| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01984-0013-0000-8 |
| Chemical Name: | Diallyl phthalate |
| CASRN: | 131-17-9 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 993263_SCE |
| Study Result: | Positive |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 12/10/1987 | Bone Marrow | 23 | Male | Mouse | B6C3F1 | IP/IJ x 1, 23 hour |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
7025 | 25 | 4.56 | ± | 0.710 |
| 7026 | 25 | 5.44 | ± | 0.531 | |||
| 7027 | 25 | 4.30 | ± | 0.567 | |||
| 7028 | 25 | 2.72 | ± | 0.406 | |||
| Average | 4.25 | ± | 0.567 | ||||
| Test Chemical | Diallyl phthalate |
75 |
6995 | 25 | 4.16 | ± | 0.610 |
| 6996 | 25 | 3.95 | ± | 0.407 | |||
| 6997 | 25 | 6.61 | ± | 0.891 | |||
| 6998 | 25 | 4.49 | ± | 0.487 | |||
| Average | 4.80 | ± | 0.613 | ||||
| Test Chemical | Diallyl phthalate |
150 |
7000 | 25 | 5.60 | ± | 0.709 |
| 7001 | 25 | 4.90 | ± | 0.524 | |||
| 7002 | 25 | 5.42 | ± | 0.606 | |||
| 7003 | 25 | 6.09 | ± | 0.729 | |||
| Average | 5.51 | ± | 0.246 | ||||
| Test Chemical | Diallyl phthalate |
300 |
7005 | 25 | 7.13 | ± | 0.504 |
| 7006 | 25 | 5.76 | ± | 0.564 | |||
| 7007 | 25 | 6.55 | ± | 0.615 | |||
| 7008 | 25 | 8.82 | ± | 0.776 | |||
| Average | 7.06 | ± | 0.649 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
7030 | 25 | 10.14 | ± | 1.123 |
| 7031 | 25 | 6.14 | ± | 0.593 | |||
| 7032 | 25 | 11.19 | ± | 1.174 | |||
| 7033 | 25 | 7.67 | ± | 0.791 | |||
| Average | 8.81 | ± | 1.149 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed