| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02934-0017-0000-8 |
| Chemical Name: | Tribromomethane |
| CASRN: | 75-25-2 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 244282_SCE |
| Study Result: | Positive |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 03/16/1987 | Bone Marrow | 36 | Male | Mouse | B6C3F1 | IP/IJ x 1, 36 hour | Positive |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
4851 | 25 | 3.89 | ± | 0.364 |
| 4857 | 24 | 3.34 | ± | 0.322 | |||
| 4868 | 25 | 6.00 | ± | 0.605 | |||
| 4871 | 25 | 4.94 | ± | 0.359 | |||
| Average | 4.55 | ± | 0.587 | ||||
| Test Chemical | Tribromomethane |
800 |
4846 | 25 | 7.19 | ± | 0.464 |
| 4850 | 25 | 6.06 | ± | 0.516 | |||
| 4865 | 25 | 4.48 | ± | 0.377 | |||
| 4866 | 25 | 7.00 | ± | 0.429 | |||
| Average | 6.18 | ± | 0.620 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
4855 | 25 | 8.23 | ± | 0.458 |
| 4861 | 25 | 6.74 | ± | 0.704 | |||
| 4863 | 25 | 7.97 | ± | 0.731 | |||
| 4867 | 25 | 9.73 | ± | 0.854 | |||
| Average | 8.16 | ± | 0.615 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed