| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02797-0014-0000-2 |
| Chemical Name: | Selenium sulfide |
| CASRN: | 7446-34-6 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 023793_SCE |
| Study Result: | Positive |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 04/18/1989 | Bone Marrow | 42 | Male | Mouse | B6C3F1 | IP/IJ x 1, 42 hour | Positive |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
11770 | 25 | 6.72 | ± | 0.368 |
| 11781 | 25 | 7.74 | ± | 0.970 | |||
| 11799 | 24 | 6.18 | ± | 0.494 | |||
| 11811 | 25 | 5.93 | ± | 0.782 | |||
| Average | 6.65 | ± | 0.403 | ||||
| Test Chemical | Selenium sulfide |
11.25 |
11804 | 25 | 10.61 | ± | 0.924 |
| 11805 | 25 | 11.08 | ± | 1.009 | |||
| 11814 | 25 | 10.88 | ± | 0.807 | |||
| 11817 | 25 | 10.23 | ± | 0.845 | |||
| Average | 10.70 | ± | 0.183 | ||||
| Test Chemical | Selenium sulfide |
15 |
11807 | 25 | 7.96 | ± | 0.670 |
| 11810 | 25 | 11.70 | ± | 0.832 | |||
| 11813 | 25 | 15.86 | ± | 0.932 | |||
| 11816 | 25 | 7.41 | ± | 0.703 | |||
| Average | 10.73 | ± | 1.957 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
11765 | 25 | 14.72 | ± | 1.341 |
| 11777 | 25 | 17.41 | ± | 1.129 | |||
| 11803 | 25 | 15.87 | ± | 1.680 | |||
| 11806 | 25 | 18.80 | ± | 1.971 | |||
| Average | 16.69 | ± | 0.892 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed