| Study Attribute | Value |
|---|---|
| CEBS Accession Number: | 002-01984-0013-0000-8 |
| Chemical Name: | Diallyl phthalate |
| CASRN: | 131-17-9 |
| NTP Study Type: | Genetic Toxicology - Rodent Cytogenetics |
| NTP Study ID: | 993263_SCE |
| Study Result: | Positive |
Table Instructions and Notes:
Below are the detailed Sister Chromatid Exchange data. You may also view the summary data for this study.
| Initial Treatment Date | Tissue | Sample Time (h) | Sex | Species | Strain | Protocol | Trial Result |
|---|---|---|---|---|---|---|---|
| 07/06/1988 | Bone Marrow | 23 | Male | Mouse | B6C3F1 | IP/IJ x 1, 23 hour |
| Test Group | Dose (mg/kg) |
Animal Number |
No. Cells |
SCE / Cell | |||
|---|---|---|---|---|---|---|---|
| Mean | ± | SEM | |||||
| Vehicle Control | Corn Oil |
0 |
8253 | 25 | 4.68 | ± | 0.519 |
| 8254 | 25 | 4.36 | ± | 0.648 | |||
| 8255 | 25 | 4.41 | ± | 0.503 | |||
| 8256 | 25 | 4.53 | ± | 0.530 | |||
| Average | 4.50 | ± | 0.071 | ||||
| Test Chemical | Diallyl phthalate |
225 |
8243 | 25 | 10.00 | ± | 0.926 |
| 8244 | 25 | 4.04 | ± | 0.411 | |||
| 8245 | 25 | 6.25 | ± | 0.563 | |||
| 8246 | 25 | 8.32 | ± | 0.934 | |||
| Average | 7.14 | ± | 1.289 | ||||
| Test Chemical | Diallyl phthalate |
300 |
8248 | 25 | 7.32 | ± | 0.625 |
| 8249 | 25 | 8.77 | ± | 0.970 | |||
| 8250 | 25 | 6.02 | ± | 0.740 | |||
| Average | 7.36 | ± | 0.793 | ||||
| Positive Control | Dimethylbenzanthracene |
2.5 |
8258 | 25 | 6.42 | ± | 0.779 |
| 8259 | 25 | 8.46 | ± | 0.646 | |||
| 8260 | 25 | 6.58 | ± | 0.615 | |||
| 8261 | 25 | 6.93 | ± | 1.085 | |||
| Average | 7.10 | ± | 0.466 | ||||
Footnotes:
IP/IJ: Intraperitoneal Injection
n: Number of animals analyzed
n: Number of animals analyzed