| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01076-0013-0000-0 |
| Chemical Name: | 1,3-Dichloropropene (Telone II) |
| CASRN: | 542-75-6 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 208737_SCE |
| Study Result: | Negative (Nonstandard Protocol) |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 01/13/87 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
| Dose (mg/kg) |
n | SCE / Cell (Mean ± SEM) |
Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 |
4 | 6.28 ± 0.860 | |
| Test Chemical | 1,3-Dichloropropene (Telone II) | 50 |
4 | 5.15 ± 0.396 | |
100 |
4 | 4.92 ± 0.462 | |||
200 |
3 | 6.74 ± 0.264 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 |
4 | 9.29 ± 0.314 | |
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 02/22/88 | 42 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 42 hour |
| Dose (mg/kg) |
n | SCE / Cell (Mean ± SEM) |
Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Corn Oil | 0 |
4 | 6.21 ± 1.911 | |
| Test Chemical | 1,3-Dichloropropene (Telone II) | 50 |
4 | 4.23 ± 1.034 | |
100 |
4 | 4.30 ± 0.389 | |||
200 |
4 | 3.79 ± 0.489 | |||
| Positive Control | Dimethylbenzanthracene | 2.5 |
4 | 7.97 ± 1.391 | |
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed