| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02194-0016-0000-5 |
| Chemical Name: | Furfural |
| CASRN: | 98-01-1 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 991433_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below is a summary of Sister Chromatid Exchange data. Use the link below the summary tables to view detailed data for that specific trial.
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 02/12/87 | 23 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 23 hour |
| Dose (mg/kg) |
n | SCE / Cell (Mean ± SEM) |
Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Phosphate Buffered Saline | 0 |
4 | 4.02 ± 0.216 | |
| Test Chemical | Furfural | 50 |
4 | 4.84 ± 0.477 | |
100 |
4 | 3.44 ± 0.392 | |||
200 |
4 | 4.18 ± 0.291 | |||
| Positive Control | Mitomycin-C | 0.5 |
4 | 7.11 ± 0.494 | |
| Test Type | Start Date | Sample Time (h) | Species | Sex | Strain | Tissue | Protocol | Trend Test P |
|---|---|---|---|---|---|---|---|---|
| SCE | 08/18/87 | 42 | Mouse | Male | B6C3F1 | Bone Marrow | IP/IJ x 1, 42 hour |
| Dose (mg/kg) |
n | SCE / Cell (Mean ± SEM) |
Pairwise P | ||
|---|---|---|---|---|---|
| Vehicle Control | Phosphate Buffered Saline | 0 |
3 | 5.17 ± 0.932 | |
| Test Chemical | Furfural | 50 |
4 | 4.30 ± 0.273 | |
100 |
4 | 3.83 ± 0.343 | |||
200 |
4 | 4.05 ± 0.315 | |||
| Positive Control | Mitomycin-C | 0.5 |
4 | 4.00 ± 0.145 | |
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed