| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01712-0021-0000-6 |
| Chemical Name: | Benzyl acetate |
| CASRN: | 140-11-4 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 500814_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 12/10/1990 | Bone Marrow | 42 | Male | Mouse | B6C3F1 | IP/IJ x 1, 42 hour | Negative |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
11410 | 25 | 2.79 | ± | 0.367 |
| 11411 | 25 | 6.40 | ± | 0.704 | |||
| 11412 | 25 | 3.94 | ± | 0.481 | |||
| 11413 | 25 | 5.44 | ± | 0.532 | |||
| Average | 4.65 | ± | 0.799 | ||||
| Test Chemical | Benzyl acetate |
325 |
11395 | 25 | 4.69 | ± | 0.406 |
| 11396 | 25 | 5.81 | ± | 0.606 | |||
| 11397 | 25 | 3.30 | ± | 0.259 | |||
| 11398 | 25 | 2.65 | ± | 0.288 | |||
| Average | 4.10 | ± | 0.709 | ||||
| Test Chemical | Benzyl acetate |
650 |
11400 | 25 | 7.94 | ± | 0.554 |
| 11401 | 25 | 2.81 | ± | 0.332 | |||
| 11402 | 25 | 10.55 | ± | 1.150 | |||
| 11403 | 25 | 5.05 | ± | 0.426 | |||
| Average | 6.59 | ± | 1.687 | ||||
| Test Chemical | Benzyl acetate |
1300 |
11405 | 25 | 4.06 | ± | 0.417 |
| 11406 | 25 | 4.96 | ± | 0.584 | |||
| 11407 | 25 | 4.73 | ± | 0.491 | |||
| 11408 | 25 | 2.80 | ± | 0.311 | |||
| Average | 4.14 | ± | 0.484 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
11415 | 25 | 9.41 | ± | 0.711 |
| 11416 | 25 | 10.13 | ± | 0.837 | |||
| 11417 | 25 | 7.78 | ± | 0.824 | |||
| 11418 | 25 | 7.13 | ± | 0.729 | |||
| Average | 8.61 | ± | 0.696 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed