| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02806-0006-0000-4 |
| Chemical Name: | Sodium (2-ethylhexyl)alcohol sulfate |
| CASRN: | 126-92-1 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 795640_SCE |
| Study Result: | Positive |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 05/05/1987 | Bone Marrow | 23 | Male | Mouse | B6C3F1 | IP/IJ x 1, 23 hour | No Call |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Phosphate Buffered Saline |
0 |
5422 | 25 | 4.31 | ± | 0.511 |
| 5423 | 25 | 2.72 | ± | 0.378 | |||
| 5424 | 25 | 2.68 | ± | 0.330 | |||
| 5425 | 25 | 4.77 | ± | 0.544 | |||
| Average | 3.62 | ± | 0.539 | ||||
| Test Chemical | Sodium (2-ethylhexyl)alcohol sulfate |
275 |
5407 | 25 | 4.97 | ± | 0.762 |
| 5408 | 25 | 4.14 | ± | 0.360 | |||
| 5409 | 25 | 3.69 | ± | 0.486 | |||
| 5410 | 25 | 4.74 | ± | 0.538 | |||
| Average | 4.39 | ± | 0.292 | ||||
| Test Chemical | Sodium (2-ethylhexyl)alcohol sulfate |
550 |
5412 | 25 | 5.16 | ± | 0.528 |
| 5413 | 25 | 6.24 | ± | 0.676 | |||
| 5414 | 25 | 4.46 | ± | 0.587 | |||
| 5415 | 25 | 4.09 | ± | 0.414 | |||
| Average | 4.99 | ± | 0.473 | ||||
| Test Chemical | Sodium (2-ethylhexyl)alcohol sulfate |
1100 |
5417 | 25 | 6.35 | ± | 0.715 |
| 5418 | 25 | 4.84 | ± | 0.652 | |||
| 5419 | 25 | 6.49 | ± | 0.476 | |||
| 5420 | 25 | 7.45 | ± | 0.825 | |||
| Average | 6.29 | ± | 0.539 | ||||
| Positive Control | Mitomycin-C |
0.5 |
5427 | 25 | 9.62 | ± | 0.918 |
| 5428 | 25 | 10.99 | ± | 0.717 | |||
| 5429 | 25 | 4.37 | ± | 0.510 | |||
| 5430 | 25 | 8.14 | ± | 0.655 | |||
| Average | 8.28 | ± | 1.426 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed