| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01750-0019-0000-5 |
| Chemical Name: | Butyl benzyl phthalate |
| CASRN: | 85-68-7 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 336452_SCE |
| Study Result: | Positive |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 08/11/1987 | Bone Marrow | 42 | Male | Mouse | B6C3F1 | IP/IJ x 1, 42 hour | Positive |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
5898 | 25 | 5.16 | ± | 0.696 |
| 5913 | 24 | 4.29 | ± | 0.458 | |||
| 5921 | 25 | 4.58 | ± | 0.397 | |||
| 5942 | 23 | 5.11 | ± | 0.509 | |||
| Average | 4.79 | ± | 0.211 | ||||
| Test Chemical | Butyl benzyl phthalate |
1250 |
5896 | 25 | 5.89 | ± | 0.572 |
| 5900 | 25 | 6.19 | ± | 0.454 | |||
| 5923 | 25 | 5.25 | ± | 0.472 | |||
| 5935 | 25 | 5.66 | ± | 0.458 | |||
| Average | 5.73 | ± | 0.198 | ||||
| Test Chemical | Butyl benzyl phthalate |
2500 |
5904 | 25 | 3.82 | ± | 0.527 |
| 5925 | 25 | 5.01 | ± | 0.427 | |||
| 5928 | 25 | 4.63 | ± | 0.386 | |||
| 5929 | 25 | 4.79 | ± | 0.451 | |||
| Average | 4.56 | ± | 0.259 | ||||
| Test Chemical | Butyl benzyl phthalate |
5000 |
5915 | 25 | 5.59 | ± | 0.540 |
| 5917 | 25 | 6.57 | ± | 0.453 | |||
| 5931 | 25 | 5.97 | ± | 0.415 | |||
| 5936 | 25 | 5.83 | ± | 0.482 | |||
| Average | 5.99 | ± | 0.207 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed