| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02202-0012-0000-1 |
| Chemical Name: | Geranyl acetate |
| CASRN: | 105-87-3 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 125080_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 01/13/1987 | Bone Marrow | 23 | Male | Mouse | B6C3F1 | IP/IJ x 1, 23 hour | Negative |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
4955 | 25 | 8.78 | ± | 0.642 |
| 4956 | 25 | 5.63 | ± | 0.425 | |||
| 4957 | 25 | 4.85 | ± | 0.580 | |||
| 4958 | 25 | 5.86 | ± | 0.565 | |||
| Average | 6.28 | ± | 0.860 | ||||
| Test Chemical | Geranyl acetate |
425 |
4926 | 25 | 6.09 | ± | 0.676 |
| 4927 | 25 | 4.98 | ± | 0.411 | |||
| 4928 | 25 | 4.98 | ± | 0.442 | |||
| Average | 5.35 | ± | 0.371 | ||||
| Test Chemical | Geranyl acetate |
850 |
4930 | 25 | 4.85 | ± | 0.604 |
| 4932 | 25 | 3.73 | ± | 0.346 | |||
| 4933 | 25 | 8.17 | ± | 0.513 | |||
| 4934 | 25 | 4.77 | ± | 0.352 | |||
| Average | 5.37 | ± | 0.965 | ||||
| Test Chemical | Geranyl acetate |
1700 |
4935 | 25 | 7.84 | ± | 0.548 |
| 4937 | 25 | 6.22 | ± | 0.453 | |||
| 4938 | 25 | 6.54 | ± | 0.614 | |||
| 4939 | 25 | 7.60 | ± | 0.834 | |||
| Average | 7.04 | ± | 0.395 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
4960 | 25 | 9.40 | ± | 0.738 |
| 4962 | 25 | 9.72 | ± | 0.771 | |||
| 4963 | 25 | 8.37 | ± | 0.727 | |||
| 4964 | 25 | 9.68 | ± | 0.795 | |||
| Average | 9.29 | ± | 0.314 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed