| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02202-0012-0000-1 |
| Chemical Name: | Geranyl acetate |
| CASRN: | 105-87-3 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 125080_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 01/08/1990 | Bone Marrow | 42 | Male | Mouse | B6C3F1 | IP/IJ x 1, 42 hour | Negative |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
10675 | 25 | 6.97 | ± | 0.680 |
| 10676 | 25 | 3.80 | ± | 0.361 | |||
| 10677 | 25 | 3.04 | ± | 0.453 | |||
| 10678 | 25 | 5.49 | ± | 0.546 | |||
| Average | 4.83 | ± | 0.879 | ||||
| Test Chemical | Geranyl acetate |
425 |
10645 | 25 | 8.36 | ± | 0.941 |
| 10646 | 25 | 5.32 | ± | 0.660 | |||
| 10647 | 25 | 4.21 | ± | 0.373 | |||
| 10648 | 25 | 7.84 | ± | 0.843 | |||
| Average | 6.43 | ± | 0.996 | ||||
| Test Chemical | Geranyl acetate |
850 |
10650 | 25 | 3.40 | ± | 0.412 |
| 10651 | 25 | 5.78 | ± | 0.540 | |||
| 10652 | 25 | 7.68 | ± | 0.745 | |||
| 10653 | 25 | 3.52 | ± | 0.514 | |||
| Average | 5.10 | ± | 1.021 | ||||
| Test Chemical | Geranyl acetate |
1700 |
10655 | 25 | 5.11 | ± | 0.606 |
| 10656 | 25 | 4.50 | ± | 0.479 | |||
| 10657 | 25 | 5.57 | ± | 0.535 | |||
| 10658 | 25 | 4.28 | ± | 0.414 | |||
| Average | 4.86 | ± | 0.293 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
10680 | 25 | 7.26 | ± | 0.898 |
| 10681 | 25 | 10.82 | ± | 0.768 | |||
| 10682 | 25 | 12.15 | ± | 0.985 | |||
| 10683 | 25 | 9.49 | ± | 0.640 | |||
| Average | 9.92 | ± | 1.043 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed