| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01712-0021-0000-6 |
| Chemical Name: | Benzyl acetate |
| CASRN: | 140-11-4 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 500814_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 02/18/1987 | Bone Marrow | 23 | Male | Mouse | B6C3F1 | IP/IJ x 1, 23 hour | Negative |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
5085 | 25 | 5.46 | ± | 0.497 |
| 5086 | 25 | 3.76 | ± | 0.322 | |||
| 5087 | 25 | 3.68 | ± | 0.577 | |||
| 5088 | 25 | 3.16 | ± | 0.407 | |||
| Average | 4.02 | ± | 0.499 | ||||
| Test Chemical | Benzyl acetate |
425 |
5055 | 25 | 6.01 | ± | 0.785 |
| 5056 | 25 | 2.44 | ± | 0.432 | |||
| 5057 | 25 | 3.25 | ± | 0.381 | |||
| 5058 | 25 | 3.85 | ± | 0.394 | |||
| Average | 3.89 | ± | 0.763 | ||||
| Test Chemical | Benzyl acetate |
850 |
5060 | 25 | 8.03 | ± | 1.358 |
| 5061 | 25 | 2.80 | ± | 0.258 | |||
| 5062 | 25 | 3.44 | ± | 0.405 | |||
| 5063 | 25 | 4.25 | ± | 0.438 | |||
| Average | 4.64 | ± | 1.171 | ||||
| Test Chemical | Benzyl acetate |
1700 |
5065 | 25 | 3.63 | ± | 0.384 |
| 5066 | 25 | 4.27 | ± | 0.530 | |||
| 5067 | 25 | 4.13 | ± | 0.531 | |||
| Average | 4.01 | ± | 0.194 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
5090 | 25 | 5.22 | ± | 0.490 |
| 5091 | 25 | 7.03 | ± | 0.764 | |||
| 5092 | 25 | 5.74 | ± | 0.662 | |||
| 5093 | 25 | 5.29 | ± | 0.559 | |||
| Average | 5.81 | ± | 0.420 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed