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Study Information
Study Attribute Value
CEBS Accession Number: 002-02810-0002-0000-5
Chemical Name: Sodium azide
CASRN: 26628-22-8
NTP Study Type: Genetic Toxicology - Mammalian Cell Cytogenetics
NTP Study ID: 166603_CA
Study Result: Negative

Study Result: Negative
Activation Trial Trial Call
No Activation  1  Negative 
Induced Rat Liver S9  1_S9  Negative 

Trial #:1   Activation: No Activation    Date: 11/18/1987    Harvest Time: 20.3 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Negative (Not Specified) 
0         
 200 2 0.010 1.0 0 0.000 0.0 2 0.010 1.0 0 0.000 0.0
Negative (Not Specified) 
0         
 200 4 0.020 2.0 2 0.010 1.0 2 0.010 1.0 0 0.000 0.0
Test Chemical: Sodium azide 
20         
 200 2 0.010 1.0 0 0.000 0.0 2 0.010 1.0 0 0.000 0.0 
30         
 200 9 0.045 3.5 0 0.000 0.0 9 0.045 3.5 0 0.000 0.0 
40         
 200 2 0.010 1.0 1 0.005 0.5 1 0.005 0.5 0 0.000 0.0
Positive Control: Mitomycin-C 
 0.05      
 200 30 0.150 13.5 8 0.040 4.0 22 0.110 10.0 0 0.000 0.0
Mitomycin-C 
 0.08      
 25 24 0.960 52.0 10 0.400 40.0 4 0.160 12.0 10 0.400 4.0
Trend: 0.012 -0.826 0.429  
Probability: 0.495 0.796 0.334  


Trial #:1_S9   Activation: Induced Rat Liver S9    Date: 11/17/1987    Harvest Time: 12 hour(s)   Trial Call: Negative   
  Dose
µg/mL		 Total
Cells Examined		 Total Aberrations Complex Aberrations Simple Aberrations Other Abs
No. of
Abs		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs		 No. of
Abs.		 Abs
Per
Cell		 % Cells
With
Abs
Vehicle Control: Negative (Not Specified) 
0         
 200 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Negative (Not Specified) 
0         
 200 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Test Chemical: Sodium azide 
2020         
 200 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 
3015         
 200 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 
4020         
 200 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0 0 0.000 0.0
Positive Control: Cyclophosphamide 
7.5       
 200 19 0.095 9.5 6 0.030 3.0 13 0.065 6.5 0 0.000 0.0
Cyclophosphamide 
37.5       
 25 11 0.440 40.0 5 0.200 20.0 6 0.240 24.0 0 0.000 0.0
Trend: 0.000 0.000 0.000  
Probability: 0.000 0.000 0.000