| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02013-0014-0000-3 |
| Chemical Name: | Dichlorvos |
| CASRN: | 62-73-7 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 755734_SCE |
| Study Result: | Negative |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 07/14/1983 | Bone Marrow | 17 | Male | Mouse | B6C3F1 | IP/IJ x 1, 17 hour | Not a Valid Test |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Phosphate Buffered Saline |
0 |
651 | 25 | 3.32 | ± | 0.280 |
| 654 | 25 | 3.70 | ± | 0.319 | |||
| 675 | 25 | 5.72 | ± | 0.415 | |||
| 676 | 25 | 4.49 | ± | 0.247 | |||
| Average | 4.31 | ± | 0.530 | ||||
| Test Chemical | Dichlorvos |
6.25 |
652 | 25 | 2.68 | ± | 0.154 |
| 661 | 25 | 4.25 | ± | 0.337 | |||
| 666 | 25 | 6.45 | ± | 0.431 | |||
| 674 | 25 | 4.22 | ± | 0.352 | |||
| Average | 4.39 | ± | 0.774 | ||||
| Test Chemical | Dichlorvos |
12.5 |
663 | 25 | 3.94 | ± | 0.351 |
| 664 | 25 | 4.40 | ± | 0.325 | |||
| 670 | 25 | 5.50 | ± | 0.657 | |||
| 678 | 25 | 6.99 | ± | 0.578 | |||
| Average | 5.21 | ± | 0.678 | ||||
| Test Chemical | Dichlorvos |
25 |
653 | 24 | 3.32 | ± | 0.339 |
| 656 | 24 | 3.42 | ± | 0.247 | |||
| 677 | 25 | 4.80 | ± | 0.429 | |||
| 679 | 25 | 3.81 | ± | 0.356 | |||
| Average | 3.85 | ± | 0.339 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed