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Your Environment. Your Health.

Landscape, environmental and social predictors of Hantavirus risk in Sao Paulo, Brazil

Climate Change and Human Health Literature Portal

Author(s):   Prist PR, Uriarte M, Tambosi LR, Prado A, Pardini R, D'Andrea PS, Metzger JP
Year:   2016
Journal:   PLoS One. 11 (10): e0163459

Source: http://dx.doi.org/10.1371/journal.pone.0163459   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079598/  

Abstract:

Hantavirus Pulmonary Syndrome (HPS) is a disease caused by Hantavirus, which are negative-sense RNA viruses in the family Bunyaviridae that are highly virulent to humans. Numerous factors modify risk of Hantavirus transmission and consequent HPS risk. Human-driven landscape change can foster transmission risk by increasing numbers of habitat generalist rodent species that serve as the principal reservoir host. Climate can also affect rodent population dynamics and Hantavirus survival, and a number of social factors can influence probability of HPS transmission to humans. Evaluating contributions of these factors to HPS risk may enable predictions of future outbreaks, and is critical to development of effective public health strategies. Here we rely on a Bayesian model to quantify associations between annual HPS incidence across the state of Sao Paulo, Brazil (1993-2012) and climate variables (annual precipitation, annual mean temperature), landscape structure metrics (proportion of native habitat cover, number of forest fragments, proportion of area planted with sugarcane), and social factors (number of men older than 14 years and Human Development Index). We built separate models for the main two biomes of the state (cerrado and Atlantic forest). In both biomes Hantavirus risk increased with proportion of land cultivated for sugarcane and HDI, but proportion of forest cover, annual mean temperature, and population at risk also showed positive relationships in the Atlantic forest. Our analysis provides the first evidence that social, landscape, and climate factors are associated with HPS incidence in the Neotropics. Our risk map can be used to support the adoption of preventive measures and optimize the allocation of resources to avoid disease propagation, especially in municipalities that show medium to high HPS risk (> 5% of risk), and aimed at sugarcane workers, minimizing the risk of future HPS outbreaks.

Resource Description

  • Cross-cutting Themes: Adaptation, Mitigation , Vulnerable Population
  • Exposure : What is this?

    weather or climate related pathway by which climate change affects health

    Ecosystem Change, Precipitation, Temperature
  • Temperature: Heat
  • Geographic Feature: What is this?

    resource focuses on specific type of geography

    Forest
  • Geographic Location: What is this?

    resource focuses on specific location

    Non-United States
  • Non-United States: Central and South America
  • Health Impact: What is this?

    specification of health effect or disease related to climate change exposure

    Infectious Disease, Morbidity/Mortality
  • Infectious Disease: Zoonotic Disease
  • Zoonotic Disease: Hantavirus Pulmonary Syndrome
  • Resource Type: What is this?

    format or standard characteristic of resource

    Research Article
  • Adaptation: Intervention
  • Vulnerable Population: Workers
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