| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-02013-0016-0000-5 |
| Chemical Name: | Dichlorvos |
| CASRN: | 62-73-7 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 918411_SCE |
| Study Result: | Negative (Nonstandard Protocol) |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 05/04/1983 | Bone Marrow | 23 | Male | Mouse | B6C3F1 | IP/IJ x 1, 23 hour | Not a Valid Test |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
975 | 25 | 3.76 | ± | 0.315 |
| 976 | 25 | 3.94 | ± | 0.451 | |||
| 977 | 25 | 4.65 | ± | 0.602 | |||
| 978 | 25 | 6.13 | ± | 0.672 | |||
| Average | 4.62 | ± | 0.539 | ||||
| Test Chemical | Dichlorvos |
10 |
980 | 25 | 5.08 | ± | 0.495 |
| 981 | 25 | 4.24 | ± | 0.446 | |||
| 982 | 25 | 5.24 | ± | 0.521 | |||
| 983 | 25 | 4.60 | ± | 0.409 | |||
| Average | 4.79 | ± | 0.228 | ||||
| Test Chemical | Dichlorvos |
20 |
985 | 25 | 4.78 | ± | 0.521 |
| 986 | 25 | 4.90 | ± | 0.708 | |||
| 987 | 25 | 4.47 | ± | 0.539 | |||
| 988 | 25 | 5.47 | ± | 0.569 | |||
| Average | 4.90 | ± | 0.208 | ||||
| Test Chemical | Dichlorvos |
40 |
913 | 25 | 4.77 | ± | 0.401 |
| 914 | 25 | 4.20 | ± | 0.465 | |||
| 990 | 25 | 4.70 | ± | 0.591 | |||
| 991 | 25 | 4.54 | ± | 0.539 | |||
| Average | 4.56 | ± | 0.126 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed