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Study Information
Study Attribute Value
CEBS Accession Number: 002-02182-0001-0000-6
Chemical Name: Fluorotelomer Alcohol 8+2
CASRN: 678-39-7
NTP Study Type: Genetic Toxicology - Bacterial Mutagenicity
NTP Study ID: A74889
Vehicle Control: Dimethyl Sulfoxide
Study Result: Negative

Table Instructions and Notes:
You are currently viewing the results for this Salmonella study's detailed data.
Individual strain data is presented as mean ± standard error.
Abbreviations are noted at bottom of page.
Trial summary calls are shown in parentheses.
Standard NTP Protocol

Strain: TA100
Dose No Activation
(Negative) 		No Activation
(Negative) 		10% RLI
(Negative) 		10% RLI
(Negative)
Protocol Preincubation Preincubation Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM 
 0         
 61 2.6 50 3.8 53 3 73 5 
1000         
 58 1.9 36 6.9 41 4.2 55 1.5 
2500         
 59 8.8 44 4.3 44 2.8 49 4 
5000         
 61 2.2 44 4.3 49 .9 55 2.3 
7500         
 51 3.7 48 1.7 53 4.8 55 5.2 
10000         
 81 15.9 46 4.2 59 6.2 53 7.9
Positive Control 269 2.7 211 10.7 719 48.6 915 29.2

Strain: TA98
Dose No Activation
(Negative) 		No Activation
(Negative) 		10% RLI
(Negative) 		10% RLI
(Negative)
Protocol Preincubation Preincubation Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM 
 0         
 17 2.5 18 4.3 18 2.5 28 3.7 
1000         
 18 3 17 .3 18 2 22 3.8 
2500         
 14 1.9 16 3.5 20 .9 28 2.9 
5000         
 16 1.2 15 4.4 17 3.5 30 2 
7500         
 15 1.5 21 2 20 3.2 22 2.7 
10000         
 16 2.9 16 3.3 18 2.5 28 3.8
Positive Control 218 22.7 516 13.8 992 26.7 790 13.3

Strain: eColi pKM101
Dose No Activation
(Negative) 		No Activation
(Negative) 		10% RLI
(Negative) 		10% RLI
(Negative)
Protocol Preincubation Preincubation Preincubation Preincubation
ug/Plate Mean ±SEM Mean ±SEM Mean ±SEM Mean ±SEM 
 0         
 233 11.1 226 9.3 257 5.4 248 8.1 
1000         
 206 14.9 220 4.3 240 15.6 267 4.8 
2500         
 208 1.9 225 3.1 251 8 212 53.5 
5000         
 219 3 223 6.2 245 12.6 259 5.2 
7500         
 214 4.5 239 5.2 235 16.5 252 8.4 
10000         
 214 10.1 234 4.4 233 2 256 6.8
Positive Control 687 34.3 624 7.8 728 91.8 765 37.4

Abbreviations:
RLI = induced male Sprague Dawley rat liver S9
HLI = induced male Syrian hamster liver S9
s = Slight Toxicity; p = Precipitate; x = Slight Toxicity and Precipitate; t = Toxic;