| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02196-0020-0000-2 |
| Chemical Name: | Furfuryl alcohol |
| CASRN: | 98-00-0 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 150910_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 11/17/1986 | Bone Marrow | 23 | Male | Mouse | B6C3F1 | IP/IJ x 1, 23 hour | Negative |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
4578 | 25 | 3.33 | ± | 0.383 |
| 4579 | 25 | 5.10 | ± | 0.733 | |||
| 4580 | 25 | 4.96 | ± | 0.562 | |||
| 4581 | 25 | 4.50 | ± | 0.547 | |||
| Average | 4.47 | ± | 0.401 | ||||
| Test Chemical | Furfuryl alcohol |
75 |
4558 | 25 | 6.33 | ± | 0.523 |
| 4559 | 25 | 3.33 | ± | 0.361 | |||
| 4560 | 25 | 3.57 | ± | 0.497 | |||
| 4561 | 25 | 3.36 | ± | 0.389 | |||
| Average | 4.15 | ± | 0.730 | ||||
| Test Chemical | Furfuryl alcohol |
150 |
4563 | 25 | 5.14 | ± | 0.581 |
| 4564 | 25 | 7.03 | ± | 0.754 | |||
| 4565 | 25 | 5.86 | ± | 0.523 | |||
| 4566 | 25 | 4.78 | ± | 0.487 | |||
| Average | 5.70 | ± | 0.496 | ||||
| Test Chemical | Furfuryl alcohol |
300 |
4568 | 25 | 2.52 | ± | 0.277 |
| 4569 | 25 | 7.46 | ± | 0.932 | |||
| 4570 | 25 | 4.31 | ± | 0.365 | |||
| 4571 | 25 | 4.22 | ± | 0.430 | |||
| Average | 4.63 | ± | 1.030 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
4573 | 25 | 8.86 | ± | 0.827 |
| 4574 | 25 | 9.26 | ± | 0.829 | |||
| 4575 | 25 | 9.18 | ± | 0.932 | |||
| 4576 | 25 | 9.31 | ± | 1.051 | |||
| Average | 9.15 | ± | 0.101 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed