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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Patent Detail: Epoxide Hydrolase Inhibitor Methods

Patent Detail

Superfund Research Program

Epoxide Hydrolase Inhibitor Methods

Number: 6,174,695
Year: 2001
Patent Status: Issued
Authors: Hammock, B.D., M.F. Moghaddam, J.M. Cheek, B. Borhan, J. Fergusson, D.F. Grant, J.F. Greene, K. Matoba, J. Zheng, M.F. Sisemore

The present invention provides methods of treating inflammatory diseases mediated by poly-unsaturated lipid metabolites by inhibiting epoxide hydrolase, methods for assaying or screening the epoxide hydrolase inhibitors for inhibitory specificity and for toxicity, and novel biologically active tetrahydrofuran diols of arachidonic acid, including antibodies thereto.

Associated Projects:

  • University of California-Davis: Immunoassays for Human and Environmental Health Monitoring
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