| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02806-0006-0000-4 |
| Chemical Name: | Sodium (2-ethylhexyl)alcohol sulfate |
| CASRN: | 126-92-1 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 795640_SCE |
| Study Result: | Positive |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 08/01/1988 | Bone Marrow | 23 | Male | Mouse | B6C3F1 | IP/IJ x 1, 23 hour | No Call |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Phosphate Buffered Saline |
0 |
8558 | 25 | 2.96 | ± | 0.313 |
| 8559 | 25 | 5.54 | ± | 0.640 | |||
| 8560 | 25 | 4.76 | ± | 0.661 | |||
| 8561 | 25 | 3.72 | ± | 0.402 | |||
| Average | 4.25 | ± | 0.568 | ||||
| Test Chemical | Sodium (2-ethylhexyl)alcohol sulfate |
825 |
8538 | 25 | 9.21 | ± | 0.829 |
| 8539 | 25 | 4.57 | ± | 0.473 | |||
| 8540 | 25 | 7.34 | ± | 0.578 | |||
| 8542 | 25 | 8.52 | ± | 0.954 | |||
| Average | 7.41 | ± | 1.022 | ||||
| Test Chemical | Sodium (2-ethylhexyl)alcohol sulfate |
1100 |
8543 | 25 | 7.53 | ± | 1.031 |
| 8544 | 25 | 11.76 | ± | 0.888 | |||
| 8545 | 25 | 6.00 | ± | 0.500 | |||
| 8546 | 25 | 5.77 | ± | 0.674 | |||
| Average | 7.77 | ± | 1.388 | ||||
| Positive Control | Mitomycin-C |
1 |
8563 | 25 | 6.76 | ± | 0.698 |
| 8564 | 25 | 7.06 | ± | 0.579 | |||
| 8565 | 25 | 6.92 | ± | 0.624 | |||
| 8566 | 25 | 6.28 | ± | 0.430 | |||
| Average | 6.76 | ± | 0.169 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed