analytical Biochemistry.   391(1):11-16. doi:10.1016/j.ab.2009.05.004  
  • Inceoglu, Ahmet B., Troy Waite, Julie A. Christiansen, R.D. McAbee, Shizou G. Kamita, Bruce D. Hammock, and Anthony J. Cornel. 2009. A rapid luminescent assay for measuring cytochrome P450 activity in individual larval Culex pipiens complex mosquitoes (Diptera: Culicidae). Journal of Medical Entomology. 46(1):83-92. doi:10.1603/033.046.0111  
  • Kasagami, Takeo, In-Hae Kim, Hsing-Ju Tsai, Kosuke Nishi, Bruce D. Hammock, and Christophe Morisseau. 2009. Salicylate-urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities. Bioorganic & Medicinal Chemistry Letters. 19(6):1784-1789. doi:10.1016/j.bmcl.2009.01.069  
  • Kim, H.J., Ki Chang Ahn, A. Gonzalez-Techera, Gualberto G. Gonzalez-Sapienza, Shirley J. Gee, and Bruce D. Hammock. 2009. Magnetic bead-based phage anti-immunocomplex assay (PHAIA) for the detection of the urinary biomarker 3-phenoxybenzoic acid to assess human exposure to pyrethroid insecticides. Analytical Biochemistry.   386(1):45-52. doi:10.1016/j.ab.2008.12.003  
  • Li, Ning, Jun-Yan Liu, Valeriy Timofeyev, Hong Qiu, Sung Hee Hwang, Dipika Tuteja, Ling Lu, Jun Yang, Hideki Mochida, Reginald Low, Bruce D. Hammock, and Nipavan Chiamvimonvat. 2009. Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches. Journal of Molecular & Cellular Cardiology. 47(6):835-845. doi:10.1016/j.yjmcc.2009.08.017  
  • Liu, Jun-Yan, See-Hyoung Park, Christophe Morisseau, Sung Hee Hwang, Bruce D. Hammock, and Robert H. Weiss. 2009. Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo. Molecular Cancer Therapeutics.   8(8):2193-2203. doi:10.1158/1535-7163.MCT-09-0119  
  • Liu, Jun-Yan, Hsing-Ju Tsai, Sung Hee Hwang, Paul D. Jones, Christophe Morisseau, and Bruce D. Hammock. 2009. Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation. British Journal of Pharmacology.   156(2):284-296. doi:10.1111/j.1476-5381.2008.00009.x  
  • Lu, Chunye, Robert Schoenfeld, Yuxi Shan, Hsing-Jo Tsai, Bruce D. Hammock, and Gino A. Cortopassi. 2009. Frataxin deficiency induces Schwann cell inflammation and death. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.   1792(11):1052-1061. doi:10.1016/j.bbadis.2009.07.011  
  • Luria, Ayala, Christophe Morisseau, Hsing-Ju Tsai, Jun Yang, Bora Inceoglu, Bart De Taeye, Michelle M. Wiest, J. Bruce German, Bruce D. Hammock, and Steven M. Watkins. 2009. Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase. American Journal of Physiology - Endocrinology and Metabolism.   297(2):E375-E383. doi:10.1152/ajpendo.00131.2009  
  • Ma, Zhiya, Dosi Dosev, Mikaela J. Nichkova, Randy K. Dumas, Shirley J. Gee, Bruce D. Hammock, and Ian M. Kennedy. 2009. Synthesis and characterization of multifunctional silica core-shell nanocomposites with magnetic and fluorescent functionalities. Journal of Magnetism and Magnetic Materials.   321(10):1368-1371. doi:10.1016/j.jmmm.2009.02.040  
  • Ma, Zhiya, Dosi Dosev, Mikaela J. Nichkova, Shirley J. Gee, Bruce D. Hammock, and Ian M. Kennedy. 2009. Synthesis and bio-functionalization of multifunctional magnetic Fe3O4@Y2O3:Eu nanocomposites. Journal of Materials Chemistry.   19:4695-4700. doi:10.1039/B901427F  
  • Matveeva, Evgenia G., Christophe Morisseau, Marvin H. Goodrow, Chris Mullin, and Bruce D. Hammock. 2009. Tryptophan fluorescence quenching by enzyme inhibitors as a tool for enzyme active site structure investigation: epoxide hydrolase. Current Pharmaceutical Biotechnology.   10(6):589-599. doi:10.2174/138920109789069260  
  • Morisseau, Christophe, Oleg Merzlikin, Amy Lin, G. He, Wei Feng, Isela Padilla, Michael S. Denison, Isaac N. Pessah, and Bruce D. Hammock. 2009. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environmental Health Perspectives. 117(12):1867-1872.
  • Nichkova, Mikaela J., Xun Fu, Zheng Yang, Ping Zhong, James R. Sanborn, Dan Chang, Shirley J. Gee, and Bruce D. Hammock. 2009. Immunochemical Screening of Pesticides (Simazine and Cypermethrin) in Orange Oil. Journal of Agricultural and Food Chemistry.   57(13):56735679. doi:10.1021/jf900652a  
  • Parrish, Alan R., Gang Chen, Robert C. Burghardt, Takaho Watanabe, Bruce D. Hammock, and Christophe Morisseau. 2009. Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase. Cell Biology and Toxicology. 25(3):217-225. doi:10.1007/s10565-008-9071-0  
  • Shen, Shuijie, Fan Zhang, Su Zeng, Ye Tian, Xiaojuan Chai, Shirley J. Gee, Bruce D. Hammock, and Jiang Zheng. 2009. Development of Enantioselective Polyclonal Antibodies to Detect Styrene Oxide Protein Adducts. Analytical Chemistry.   81(7):2668-2677. doi:10.1021/ac8023262  
  • Yang, Jun, Kara R. Schmelzer, Katrin Georgi, and Bruce D. Hammock. 2009. Quantitative Profiling Method for Oxylipin Metabolome by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry. Analytical Chemistry.   81(19):8085-8093. doi:10.1021/ac901282n  
2008
  • Aronov, Pavel A., Laura M. Hall, Katja Dettmer, Charles B. Stephensen, and Bruce D. Hammock. 2008. Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra-performance liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry.   391(5):1917-30. doi:10.1007/s00216-008-2095-8  
  • Aronova, Sofia, Karen Wedaman, Pavel A. Aronov, Kristin Fontes, Karmela Ramos, Bruce D. Hammock, and Ted Powers. 2008. Regulation of ceramide biosynthesis by TOR complex 2. Cell Metabolism. 7(2):148-158. doi:10.1016/j.cmet.2007.11.015  
  • Barbosa-Sicard, Eduardo, Rudiger Popp, Beate Fisslthaler, Bruce D. Hammock, John R. Falck, Rudi Busse, Ingrid Fleming, Benjamin Keseru, Alexander Dietrich, Thomas Gudermann, and Norbert Weissmann. 2008. Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response. FASEB Journal.   22(12):4306-15. doi:10.1096/fj.08-112821  
  • Bradbury, J.Alyce, Joan Graves, Laura M. Degraff, Xueying Zhao, John D. Imig, Theresa L. Pedersen, John W. Newman, Bruce D. Hammock, A.J. Conley, K.S. Korach, Darryl C. Zeldin, Krairerk Athirakul, Jixiang Ma, Yun Zhao, John F. Couse, Raymond Quigley, David R. Harder, and Thomas M. Coffman. 2008. Increased blood pressure in mice lacking cytochrome P450 2J5. FASEB Journal.   22(12):4096-108. doi:10.1096/fj.08-114413  
  • Chawengsub, Yuttana, N. Aggarwal, Kasem Nithipatikom, K.M. Gauthier, Siddam Anjaiah, Bruce D. Hammock, John R. Falck, and William B. Campbell. 2008. Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta. American Journal of Physiology - Heart and Circulatory Physiology.   294(3):1348-56.
  • Chen, Jiangang, Ki Chang Ahn, Nancy A. Gee, Mohamed I. Ahmed, Antoni J. Duleba, Ling Zhao, Shirley J. Gee, Bruce D. Hammock, and Bill L. Lasley. 2008. Triclocarban enhances testosterone action: a new type of endocrine disruptor?. Endocrinology.   149(3):1173-1179. doi:10.1210/en.2007-1057  
  • Chen, Jiangang, Ki Chang Ahn, Bin Zhao, Michael S. Denison, Bill L. Lasley, Isaac N. Pessah, Dietmar Kultz, Daniel PY Chang, Shirley J. Gee, Bruce D. Hammock, and Gennady Cherednichenko. 2008. In Vitro Biologic Activities of the Antimicrobials Triclocarban, Its Analogs, and Triclosan in Bioassay Screens: Receptor-Based Bioassay Screens. Environmental Health Perspectives. 116:1203-1210. doi:10.1289/ehp.11200  
  • Corenblum, Mandi J., Vance E. Wise, Katrin Georgi, Bruce D. Hammock, Peter A. Doris, and Myriam Fornage. 2008. Altered soluble epoxide hydrolase gene expression and function and vascular disease risk in the stroke-prone spontaneously hypertensive rat. Hypertension.   51(2):567-73.
  • Dreisbach, A.W., J.C. Rice, S. Japa, John W. Newman, A. Sigel, R. Gill, A.E. Hess, A.C. Cemo, J.P. Fonseca, Bruce D. Hammock, J.J. Lertora, and L.L. Hamm. 2008. Salt loading increases urinary excretion of linoleic acid diols and triols in healthy human subjects. Hypertension.   51:755-761.
  • Enayetallah, Ahmed E., Ayala Luria, Beibei Luo, Hsing-Ju Tsai, Priyanks Sura, Bruce D. Hammock, and David F. Grant. 2008. Opposite regulation of cholesterol levels by the phosphatase and hydrolase domains of soluble epoxide hydrolase. Journal of Biological Chemistry.   283:36592-8. doi:10.1074/jbc.M806315200  
  • Fife, Kimberly L., YingMei Liu, Kara R. Schmelzer, Hsing-Ju Tsai, In-Hae Kim, Christophe Morisseau, Bruce D. Hammock, and Deanna L. Kroetz. 2008. Inhibition of Soluble Epoxide Hydrolase Does Not Protect against Endotoxin-Mediated Hepatic Inflammation. Journal of Pharmacology and Experimental Therapeutics.   327:707-715. doi:10.1124/jpet.108.142398  
  • Gonzalez-Techera, A., M. Umpierrez-Failache, S. Cardozo, G. Obal, Jerold A. Last, Shirley J. Gee, Bruce D. Hammock, Gualberto G. Gonzalez-Sapienza, and O. Pritsch. 2008. High-throughput method for ranking the affinity of peptide ligands selected from phage display libraries. Bioconjugate Chemistry.   19(5):993-1000. doi:10.1021/bc700279y  
  • Gross, Garrett J., K.M. Gauthier, Jeannine Moore, John R. Falck, Bruce D. Hammock, William B. Campbell, and Kasem Nithipatikom. 2008. Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. American Journal of Physiology - Heart and Circulatory Physiology.   294(6):H2838-44. doi:10.1152/ajpheart.00186.2008  
  • Harris, Todd R., Pavel A. Aronov, and Bruce D. Hammock. 2008. Soluble epoxide hydrolase homologs in Strongylocentrotus purpuratus suggest a gene duplication event and subsequent divergence. DNA and Cell Biology.   27(9):467-77. doi:10.1089/dna.2008.0751  
  • Hwang, Hyun-Min, Eun-Kee Park, Thomas M. Young, and Bruce D. Hammock. 2008. Occurrence of endocrine-disrupting chemicals in indoor dust. Science of the Total Environment.   404(1):26-35. doi:10.1016/j.scitotenv.2008.05.031  
  • Inceoglu, Bora, Steven L. Jinks, Arzu Ulu, Christine M. Hegedus, Katrin Georgi, Kara R. Schmelzer, Karen M. Wagner, Paul D. Jones, Christophe Morisseau, and Bruce D. Hammock. 2008. Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   105(48):18901-18906. doi:10.1073/pnas.0809765105  
  • Jiang, H., Angela G. Zhu, Magdalena Mamczur, Christophe Morisseau, Bruce D. Hammock, John R. Falck, and John C. McGiff. 2008. Hydrolysis of cis- and trans-epoxyeicosatrienoic acids by rat red blood cells. Journal of Pharmacology and Experimental Therapeutics.   326(1):330-7. doi:10.1124/jpet.107.134858  
  • Kim, H.J., A. Gonzalez-Techera, Gualberto G. Gonzalez-Sapienza, Ki Chang Ahn, Shirley J. Gee, and Bruce D. Hammock. 2008. Phage-borne peptidomimetics accelerate the development of polyclonal antibody-based heterologous immunoassays for the detection of pesticide metabolites. Environmental Science & Technology.   42(6):2047-53. doi:10.1021/es702219a  
  • Morisseau, Christophe and Bruce D. Hammock. 2008. Gerry Brooks and epoxide hydrolases: four decades to a pharmaceutical. Pest Management Science. 64(6):594-609. doi:10.1002/ps.1583  
  • Morisseau, Christophe, John W. Newman, Craig E. Wheelock, Thomas Hill, Dexter Morin, Alan R. Buckpitt, and Bruce D. Hammock. 2008. Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase. Chemical Research in Toxicology.   21(4):951-7. doi:10.1021/tx700446u  
  • Park, Eun-Kee, Hector Duarte Tagles, Shirley J. Gee, Bruce D. Hammock, K. Lee, and Marc B. Schenker. 2008. Recruiting strategy and 24-hour biomonitoring of paraquat in agricultural workers. Journal of Agromedicine. 13(4):207-17.
  • Pedersen, Theresa L., R.J. Grekin, Bruce D. Hammock, D.L. Ball, and A. Vollmer. 2008. Heparin, lipoproteins, and oxygenated fatty acids in blood: a cautionary note. Prostaglandins, Leukotrienes and Essential Fatty Acids. 77(5-6):363-366. doi:10.1016/j.plefa.2007.10.012  
  • Tanaka, Hiromasa, Shizou G. Kamita, Nicola M. Wolf, Todd R. Harris, Zaining Wu, Christophe Morisseau, and Bruce D. Hammock. 2008. Transcriptional regulation of the human soluble expoxide hydrolase gene EPHX2. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms.   1779(1):17-27. doi:10.1016/j.bbagrm.2007.11.005  
  • Van Emon, Jeanette M., Jane Chuang, Robert A. Lordo, Mary E. Schrock, Mikaela J. Nichkova, Shirley J. Gee, and Bruce D. Hammock. 2008. An enzyme-linked immunosorbent assay for the determination of dioxins in contaminated sediment and soil samples. Chemosphere.   72(1):95-103. doi:10.1016/j.chemosphere.2008.01.012  
  • Wheelock, Craig E., J. Forshed, S. Goto, Bruce D. Hammock, and John W. Newman. 2008. Effects of Pyridine Exposure upon Structural Lipid Metabolism in Swiss Webster Mice. Chemical Research in Toxicology.   21(3):583-90. doi:10.1021/tx7002454  
  • Wheelock, Craig E., Kosuke Nishi, Paul D. Jones, Michael E. Colvin, Marilyn M. Olmstead, and Bruce D. Hammock. 2008. Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH). Bioorganic & Medicinal Chemistry.   16(4):2114-30. doi:10.1016/j.bmc.2007.10.081  
  • Wheelock, Craig E., Bryn M. Phillips, Jeff L. Miller, Marion G. Miller, and Bruce D. Hammock. 2008. Applications of carboxylesterase activity in environmental monitoring and Toxicity Identification Evaluations (TIEs). Reviews of Environmental Contamination and Toxicology.   195:doi:10.1007/978-0-387-77030-7  
2007
  • Ahn, Ki Chang, Pete N. Lohstroh, Shirley J. Gee, Nancy A. Gee, Bill L. Lasley, and Bruce D. Hammock. 2007. High-throughput automated luminescent magnetic particle-based immunoassay to monitor human exposure to pyrethroid insecticides. Analytical Chemistry.   79(b):8883-90.
  • Ai, Ding, Yi Fu, Deliang Guo, Hiromasa Tanaka, Nanping Wang, Chaoshu Tang, Bruce D. Hammock, John Y-J Shyy, and Yi Zhu. 2007. Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   104(21):9018-23.
  • Akatsuka, Toshitaka, Takashi Ishikawa, Nobuharu Kobayashi, Takafumi Saito, Michiko Shindo, Masayoshi Yamauchi, Kazutaka Kurokohchi, Hitoshi Miyazawa, Hongying Duan, Toshiyuki Matsunaga, Tsugikazu Komoda, Christophe Morisseau, and Bruce D. Hammock. 2007. Autoantibody response to microsomal epoxide hydrolase in hepatitis C and A. Journal of Autoimmunity. 28(1):7-18. doi:10.1016/j.jaut.2006.12.005  
  • Chen, Jiangang, Ki Chang Ahn, Shirley J. Gee, Nancy A. Gee, Bruce D. Hammock, and Bill L. Lasley. 2007. Antiandrogenic properties of parabens and other phenolic containing small molecules in personal care products. Toxicology and Applied Pharmacology.   221(a):278-284.
  • Chiamvimonvat, Nipavan, C-M Ho, Hsing-Ju Tsai, and Bruce D. Hammock. 2007. The soluble epoxide hydrolase as a pharmaceutical target for hypertension. Journal of Cardiovascular Pharmacology. 50:225-237.
  • Chiappe, Cinzia, Elsa Leandri, Bruce D. Hammock, and Christophe Morisseau. 2007. Effect of ionic liquids on epoxide hydrolase-catalyzed synthesis of chiral 1,2-diols. Green Chemistry.   9:162-168. doi:10.1039/B612106C  
  • Dettmer, Katja, Pavel A. Aronov, and Bruce D. Hammock. 2007. Mass spectrometry-based metabolomics. Mass Spectrometry Reviews.   26(1):51-78.
  • Dettmer, Katja, D. Hanna, Paul Whetstone, R. Hansen, and Bruce D. Hammock. 2007. Autism and urinary exogenous neuropeptides: development of an on-line SPE-HPLC-tandem mass spectrometry method to test the opioid excess theory. Analytical and Bioanalytical Chemistry.   388:1643-1651.
  • Devonshire, A.L., R. Heidari, Huazhang Huang, Bruce D. Hammock, Robyn J. Russell, and John G. Oakeshott. 2007. Hydrolysis of individual isomers of fluorogenic pyrethroid analogs by mutant carboxylesterases from Lucilia cuprina. Insect Biochemistry and Molecular Biology. 37:891-902.
  • Dosev, Dosi, Mikaela J. Nichkova, Randy K. Dumas, Shirley J. Gee, Bruce D. Hammock, Kai Liu, and Ian M. Kennedy. 2007. Magnetic/luminescent core/shell particles synthesized by spray pyrolysis and their application in immunoassays with internal standard. Nanotechnology.   18(5):055102(6pp).
  • Endsley, Michael P., N. Aggarwal, Margaret A. Isbell, Craig E. Wheelock, Bruce D. Hammock, J.R. Flack, William B. Campbell, and Kasem Nithipatikom. 2007. Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: location, hydrolysis and 12-lipoxygenase metabolism. International Journal of Cancer.   121:984-991.
  • Fleming, Ingrid, Alexandria Rueben, Rudiger Popp, Beate Fisslthaler, Anna Sander, Judith Haendeler, John R. Falck, Christophe Morisseau, Bruce D. Hammock, and Rudi Busse. 2007. Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells. Arteriosclerosis, Thrombosis and Vascular Biology.   27(12):2612-8.
  • Gonzalez-Techera, A., H.J. Kim, Shirley J. Gee, Jerold A. Last, and Bruce D. Hammock. 2007. Polyclonal Antibody-Based Noncompetitive Immunoassay for Small Analytes Developed with Short Peptide Loops Isolated from Phage Libraries. Analytical Chemistry.   79:9191-9196. doi:10.1021/ac7016713  
  • Gonzalez-Techera, A., L. Vanrell, Jerold A. Last, Bruce D. Hammock, and Gualberto G. Gonzalez-Sapienza. 2007. Phage anti-immune complex assay: general strategy for noncompetitive immunodetection of small molecules. Analytical Chemistry.   79(20):7799-806. doi:10.1021/ac071323h  
  • Hillard, C.J., W.S. Ho, J. Thompson, K.M. Gauthier, Craig E. Wheelock, Huazhang Huang, and Bruce D. Hammock. 2007. Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. British Journal of Pharmacology.   152(5):691-8.
  • Huang, Huazhang, Kosuke Nishi, Hsing-Ju Tsai, and Bruce D. Hammock. 2007. Development of highly sensitive fluorescent assays for fatty acid amide hydrolase. Analytical Biochemistry.   363(1):12-21.
  • Hwang, Sung Hee, Hsing-Ju Tsai, Jennifer Liu, Christophe Morisseau, and Bruce D. Hammock. 2007. Orally bioavailable potent soluble epoxide hydrolase inhibitors. Journal of Medicinal Chemistry.   50:3825-3840.
  • Inceoglu, Bora, Kara R. Schmelzer, Christophe Morisseau, Steven L. Jinks, and Bruce D. Hammock. 2007. Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs). Prostaglandins & Other Lipid Mediators. 82(1-4):42-49.
  • Kim, H.J., Ki Chang Ahn, Seung Jin Ma, Shirley J. Gee, and Bruce D. Hammock. 2007. Development of sensitive immunoassays for the detection of the glucuronide conjugate of 3-phenoxybenzyl alcohol, a putative human urinary biomarker for pyrethroid exposure. Journal of Agricultural and Food Chemistry.   55(10):3750-7.
  • Kim, Hee-Joo, Shirley J. Gee, Qing X. Li, and Bruce D. Hammock. 2007. Noncompetitive Fluorescent Immunoassay for the Detection of the Human Urinary Biomarker 3-Phenoxybenzoic Acid with Bench Top Immunosensor KinExATM 3000. Chapter 11in: Rational Environmental Management of Agrochemicals: Risk Assessment, Monitoring, and Remedial Action. pp.171185.
  • Kim, In-Hae, Kosuke Nishi, Hsing-Ju Tsai, Tanya Bradford, Yasuko Koda, Takaho Watanabe, Christophe Morisseau, Joanne Blanchfield, Istvan Toth, and Bruce D. Hammock. 2007. Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry.   15(1):312-23.
  • Kim, In-Hae, Hsing-Ju Tsai, Kosuke Nishi, Takeo Kasagami, Christophe Morisseau, and Bruce D. Hammock. 2007. 1,3-Disubstituted ureas functionalized with ether groups and potent inhibitors of the soluble epoxide hydrolase with improved pharmacokinetic properties. Journal of Medicinal Chemistry.   50:5217-5226.
  • Loch, D., A. Hoey, Christophe Morisseau, Bruce D. Hammock, and L. Brown. 2007. Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble epoxide hydrolase. Cell Biochemistry and Biophysics. 47:87-97.
  • Luria, Ayala, Steven M. Weldon, A.K. Kabcenell, R.H. Ingraham, D. Matera, H. Jiang, R. Gill, Christophe Morisseau, John W. Newman, and Bruce D. Hammock. 2007. Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice. Journal of Biological Chemistry.   282(5):2891-8.
  • Newman, John W., George A. Kaysen, Bruce D. Hammock, and Gregory C. Shearer. 2007. Proteinuria increases oxylipid concentrations in VLDL and HDL, but not LDL particles in the rat. Journal of Lipid Research.   48:1792-1800.
  • Nichkova, Mikaela J., Dosi Dosev, Alexander E. Davies, Shirley J. Gee, Ian M. Kennedy, and Bruce D. Hammock. 2007. Multiplexed immunoassays for biomonitoring of exposure to agrochemicals using quantum dots as fluorescent reporters. Proceedings of SPIE. 6448:644817-1. doi:10.1117/12.699231  
  • Nichkova, Mikaela J., Dosi Dosev, Alexander E. Davies, Shirley J. Gee, Ian M. Kennedy, and Bruce D. Hammock. 2007. Quantum dots as reporters in multiplexed immunoassays for biomarkers of exposure to agrochemicals. Analytical Letters. 40(7):1423-1433. doi:10.1080/00032710701327088  
  • Nichkova, Mikaela J., Dosi Dosev, Shirley J. Gee, Bruce D. Hammock, and Ian M. Kennedy. 2007. Multiplexed immunoassays for proteins using magnetic luminescent nanoparticles for internal calibration. Analytical Biochemistry.   369(a):34-40.
  • Park, Eun-Kee, Sally K. Mak, Bruce D. Hammock, and Dietmar Kultz. 2007. Evaluation of cytotoxicity attributed to thimerosal on murine and human kidney cells. Journal of Toxicology and Environmental Health, Part A.   70(24):2092-5.
  • Park, Eun-Kee, Sally K. Mak, Dietmar Kultz, and Bruce D. Hammock. 2007. Determination of cytotoxicity of nephrotoxins on murine and human kidney cell lines. Journal of Environmental Science and Health, Part B.   43:71-74.
  • Thompson, David A. and Bruce D. Hammock. 2007. Dihydroxyoctadecamonoenoate esters inhibit the neutrophil respiratory burst. Journal of Biosciences. 32(2):279-91.
  • Wadkins, Randy M., Janice L. Hyatt, Carol C. Edwards, Lyudmila Tsurkan, Matthew R. Redinbo, Craig E. Wheelock, Paul D. Jones, Bruce D. Hammock, and Philip M. Potter. 2007. Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds. Molecular Pharmacology.   71(3):713-723.
  • Wheelock, Craig E., S. Goto, Bruce D. Hammock, and John W. Newman. 2007. Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics.   3:137-145.
  • Yuan, W., Joyce S. Chung, Shirley J. Gee, Bruce D. Hammock, and Jiang Zheng. 2007. Development of polyclonal antibodies for detection of styrene oxide modified proteins. Chemical Research in Toxicology.   20:316-321.
  • Zhang, Wenri, Ines P. Koerner, Ruediger Noppens, Marjorie Grafe, Hsing-Ju Tsai, Christophe Morisseau, Ayala Luria, Bruce D. Hammock, John R. Falck, and Nabil J. Alkayed. 2007. Soluble epoxide hydrolase: a novel therapeutic target in stroke. Journal of Cerebral Blood Flow & Metabolism. 27(12):1931-40.
2006
  • Ahn, Ki Chang, Seung Jin Ma, Hsing-Ju Tsai, Shirley J. Gee, and Bruce D. Hammock. 2006. An immunoassay for a urinary metabolite as a biomarker of human exposure to the pyrethroid insecticide permethrin. Analytical and Bioanalytical Chemistry.   384(3):713-722.
  • Carkeet, Colleen, Stephen R. Dueker, Jozsef Lango, Bruce A. Buchholz, Joshua W. Miller, Ralph Green, Bruce D. Hammock, John R. Roth, and Peter J. Anderson. 2006. Human vitamin B12 absorption measurement by accelerator mass spectrometry using specifically labeled 14C-cobalamin. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   103(15):5694-5699.
  • Cummins, C.M., Marja E. Koivunen, Ara Stephanian, Shirley J. Gee, Bruce D. Hammock, and Ian M. Kennedy. 2006. Application of europium(III) chelate-dyed nanoparticle labels in a competitive atrazine fluoroimmunoassay on an ITO waveguide. Biosensors & Bioelectronics.   21(7):1077-1085.
  • Davis, Benjamin B., Christophe Morisseau, John W. Newman, Theresa L. Pedersen, Bruce D. Hammock, and Robert H. Weiss. 2006. Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition. Journal of Pharmacology and Experimental Therapeutics.   316(2):815-821.
  • Gomez, German A., Christophe Morisseau, Bruce D. Hammock, and David W. Christianson. 2006. Human soluble epoxide hydrolase: Structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids. Protein Science.   15(1):58-64.
  • Harris, Todd R., Christophe Morisseau, Rosemary L. Walzem, Seung Jin Ma, and Bruce D. Hammock. 2006. The cloning and characterization of a soluble epoxide hydrolase in chicken. Poultry Science.   82(2):278-287.
  • Huang, Huazhang, Kosuke Nishi, Shirley J. Gee, and Bruce D. Hammock. 2006. Evaluation of chiral -cyanoesters as general fluorescent substrates for screening enantioselective esterases. Journal of Agricultural and Food Chemistry.   54(3):694-699.
  • Hwang, Sung Hee, Christophe Morisseau, Zung N. Do, and Bruce D. Hammock. 2006. Solid-phase combinatorial approach for the optimization of soluble epoxide hydrolase inhibitors. Bioorganic & Medicinal Chemistry Letters. 16(22):5773-7.
  • Inceoglu, Bora, Steven L. Jinks, Kara R. Schmelzer, Troy Waite, In-Hae Kim, and Bruce D. Hammock. 2006. Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain. Life Sciences.   79(24):2311-2319.
  • Inceoglu, Bora, Jozsef Lango, Paul Whetstone, and Bruce D. Hammock. 2006. The neutralizing effect of a polyclonal antibody raised against the N-terminal eighteen-aminoacid residues of birtoxin towards the whole venom of Parabuthus transvaalicus. Toxicology.   47(2):144-149.
  • Jones, Paul D., Hsing-Ju Tsai, Zung N. Do, Christophe Morisseau, and Bruce D. Hammock. 2006. Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase. Bioorganic & Medicinal Chemistry Letters. 16(19):5212-5216.
  • Koivunen, Marja E., Katja Dettmer, Roel Vermeulen, Berit Bakke, Shirley J. Gee, and Bruce D. Hammock. 2006. Improved methods for urinary atrazine mercapturate analysisAssessment of an enzyme-linked immunosorbent assay (ELISA) and a novel liquid chromatographymass spectrometry (LCMS) method utilizing online solid phase extraction (SPE). Analytica Chimica Acta.   572(2):180-189.
  • Larsen, Brandon T., Hiroto Miura, Ossama A. Hatoum, William B. Campbell, Bruce D. Hammock, Darryl C. Zeldin, John R. Falck, and David D. Gutterman. 2006. Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BKCa channels: implications for soluble epoxide hydrolase inhibition. American Journal of Pathology.   290(2):H491-H499.
  • Lee, Craig R., Kari E. North, Molly S. Bray, Myriam Fornage, John M. Seubert, John W. Newman, Bruce D. Hammock, David J. Couper, Gerardo Heiss, and Darryl C. Zeldin. 2006. Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. Human Molecular Genetics.   15(10):1640-1649.
  • Morisseau, Christophe, John W. Newman, Hsing-Ju Tsai, Preston A. Baecker, and Bruce D. Hammock. 2006. Peptidyl-urea based inhibitors of soluble epoxide hydrolases. Bioorganic & Medicinal Chemistry Letters. 16(20):5439-5444.
  • Ng, Valerie Y., Christophe Morisseau, John R. Falck, Bruce D. Hammock, and Deanna L. Kroetz. 2006. Inhibition of Smooth Muscle Proliferation by Urea-Based Alkanoic Acids via Peroxisome Proliferator-Activated Receptor {alpha}Dependent Repression of Cyclin D1. Arteriosclerosis, Thrombosis and Vascular Biology.   26(11):4262.
  • Nichkova, Mikaela J., Dosi Dosev, Richard Perron, Shirley J. Gee, Bruce D. Hammock, and Ian M. Kennedy. 2006. Eu3+-doped Gd2O3 nanoparticles as reporters for optical detection and visualization of antibodies patterned by microcontact printing. Analytical and Bioanalytical Chemistry.   384(3):631-637.
  • Nishi, Kosuke, Huazhang Huang, Shizou G. Kamita, In-Hae Kim, Christophe Morisseau, and Bruce D. Hammock. 2006. Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2. Archives of Biochemistry and Biophysics.   445(1):115-123.
  • Nording, Malin, Mikaela J. Nichkova, Erik Spinnel, Ylva Persson, Shirley J. Gee, Bruce D. Hammock, and Peter Haglund. 2006. Rapid screening of dioxin-contaminated soil by accelerated solvent extraction/purification followed by immunochemical detection. Analytical and Bioanalytical Chemistry.   385(2):357-366.
  • Olearczyk, Jeffery J., Mary B. Field, In-Hae Kim, Christophe Morisseau, Bruce D. Hammock, and John D. Imig. 2006. Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels. Journal of Pharmacology and Experimental Therapeutics.   318(3):1307-1314.
  • Pokreisz, Peter, Ingrid Fleming, Ladislau Kiss, Eduardo Barbosa-Sicard, Beate Fisslthaler, John R. Falck, Bruce D. Hammock, In-Hae Kim, Zsolt Szelid, Pieter Vermeersch, Hilde Gillijns, Marijke Pellens, Friedrich Grimminger, Anton-Jan van Zonneveld, Desire Collen, Rudi Busse, and Stefan Janssens. 2006. Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling. Hypertension.   47(4):762-770.
  • Schmelzer, Kara R., Bora Inceoglu, Lukas Kubala, In-Hae Kim, Steven L. Jinks, Jason P. Eiserich, and Bruce D. Hammock. 2006. Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   103(37):13646-13651.
  • Schmelzer, Kara R., Asa M. Wheelock, Katja Dettmer, Dexter Morin, and Bruce D. Hammock. 2006. The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways. Environmental Health Perspectives. 114(9):1354-1360.
  • Seubert, John M., Christopher J. Sinal, Joan Graves, Laura M. Degraff, J. Alyce Bradbury, Craig R. Lee, Kerry Goralski, Michelle A. Carey, Ayala Luria, John W. Newman, Bruce D. Hammock, John R. Falck, Holly Roberts, Howard A. Rockman, Elizabeth Murphy, and Darryl C. Zeldin. 2006. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circulation Research.   99(4):442-450.
  • Watanabe, Takaho, Daniel Schulz, Christophe Morisseau, and Bruce D. Hammock. 2006. High-throughput pharmacokinetic method: Cassette dosing in mice. Analytica Chimica Acta.   559(1):37-44.
  • Wheelock, Asa M., Jeff L. Miller, Mike J. Miller, Bryn M. Phillips, Sarah A. Huntley, Shirley J. Gee, Ronald S. Tjeerdema, and Bruce D. Hammock. 2006. Use of carboxylesterase activity to remove pyrethroid-associated toxicity to Ceriodaphnia dubia and Hyalella azteca in toxicity identification evaluations. Environmental Toxicology and Chemistry.   25(4):973-984.
  • Wolf, Nicola M., Christophe Morisseau, Paul D. Jones, Bertold Hock, and Bruce D. Hammock. 2006. Development of a high-throughput screen for soluble epoxide hydrolase inhibition. Analytical Biochemistry.   355(1):71-80.
  • Xu, Danyan, Ning Li, Yuxia He, Valeriy Timofeyev, Ling Lu, Hsing-Ju Tsai, In-Hae Kim, Dipika Tuteja, Robertino Karlo P. Mateo, Anil Singapuri, Benjamin B. Davis, Reginald Low, Bruce D. Hammock, and Nipavan Chiamvimonvat. 2006. Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   103(49):18733-18738.
  • Zhao, Bin, David S. Baston, Bruce D. Hammock, and Michael S. Denison. 2006. Interaction of diuron and related substituted phenylureas with the Ah receptor pathway. Journal of Biochemical and Molecular Toxicology.   20(3):103-113.
2005
  • Ahn, Ki Chang, Shirley J. Gee, H.J. Kim, Mikaela J. Nichkova, and Bruce D. Hammock. 2005. Progress in the development of biosensors for environmental and human monitoring of agrochemicals. Proceedings of the American Chemical Society Pacifichem. 966:138-154.
  • Aronov, Pavel A., Katja Dettmer, Julie A. Christiansen, Anthony J. Cornel, and Bruce D. Hammock. 2005. Development of a HPLC/tandem-MS method for the analysis of the larvicides methoprene, hydroprene and kinoprene at trace levels using Diels-Alder derivatization. Journal of Agricultural and Food Chemistry.   53(9):3306-3312.
  • Dorrance, Ann M., Nicole Rupp, David M. Pollock, John W. Newman, Bruce D. Hammock, and John D. Imig. 2005. An epoxide hydrolase inhibitor, 12-(3-Adamantan-1-yl-ureido)dodecanoic acid (AUDA) reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. Journal of Cardiovascular Pharmacology. 46(6):842-848.
  • Dosev, Dosi, Mikaela J. Nichkova, Maozi Liu, Bing Guo, Gang-yu Liu, Bruce D. Hammock, and Ian M. Kennedy. 2005. Application of luminescent Eu:Gd2O3 nanoparticles to the visualization of protein micropatterns. Journal of Biomedical Optics. 10(6):1-7.
  • Dosev, Dosi, Mikaela J. Nichkova, Maozi Liu, Bing Guo, Gang-yu Liu, Younan Xia, Bruce D. Hammock, and Ian M. Kennedy. 2005. Application of fluorescent Eu:Gd2O3 nanoparticles to the visualization of protein micropatterns. Chapter 5699 in: Imaging, Manipulation, and Analysis of Biomolecules and Cells: Fundamentals and Applications: III (Proceedings of SPIE). SPIE Society of Photo-Optical Instrumentation Engineering, San Jose, CA. pp.473-481.
  • Fang, Xianx, Shanming Hu, Takaho Watanabe, Neal L. Weintraub, Gary D. Snyder, Jianrong Yao, Yi Liu, John Y-J Shyy, Bruce D. Hammock, and Author A. Spector. 2005. Activation of Peroxisome Proliferator-Activated Receptor by Substituted Urea-Derived Soluble Epoxide Hydrolase Inhibitors. Journal of Pharmacology and Experimental Therapeutics.   314(1):260-270.
  • German, J.Bruce, Bruce D. Hammock, and Steven M. Watkins. 2005. Metabolomics: building on a century of biochemistry to guide human health. Metabolomics.   1(1):3-9.
  • Hennebold, Jon D., Kuni Mah, Wilma Perez, Jessica E. Vance, Richard L. Stouffer, Christophe Morisseau, Bruce D. Hammock, and Eli Y. Adashi. 2005. Identification and characterization of an ovary-selective isoform of epoxide hydrolase. Biology of Reproduction.   72(4):968-975.
  • Huang, Huazhang, Christopher D. Fleming, Kosuke Nishi, Matthew R. Redinbo, and Bruce D. Hammock. 2005. Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases. Chemical Research in Toxicology.   18(9):1371-1377.
  • Huang, Huazhang, Jeanette E. Stok, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock. 2005. Development of optically pure pyrethroid-like fluorescent substrates for carboxylesterases. Chemical Research in Toxicology.   18(3):516-527.
  • Imig, John D., Xueying Zhao, Constantine Z. Zaharis, Jeffery J. Olearczyk, David M. Pollock, John W. Newman, In-Hae Kim, Takaho Watanabe, and Bruce D. Hammock. 2005. An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension.   46(4):975-981.
  • Inceoglu, Bora, Jozsef Lango, Isaac N. Pessah, and Bruce D. Hammock. 2005. Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity. Toxicon.   45(6):727-733.
  • Jones, Paul D., Nicola M. Wolf, Christophe Morisseau, Paul Whetstone, Bertold Hock, and Bruce D. Hammock. 2005. Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies. Analytical Biochemistry.   343(1):66-75.
  • Jung, Oliver, Ralf P. Brandes, In-Hae Kim, Frank Schweda, Ronald Schmidt, Bruce D. Hammock, Rudi Busse, and Ingrid Fleming. 2005. Soluble epoxide hydrolase is a main effector of angiotensin ll-induced hypertension. Hypertension.   45(4):759-765.
  • Kang, Kyung-Don, Paul D. Jones, Huazhang Huang, Rong Zhang, Lyudmila A. Mostovich, Craig E. Wheelock, Takaho Watanabe, Lyudmila F. Gulyaeva, and Bruce D. Hammock. 2005. Evaluation of a-cyano ethers as fluorescent substrates for assay of cytochrome P450 enyzme activity. Analytical Biochemistry.   344(2):183-192.
  • Kim, In-Hae, Fenton R. Heirtzler, Christophe Morisseau, Kosuke Nishi, Hsing-Ju Tsai, and Bruce D. Hammock. 2005. Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. Journal of Medicinal Chemistry.   48(10):3621-3629.
  • Koivunen, Marja E., Shirley J. Gee, Eun-Kee Park, K. Lee, Marc B. Schenker, and Bruce D. Hammock. 2005. Application of an enzyme-linked immunosorbent assay for the analysis of paraquat in human exposure samples. Archives of Environmental Contamination and Toxicology.   48(2):184-190.
  • Liu, Yi, Yingjia Zhang, Kara R. Schmelzer, Tzong-Shyuan Lee, Xianx Fang, Yi Zhu, Author A. Spector, Sarjeet Gill, Christophe Morisseau, Bruce D. Hammock, and John Y-J Shyy. 2005. The antiinflammatory effect of laminar flow: The role of PPAR, epoxyeicosatrienoic acids, and soluble epoxide hydrolase. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   102(46):16747-16752.
  • Mak, Sally K., Guomin Shan, Hu-Jang Lee, Takaho Watanabe, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock. 2005. Development of a class selective immunoassay for the type II pyrethroid insecticides. Analytica Chimica Acta.   534:109-120.
  • Morisseau, Christophe and Bruce D. Hammock. 2005. Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles. Annual Review of Pharmacology and Toxicology.   45:311-333.
  • Newman, John W., Christophe Morisseau, and Bruce D. Hammock. 2005. Epoxide hydrolases: their roles and interactions with lipid metabolism. Progress in Lipid Research. 44(1):1-50.
  • Nichkova, Mikaela J., Dosi Dosev, Shirley J. Gee, Bruce D. Hammock, and Ian M. Kennedy. 2005. Microarray of immunoassay for phenoxybenzoic acid using polymer encapsulated Eu:Gd2O3 nanoparticles as fluorescent labels. Analytical Chemistry.   77(21):6864-6873.
  • Nithipatikom, Kasem, Michael P. Endsley, Marilyn A. Isbell, Craig E. Wheelock, Bruce D. Hammock, and William B. Campbell. 2005. A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. Biochemical and Biophysical Research Communications.   332(4):1028-1033.
  • Schmelzer, Kara R., Lukas Kubala, John W. Newman, In-Hae Kim, Jason P. Eiserich, and Bruce D. Hammock. 2005. Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   102(28):9772-9777.
  • Sellers, Kathleen W., Chengwen Sun, Carlos Diez-Freire, Hidefumi Waki, Christophe Morisseau, John R. Falck, Bruce D. Hammock, Julian F. Paton, and Mohan K. Raizada. 2005. Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat. FASEB Journal.   19:626-628.
  • Shearer, Gregory C., John W. Newman, Bruce D. Hammock, and George A. Kaysen. 2005. Graded effects of proteinuria on HDL structure in nephrotic rats. Journal of the American Society of Nephrology. 16(5):1309-1319.
  • Smith, Kevin R., Kent E. Pinkerton, Takaho Watanabe, Theresa L. Pedersen, Seung Jin Ma, and Bruce D. Hammock. 2005. Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   102(6):2186-2191.
  • Tran, Katherine L., Pavel A. Aronov, Hiromasa Tanaka, John W. Newman, Bruce D. Hammock, and Christophe Morisseau. 2005. Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase. Biochemistry.   44(36):12179-12187.
  • Wheelock, Craig E., Kai J. Eder, Ingeborg Werner, Huazhang Huang, Paul D. Jones, Benjamin F. Brammell, Adria A. Elskus, and Bruce D. Hammock. 2005. Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos. Aquatic Toxicology.   74(2):172-192.
  • Wheelock, Craig E., Jeff L. Miller, Mike J. Miller, Bryn M. Phillips, Shirley J. Gee, Ronald S. Tjeerdema, and Bruce D. Hammock. 2005. Influence of container adsorption upon observed pyrethroid toxicity to Ceriodaphnia dubia and Hyalella azteca. Aquatic Toxicology.   74(1):47-52.
2004
  • Ahn, Ki Chang, Takaho Watanabe, Shirley J. Gee, and Bruce D. Hammock. 2004. Hapten and antibody production for a sensitive immunoassay determinining a human urinary metabolite of the pyrethroid insecticide permethrin. Journal of Agricultural and Food Chemistry.   52(15):4583-4594.
  • Denison, Michael S., W.J. Rogers, Jessica E. Bohonowych, Bin Zhao, Aparajita Dey, Roger S. Williams, David M. Pollock, David W. Stepp, John W. Newman, Bruce D. Hammock, and John D. Imig. 2004. Promiscuous ligand-dependent activation of the Ah receptor: chemicals in crude extracts from commercial and consumer products bind to and activate the Ah receptor and Ah receptor-dependent gene expression. Organohalogen Compounds. 66:2966-2971.
  • Dey, Aparajita, Roger S. Williams, David M. Pollock, David W. Stepp, John W. Newman, Bruce D. Hammock, and John D. Imig. 2004. Altered Kidney CYP2C and Cyclooxygenase-2 Levels Are Associated with Obesity-Related Albuminuria. Obesity.   12(8):1278-1289. doi:10.1038/oby.2004.162  
  • DuTeaux, Shelley Brown, John W. Newman, Christophe Morisseau, Elise A. Fairbairn, Karen Jelks, Bruce D. Hammock, and Marion G. Miller. 2004. Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism. Toxicological Sciences.   78(2):187-195.
  • Fang, Xianx, Neal L. Weintraub, Ryan B. McCaw, Shanming Hu, Shawn Harmon, James B. Rice, Bruce D. Hammock, and Author A. Spector. 2004. Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels. American Journal of Physiology - Cell Physiology.   287:H2412-H2420.
  • Gomez, German A., Christophe Morisseau, Bruce D. Hammock, and David W. Christianson. 2004. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochemistry.   43(16):4716-4723.
  • Kennedy, Ian M., Marja E. Koivunen, Shirley J. Gee, C.M. Cummins, Richard Perron, Dosi Dosev, and Bruce D. Hammock. 2004. Nanoscale fluoro-immuno assays with lanthanide oxide nanoparticles. Chapter 5593 in: Nanosensing: Materials and Devices (Proceedings of SPIE). SPIE Society of Photo-Optical Instrumentation Engineering, Bellingham, WA. pp.329-339.
  • Kim, In-Hae, Christophe Morisseau, Takaho Watanabe, and Bruce D. Hammock. 2004. Design, Synthesis, and Biological Activity of 1,3-Disubstituted Ureas as Potent Inhibitors of the Soluble Epoxide Hydrolase of Increased Water Solubility. Journal of Medicinal Chemistry.   47(8):759-765.
  • Lee, Hu-Jang, Guomin Shan, Ki Chang Ahn, Eun-Kee Park, Takaho Watanabe, Shirley J. Gee, and Bruce D. Hammock. 2004. Development of an enzyme-linked Immunosorbent assay for the pyrethroid cypermethrin. Journal of Agricultural and Food Chemistry.   52(2):1039-1043.
  • Newman, John W., Jeanette E. Stok, J.D. Vidal, C.J. Corbin, Qihung Huang, Bruce D. Hammock, and A.J. Conley. 2004. Cytochrome P450-dependent lipid metabolism in preovulatory follicles. Endocrinology.   145(11):5097-5105.
  • Nichkova, Mikaela J., Eun-Kee Park, Marja E. Koivunen, Shizou G. Kamita, Shirley J. Gee, Jane Chuang, Jeanette M. Van Emon, and Bruce D. Hammock. 2004. Immunochemical determination of dioxins in environmental and biological samples. Talanta.   63:1213-1223.
  • Park, Eun-Kee, Jung-Hyun Kim, Shirley J. Gee, Takaho Watanabe, Ki Chang Ahn, and Bruce D. Hammock. 2004. Determination of pyrethroid residues in agricultural products by an enzyme-linked immunosorbent assay. Journal of Agricultural and Food Chemistry.   52(18):5572-5576.
  • Rufo, Caterina, Bruce D. Hammock, Shirley J. Gee, Jerold A. Last, and Gualberto G. Gonzalez-Sapienza. 2004. Robust and sensitive monoclonal enzyme-linked immunosorbent assay for the herbicide molinate. Journal of Agricultural and Food Chemistry.   52(2):182-187.
  • Seubert, John M., Baichun Yang, J. Alyce Bradbury, Joan Graves, Laura M. Degraff, Scott Gabel, Rebecca Gooch, Julie Foley, John W. Newman, Lan Mao, Howard A. Rockman, Bruce D. Hammock, Elizabeth Murphy, and Darryl C. Zeldin. 2004. Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K+ Channels and p42/p44 MAPK Pathway. Circulation Research.   95(5):506-514.
  • Shan, Guomin, Huazhang Huang, Donald W. Stoutamire, Shirley J. Gee, Gabriele Leng, and Bruce D. Hammock. 2004. A sensitive class specific immunoassay for the detection of pyrethroid metabolites in human urine. Chemical Research in Toxicology.   17(2):218-225.
  • Stok, Jeanette E., Andrey Goloshchapov, Cheng Song, Craig E. Wheelock, Maher Derbel, Christophe Morisseau, and Bruce D. Hammock. 2004. Investigation of the role of a second conserved serine in carboxylesterases via site-directed mutagenesis. Archives of Biochemistry and Biophysics.   430(2):247-255.
  • Stok, Jeanette E., Huazhang Huang, Paul D. Jones, Craig E. Wheelock, Christophe Morisseau, and Bruce D. Hammock. 2004. Identification, expression and purification of a pyrethroid hydrolyzing carboxylesterase from mouse liver microsomes. Journal of Biological Chemistry.   279(28):29863-29869.
  • Wheelock, Craig E., Jeff L. Miller, Mike J. Miller, Shirley J. Gee, Guomin Shan, and Bruce D. Hammock. 2004. Development of toxicity identification evaluation procedures for pyrethroid detection using esterase activity. Environmental Toxicology and Chemistry.   23(11):2699-2708.
  • Yu, Zhigang, Benjamin B. Davis, Christophe Morisseau, Bruce D. Hammock, Jean L. Olson, Deanna L. Kroetz, and Robert H. Weiss. 2004. Vascular localization of soluble epoxide hydrolase in the human kidney. American Journal of Physiology - Renal Physiology.   286(4):F720-F726.
  • Zhao, Xueying, Tatsuo Yamamoto, John W. Newman, In-Hae Kim, Takaho Watanabe, Bruce D. Hammock, Janet Stewart, and John D. Imig. 2004. Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. Journal of the American Society of Nephrology. 15(5):1244-53.
2003
  • Chen, Shi-Che, P. Yuen, S. Collins, Robert Smith, Marja E. Koivunen, and Bruce D. Hammock. 2003. Time gated detection of europium nanoparticles in a microchannel-based environmental immunoassay. In: Proceedings of SPIE (The International Society for Optical Engineering).
  • Cho, Young Ae, Yoo Jung Kim, Bruce D. Hammock, Yong Tae Lee, and Hye-Sung Lee. 2003. Development of a microtiter plate ELISA and a dipstick ELISA for the determination of the organophosphorus insecticide fenthion. Journal of Agricultural and Food Chemistry.   51(27):7854-7860.
  • Denton, Debra L., Craig E. Wheelock, Shauna A. Murray, Linda A. Deanovic, Bruce D. Hammock, and David E. Hinton. 2003. Joint acute toxicity of esfenvalerate and diazinon to fathead minnow (Pimephales promelas) larvae. Environmental Toxicology and Chemistry.   22(2):336-341.
  • Feng, Jun, J.S. Mack, Guomin Shan, and Bruce D. Hammock. 2003. C60 nanoparticle quenching used as a biological label. In: Proceedings of SPIE (The International Society for Optical Engineering). pp.156-163.
  • Feng, Jun, Guomin Shan, Bruce D. Hammock, and Ian M. Kennedy. 2003. Fluorescence quenching competitive immunoassay in micro droplets. Biosensors & Bioelectronics.   18(8):1055-1063.
  • Feng, Jun, Guomin Shan, Angel Maquieira, Marja E. Koivunen, Bing Guo, and Bruce D. Hammock. 2003. Functionalized Europium Oxide Nanoparticles Used as a Fluorescent Label in an Immunoassay for Atrazine. Analytical Chemistry.   75(19):5282-5286.
  • Inceoglu, Bora, Jozsef Lango, Jie Jing, Lili Chen, Fuat Doymaz, Isaac N. Pessah, and Bruce D. Hammock. 2003. One scorpion, two venoms: Prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   100(3):922-927.
  • Kim, Yoo Jung, Young Ae Cho, Hye-Sung Lee, Yong Tae Lee, Shirley J. Gee, and Bruce D. Hammock. 2003. Synthesis of haptens for immunoassay of organophosphorus pesticides and effect of heterology in hapten spacer arm length of immunoassay sensitivity. Analytica Chimica Acta.   475(1-2):85-96.
  • Koivunen, Marja E., Christophe Morisseau, John W. Newman, William R. Horwath, and Bruce D. Hammock. 2003. Purification and characterization of a methylene urea-hydrolyzing enzyme from Rhizobium radiobacter (Agrobacterium tumefaciens). Soil Biology and Biochemistry.   35(11):1433-1442.
  • Lee, Hu-Jang, Takaho Watanabe, Shirley J. Gee, and Bruce D. Hammock. 2003. Application of an Enzyme-Linked Immunosorbent Assay (ELISA) to Determine Deltamethrin Residues in Milk. Bulletin of Environmental Contamination and Toxicology.   71(1):14-20.
  • Lee, Jae Koo, Ki Chang Ahn, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock. 2003. Development of an Enzyme-Linked Immunosorbent Assay for the Detection of the Organophosphorus Insecticide Acephate. Journal of Agricultural and Food Chemistry.   51(13):3695-3703.
  • McElroy, Nathan R., Peter C. Jurs, Christophe Morisseau, and Bruce D. Hammock. 2003. QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds. Journal of Medicinal Chemistry.   46(6):1066-1080.
  • Morisseau, Christophe and Bruce D. Hammock. 2003. Measurements of soluble epoxide hydrolase (sEH) activity. Chapter 4 in: Current Protocals in Toxicology. John Wiley & Sons, NY. pp.1-4.
  • Newman, John W., Christophe Morisseau, Todd R. Harris, and Bruce D. Hammock. 2003. The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   100(4):1558-1563.
  • Nichkova, Mikaela J., Jun Feng, Francisco Sanchez-Baeza, Maria-Pilar Marco, Bruce D. Hammock, and Ian M. Kennedy. 2003. Competitive quenching fluorescence immunoassy for chlorophenols based on laser-induced fluorescence detection in microdroplets. Analytical Chemistry.   75(1):83-90.
  • Przybyla-Zawislak, Beata D., Punit K. Srivastava, Johana Vazquez-Matias, Harvey W. Mohrenweiser, Joseph E. Maxwell, Bruce D. Hammock, J. Alyce Bradbury, Ahmed E. Enayetallah, Darryl C. Zeldin, and David F. Grant. 2003. Polymorphisms in human soluble epoxide hydrolase. Molecular Pharmacology.   64(2):482-490.
  • Szekacs, Andras, Hong M. Le, Ferenc Szurdoki, and Bruce D. Hammock. 2003. Optimization and validation of an enzyme immunoassay for the insect growth regulator fenoxycarb. Analytica Chimica Acta.   487(1):15-29.
  • Taniai, Kiyoko, Ahmet B. Inceoglu, Kenji Yukuhiro, and Bruce D. Hammock. 2003. Characterization and cDNA cloning of a clofibrate-inducible microsomal epoxide hydrolase in Drosophila melanogaster. FEBS Journal. 270(23):4696-4705.
  • Viswanathan, Saraswathi, Bruce D. Hammock, John W. Newman, Purushothaman Meerarani, Michal Toborek, and Bernhard Hennig. 2003. Involvement of CYP 2C9 in Mediating the Proinflammatory Effects of Linoleic Acid in Vascular Endothelial Cells. Journal of the American College of Nutrition.   22(6):502-510.
  • Watanabe, Takaho, Christophe Morisseau, John W. Newman, and Bruce D. Hammock. 2003. In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecy1-urea. Drug Metabolism and Disposition.   31(7):846-853.
  • Wheelock, Craig E., Yoshiaki Nakagawa, Miki Akamatsu, and Bruce D. Hammock. 2003. Use of classical and 3-D QSAR to examine the hydration state of juvenile hormone esterase inhibitors. Bioorganic & Medicinal Chemistry.   11(23):5101-5116.
  • Wheelock, Craig E., Asa M. Wheelock, Rebecca H. Zhang, Jeanette E. Stok, Christophe Morisseau, Susanna E. Le Valley, Carol E. Green, and Bruce D. Hammock. 2003. Evaluation of alpha-cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes. Analytical Biochemistry.   315(2):208-222.
  • Zhang, Rebecca H., Kyung-Don Kang, Guomin Shan, and Bruce D. Hammock. 2003. Design, synthesis and evaluation of novel P450 fluorescent probes bearing -cyanoether. Tetrahedron Letters.   44(23):4331-4334.
2002
  • Cho, Young Ae, Hye-Sung Lee, Eun Young Park, Yong Tae Lee, Bruce D. Hammock, Ki Chang Ahn, and Jae Koo Lee. 2002. Development of an ELISA for the organophosphorus insecticide chlorpyrifos. Bulletin of the Korean Chemical Society. 23(3):481-487.
  • Davis, Benjamin B., David A. Thompson, Laura L. Howard, Christophe Morisseau, Bruce D. Hammock, and Robert H. Weiss. 2002. Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   99(4):2222-2227.
  • Dedos, S.G., Ferenc Szurdoki, Andras Szekacs, T. Shiotsuki, Bruce D. Hammock, J. Shimada, and H. Fugo. 2002. Fenoxycarb levels and their effects on general and juvenile hormone esterase activity in the hemolymph of the silkworm, Bombyx mori. Pesticide Biochemistry and Physiology. 73(3):174-187.
  • Denison, Michael S., Scott R. Nagy, Michael H. Ziccardi, George C. Clark, Michael D. Chu, David J. Brown, Guomin Shan, Yukio Sugawara, Shirley J. Gee, James R. Sanborn, and Bruce D. Hammock. 2002. Bioanalytical approaches for the detection of dioxin and related halogenated aromatic hydrocarbons. In: Biomarkers of Environmentally Associated Disease: Technologies, Concepts, and Perspectives   . CRC Press Company, Boca Raton, FL. pp.483-494.
  • Fang, Xianx, Neal L. Weintraub, Christine L. Oltman, Lynn L. Stoll, Terry L. Kaduce, Shawn Harmon, Kevin C. Dellsperger, Christophe Morisseau, Bruce D. Hammock, and Author A. Spector. 2002. Human coronary endothelial cells convert 14, 15-EET to a biologically active chain-shortened epoxide. American Journal of Physiology - Heart and Circulatory Physiology.   283(6):H2306-H2314.
  • Feng, Jun, Guomin Shan, Bruce D. Hammock, and Ian M. Kennedy. 2002. Fluorescence quenching competitive fluoroimmunoassay in micro droplets. In: Methods for Ultrasensitive Detection II, Proceedings of the International Society for Optical Engineering. SPIE, Bellingham, WA. pp.118-127.
  • Fornage, Myriam, Cruz A. Hinojos, Barbara W. Nurowska, Eric Boerwinkle, Bruce D. Hammock, Christophe Morisseau, and Peter A. Doris. 2002. Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats. Hypertension.   40(4):485-490.
  • Harcourt, Rebecca L., Irene Horne, Tara D. Sutherland, Bruce D. Hammock, Robyn J. Russell, and John G. Oakeshott. 2002. Development of a simple and sensitive fluorimetric method for isolation or coumaphos-hydrolysing bacteria. Letters in Applied Microbiology.   34(4):263-268.
  • Hennig, Bernhard, Bruce D. Hammock, Rabih M. Slim, Michal Toborek, Saraswathi Viswanathan, and Larry W. Robertson. 2002. PCB-induced oxidative stress in endothelial cells: modulation by nutrients. International Journal of Hygiene and Environmental Health.   205(1-2):95-102.
  • Imig, John D., Xueying Zhao, Jorge H. Capdevila, Christophe Morisseau, and Bruce D. Hammock. 2002. Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension. Hypertension.   39(2):690-694.
  • Inceoglu, Bora, Yuki Hayashida, Jozsef Lango, Andrew T. Ishida, and Bruce D. Hammock. 2002. A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus. FEBS Journal. 269(22):5369-5376.
  • Kim, Kwang-Ok, Yoo Jung Kim, Yong Tae Lee, Bruce D. Hammock, and Hye-Sung Lee. 2002. Development of an enzyme-linked immunosorbent assay for the organophosphorus insecticide bromophos-ethyl. Journal of Agricultural and Food Chemistry.   50(23):6675-6682.
  • Lee, Hu-Jang, Guomin Shan, Takaho Watanabe, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock. 2002. Enzyme-linked immunosorbent assay for the pyrethroid deltamethrin. Journal of Agricultural and Food Chemistry.   50(20):5526-5532.
  • Leppert, Valerie J., Ashley S. Harvey, Geoff D. McCool, Forest T. Quinlan, Jun Feng, Guomin Shan, Pieter Stroeve, Subhash H. Risbud, Bruce D. Hammock, and Ian M. Kennedy. 2002. Long-wavelength emitting nanocrystals for bioassay applications. In: Nanoscale Optics and Applications. Proceedings of SPIE, pp.110-121.
  • Morisseau, Christophe and Bruce D. Hammock. 2002. Epoxide Hydrolases. In: Wiley Encyclopedia of Molecular Medicine. Medicine John Wiley & Sons Inc., New York, NY. pp.1194-1197.
  • Morisseau, Christophe, Marvin H. Goodrow, John W. Newman, Craig E. Wheelock, Deanna L. Dowdy, and Bruce D. Hammock. 2002. Structural refinement of inhibitors of urea based soluble epoxide hydrolases. Biochemical Pharmacology.   63(9):1599-1608.
  • Nagy, Scott R., James R. Sanborn, Bruce D. Hammock, and Michael S. Denison. 2002. Development of a green fluorescent protein based cell bioassay for the rapid and inexpensive detection and characterization of AhR agonists. Toxicological Sciences.   65(2):200-210.
  • Newman, John W., Takaho Watanabe, and Bruce D. Hammock. 2002. The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS. Journal of Lipid Research.   43(9):1563-1578.
  • Park, Won Chul, Young Ae Cho, Yoo Jung Kim, Bruce D. Hammock, Yong Tae Lee, and Hye-Sung Lee. 2002. Development of an enzyme-linked immunosorbent assay for the organophosphorus insecticide bromophos. Bulletin of the Korean Chemical Society. 23(10):1399-1403.
  • Severson, Tonya, Marvin H. Goodrow, Christophe Morisseau, Deanna L. Dowdy, and Bruce D. Hammock. 2002. Urea and amide-based inhibitors of the juvenile hormone epoxide hydrolase of the tobacco hornworm(Manduca sexta: Sphingidae). Insect Biochemistry and Molecular Biology. 32:1741-1756.
  • Shelver, Weilin L., Guomin Shan, Shirley J. Gee, Larry H. Stanker, and Bruce D. Hammock. 2002. Comparison of immunoaffinity column recovery patterns of polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans on columns generated with different monoclonal antibody clones and polyclonal antibodies. Analytica Chimica Acta.   457:199-209.
  • Sugawara, Yukio, Koichi Saito, Masahiko Ogawa, Susumu Kobayashi, Guomin Shan, James R. Sanborn, Bruce D. Hammock, Hiroyuki Nakazawa, and Yasuhiko Matsuki. 2002. Development of dioxin toxicity evaluation method in human milk by enzyme-linked immunosorbent assay--assay validation for human milk. Chemosphere.   46(9-10):1471-1476.
  • Szurdoki, Ferenc, Andras Szekacs, Hong M. Le, and Bruce D. Hammock. 2002. Synthesis of haptens and protein conjugates for the development of immunoassays for the insect growth regulator fenoxycarb. Journal of Agricultural and Food Chemistry.   50(1):29-40.
  • Viswanathan, Saraswathi, Bruce D. Hammock, Purushothaman Meerarani, Michal Toborek, and Bernhard Hennig. 2002. Mechanisms of linoleic acid-induced endothelial activation: possible involvement of epoxide metabolites in mediating the inflammatory response. FASEB Journal.   16:A157.
  • Wheelock, Craig E., Michael E. Colvin, Ippei Uemura, Marilyn M. Olmstead, James R. Sanborn, Yoshiaki Nakagawa, A. Daniel Jones, and Bruce D. Hammock. 2002. Use of ab initio calculations to predict the biological potency of carboxylesterase inhibitors. Journal of Medicinal Chemistry.   45(25):5576-5593.
  • Zurek, Gabriela, Shirley J. Gee, and Bruce D. Hammock. 2002. Development of an enzyme immunoassay for linoleic acid diols in urine. Analytica Chimica Acta.   466(2):247-256.
2001
  • Buchholz, Bruce A., John S. Vogel, Douglas S. Gilman, Shirley J. Gee, Bruce D. Hammock, Xiaoying Hui, Ronald C. Wester, and Howard I. Maibach. 2001. Determining an occupational dermal exposure biomarker for atrazine through measurement of metabolites in human urine by HPLC-accelerator mass spectrometry. In: Toxicology of Skin. Taylor & Francis, Philadelphia, PA. pp.145-157.
  • Fang, Xianx, Terry L. Kaduce, Neal L. Weintraub, Shawn Harmon, Lynn M. Teesch, Christophe Morisseau, David A. Thompson, Bruce D. Hammock, and Author A. Spector. 2001. Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells: Implications for the vascular effects of soluble epoxide hydrolase inhibition. Journal of Biological Chemistry.   276(18):14867-14874.
  • Hennig, Bernhard, Rabih M. Slim, Michal Toborek, Bruce D. Hammock, and Larry W. Robertson. 2001. Cardiovascular disease: endothelial cells as a target for PCB toxicity. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.211-220.
  • Hennig, Bernhard, Saraswathi Viswanathan, Michal Toborek, and Bruce D. Hammock. 2001. Mechanisms of fatty-acid mediated endothelial cell activation. Journal of the American College of Nutrition.   20:574.
  • Huang, Qihung, Quinn L. Deveraux, Shin Maeda, Henning R. Stennicke, Bruce D. Hammock, and John C. Reed. 2001. Cloning and characterization of an inhibitor of apoptosis protein (IAP) from Bombyx mori. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research.   1499(3):191-198.
  • Inceoglu, Bora, Jozsef Lango, Jennifer Wu, Pauline Hawkins, James Southern, and Bruce D. Hammock. 2001. Isolation and characterization of a novel type of neurotoxic peptide from the venom of the South African scorpion Parabuthus transvaalicus (Buthidae). FEBS Journal. 268(20):5407-5413.
  • Lee, Jae Koo, Ki Chang Ahn, Oee Suk Park, Shin Young Kang, and Bruce D. Hammock. 2001. Development of an ELISA for the detection of the residues of the insecticide imidacloprid in agricultural and environmental samples. Journal of Agricultural and Food Chemistry.   49(5):2159-2167.
  • Matveeva, Evgenia G., Elena V. Gribkova, James R. Sanborn, Shirley J. Gee, Bruce D. Hammock, and Alexander P. Savitsky. 2001. Development of a homogeneous phosphorescent immunoassay for the detection of polychlorinated dibenzo-p-dioxins. Analytical Letters. 34(13):2311-2320.
  • Matveeva, Evgenia G., Guomin Shan, Ian M. Kennedy, Shirley J. Gee, and Bruce D. Hammock. 2001. Homogeneous fluoroimmunoassay of a pyrethroid metabolite in urine. Analytica Chimica Acta.   444:103-117.
  • Miyashita, Masahiro, Jack M. Presley, Bruce A. Buchholz, Kit S. Lam, Young Moo Lee, John S. Vogel, and Bruce D. Hammock. 2001. Attomole level protein sequencing by Edman degradation coupled with accelerator mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   98(8):4403-4408.
  • Morisseau, Christophe, John W. Newman, Deanna L. Dowdy, Marvin H. Goodrow, and Bruce D. Hammock. 2001. Inhibition of microsomal epoxide hydrolases by ureas, amides and amines. Chemical Research in Toxicology.   14(4):409-415.
  • Newman, John W. and Bruce D. Hammock. 2001. Optimized thiol derivatizing reagent for the mass spectral analysis of disubstituted epoxy fatty acids. Journal of Chromatography A.   925(1-2):223-240.
  • Newman, John W., Debra L. Denton, Christophe Morisseau, Cory S. Koger, Craig E. Wheelock, David E. Hinton, and Bruce D. Hammock. 2001. Evaluation of fish models of soluble epoxide hydrolase inhibition. Environmental Health Perspectives. 109(1):61-66.
  • Shan, Guomin and Bruce D. Hammock. 2001. Development of sensitive esterase assays based on alpha-cyano-containing esters. Analytical Biochemistry.   299(1):54-62.
  • Shan, Guomin, Whitney R. Leeman, Shirley J. Gee, James R. Sanborn, A. Daniel Jones, Daniel PY Chang, and Bruce D. Hammock. 2001. Highly sensitive dioxin immunoassay and its application to soil and biota samples. Analytica Chimica Acta.   444:169-178.
  • Sisemore, Marlene F., Jiang Zheng, Joy C. Yang, David A. Thompson, Charles G. Plopper, Gino A. Cortopassi, and Bruce D. Hammock. 2001. Cellular characterization of leukotoxin diol-induced mitochondrial dysfunction. Archives of Biochemistry and Biophysics.   392(1):32-37.
  • Slim, Rabih M., Bruce D. Hammock, Michal Toborek, and Larry W. Robertson. 2001. The role of methyl linoleic acid epoxide and diol metabolites in the synergistic toxicity of linoleic acid and PCBs to vascular endothelial cells. Toxicological Sciences.   60:13.
  • Slim, Rabih M., Bruce D. Hammock, Michal Toborek, Larry W. Robertson, John W. Newman, Christophe Morisseau, Bruce A. Watkins, Saraswathi Viswanathan, and Bernhard Hennig. 2001. The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells. Toxicology and Applied Pharmacology.   171(3):184-193.
  • Staimer, Norbert, Shirley J. Gee, and Bruce D. Hammock. 2001. Development of a class-selective enzyme immunoassay for urinary phenolic glucuronides. Analytica Chimica Acta.   444:27-36.
  • Staimer, Norbert, Shirley J. Gee, and Bruce D. Hammock. 2001. Development of a sensitive enzyme immunoassay for the detection of phenyl-b-D-thioglucuronide in human urine. Fresenius' Journal of Analytical Chemistry.   369(3-4):273-279.
  • Viswanathan, Saraswathi, P. Narayan, Bruce D. Hammock, Purushothaman Meerarani, Michal Toborek, and Bernhard Hennig. 2001. Linoleic acid-derived epoxides alter calcium and nitric oxide metabolism in endothelial cells. FASEB Journal.   15:A190.
  • Watanabe, Takaho and Bruce D. Hammock. 2001. Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high performance liquid chromatography with electrospray tandem mass spectrometry. Analytical Biochemistry.   299(2):227-234.
  • Watanabe, Takaho, Guomin Shan, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock. 2001. Development of a class-specific immunoassay for the type I pyrethroid insecticides. Analytica Chimica Acta.   444:119-129.
  • Watkins, Steven M., Bruce D. Hammock, John W. Newman, and J. Bruce German. 2001. Individual metabolism should guide agriculture toward foods for improved health and nutrition. American Journal of Clinical Nutrition.   74(3):283-286.
  • Wheelock, Craig E., Tonya Severson, and Bruce D. Hammock. 2001. Synthesis of new carboxylesterase inhibitors and evaluation of potency and water solubility. Chemical Research in Toxicology.   14(12):1563-1572.
  • Wudayagiri, Rajendra, Bora Inceoglu, Rafael Herrmann, Maher Derbel, Prabahakara Choudary, and Bruce D. Hammock. 2001. Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus. BMC Biochemistry.   2:16.
  • Zheng, Jiang, Charles G. Plopper, Jeffery Lakritz, David H. Storms, and Bruce D. Hammock. 2001. Leukotoxin-diol - A putative toxic mediator involved in acute respiratory distress syndrome. American Journal of Respiratory Cell and Molecular Biology.   25(4):434-438.
2000
  • Argiriadi, Maria A., Christophe Morisseau, Marvin H. Goodrow, Deanna L. Dowdy, Bruce D. Hammock, and David W. Christianson. 2000. Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation. Journal of Biological Chemistry.   275(20):15265-15270.
  • Draper, Alison J. and Bruce D. Hammock. 2000. Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase. Archives of Biochemistry and Biophysics.   376(1):199-205.
  • Fanucchi, Michelle V., Alan R. Buckpitt, M. Murphy, David H. Storms, Bruce D. Hammock, and Charles G. Plopper. 2000. Development of phase II xenobiotic metabolizing enzymes in differentiating murine Clara cells. Toxicology and Applied Pharmacology.   168(3):253-267.
  • Greene, Jessica F., John W. Newman, Kenneth Williamson, and Bruce D. Hammock. 2000. Toxicity of epoxy fatty acids and related compounds to cells expressing human soluble epoxide hydrolase. Chemical Research in Toxicology.   13(4):217-226.
  • Greene, Jessica F., Kenneth Williamson, John W. Newman, Christophe Morisseau, and Bruce D. Hammock. 2000. Metabolism of monoepoxides of methyl linoleate: bioactivation and detoxification. Archives of Biochemistry and Biophysics.   376(2):420-432.
  • Greene, Jessica F., Jiang Zheng, David F. Grant, and Bruce D. Hammock. 2000. Cytotoxicity of 1,2-epoxynaphthalene is correlated with protein binding and in situ glutathione depletion in cytochrome P4501A1 expressing Sf-21 cells. Toxicological Sciences.   53(2):352-360.
  • Huang, Qihung, Quinn L. Deveraux, Susumu Maeda, Guy S. Salvesen, Henning R. Stennicke, Bruce D. Hammock, and John C. Reed. 2000. Evolutionary conservation of apoptosis mechanisms: Lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   97:1427-1432.
  • Kido, Horacio, Angel Maquieira, and Bruce D. Hammock. 2000. Disc-based immunoassay microarrays. Analytica Chimica Acta.   411(1-2):1-11.
  • Lakritz, Jeffery, Bruce S. Winder, Jaffar Noorouz-Zadeh, Tien L. Huang, Alan R. Buckpitt, Bruce D. Hammock, and Charles G. Plopper. 2000. Hepatic and pulmonary enzyme activities in horses. American Journal of Veterinary Research.   61(2):152-157.
  • Lohse, Christian, Lynn L. Jaeger, Norbert Staimer, James R. Sanborn, A. Daniel Jones, Jozsef Lango, Shirley J. Gee, and Bruce D. Hammock. 2000. Development of a class selective enzyme-linked immunosorbent assay for mercapturic acids in human urine. Journal of Agricultural and Food Chemistry.   48(12):5913-5923.
  • Morisseau, Christophe, Jeffrey K. Beetham, Frank Pinot, Stephane Debernard, John W. Newman, and Bruce D. Hammock. 2000. Cress and potato soluble epoxide hydrolases: Purification, biochemical characterization, and comparison to mammalian enzymes. Archives of Biochemistry and Biophysics.   378(2):321-332.
  • Nakagawa, Yoshiaki, Craig E. Wheelock, Christophe Morisseau, Marvin H. Goodrow, Bruce G. Hammock, and Bruce D. Hammock. 2000. 3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues. Bioorganic & Medicinal Chemistry.   8(11):2663-2673.
  • Shan, Guomin, Wei Huang, Shirley J. Gee, Bruce A. Buchholz, John S. Vogel, and Bruce D. Hammock. 2000. Isotope-labeled immunoassays without radiation waste. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   97(6):2445-2449.
  • Shan, Guomin, Whitney R. Leeman, Donald W. Stoutamire, Shirley J. Gee, Daniel PY Chang, and Bruce D. Hammock. 2000. Enzyme-linked immunosorbent assay for the pyrethroid permethrin. Journal of Agricultural and Food Chemistry.   48(9):4032-4040.
  • Shan, Guomin, James R. Sanborn, Douglas S. Gilman, Scott R. Nagy, Shirley J. Gee, Donald W. Stoutamire, Roger S. Mercer, A. Daniel Jones, Larry H. Stanker, Michael S. Denison, and Bruce D. Hammock. 2000. Surrogates for dioxin analyses: analytical, ELISA and toxicological aspects. Organohalogen Compounds. 45:188-191.
  • Williamson, Kenneth, Christophe Morisseau, Joseph E. Maxwell, and Bruce D. Hammock. 2000. Regio- and enantioselective hydrolysis of phenyloxiranes catalyzed by soluble epoxide hydrolase. Tetrahedron: Asymmetry.   11:4451-4462.
  • Yamada, Takashi, Christophe Morisseau, Joseph E. Maxwell, Maria A. Argiriadi, David W. Christianson, and Bruce D. Hammock. 2000. Biochemical evidence for the involvement of tyrosine in epoxide activation during the catalytic cycle of epoxide hydrolase. Journal of Biological Chemistry.   275(30):23082-23088.
  • Yu, Zhigang, Fengyun Xu, Linn M. Huse, Christophe Morisseau, Alison J. Draper, John W. Newman, Carol Parker, LeRae Graham, Marguerite M. Engler, Bruce D. Hammock, Darryl C. Zeldin, and Deanna L. Kroetz. 2000. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circulation Research.   87(11):992-998.
1999
  • Argiriadi, Maria A., Christophe Morisseau, Bruce D. Hammock, and David W. Christianson. 1999. Detoxification of environmental mutagens and carcinogens: Structure, mechanism, and evolution of liver epoxide hydrolase. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   96:10637-10642.
  • Buchholz, Bruce A., Ester Fultz, Kurt W. Haack, John S. Vogel, Douglas S. Gilman, Shirley J. Gee, Bruce D. Hammock, Xiaoying Hui, Ronald C. Wester, and Howard I. Maibach. 1999. HPLC-accelerator MS measurement of atrazine metabolites in human urine after dermal exposure. Analytical Chemistry.   71(16):3519-3525.
  • Draper, Alison J. and Bruce D. Hammock. 1999. Inhibition of soluble and microsomal epoxide hydrolase by zinc and other metals. Toxicological Sciences.   52:26-32.
  • Draper, Alison J. and Bruce D. Hammock. 1999. Soluble epoxide hydrolase in rat inflammatory cells is indistinguishable from soluble epoxide hydrolase in rat liver. Toxicological Sciences.   50:30-35.
  • Kido, Horacio, Ferenc Szurdoki, M.S. Gustin, and Bruce D. Hammock. 1999. Chelate sensor method for mercury. In: Metals and Genetics. Kluwer Academic/Plenum Press, NY. pp.235-259.
  • Morisseau, Christophe, Maher Derbel, Terry R. Lane, Donald W. Stoutamire, and Bruce D. Hammock. 1999. Differential induction of hepatic drug-metabolizing enzymes by fenvaleric acid in male rats. Toxicological Sciences.   52(2):148-153.
  • Morisseau, Christophe, Marvin H. Goodrow, Deanna L. Dowdy, Jiang Zheng, Jessica F. Greene, James R. Sanborn, and Bruce D. Hammock. 1999. Potent urea and carbamate inhibitors of soluble epoxide hydrolases. Proceedings of the National Academy of Sciences of the United States of America (PNAS).   96(16):8849-8854.
  • Morisseau, Christophe, Barney L. Ward, David G. Gilchrist, and Bruce D. Hammock. 1999. Multiple epoxide hydrolases in Alternaria alternata f. sp. lycopersici and their relationship to medium composition and host-specific toxin production. Applied and Environmental Microbiology.   65(6):2388-2395.
  • Mullen, Robert T., Richard N. Trelease, Heike Duerk, Michael Arand, Bruce D. Hammock, Franz Oesch, and David F. Grant. 1999. Differential subcellular localization of endogenous and transfected soluble epoxide hydrolase in mammalian cells: evidence for isozyme variants. FEBS Letters.   445(2-3):301-305.
  • Shan, Guomin, Donald W. Stoutamire, Shirley J. Gee, Ingrid Wengatz, and Bruce D. Hammock. 1999. Development of an immunoassay for the pyrethroid insecticide esfenvalerate. Journal of Agricultural and Food Chemistry.   47(5):2145-2155.
  • Shan, Guomin, Ingrid Wengatz, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock. 1999. An enzyme-linked immunosorbent assay for the detection of esfenvalerate metabolites in human urine. Chemical Research in Toxicology.   12(11):1033-1041.
  • Thomas, Beth Ann, W. Bret Church, Terry R. Lane, and Bruce D. Hammock. 1999. Homology model of juvenile hormone esterase from the crop pest, Heliothis virescens. Proteins: Structure, Function, and Genetics. 34(2):184-196.
  • Yazynina, Elena V., Anatoliy V. Zherdev, Boris B. Dzantiev, Vladimir A. Izumrudov, Shirley J. Gee, and Bruce D. Hammock. 1999. Immunoassay techniques for detection of the herbicide simazine based on use of oppositely charged water-soluble polyelectrolytes. Analytical Chemistry.   71(16):3538-3543.
  • Yazynina, Elena V., Anatoliy V. Zherdev, Boris B. Dzantiev, Vladimir A. Izumrudov, Shirley J. Gee, and Bruce D. Hammock. 1999. Microplate immunoassay technique using polyelectrolyte carriers: kinetic studies and application to detection of the herbicide atrazine. Analytica Chimica Acta.   399(1-2):151-160.
1998
  • Gilman, Douglas S., Shirley J. Gee, Bruce D. Hammock, John S. Vogel, Kurt W. Haack, Bruce A. Buchholz, Stewart PHT Freeman, Ronald C. Wester, Xiaoying Hui, and Howard I. Maibach. 1998. Analytical performance of accelerator mass spectrometry and liquid scintillation counting for detection of 14C-labeled atrazine metabolites in human urine. Analytical Chemistry.   70(16):3463-3469.
  • Goodrow, Marvin H. and Bruce D. Hammock. 1998. Hapten design for compound-selective antibodies: ELISA's for environmentally deleterious small molecules. Analytica Chimica Acta.   376(1):83-91.
  • Harris, Adam S., Ingrid Wengatz, Monika Wortberg, Sabine B. Kreissig, Shirley J. Gee, and Bruce D. Hammock. 1998. Development and application of immunoassays for biological and environmental monitoring. In: Effects of Multiple Impacts on Ecosystems. Lewis Publishers, Chelsea, MI. pp.135-153.
  • Jaeger, Lynn L., A. Daniel Jones, and Bruce D. Hammock. 1998. Development of an enzyme-linked immunosorbent assay for atrazine mercapturic acid in human urine. Chemical Research in Toxicology.   11(4):342-352.
  • Marco, Maria-Pilar, Shirley J. Gee, and Bruce D. Hammock. 1998. Determination of 1-naphthol in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C.9.1-2C.9.11.
  • Marco, Maria-Pilar, Shirley J. Gee, and Bruce D. Hammock. 1998. Determination of carbaryl in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C8.1-2C8.15.
  • Mitchell, Alyson E., Jiang Zheng, Bruce D. Hammock, Mario Lo Bello, and A. Daniel Jones. 1998. Structural and functional consequences of haloenol lactone inactivation of murine and human glutathione S-transferase. Biochemistry.   37(19):6752-6759.
  • Reimer, Gerry J., Shirley J. Gee, and Bruce D. Hammock. 1998. Comparison of a time-resolved fluorescence immunoassay and an enzyme-linked immunosorbent assay for the analysis of atrazine in water. Journal of Agricultural and Food Chemistry.   46(8):3353-3358.
  • Sanborn, James R., Shirley J. Gee, Douglas S. Gilman, Yukio Sugawara, A. Daniel Jones, J. Rogers, Ferenc Szurdoki, Larry H. Stanker, Donald W. Stoutamire, and Bruce D. Hammock. 1998. Hapten synthesis and antibody development for polychlorinated dibenzo-p-dioxin immunoassays. Journal of Agricultural and Food Chemistry.   46:2407-2416.
  • Sugawara, Yukio, Shirley J. Gee, James R. Sanborn, Douglas S. Gilman, and Bruce D. Hammock. 1998. Development of a highly sensitive enzyme-linked immunosorbent assay based on polyclonal antibodies for the detection of polychlorinated dibenzo-p-dioxins. Analytical Chemistry.   70(6):1092-1099.
  • Wengatz, Ingrid, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock. 1998. Development of an enzymelinked immunosorbent assay for the detection of the pyrethroid insecticide fenpropathrin. Journal of Agricultural and Food Chemistry.   46(6):2211-2221.
1997
  • Jones, Geoffrey, Monika Wortberg, David M. Rocke, and Bruce D. Hammock. 1997. Immunoassay of cross-reacting analytes. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.331-342.
  • Kido, Horacio, Marvin H. Goodrow, Valerie Griffeth, Ann D. Lucas, Shirley J. Gee, and Bruce D. Hammock. 1997. Development of an enzyme-linked immunosorbent assay for the detection of hydroxytriazines. Journal of Agricultural and Food Chemistry.   45(2):414-424.
  • Moghaddam, Mehran F., David F. Grant, Jeffrey M. Cheek, Jessica F. Greene, Kenneth Williamson, and Bruce D. Hammock. 1997. Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase. Nature Medicine.   3(5):562-566.
  • Schutz, S., Ingrid Wengatz, Marvin H. Goodrow, Shirley J. Gee, Hans E. Hummel, and Bruce D. Hammock. 1997. Development of an enzyme-linked-immunosorbent assay for azadirachtins. Journal of Agricultural and Food Chemistry.   45(6):2363-2368.
  • Swamy, Anand R., M.I. Danesvar, L. Evans, III, L. Strekowski, N. Narayanan, Ferenc Szurdoki, Ingrid Wengatz, Bruce D. Hammock, and Gabor Patonay. 1997. Near-infrared fluorescent immunoassays: A novel approach to environmental analysis. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.141-161.
  • Szurdoki, Ferenc, Horacio Kido, and Bruce D. Hammock. 1997. Rapid mercury assays. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.38-48.
  • Zheng, Jiang, Myung Cho, A. Daniel Jones, and Bruce D. Hammock. 1997. Evidence of quinone metabolites of naphthalene covalently bound to sulfur nucleophiles of proteins of murine clara cells after exposure to naphthalene. Chemical Research in Toxicology.   10(9):1008-1014.
1996
  • Grant, David F., Jessica F. Greene, Frank Pinot, Babak Borhan, Mehran F. Moghaddam, Bruce D. Hammock, Bill McCutchen, Hideo Ohkawa, Gang Luo, and Thomas M. Guenthner. 1996. Development of an in situ toxicity assay system using recombinant baculoviruses. Biochemical Pharmacology.   51(4):503-515.
  • Jones, Geoffrey, Monika Wortberg, Bruce D. Hammock, and David M. Rocke. 1996. A procedure for the immunoanalysis of samples containing one or more members of a group of cross-reacting analytes. Analytica Chimica Acta.   336(1-3):175-183.
  • Jones, Geoffrey, Monika Wortberg, Sabine B. Kreissig, Bruce D. Hammock, and David M. Rocke. 1996. Application of the bootstrap to calibration experiments. Analytical Chemistry.   68(5):763-770.
  • Linde, C.D., Shirley J. Gee, Kean S. Goh, Jean C. Hsu, Bruce D. Hammock, Terrell A. Barry, and Don J. Weaver. 1996. Regulatory application of ELISA: Compliance monitoring of bromacil in soil. Bulletin of Environmental Contamination and Toxicology.   57(2):264-269.
  • Szurdoki, Ferenc, Lynn L. Jaeger, Adam S. Harris, Horacio Kido, Ingrid Wengatz, Marvin H. Goodrow, Andras Szekacs, Monika Wortberg, Jiang Zheng, Donald W. Stoutamire, James R. Sanborn, Douglas S. Gilman, A. Daniel Jones, Shirley J. Gee, Prabahakara Choudary, and Bruce D. Hammock. 1996. Rapid assays for environmental and biological monitoring. Journal of Environmental Science and Health.   31(3):451-458.
  • Wengatz, Ingrid, Adam S. Harris, Douglas S. Gilman, Monika Wortberg, Horacio Kido, Ferenc Szurdoki, Marvin H. Goodrow, L. Jaeger, Donald W. Stoutamire, James R. Sanborn, Shirley J. Gee, and Bruce D. Hammock. 1996. Recent developments in immunoassays and related methods for the detection of xenobiotics. In: Environmental Immunochemical Methods, Perspectives and Applications. ACS Symposium Series No. 646, American Chemical Society, Washington, DC. pp.110-126.
  • Wortberg, Monika, Marvin H. Goodrow, Shirley J. Gee, and Bruce D. Hammock. 1996. Immunoassay for simazine and atrazine with low cross-reactivity for propazine. Journal of Agricultural and Food Chemistry.   44(8):2210-2219.
  • Wortberg, Monika, Geoffrey Jones, Sabine B. Kreissig, David M. Rocke, Shirley J. Gee, and Bruce D. Hammock. 1996. An approach to the construction of an immunoarray for differentiating and quantitating cross reacting analytes. Analytica Chimica Acta.   319(3):291-303.
  • Zheng, Jiang and Bruce D. Hammock. 1996. Development of polyclonal antibodies for detection of protein modification by 1,2-naphthoquinone. Chemical Research in Toxicology.   9(5):904-909.
  • Zheng, Jiang, Alyson E. Mitchell, A. Daniel Jones, and Bruce D. Hammock. 1996. Haloenol lactone is a new isozyme-selective and active site-directed inactivator of glutathione S-transferase. Journal of Biological Chemistry.   271(34):20421-20425.
1995
  • Borhan, Babak, A. Daniel Jones, Frank Pinot, David F. Grant, Mark Kurth, and Bruce D. Hammock. 1995. Mechanism of soluble epoxide hydrolase. Formation of An a-hydroxy ester-enzyme intermediate through Asp-333. Journal of Biological Chemistry.   270(45):26923-26930.
  • Choudary, Prabahakara, Heather A. Lee, Bruce D. Hammock, and Michael RA Morgan. 1995. Recombinant antibodies: New tools for immunoassays. Chapter 13 in: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.171-185.
  • Gee, Shirley J., Bruce D. Hammock, and John H. Skerritt. 1995. Diagnostics for plant agrochemicals--a meeting of chemistry and immunoassay. In: New Diagnostics in Crop Sciences. CAB International, Oxon, United Kingdom. pp.243-276.
  • Gee, Shirley J., Ann D. Lucas, and Bruce D. Hammock. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Proceedings of the NATO (North Atlantic Treaty Organisation) Workshop on Methods of Pesticide Exposure Assessment. Ottawa, Canada.
  • Gee, Shirley J., Ann D. Lucas, and Bruce D. Hammock. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Methods of Pesticide Exposure Assessment. Plenum Press, NY. pp.143-155.
  • Goodrow, Marvin H., James R. Sanborn, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock. 1995. Strategies for immunoassay hapten design. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.119-139.
  • Hammock, Bruce D. and Shirley J. Gee. 1995. Impact of emerging technologies on immunochemical methods for environmental analysis. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.1-19.
  • Harris, Adam S., Ann D. Lucas, Petra M. Kramer, Maria-Pilar Marco, Shirley J. Gee, and Bruce D. Hammock. 1995. Use of immunoassay for the detection of urinary biomarkers of exposure. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.217-235.
  • Jones, Geoffrey, Monika Wortberg, Sabine B. Kreissig, Bruce D. Hammock, and David M. Rocke. 1995. Sources of experimental variation in calibration curves for enzyme-linked immunosorbent assay. Analytica Chimica Acta.   313:197-207.
  • Kreissig, Sabine B., Vernon K. Ward, Bruce D. Hammock, and Prabahakara Choudary. 1995. Nucleotide sequence of the variable region of the heavy and light chains of a monoclonal lgG antibody reactive to herbicides, terbutryn and prometryn. DNA Sequence.   6:51-54.
  • Kreissig, Sabine B., Vernon K. Ward, Bruce D. Hammock, and Prabahakara Choudary. 1995. Sequence analysis of individual chains of antibodies to triazine herbicides. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.31-49.
  • Lucas, Ann D., Shirley J. Gee, Bruce D. Hammock, and James N. Seiber. 1995. Integration of immunochemical methods with other analytical techniques for pesticide residue determination. Journal of AOAC International.   78(3):585-591.
  • Lucas, Ann D., Marvin H. Goodrow, James N. Seiber, and Bruce D. Hammock. 1995. Development of an ELISA for the N-dealkylated s-triazines: Application to environmental and biological samples. Food & Agricultural Immunology.   7:227-241.
  • Marco, Maria-Pilar, Serge Chiron, Jordi Gascon, Bruce D. Hammock, and Damia Barcelo. 1995. Validation of two immunoassay methods for environmental monitoring of carbaryl and 1-naphthol in ground water samples. Analytica Chimica Acta.   311(3):319-329.
  • Schneider, P., Shirley J. Gee, Sabine B. Kreissig, Adam S. Harris, Petra M. Kramer, Maria-Pilar Marco, Ann D. Lucas, and Bruce D. Hammock. 1995. Troubleshooting during the development and use of immunoassays for environmental monitoring. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.103-122.
  • Sundaram, K.MS, A. Sundaram, Shirley J. Gee, R.O. Harrison, and Bruce D. Hammock. 1995. Enzyme-linked immunosorb and assay for quantification of Bacillus thuringiensis var. kurstaki crystaline protein in commerical formulations, in relation to total protein content and insecticidal activity. In: Pesticide Formulations and Applicaiton Systems, 14th Volume. American Society for Testing and Materials, Philadelphia, PA.
  • Szekacs, Andras and Bruce D. Hammock. 1995. Development of an enzyme-linked immunosorbent assay for the detection of the triazole fungicide myclobutanil. Journal of Agricultural and Food Chemistry.   43(8):2083-2091.
  • Szekacs, Andras, F. Jung, and Bruce D. Hammock. 1995. Chemical modification of haptens: Selective amino group protection by chromophores for an immunoassay for aminotriazoles. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.65-75.
  • Szurdoki, Ferenc, Hassan KM Bekheit, Maria-Pilar Marco, Marvin H. Goodrow, and Bruce D. Hammock. 1995. Important factors in hapten design and enzyme-linked immunosorbent assay development. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.39-63.
  • Szurdoki, Ferenc, Horacio Kido, and Bruce D. Hammock. 1995. Development of assay for analysis of Hg2+ based on sulfur-containing ligands. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.248-264.
  • Szurdoki, Ferenc, Horacio Kido, and Bruce D. Hammock. 1995. Development of rapid mercury assays. Synthesis of sulfur-and mercury-containing conjugates. Bioconjugate Chemistry.   6(2):145-149.
  • Ward, Vernon K., Bruce D. Hammock, Shin Maeda, and Prabahakara Choudary. 1995. Development and application of recombinant antibodies to pesticide residue analysis. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.197-216.
  • Ward, Vernon K., Sabine B. Kreissig, Bruce D. Hammock, and Prabahakara Choudary. 1995. Generation of an expression library in the baculovirus expression vector system. Journal of Virological Methods.   53(2-3):263-272.
  • Wengatz, Ingrid, Ferenc Szurdoki, Anand R. Swamy, Lawrence Evans, Gabor Patonay, Eric Stimman, Michael Delwiche, Donald W. Stoutamire, Shirley J. Gee, and Bruce D. Hammock. 1995. Immunoassays for pesticide monitoring. SPIE Proceedings, San Jose, CA. 408-416.
  • Wortberg, Monika, Sabine B. Kreissig, Geoffrey Jones, David M. Rocke, and Bruce D. Hammock. 1995. An immunoarray for the simultaneous determination of multiple triazine herbicides. Analytica Chimica Acta.   304:339-352.