| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02044-0017-0000-0 |
| Chemical Name: | Diglycidyl resorcinol ether (DGRE) |
| CASRN: | 101-90-6 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 873378_SCE |
| Study Result: | Positive |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 04/21/1988 | Bone Marrow | 23 | Male | Mouse | B6C3F1 | IP/IJ x 1, 23 hour | Positive |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
8268 | 24 | 4.30 | ± | 0.421 |
| 8284 | 24 | 4.35 | ± | 0.424 | |||
| 8297 | 25 | 6.06 | ± | 0.498 | |||
| 8303 | 24 | 5.67 | ± | 0.630 | |||
| 8308 | 25 | 4.88 | ± | 0.466 | |||
| Average | 5.06 | ± | 0.352 | ||||
| Test Chemical | Diglycidyl resorcinol ether (DGRE) |
500 |
8298 | 25 | 6.90 | ± | 0.479 |
| 8304 | 25 | 6.27 | ± | 0.672 | |||
| 8306 | 24 | 6.04 | ± | 0.522 | |||
| 8310 | 25 | 11.12 | ± | 0.933 | |||
| Average | 7.60 | ± | 1.194 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
8273 | 25 | 8.31 | ± | 0.841 |
| 8276 | 25 | 9.01 | ± | 0.791 | |||
| 8294 | 25 | 7.52 | ± | 0.688 | |||
| 8301 | 25 | 11.16 | ± | 0.686 | |||
| Average | 9.01 | ± | 0.782 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed