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Study Information
Study Attribute Value
CEBS Accession Number: 002-02857-0010-0000-5
Chemical Name: Sulfapyridine
CASRN: 144-83-2
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: A49990_CA
Study Result: Negative (Nonstandard Protocol)

View Detailed Data
Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 01/16/92 24 Mouse Male Bone Marrow Gavage x 1/study, 24 hour 0.0000
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
150         
 0 0.00 ± 0.00 0.0000
Test Chemical Sulfapyridine 
500         
 0 0.00 ± 0.00 0.0000
  
1000         
 0 0.00 ± 0.00 0.0000
  
2000         
 0 0.00 ± 0.00 0.0000
Vehicle Control No Stressor 
 0         
 0 0.00 ± 0.00 0.0000


View Detailed Data
Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 02/11/92 72 Mouse Male Bone Marrow Gavage x 3/study, 72 hour 0.8234
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 15.75 ± 2.09 0.0000
Test Chemical Sulfapyridine 
500         
 8 1.00 ± 0.38 0.8777
  
1000         
 8 6.45 ± 0.56 0.6728
  
2000         
 8 1.00 ± 0.53 0.8777
Vehicle Control No Stressor 
 0         
 8 2.00 ± 0.53 0.0000


View Detailed Data
Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 12/22/92 17 Mouse Male Bone Marrow Gavage x 1/study, 17 hour 0.6841
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 3.75 ± 2.02 0.0002
Test Chemical Sulfapyridine 
500         
 8 1.00 ± 0.53 0.0892
  
1000         
 8 0.50 ± 0.33 0.2815
  
2000         
 8 0.25 ± 0.25 0.5000
Vehicle Control No Stressor 
 0         
 8 0.25 ± 0.25 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed