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Study Information
Study Attribute Value
CEBS Accession Number: 002-02042-0014-0000-5
Chemical Name: Diethylstilbestrol
CASRN: 56-53-1
NTP Study Type: Genetic Toxicology - Micronucleus
NTP Study ID: A66561
Strain and Species: Tg.AC Mouse
Study Result: Male: Negative; Female: Negative

Blood

Start Date Sample Collection Time Sex Cell Methodology Used Dosing Regimen Route Trend Test P-Value
2000-04-25 24 hour Female NCE Slide Scoring Gavage x 52, 26 week Gavage 0.156
  Dose (ug/kg) Number of Animals Scored Mean MN-NCE/1000 NCE ± SEM Pairwise P
Vehicle Control Corn Oil 
 0         
 8 1.190 ± 0.350
Test Chemical Diethylstilbestrol 
30         
 12 1.290 ± 0.210 0.386 
240         
 11 0.770 ± 0.170 0.903 
480         
 8 1.750 ± 0.250 0.095

Blood

Start Date Sample Collection Time Sex Cell Methodology Used Dosing Regimen Route Trend Test P-Value
2000-04-25 24 hour Male NCE Slide Scoring Gavage x 52, 26 week Gavage 0.237
  Dose (ug/kg) Number of Animals Scored Mean MN-NCE/1000 NCE ± SEM Pairwise P
Vehicle Control Corn Oil 
 0         
 12 1.000 ± 0.190
Test Chemical Diethylstilbestrol 
30         
 11 1.320 ± 0.250 0.158 
240         
 13 0.730 ± 0.170 0.848 
480         
 12 1.420 ± 0.270 0.094