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Study Information
Study Attribute Value
CEBS Accession Number: 002-02044-0017-0000-0
Chemical Name: Diglycidyl resorcinol ether (DGRE)
CASRN: 101-90-6
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 873378_SCE
Study Result: Positive


Table Instructions and Notes:

Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.


Detailed Sister Chromatid Exchange Data (Trial 2)
Initial Treatment Date Tissue Sample Time (h) Sex Species Strain Protocol Trial Result
07/15/1987 Bone Marrow 42 Male Mouse B6C3F1 IP/IJ x 1,  42 hour Positive

Test Group Dose
(mg/kg)		 Animal
Number		 No.
Cells		 SCE / Cell
Mean ± SEM
Vehicle Control Corn Oil 
 0         
 5675 24 3.02 ± 0.314
    5688 25 3.69 ± 0.352
    5695 25 3.67 ± 0.407
    5698 25 5.22 ± 0.396
Average   3.91 ± 0.465
 
Test Chemical Diglycidyl resorcinol ether (DGRE) 
125         
 5667 24 4.38 ± 0.461
    5681 25 4.93 ± 0.578
    5685 25 4.53 ± 0.458
    5694 24 3.61 ± 0.405
Average   4.38 ± 0.278
 
Test Chemical Diglycidyl resorcinol ether (DGRE) 
250         
 5665 25 4.20 ± 0.348
    5666 25 3.83 ± 0.454
    5678 25 4.27 ± 0.359
    5696 25 4.19 ± 0.492
Average   4.12 ± 0.099
 
Test Chemical Diglycidyl resorcinol ether (DGRE) 
500         
 5668 25 3.13 ± 0.349
    5680 24 4.14 ± 0.459
    5683 25 4.27 ± 0.361
    5693 24 3.70 ± 0.405
Average   3.81 ± 0.255
 
Positive Control Dimethylbenzanthracene 
2.5       
 5664 25 10.70 ± 0.832
    5669 25 10.79 ± 0.843
    5672 25 7.62 ± 0.856
    5679 25 6.53 ± 0.718
Average   8.92 ± 1.084
 

Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed