| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02196-0020-0000-2 |
| Chemical Name: | Furfuryl alcohol |
| CASRN: | 98-00-0 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 150910_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 04/25/1988 | Bone Marrow | 42 | Male | Mouse | B6C3F1 | IP/IJ x 1, 42 hour | Negative |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
7814 | 25 | 4.94 | ± | 0.375 |
| 7815 | 25 | 5.09 | ± | 0.468 | |||
| 7816 | 25 | 9.31 | ± | 0.864 | |||
| 7817 | 25 | 5.22 | ± | 0.536 | |||
| Average | 6.14 | ± | 1.059 | ||||
| Test Chemical | Furfuryl alcohol |
37.5 |
7799 | 25 | 6.36 | ± | 0.510 |
| 7800 | 25 | 6.25 | ± | 0.740 | |||
| 7801 | 25 | 4.45 | ± | 0.553 | |||
| 7802 | 25 | 5.88 | ± | 0.589 | |||
| Average | 5.74 | ± | 0.441 | ||||
| Test Chemical | Furfuryl alcohol |
75 |
7804 | 25 | 7.01 | ± | 0.842 |
| 7805 | 25 | 4.53 | ± | 0.328 | |||
| 7806 | 25 | 9.38 | ± | 0.930 | |||
| 7807 | 25 | 6.34 | ± | 0.557 | |||
| Average | 6.82 | ± | 1.002 | ||||
| Test Chemical | Furfuryl alcohol |
150 |
7809 | 25 | 5.57 | ± | 0.442 |
| 7810 | 25 | 5.68 | ± | 0.568 | |||
| 7811 | 25 | 7.21 | ± | 0.839 | |||
| 7812 | 25 | 3.13 | ± | 0.338 | |||
| Average | 5.40 | ± | 0.844 | ||||
| Positive Control | Dimethylbenzanthracene |
100 |
7819 | 25 | 21.51 | ± | 1.928 |
| 7820 | 25 | 17.69 | ± | 1.249 | |||
| 7821 | 25 | 16.43 | ± | 1.042 | |||
| 7822 | 25 | 17.94 | ± | 1.707 | |||
| Average | 18.41 | ± | 1.091 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed