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Long-Term Study Body Weights

Study Information:

Chemical Name: Coumarin
CASRN: ="91-64-5"
Study Number: C07103B
Exposure Route: GAVAGE
TDMS Number: 0509001
Sex: Male
Strain and Species: F 344/N Rats

Table Instructions and Notes:
Multiple body weights in a single week are displayed in one cell separated by "|". Values displayed may not match report summary values due to individual values being excluded in some cases.
Animal Number Cage Number Dose Group Days On Study Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 18 Week 21 Week 25 Week 29 Week 31 Week 33 Week 37 Week 38 Week 40 Week 41 Week 44 Week 45 Week 48 Week 49 Week 51 Week 53 Week 54 Week 55 Week 57 Week 58 Week 59 Week 60 Week 61 Week 62 Week 65 Week 66 Week 68 Week 69 Week 70 Week 71 Week 72 Week 73 Week 74 Week 75 Week 76 Week 77 Week 78 Week 79 Week 80 Week 81 Week 82 Week 83 Week 84 Week 85 Week 86 Week 87 Week 88 Week 89 Week 90 Week 91 Week 92 Week 93 Week 94 Week 95 Week 96 Week 97 Week 98 Week 99 Week 100 Week 101 Week 103 Week 104 Week 105 Removal Reason
1 1 Vehicle Control 420 176.4 212.7 240.2 269.5 277.9 288.4 308 322.8 336 346.6 354.2 366.8 368.6 393.7 410.5 438.2 445.5 469 473.5 478.1 491.4 499.6 495.1 422.7 331.5 Moribund
2 1 Vehicle Control 729 196.5 222.2 254.8 275.3 292.8 303.5 322.9 335.9 348.5 356.8 362.6 378 382 398.1 412.4 440.6 445 465.6 469.1 481.8 491.8 501.1 502 506.4 508.7 512.6 522.9 515.3 510.3 527 514.4 507.3 501.3 463.3 458.8 453.9 452.5 Terminal Sacrifice
3 1 Vehicle Control 729 197.7 222.3 246.4 264.6 276.5 308.8 302.4 316.7 329.7 343.5 346.6 360 362 387.7 404.8 416.2 414 430.4 430.9 438.5 452.7 457.2 464.7 474.6 483.2 485.7 485 483.5 482 495.6 481.6 476.4 479.8 474 470.3 468.3 464.2 Terminal Sacrifice
4 1 Vehicle Control 455 180.5 213.2 246.3 267 288.5 302.6 329 339.4 353.5 361.9 374.2 383.6 389.5 421.2 430.1 450.6 466.1 499.3 509.7 520.9 535.4 550.8 551.5 563.1 569.4 577.8 Interval Sacrifice
6 2 Vehicle Control 730 173.2 208.6 246.6 276.3 296.5 316.5 329.7 344.2 358.6 371.2 372.6 392.4 392.5 417.6 430.6 447.5 456 487.6 480.4 498 515.8 517.8 530.7 547.4 555.8 570.4 574.5 575.9 574.5 587 560 559.8 560.9 543.7 559.6 551.8 529.7 Terminal Sacrifice
7 2 Vehicle Control 729 179.1 212.6 238.2 258.3 275.9 291.6 305.3 318 332.2 342.2 348.5 358.1 359.1 386.7 395.9 408.3 425.1 451.2 460.1 475.9 484.4 489.3 496.6 512.7 515.2 515.7 511.5 507 501.4 505.8 485.1 485.9 482.8 472.8 477.4 473.7 472.4 Terminal Sacrifice
8 2 Vehicle Control 456 186.3 220.9 249.1 270 289.3 307.7 319.7 332.2 344.7 356.2 359.9 372.8 376.8 389.7 418.6 431.6 440.2 464.9 468.2 489.1 503.5 500.1 505.8 514.7 515.4 518.2 518.6 Interval Sacrifice
9 2 Vehicle Control 729 196.7 219.8 247 270.2 284.6 306.8 319.6 333.1 344.2 355 361 374.2 379.4 407.5 424 439.4 445.3 476.6 472.3 485.8 493.8 500.2 512.7 528.1 535.4 541 544.7 549.1 547.6 557.3 525.9 517.5 498.8 472.1 455.1 450.9 446 Terminal Sacrifice
10 2 Vehicle Control 729 211.1 229.1 260.6 272.8 296.1 313.2 324.7 335.7 348.4 357.5 363 380.7 382.1 407.5 416.8 422 429.5 459.6 455.6 471.8 479.9 482.3 490.6 503.2 495 487.4 484.8 477.7 475.4 473 462.8 467 466.7 443.9 430.7 426.8 420.7 Terminal Sacrifice
11 3 Vehicle Control 660 189.2 222.9 247.6 270.6 290.1 303.8 315.5 327.4 337.1 348.3 356.7 362.7 371.6 393 404.9 423.1 438.8 460.8 464.1 476.2 461.5 485.5 488.6 495.8 513 515.3 514.2 521.7 524.3 545.1 528.3 564.8 575.1 582.5 Moribund
12 3 Vehicle Control 586 161.7 193.9 223.6 251 267.5 283.6 294.9 307.7 316 330.7 335.9 347.1 351 375.5 391.5 407.6 423.2 434.1 441.3 448.2 447.2 459.2 466 476.7 485.2 494.8 508 503.5 501.2 485.3 323.7 Moribund
13 3 Vehicle Control 729 165.6 202.7 228.7 248.7 268 286.5 296.7 310.4 316.5 327.8 337.1 350.1 357 377.6 384.8 400.3 408.9 428.2 434.8 449 448.6 470 467.6 476.1 484.6 493.4 490.7 490.2 488.9 485.1 465.1 460.3 461.2 448.2 438.3 437 422.7 Terminal Sacrifice
14 3 Vehicle Control 694 174.4 200.1 237.7 255.7 271.7 291.1 302.2 318.8 325.4 340.2 346.1 361.2 366.4 393.7 410.5 426.5 447.2 466.3 470.6 482.8 479.7 481.8 490.9 503.3 508.2 513.8 518.1 508.1 501.5 489.4 471.7 479.1 482.3 449.8 433.4 Moribund
15 3 Vehicle Control 609 183 209.7 251.3 261.4 287 302.2 318.9 333.3 339.8 350.4 357.8 374.6 376.9 401.5 416.8 443.6 458.4 484.1 487.5 509.7 491 521.2 523.5 524.3 533.6 545.9 546.7 539.5 540.6 536.2 570.4 581.1 Moribund
16 4 Vehicle Control 729 193.5 228.2 257.4 273.2 296.4 313.9 309.3 327.8 345.2 357.7 363 365 374.8 388.9 397.3 424.9 442.3 465 472.1 486.4 495.7 506.9 521.9 525.7 539.3 536.2 540.5 559.4 556.1 542.8 532.2 530.3 521.2 507.2 515.9 516.2 509.5 Terminal Sacrifice
17 4 Vehicle Control 729 192 227.6 265.2 279.4 303.2 319 324.7 328.9 343.8 355 357.1 369.7 374.7 393.9 399.2 424.1 429.1 452.1 457.6 472 468.1 474.2 492.7 497.1 505.3 501.6 497 491.9 488.1 483 479.3 478 480.3 467.1 461.4 450.4 441 Terminal Sacrifice
18 4 Vehicle Control 730 170.2 207.9 241.5 270.6 288.2 306.5 320.8 334.8 348.5 356.3 367 381.4 386.4 405.6 425.8 446.8 464.9 476.7 475.4 498.7 497.5 506.6 514.9 522.9 535.1 535.5 532.7 538.7 537 527.1 521.9 513.1 512 509 505.6 500.1 460.1 Terminal Sacrifice
19 4 Vehicle Control 453 171.5 202.2 236 248.4 267 279.8 287 289.5 298.4 312.3 319.4 330.6 338.3 360.2 366.4 396.9 403 423.6 428.1 441.1 433.3 444.6 451.8 454.5 458.7 432.6 Interval Sacrifice
20 4 Vehicle Control 729 199.5 232.6 268.2 284.4 305.7 320.4 327.6 337.8 354.1 367.6 376.1 385.7 392.4 403.7 426.7 456.2 477.1 498.2 506.2 504.5 503.9 518.4 532.4 537.8 549.1 555.1 560.4 561.7 558.6 558.5 553 555.8 554.3 547.4 545 544.4 526.1 Terminal Sacrifice
21 5 Vehicle Control 730 171.5 203.2 229.2 248.6 267.3 278.8 289.4 296 311.8 310.3 321.9 332.6 336.8 361.6 365.1 386.6 405.5 416.1 425.7 439 442.6 452.4 451.6 449.3 445.4 450.1 450.7 434.4 445.4 432.4 425.9 418.7 403.3 403.1 398 394.7 Terminal Sacrifice
22 5 Vehicle Control 513 197.5 230.6 262.9 276 298.4 313.3 321.1 326.3 345.9 356.4 365.9 375.3 378.1 401.6 411.3 432.2 443.9 453.7 466.6 475.6 477.1 494 490.4 507.5 515.9 512.1 506.3 497 474.8 Moribund
23 5 Vehicle Control 729 168.1 189.4 217.3 235 262.1 275.3 281.3 292.6 306.4 317.8 326 334.4 339.3 357.6 367.7 387.6 409 420.3 438.8 451.7 455.6 466.4 468.9 480.8 495.7 496.1 493.4 496.3 494.2 493.4 448.3 440.4 412.7 421.6 426.9 417.1 422 Terminal Sacrifice
24 5 Vehicle Control 729 192.1 224.8 260.6 284.9 298.6 315 325.9 331.3 351.3 363.2 369.6 384.7 390.5 414.3 423.4 459.7 474 483.1 503.2 518.3 524.7 540.6 543.6 553.8 562.7 554.5 562.9 562.8 553.8 549.8 539.6 525.2 518.7 499.3 479.3 467.4 460.2 Terminal Sacrifice
25 5 Vehicle Control 455 194.2 222.3 247 269.3 287.7 302.9 307.7 317.5 335.8 351.9 361.1 374.3 381.9 401 416.5 429 448.8 471.7 486.2 499.1 508.9 516.9 527.3 534.2 548.2 558.6 Interval Sacrifice
26 6 Vehicle Control 730 193.6 224.7 264.9 276.5 307.7 325.2 331.2 338.4 361.8 371.7 376.3 395.8 399.5 414.9 428.7 450.1 449.1 482.8 487.9 493.9 507 517.6 522.9 535.7 528.4 529.7 523.4 535.7 527.7 534.4 531.4 526 519.7 489.9 487 469.1 440.2 Terminal Sacrifice
27 6 Vehicle Control 623 192 222.2 254.2 280.8 307.4 321.9 336.1 345.3 363.7 372.9 377.2 389.4 401.7 420.2 447.5 473.5 467 496.2 502 513.4 506.6 517 525.4 528.8 527.4 523.7 524.8 532.7 529.3 536.7 525.1 276.3 Dead
28 6 Vehicle Control 704 214.9 240.9 276.4 293.7 311.6 327.9 338.1 345.1 363.4 375.2 382.7 396 400.1 414.8 429.3 451.8 444.2 487.7 497.4 501.8 510 520.8 523.4 534.2 550.3 548.3 563.5 573 566.7 568.1 550.1 535.7 526.9 492.4 346.7 Dead
29 6 Vehicle Control 699 179.6 212.4 243.4 268.6 295.8 312.7 321.2 331.3 349.1 361.5 370.2 385.9 397.4 402.6 425.5 444.6 449.9 481.2 486.9 495.8 502.4 511.6 516.4 525.1 545.7 550.1 555.6 556.4 539.9 530 498.7 476.7 474.2 444.7 295.1 Dead
30 6 Vehicle Control 729 183.6 208.1 236.8 256.2 275.8 293 301 308.8 320.4 330.7 338.9 349.5 357.9 376.7 395 420.3 415.2 448.1 465.7 473.2 477.5 489.5 499.1 517.2 525.7 524.1 535.7 537.7 544.9 551.3 546.5 539 542.4 531.4 541.6 540 530.6 Terminal Sacrifice
31 7 Vehicle Control 455 159.7 194.3 218 251.4 261 278.7 292.5 304.8 317.2 330.7 335.1 348.2 350.7 377.5 399.7 406 431.7 453.6 460 472.4 474.4 485.4 498.5 507.3 524.3 515.5 Interval Sacrifice
32 7 Vehicle Control 671 179.6 209.2 240.8 262.7 277.7 296.8 307.6 320.8 328.9 338.7 345.2 359.7 357.5 385.5 405.8 427.4 446.2 460.1 468.3 473.1 478.3 491.1 498.2 508.1 519.4 509.7 509.7 498 486 480.2 454.2 406.3 389.5 292 Moribund
33 7 Vehicle Control 573 188.2 226.7 261.7 295.2 316.1 333.8 351.4 364 380.6 392.8 400.2 413.3 415.4 443.9 461 480.2 487.7 509.5 519.7 525.5 544.3 559.9 565.7 577.8 585.7 590.1 592.6 589.9 567.8 485.9 442.7 Moribund
34 7 Vehicle Control 455 195.8 221.9 248.8 267.3 282.5 302.1 313.4 318.9 336.1 349 350.1 365.3 358.9 389.7 402.3 417.3 438.1 462.8 479.3 490.2 505.8 523.5 531.4 548.6 562.9 559.2 Interval Sacrifice
35 7 Vehicle Control 729 172.7 194.1 222.4 240.7 252.6 265 272.4 286.4 296.1 309 315.1 321.9 320 346.5 358.6 371.3 393.6 402.9 409 418 431.7 433.7 446.6 461.9 469.4 473.2 479.8 477.2 474.1 480.6 481.4 474.4 474.3 454.4 450.4 447.1 443.5 Terminal Sacrifice
36 8 Vehicle Control 729 163.8 196.7 226 254.6 268.9 288.5 296.4 304.2 315.2 331.2 333.1 352.6 356 380 401 402.5 428.5 449 456.2 465.4 478.3 486.3 495.6 507.9 513.9 526.9 530.6 531.3 528.5 529.2 478.2 500.6 520.4 497.3 499.6 473.8 415.4 Terminal Sacrifice
37 8 Vehicle Control 729 201.2 238.6 267.2 293.5 301.6 317.5 326.2 329.2 338.3 353.7 350.1 361.7 363.8 390 406.8 413.8 440.6 464.2 471.4 483.2 500.1 510.1 519.5 536.2 542.2 555.3 564 566.2 568.4 562.7 557.8 553.8 563.3 531.5 434.8 457.8 463.8 Terminal Sacrifice
38 8 Vehicle Control 730 197.1 226.4 256.1 275.8 295.5 312.8 325 328.4 340.4 358.2 361.8 377.6 379.8 407.2 429.2 428.9 446.9 477.3 484.4 494.9 509.1 512.8 524.9 537.8 542.1 552.9 558.1 566.1 562.3 573 550.1 545.9 544.4 498.6 465.6 450.5 434.3 Terminal Sacrifice
39 8 Vehicle Control 720 202.9 235.9 270.5 298.9 320 339.4 352.5 361.9 374.2 383.7 388.4 400.2 404 426.5 449 457.8 477.1 502.2 504.7 516.6 504.4 523 548.1 561.5 570.8 577.4 588.6 582.6 572.6 572.7 553.2 540.5 540.9 507.1 451.4 366.6 Moribund
40 8 Vehicle Control 728 186.6 209.4 237.2 275.2 280.5 292.6 311.2 316.9 331.8 342.6 346.7 356.4 357.5 380.7 401.1 400 415.8 435.3 442.8 452.7 462.5 459.8 472.8 485.1 482.1 479.2 466.8 468.6 466.8 467.9 439.1 440.1 449.1 437 436.4 420.1 411.3 Dead
41 9 Vehicle Control 611 188.6 229.1 265.8 281.2 299 322.3 336.6 348.7 360.8 371 374.2 393.5 396.7 425.1 443.6 459.1 475.8 499.7 508.1 525 517.6 535.5 532.3 542.9 547 549 548.1 540.1 528.8 524.9 500 416 Moribund
42 9 Vehicle Control 729 177.8 213.1 245 273.2 294.9 311.6 324.6 336.9 349.8 358.4 364.5 380 381.3 412.8 425 437.6 454 471.6 482.7 494.9 501.9 510.4 512.3 509.7 510 511 517.7 513.9 515 513.1 499 501.2 490.8 482.1 480.1 477.6 480.1 Terminal Sacrifice
43 9 Vehicle Control 453 191.1 221.4 255 275.6 290 306 324.3 335.1 349.7 360 360.7 377.8 382.3 414.3 418.2 438 451.5 475 476.9 491.3 497.4 503.4 509.6 508.6 508.9 512.4 Interval Sacrifice
44 9 Vehicle Control 729 203.2 244.8 276.5 299.3 317.6 330.9 340.2 348.4 360.1 369.6 372.2 394.2 400.7 427.1 438.4 440.5 467.5 488.7 502.2 524 525.6 546.5 547.3 560.3 560.8 567.3 572.1 572.3 574 571.3 554.2 556.8 559.2 550.6 555.3 551.5 523 Terminal Sacrifice
45 9 Vehicle Control 455 189.1 223.2 255.8 286.9 300.9 318.1 328 335.8 341.8 345.9 349.5 372.1 375.4 411 420.8 428.8 448.5 461.8 480.7 496 499.4 519.1 529.2 538.3 552.5 554.9 Interval Sacrifice
46 10 Vehicle Control 453 176.6 201.6 223.1 237.9 248.5 267 274.2 283.2 293.5 301 302.8 317.7 316.5 337.8 353 371 387 401.5 405.3 416.9 421.6 439.6 451.5 453.8 463.8 473.4 Interval Sacrifice
47 10 Vehicle Control 408 194.6 227.3 258.4 279.1 294.5 316.2 335.1 351.5 366.9 377.7 386 401.3 404.5 425.6 429.5 469.9 493.7 517.3 520.5 535.6 539.5 549.5 559.8 591.4 604 Moribund
48 10 Vehicle Control 335 172.6 206.7 232.8 253.6 269.5 290.2 300.9 314.7 327.4 339 340.1 355.9 356.6 375.9 400.1 419.6 435 449.3 458.8 477.2 479.6 487.1 Gavage Death
49 10 Vehicle Control 730 173.5 204.3 231.4 260.4 275.1 296.9 301.2 306.7 327.1 348.8 349.3 363.7 364.6 385.5 402 414.7 432.7 446.8 453.2 466.8 464.4 481.2 489.2 489.8 506.3 506.7 497.4 504.2 467.6 455.5 440.7 426.3 418.5 415.5 418 398.5 401.5 Terminal Sacrifice
50 10 Vehicle Control 472 175.2 208.2 239.1 258.1 269.4 288.4 299.3 309.2 325.6 336.4 342.9 353.1 353.9 376.1 385.7 390.8 420.5 433.5 438.5 434.9 439.9 461.5 470.2 481.1 493.2 432 351.6 Moribund
51 11 Vehicle Control 455 197.4 222.8 258.9 294.7 289.2 308.8 320.6 324.2 337.9 353 358.3 365.5 372.2 393.7 406.6 438.7 456.3 472 487.1 504.7 512.1 534.6 540.4 553.7 565.5 569.1 Interval Sacrifice
52 11 Vehicle Control 729 194.1 224.6 248.8 265.7 285.6 301 314.5 317.8 330.8 343.4 345.7 355.1 367.4 380.9 386.8 413.6 434.8 454.1 462 481.2 488.6 502.8 512.5 527 540.8 536.1 543.2 553.7 544.2 542.5 533.8 524.6 528.9 509.4 494.5 500.8 473.5 Terminal Sacrifice
53 11 Vehicle Control 729 175.9 210.3 239.9 262.3 279.4 306.8 304.6 305.9 325.3 339.2 345.4 357.9 361 380.2 391.5 416.2 432.8 446.7 449.8 467.7 464 476 486.6 501.2 515.7 514.2 528.8 536.5 533.7 533.3 529.1 518.7 506.8 495.7 489 485.1 478.4 Terminal Sacrifice
54 11 Vehicle Control 372 177.7 212.9 245.5 267.2 285.6 302.4 315.4 319.6 338.9 350.7 358.7 370.8 378.9 404.5 420.9 431.5 455.4 466.6 482.3 487.8 485.3 499.9 359.9 353.8 Moribund
55 11 Vehicle Control 729 191.5 220.2 251.1 264.2 290.2 302.7 312.7 313.5 333 345.3 348.9 360.9 364.9 387.6 397.1 413.8 432.3 438.6 456.3 476.3 474.9 489.2 492.1 503.7 522.1 518 536.6 542.3 531.1 542.8 542.1 542.6 532.4 497.6 489.8 484.5 472.7 Terminal Sacrifice
56 12 Vehicle Control 578 194.2 219.8 241.5 261.1 272.4 287.8 296.5 304 313.3 324.8 333.4 347 355.8 358.5 374.9 395.7 404.8 432 436.1 445.1 455.3 471.6 475.8 485.3 497.2 498.7 503.9 520.8 499.8 490.9 346.1 Dead
57 12 Vehicle Control 601 184.6 208.1 240.9 264.1 280.5 299.4 308.4 313 325.7 340.8 339.7 353.5 362.6 374.7 394 401.2 424.2 446.2 448.5 461.2 472 482.2 493.5 500.2 511.9 509.4 517.9 522.5 516.3 534 516.3 471.6 Dead
58 12 Vehicle Control 730 189.6 222.1 254.7 277.3 294.9 314.5 330.9 341.4 351.1 360.1 366.2 375.1 383.6 391 411.3 430.1 446.9 474.2 473 479.4 484.1 494.4 494.2 502 508.9 500.7 509.8 508.5 505.2 506.1 503.1 497.9 496.1 490.8 476.5 488.7 484.6 Terminal Sacrifice
59 12 Vehicle Control 729 190.3 211.7 247.7 268.2 283.2 298.2 313.2 321 329.8 341.6 349.8 357.6 364.6 383.6 411.4 423.6 431.8 459.7 470.4 479.3 494.2 503.2 508.9 526.9 528.1 518 518.6 508.8 503.5 498.1 491.1 487.5 487.2 478.1 457 467.8 464.5 Terminal Sacrifice
60 12 Vehicle Control 622 182.3 210.2 240.3 254.9 278.1 298.3 312.8 325.4 337.8 348.7 353.8 366.3 374.5 393.4 409.1 429.7 439.3 471.9 476 487.1 493.4 503.8 500.3 513.1 521.1 509.1 505.1 515.5 508.5 521.3 545.6 575.9 Moribund
61 13 25MG/KG 482 176.3 210.7 246.2 239.3 271.2 293.7 304.4 318.7 330.3 343.8 353.7 364.5 373.3 405.7 424.2 437.2 450.9 467.7 470.2 467.2 472.7 471.3 475.9 472.5 446.6 452.4 407.5 Moribund
62 13 25MG/KG 673 184.7 208.7 246.9 241.5 273.4 293.9 305.8 313.1 326.1 340.2 343.1 363.7 362.3 377.1 394.7 405 408.8 425.8 441.1 450.9 447.2 468.7 474.9 479 489.3 491.9 497.7 497.7 498.1 507.7 505.1 503.1 496.6 417.7 Moribund
63 13 25MG/KG 730 167.4 202.5 243.2 239 269.7 299.2 307.8 319 333.3 344.4 354.3 367.6 366.9 396.4 420.6 426.9 437 466.8 481.5 485.4 507 517.6 530.3 534.6 552 547.4 561.7 563.6 561.8 564.6 551.4 528.5 501.9 432.2 436.1 421.2 410.5 Terminal Sacrifice
64 13 25MG/KG 453 170.7 200.2 222.3 212.7 249.7 269.6 281.6 290.7 305.2 313.1 320.6 334.2 330.7 362.3 378.2 378.1 393.7 410.9 425.1 432.3 439.2 452.8 457.4 459.4 471.1 465.7 Interval Sacrifice
65 13 25MG/KG 639 170.4 202.6 237 255.3 259.6 276.6 284.8 299.2 312.5 322.5 330.1 344 345.1 370.8 384.8 392.3 408.9 423.6 433.9 437.7 446.5 457.4 465.5 480.1 490.7 498.5 508.6 514.5 512 520.5 486 431.7 291.8 Moribund
66 14 25MG/KG 729 170.4 205.5 234.1 256.6 275 290.2 303.5 311.5 324.1 336.1 336.3 347 353.8 381.8 399.5 393.4 404.5 437.1 437.9 454.4 462.1 459.5 482.5 489.4 492.5 506.9 509.9 501.5 500.2 505.4 483.9 479 458.4 417.7 407.7 385.8 372 Terminal Sacrifice
67 14 25MG/KG 645 154.6 186.1 211 235.3 260.2 274.3 286.9 296.6 308.7 321.7 326.6 336.6 343.7 365.6 388.3 390 400.2 431.1 422.4 439.7 448 453.2 474.1 480.8 489.1 494.1 505.5 496.2 489.6 499.3 460.9 432.2 307 Moribund
68 14 25MG/KG 622 197.1 227.2 260.5 275.2 295 313 328.1 341 353.5 364.1 369.4 381.3 390.1 416 423.6 428.8 435.3 467.5 475.8 484 487.3 491.6 508.6 517.5 529.3 538.5 546.3 548 538 554.7 520.6 365.5 Moribund
69 14 25MG/KG 453 184.7 224.8 254.9 265.6 298.6 314.2 321.5 328.7 349.6 363 365.4 373.7 380.3 413.2 434 443.2 452.8 481.3 492.3 503.9 511 510.3 517 514.8 518.6 525.4 Interval Sacrifice
70 14 25MG/KG 577 196.6 227.4 262.1 294.5 294.1 312.8 324.2 333.7 347.3 363 368.3 382.9 386.3 409.1 438.6 444.4 457.2 486.3 497.5 507.6 517.4 525.2 521.8 535.1 554.6 575.5 585 582.6 580.5 581.4 465.6 Dead
71 15 25MG/KG 611 202.2 233.2 263.2 288.4 307.7 321.9 332.1 345 353.8 360.7 370.7 382.8 389.1 414 437.2 443.9 463.4 482.8 482 489.4 492.4 505.2 529.8 520.3 536.2 542.9 549.1 538.3 540.8 539.4 449.5 372.1 Moribund
72 15 25MG/KG 613 181.6 214.1 240.7 259.1 278.8 297.8 307.1 312.6 323.3 332.9 338.8 351.3 352.9 386.8 393 398.3 423.3 452.5 457.3 470.1 471.9 484.5 502.7 507.9 515.8 532 546.9 542.7 551.5 538.8 498.5 377.3 Dead
73 15 25MG/KG 625 175.4 208.8 238.2 256.7 281.5 298.7 311 320.6 333.9 339.2 348.5 363.7 359.2 394.3 403.6 412.8 439.2 466.4 471.3 482.7 489.1 495.1 516.4 520.4 526.4 539.3 546.6 543.8 543.1 541.2 509 414.1 400.8 Moribund
74 15 25MG/KG 729 179.3 213.2 249.2 278.4 287 304.7 313.7 311.2 325.7 325.1 334.7 351.2 359.6 393.1 399.6 401.9 430.6 455.8 457.9 461.6 468.5 479.9 487.6 494.3 501.6 517.2 507.6 522.4 521.4 530.1 519.8 517.3 500.3 476.7 470.1 461.3 450.3 Terminal Sacrifice
75 15 25MG/KG 593 218.3 250.4 286.1 304.5 322.7 337 354.2 366.4 381.4 391.7 398 416.8 424.3 460.6 480.1 509 538 558.6 574.7 585.8 586.8 610.8 630.1 640.2 647.3 657.7 643.2 551.9 537.5 504.2 317.2 Dead
76 16 25MG/KG 625 209.9 237 271.1 286 299.3 316.8 329.9 339.3 350.1 368 370.3 374.9 383.5 404.9 419.5 435 451.1 484.7 495.4 513.3 511.3 525.3 538.2 534.8 546.3 547.5 530.9 536.5 519.3 495.6 464.3 405.8 394.7 Moribund
77 16 25MG/KG 652 180.1 214.1 246.9 270.1 289.2 304.3 316.3 329.6 339.8 343.8 352.1 369.1 371.5 401.9 408.5 421.5 445.1 465.5 484.8 493.1 492.3 508.6 514.1 520.2 536.9 541.2 527.8 519.2 520.5 498.9 489.1 477.7 339.9 319.1 Moribund
78 16 25MG/KG 661 184 211.9 245.2 270.5 288.5 306.9 319.6 322.5 335.6 340.2 346.8 361.4 362.5 383.8 390.6 404.3 428.5 449.8 461.5 473.9 470.8 494.3 512.6 508.6 528.1 527.6 519 529.4 525.8 510 505.1 479.9 465.8 350.3 Dead
79 16 25MG/KG 675 178.9 208.2 237.4 253.6 266.6 286 293.6 301 317.1 324.5 334.1 344.5 351.1 378.8 391.3 406.6 431.9 451.9 457.8 470.3 473.8 482.1 494.9 494.6 507 512.4 508 517.9 526.7 499.6 521 515 522.2 356.5 Moribund
80 16 25MG/KG 456 203.5 275.3 310 330.6 351.9 369.2 373 377.5 388.2 404.7 408 422.6 425.3 458.4 470.2 477.4 504.7 519.7 528.7 534.2 530.2 554.4 570.8 567.8 583.1 584.3 579.2 Interval Sacrifice
81 17 25MG/KG 671 173.6 203.8 235.5 256.5 275.9 289.9 296.6 306.2 317 328.9 333.7 341.9 367.4 366.2 376.5 390.2 410.5 429.3 445.1 461.4 452.2 469 478.7 485.4 497.5 503.1 503.9 521.5 494.3 481.7 458.4 448.3 411.4 340.3 Moribund
82 17 25MG/KG 729 177.7 209.8 240.5 261 277.7 290.1 300 312.3 327.8 340.7 347.5 360.1 358.7 392.9 401.9 417.5 446 461.6 466 485 485.1 497.6 505.1 503.8 514.1 508.9 512.1 508.8 513.5 510 510.3 502.3 501.6 486 469.3 457.9 448 Terminal Sacrifice
83 17 25MG/KG 729 171.6 203 230.8 257.5 272.5 289.5 297.2 306 321.3 337.3 342.1 356.4 345.1 383.2 401.6 407.3 431 447.2 450.9 462.6 455.6 468 474.9 478.8 487 483.8 482.4 485.1 474.8 476.2 469.3 454.9 447.3 428.8 413.9 405.8 399.5 Terminal Sacrifice
84 17 25MG/KG 503 172 202.8 233.7 249 260.7 278.4 286.6 296.6 303.7 318.5 328.6 329.4 330.1 353.7 357.1 374.5 384.4 390 397.2 408.4 408.2 418 425.9 426.3 440.6 436.8 422.7 362.3 Moribund
85 17 25MG/KG 645 202.4 228.4 255.1 280 294.4 310.5 316.4 323.1 336.5 352.2 356.2 366.6 371.8 400.6 417.4 424.9 449.7 462.7 477.8 492.3 493.2 508.1 520.1 519.8 535.2 532.8 526.5 526.3 515.6 503.9 481.4 454.8 322.4 Moribund
86 18 25MG/KG 352 176.9 214.5 241.7 269.1 286.9 308.1 306.3 320.5 335.8 345.8 357.6 369.9 368.5 390.2 409.9 426.7 432.1 455 466.3 472.9 480.1 494.4 497.4 Gavage Death
87 18 25MG/KG 455 188.2 216.9 250.4 269.8 285 304.9 308.9 318.7 342.3 353.6 357.9 368.2 368.4 396.1 412.5 436.7 453.3 467.9 479 483.2 502.3 517.4 513.3 526.7 542.2 543.6 Interval Sacrifice
88 18 25MG/KG 694 168.1 210.7 244.6 271.5 287.6 306.4 309.8 320.2 337.9 351.2 360.7 379.8 358.1 397.3 419.5 443.6 452.1 476.4 486.5 492.8 502 527.6 522.9 544.4 564.2 555.5 560.9 557.1 533.2 529.5 513.4 485.1 475 440.6 320.1 Moribund
89 18 25MG/KG 343 185.6 218.8 243.8 271.6 290 302.8 300.3 312.2 330.2 341.6 348.1 360.3 362.1 385.6 399.2 418.2 439.3 468.2 486.7 490.3 509.1 424.8|421.3 Moribund
90 18 25MG/KG 455 165.4 200.7 236.8 260.7 285.3 299.5 304.7 316.9 335.2 350.5 359.4 375.8 372.3 399.4 411.7 419 431 462.7 481.7 485.5 493.1 513.8 516.4 528.7 543.9 533.9 Interval Sacrifice
91 19 25MG/KG 600 174.8 209.6 242.6 271.1 288.7 307.8 318.2 326.3 316.9 331.4 346 362.7 370.7 397.2 407.7 426.2 440.9 461.5 477.1 482.7 476.2 500.3 499.2 506.3 513.9 504.2 522.7 524 522.6 531.1 523.3 518.9 Dead
92 19 25MG/KG 455 172.4 216.4 249.2 262.5 292.7 316.1 326.9 332 356.2 367 371.4 388.4 392.5 424.5 434.9 449.8 456.1 475 484.4 493.5 494.5 518 524 538.9 548.9 539.7 Interval Sacrifice
93 19 25MG/KG 453 197.5 231.1 262.1 298.7 301.4 317.6 330 337.9 353.6 362.4 368.2 383.1 384.8 414.1 427.6 428.5 446.3 473.3 487.4 501 488.5 515.4 517.4 524.2 535.1 536.7 Interval Sacrifice
94 19 25MG/KG 636 208.3 234.3 262.4 283.7 298.3 317.3 317.6 322.8 332.1 339.6 351.6 362.9 364.1 392.8 409.1 418.8 432.9 455.6 469.9 472.3 470.7 496.7 506.9 520.8 533.5 526.1 528.6 526.6 496.6 496.6 465.9 445 326 Moribund
95 19 25MG/KG 719 180.5 210.4 241.2 261.1 274.8 293 302.7 308.6 320.9 331 336.5 349.7 353 381.1 396.4 403.7 414.4 429 428.8 439.7 436.1 460 465 480.3 496.3 501.2 510.7 508 501.9 507.7 492.6 466.4 478.4 456.8 436.2 318.6 Moribund
96 20 25MG/KG 680 170.4 204.2 236.4 260.4 276.1 294.2 304 306 325.7 336.3 337.3 351.4 353.9 386.9 408.2 416.1 441.3 465.2 471 480.6 483 486 496.7 502.3 505.5 507.8 505.9 507.5 497.2 482.1 464.8 457.8 428.3 322.2 314.1 Moribund
97 20 25MG/KG 675 173.5 204.8 228.2 252.9 276 290.8 302.9 310.3 318.4 330.2 335.8 345.2 347.5 378.9 397.2 392.8 419.5 438.8 446.8 457 462.8 468.4 484.3 497 510.7 523.8 531.4 535.3 532.6 530.2 500.5 482 447.7 321.6 Moribund
98 20 25MG/KG 657 193.1 227.4 264.4 285.4 306.7 325.4 339 345.8 361 374.8 371.6 390.2 397 431.7 456.6 458.9 482.9 505.8 515.1 531.2 529.7 544.2 552.5 559.6 566.9 572.6 572.9 567.1 548.3 528.2 495.4 414.4 299.7 276.6 Moribund
99 20 25MG/KG 666 185.4 228.4 254.7 283.6 299.5 319.7 328 332.6 349.3 366.2 360.6 375.9 380.8 408.3 429.7 426.5 451.1 471.4 486.7 503.2 512.3 522.1 541.7 546.2 554.1 561.9 569.7 570.4 565.6 559.8 544.6 568 514.7 504.7 Moribund
100 20 25MG/KG 492 172.8 204.5 228.4 244.3 265.7 282.5 292.6 300.7 318.9 326.9 324.7 333.7 329.9 357.7 368.8 374.1 392.3 413.3 419.1 423 422.3 432.1 439.3 451.5 457.9 461.3 459.5 465.6 Moribund
101 21 25MG/KG 615 178.5 204.7 242.3 260 277.9 296.1 310.7 320 320.2 328.9 339.9 358.7 361 403.2 417.1 423.3 448.3 486.4 495.4 513.1 516 525.7 535.8 547.2 543 541.8 538.9 504.8 503.8 336.5 460.8 328.8 Moribund
102 21 25MG/KG 453 157.5 186 216.9 233.3 247.4 261.7 274.5 281.4 284.6 295 296.7 314 317.2 352.5 367.4 380 400.3 426.6 438.5 453.2 456.7 465.9 482.4 484.5 490.2 492.4 Interval Sacrifice
103 21 25MG/KG 660 179.9 207.6 233.9 259.7 280.1 297.3 313.2 327.7 329.3 337.8 338.8 359.1 364.8 401.6 412.6 432.2 440.8 472.8 485.3 499.1 501.2 510.1 518.9 521 531.9 537.4 539.8 537.3 528.4 530.6 512.5 496.2 410.2 324 Moribund
104 21 25MG/KG 518 171.5 210.2 247.4 275.6 289.7 312.9 328.1 331.6 344.2 345.5 351.8 369.5 378.5 408.1 419.7 440.1 462.1 496.5 499.9 514.1 519.2 532.1 542.5 550.2 550.2 555.1 545.7 526 445.2 Moribund
105 21 25MG/KG 90 159 199 233.2 249.4 279.5 296.2 309.3 314.1 317.4 326.2 331.9 351.9 355.1 Gavage Death
106 22 25MG/KG 692 191.3 227.6 260.3 274.2 291.9 307.5 315.4 319.9 334.8 338.5 340.9 353.5 361.7 386.8 397.6 416.7 421.3 450 461 480.8 484.3 499.8 512.6 511.8 531.1 535.7 535.3 535.8 539.3 542 531.8 537.3 518.5 468.6 347.5 Moribund
107 22 25MG/KG 631 223 264.3 302.9 328.6 350.7 368.7 371.6 386.4 400.9 412.9 418.2 432.7 444.1 477.9 487.3 509.3 506 537.5 547.6 563.1 560.4 574.3 599.2 602.9 611.6 607.3 602 589.9 562.2 470.7 429.8 386.2 315 Moribund
108 22 25MG/KG 569 185.4 215.8 245.5 260.9 285.1 297.3 303.9 311.1 324.1 326.6 326.3 338.8 341.9 368.3 373.6 366.7 379.9 417 431.2 451.6 448.9 470.2 483 485.3 509.4 516 514.1 497.3 481.1 384.1 361.6 Dead
109 22 25MG/KG 730 167.3 210.1 241.6 262.6 278.7 296.5 304.5 309.2 318.4 325 333.6 345.5 344.4 370 386.1 397.8 373.8 437.6 452.6 473.7 474.1 486.4 502.5 504.7 510.5 517.9 518.3 519.9 523.9 524.3 507.5 510.7 480.8 360.7 357.1 338.3 342.4 Terminal Sacrifice
110 22 25MG/KG 729 199.2 233.4 260.6 280.7 296.2 313.3 311.6 315 327.5 333.5 336.2 353.5 355.1 382.2 389.2 389.6 395.2 417.4 428.3 446.8 447.3 456 465.9 474.8 486.3 492.9 487.2 481.3 479.7 470 449.1 437.8 420.6 417.9 404.4 402.1 395.8 Terminal Sacrifice
111 23 25MG/KG 600 175.3 217.2 247.2 261.3 283.5 302.5 316.1 315.5 331.8 340.8 344.5 359.5 363.3 386.5 379.3 402.2 428.4 438.8 454.4 479.6 478.4 495.1 506.8 509.3 527.3 522.7 518.7 519.5 512.9 503.7 456.8 439.1 Dead
112 23 25MG/KG 729 176.7 217.8 247.3 254.7 287.5 310.4 326.8 332.9 353 356.1 360.4 377.8 381.1 403.8 409.9 417.6 435.8 451.9 462.6 484.4 473.3 497.7 506.6 514 532.8 538.6 548 518.9 555.1 558.2 553.4 539.4 502.6 464.5 445.5 370.4 309.5 Terminal Sacrifice
113 23 25MG/KG 698 180.3 206.8 237.2 264.9 272.1 290.3 301.6 311.3 329.3 334.5 340 351.5 354.3 386.8 395 402.6 421.8 431.6 449.3 465.2 466.6 488 498.4 503.1 518.9 522.8 523.3 517.4 504.5 508.9 495.2 492.5 477.1 443.1 337.5 Moribund
114 23 25MG/KG 729 189.3 220.8 255.8 271.4 288.5 308.7 329.6 338.7 352.7 363.1 372.2 381 386.6 413.5 420.7 425.3 450.4 469.4 479.1 489.9 486.8 503.1 509.3 513.7 526.1 524.8 519 517.1 509.5 509.9 491 479.2 466.4 446.3 435.8 428.2 426 Terminal Sacrifice
115 23 25MG/KG 456 181 211.2 239.3 259.2 273.5 289.8 302.1 309.5 317.7 323.2 329.3 341.6 345.5 364.8 379 394.3 417.9 438.8 451.3 463.9 465.3 480.6 482.2 484.9 488.5 484 485.2 Interval Sacrifice
116 24 25MG/KG 671 162.1 194.7 223.9 248.7 264.3 277.6 291.6 307.5 318.6 325.6 331.6 343.5 350.6 370.9 382.2 398.5 409 428.3 445.4 444.9 448.2 462.6 442 469.2 479.9 487.1 499.5 490.5 477.6 466.7 427.3 384.6 354.8 336 Moribund
117 24 25MG/KG 663 175.1 208.3 237.4 260.4 276.1 285.6 295.1 308.5 324.1 335.2 338.2 350.9 352.2 375 393.4 393.4 408.4 433.5 447.7 456 451.4 477.7 484.1 495.9 506 506.9 512.5 510.7 481.8 484.7 461.1 368.2 385.5 354.9 Moribund
118 24 25MG/KG 583 176.5 225.5 259.3 290.9 303.4 315.2 322.5 328.3 346.4 364.3 366.6 383.2 383.5 403.6 417 428.7 432.4 449.6 469 478 460.7 492.6 486.4 496.3 501.1 507 482.8 453.3 418 382.5 276.4 Moribund
119 24 25MG/KG 377 163.4 209.3 243.5 283 304.6 321.4 332.3 345.2 362.5 376 381.6 395.9 403.6 432.2 451.5 467.8 479.7 508.4 519.6 522.3 524.8 554.1 560.5 560.1 Gavage Death
120 24 25MG/KG 455 162.4 203.4 235 258.1 275.4 285.4 295.8 302.7 321.5 333.2 339.5 354 359.8 388.8 401.4 412.6 421.5 452.6 461.9 473 468.3 489.4 490.3 498.6 504.3 501.4 Interval Sacrifice
121 25 50MG/KG 580 166.6 206.5 237 253.5 270.2 290.8 302.8 318.5 334 343.8 352.9 361.2 345 381.1 411.6 415.8 443.8 452.2 462.2 468 468.9 486.8 482.4 488 491.4 491.9 500.7 492.4 476.8 463.7 400.1 Dead
122 25 50MG/KG 625 161.5 202.9 241.1 252.5 276.3 292 303.9 316.5 324 334.6 344.2 355.4 357.5 384.9 396.5 406 425 438.4 456.4 467.4 464.9 491.9 489.3 491.1 503.9 497.8 510.7 503.8 484.8 477.2 456 312.3 297.1 Moribund
123 25 50MG/KG 473 175.9 202.7 222.8 233.4 246.5 260.9 270.5 277.1 284.1 291.6 295.6 301.3 299.7 327.8 336.7 334.4 356.5 374.7 392.5 400.1 404.1 408.9 411.9 421.1 427.9 424.5 316.5 Moribund Sacrifice
124 25 50MG/KG 596 184.7 209.2 231.2 242.5 260.3 276.7 291.4 306.4 314.9 325.6 330.7 340.9 335.1 367.6 385.7 391.9 406 426.2 435.6 442.8 446.8 470 473.2 472.5 493.1 504.6 514.1 506.8 510.1 506 400.5 374.7 Moribund
125 25 50MG/KG 539 173.3 201.1 228.5 248.8 268.2 284.5 308.1 313.7 325.6 336.1 343.7 352.3 347 378 397.4 395.9 426.5 436.8 460 458.4 462.3 488.1 490.3 493.5 505.8 512.5 522.8 515.3 370.7|369.3 Moribund
126 26 50MG/KG 546 215.1 247.6 275.4 297.3 312.8 335.2 348.6 363 362 371.7 372 383.9 388.1 412.1 429.5 411.9 425.2 440 450.7 452.9 467.1 463.3 469 479.4 480.3 475.9 487.9 494.4 467.7 339.4 Dead
127 26 50MG/KG 631 170.7 215.2 244.8 269 282.6 302.8 313.2 329.1 336.1 343.6 348.8 362 361.2 374.6 397.5 396.7 412.5 414.2 425.1 435.8 439.1 448.8 458.9 464.1 475 480.8 496.6 495.4 484.3 496.2 467.4 370.8 286.2 Moribund
128 26 50MG/KG 622 160.3 189.8 230.8 254.1 264.2 282.4 295.7 308.8 318.1 323.6 335.3 345.9 347.5 377.7 393.9 410.4 434.3 448.9 461.2 477 477.1 491.7 497.7 503 509.2 511.4 522 509.4 508.5 506.2 472.2 340.7 Dead
129 26 50MG/KG 428 153.6 182.7 218.1 245.2 261 280.9 300.8 315.5 321.5 330.1 334.4 345.7 348.8 375.5 401.5 393.8 404.2 420.4 436.5 447.8 453 457.6 468.7 474.8 479.8 480.6 Gavage Death
130 26 50MG/KG 594 168.7 186.9 216.2 232.6 245.7 259.9 270.4 278.7 285.6 293.3 292.1 300.5 304.2 317 336.2 327.5 348.6 359.5 378.8 386.2 395.8 401.1 409.4 418.7 425.7 431.5 444.2 440.1 444.7 455 311.7 Dead
131 27 50MG/KG 622 195.7 227.2 265.6 288.8 302.8 313 329.5 341.4 350.3 359.2 367.8 380.2 383.6 399.9 416.9 426.1 444.9 447 458 470.2 478 480.4 497.4 496 501.7 502.2 505.1 489.9 488 484.1 456.9 322 Moribund
132 27 50MG/KG 628 177.2 202.7 234.6 251.3 266.1 285.5 298.9 316.7 322.8 336.7 344.9 353 356.7 378.8 401.2 399.8 417.1 435.1 446.2 465.9 469.5 488.5 504.7 507.4 514.6 516.2 526 525.6 520.5 519.4 504.8 444.1 373.7 Moribund
133 27 50MG/KG 63 163.7 202 240.4 260 283 302.4 315.6 326 341.7|343.4 Gavage Death
134 27 50MG/KG 602 166.5 196.5 219.7 242.3 256.3 270 281 292.2 297.4 300.9 308.4 315.5 315 332.2 358.7 370.1 383.7 400.7 409.5 416.4 425.4 435.1 450.8 446.7 445.5 436.3 435.9 429.7 424.3 402.9 311.5 268 Moribund
135 27 50MG/KG 588 150.3 183.4 219.4 239 260.3 275 289.7 304.4 315.1 331.7 341.8 349.1 349.5 371.6 396.1 391 418.9 430.4 433.9 435 443.2 457.1 466.7 474 490.1 492 502.3 500.8 496.3 473 339.5 Moribund
136 28 50MG/KG 455 162.8 196 225.8 244.5 266 283.4 299.7 313.2 325.9 335.2 342 352.7 355 376.1 386.3 403 424.6 424 442.1 457.8 452.4 470.5 474.3 472 492 477.1 Interval Sacrifice
137 28 50MG/KG 666 165.5 203.5 234.5 251.3 269.1 288.1 305.3 319 330.2 339.2 348.5 356.4 352.6 376.1 386.2 397.7 412.8 406.6 428.4 440.9 438.3 452.6 453.4 449 471.6 463.1 467.1 472.4 470.6 463.6 444.7 435 393.2 295.5 Moribund
138 28 50MG/KG 678 176.7 214.5 247.5 264.1 288.8 310.7 327.1 340.1 348.7 355.5 364.8 375.2 380.2 393.6 408.1 426.4 439.3 438.4 459.5 471.3 468.7 489.3 488.7 488.2 509.5 510.7 509.4 510.4 507.3 502.1 469.5 454.9 440.6 329.2 Moribund
139 28 50MG/KG 575 173.3 202.2 241.6 255.4 277.2 291.5 312.1 328.2 341.6 345.3 358.1 367.2 370.4 395.1 407.1 423.5 447.4 435.5 446.6 460.5 458.8 476 480.4 479.9 503.2 512.3 515.9 526.7 525.9 491.2 389.6 Moribund
140 28 50MG/KG 429 186.7 213.6 250.5 268.6 283 300 314.7 327.2 334.1 347.1 356.6 361.6 362.8 393.1 409.7 435.6 457 457.8 478.8 490.8 491.1 509.5 511.6 488.8 348.3 339.5 Dead
141 29 50MG/KG 531 174.4 211.6 240.6 269.9 276.2 291.2 302.8 316.7 329.3 336.2 346.4 353.8 357.6 379.7 396.8 404.4 426.7 425.9 443.8 462.1 467.4 476.3 482.3 491 505.7 507.5 518.2 523.2 337.7 Dead
142 29 50MG/KG 596 169.9 206.7 238.3 269.4 278.7 295.2 310.5 325.8 332.8 346.8 351.6 360.6 365.5 385.3 406.3 421.7 438.8 445.4 460.8 473.7 476.7 485.3 501.3 508.3 521.5 511.5 516.5 513.1 474.3 339.9 296.3 278.7 Moribund
143 29 50MG/KG 569 135.6 167 203.8 221.5 236.5 251.2 267.5 286.7 296.9 310.7 313 322.7 332.5 347.4 377.8 400.9 412.6 424.9 436.9 452.7 447 462.2 459.7 461.7 451.2 449.9 457.1 470.9 476.3 371.7 348.4 Moribund
144 29 50MG/KG 455 162.1 190.8 220.7 243.4 255.6 268.9 286.4 299.3 311.7 324.5 331.3 339.5 343.2 367.6 386.7 395.9 417.2 419.7 431.6 443.2 439.8 452.6 450.3 464 462.3 458.6 Interval Sacrifice
145 29 50MG/KG 496 186.9 220.8 247.9 265.9 289.3 306.2 320.4 336.3 350 363 367.3 379.4 385.7 403.9 421.5 445.5 461 469 479.7 493.4 502.4 507.8 512.2 514.4 515.8 501.4 482.1 341.2 Moribund
146 30 50MG/KG 453 195.9 230.3 266.3 281.5 297.2 310.4 327.9 339 351 359.4 366.5 377.3 376.5 392 418.6 421.8 415.5 446.4 469.3 476.8 481.5 494.5 491.1 498.9 503.1 501.2 Interval Sacrifice
147 30 50MG/KG 556 166.3 203.8 225.5 250.6 261.3 275.8 293.6 308 320.6 326 331.4 339.4 339.4 356.2 378.7 386.9 384.3 410 425.2 431.8 436.1 452.5 455.6 466.4 483 477.5 496.3 492.1 475.2 397.6 Dead
148 30 50MG/KG 643 146.9 167.2 199.1 217.7 231.9 249.1 262.5 277.3 288.7 293 298.3 309.6 311.2 326.7 358.8 359.1 368.3 383.1 402.2 411.5 416.2 427.8 427.1 430.8 447.2 446.4 461.6 466.2 459.1 465.6 446.8 425.7 289.3 Dead
149 30 50MG/KG 555 181.5 209.7 243.6 268.6 282.4 297.3 314.2 323.9 336.6 343.2 352.3 359.5 359.1 366.6 400 395.6 405.9 435.9 447.3 456.5 473 477.5 477.6 487.5 495.5 492.1 506.5 493.6 488.5 395.3 Moribund
150 30 50MG/KG 455 165.7 200.2 233.4 256.1 278 289.9 306.9 320.1 334.1 345.8 349.7 361.9 360.8 369.4 400.9 405.2 414 441.4 452.8 463.3 466.3 479.6 476.8 491 506.3 515.2 Interval Sacrifice
151 31 50MG/KG 622 155.3 190.9 217.9 238.9 249.2 266 282.2 292.9 304.4 312.3 321.9 332.7 332.2 348.8 371.6 379.4 392.2 398.7 418 418.5 427.7 441.5 438.1 455.5 465.5 460.7 465.4 466.1 459.4 439.4 404.3 373 Moribund
152 31 50MG/KG 453 189.2 217.9 234.7 256.1 257.7 272.6 291 305.2 317.3 325 330.9 338.2 334.2 353.2 366.6 374.1 388.4 395.2 404.8 410 414.5 427.4 425.9 434 442.7 442.3 Interval Sacrifice
153 31 50MG/KG 408 159.2 191.2 221.4 238.9 248.2 263.2 276.3 289.8 300.9 309.7 320 326.2 325 339.7 354.3 362.2 378.2 390.8 406.2 410.4 417.1 430.9 429.8 418.7 411.1 Moribund
154 31 50MG/KG 517 174.6 208.8 241.6 257.2 275.5 291.8 304.4 317.6 333.9 341.5 349.5 361.2 363.5 387.7 398.9 406.8 425.8 423.1 454.5 451 466.4 487.5 492.9 505.7 524.5 517 510.8 452.3 393.3 Dead
155 31 50MG/KG 601 183.6 208.6 239.1 259.4 266.2 286.1 304.5 317.8 328.8 339.5 351.6 359.6 361.1 379.4 402.4 411.1 423.9 434.6 451.4 449.2 460.4 479 472.5 482.5 502.2 497.5 500.8 488.9 483.4 459.6 310.8 260.7 Dead
156 32 50MG/KG 645 178.5 206.7 240.8 268.1 284 300 307.2 324.5 333.8 342.5 344.3 353.6 356.7 379.8 395.9 401.6 414.9 427.8 440.4 445.2 450.5 465 462.5 477.2 474.7 481.6 479.7 491.3 491 487.4 458.6 440.3 302.6 Moribund
157 32 50MG/KG 455 150.3 184 221.3 240.2 250.1 270.6 282.7 296.1 305.3 313.1 316.1 315 324.2 349.6 367.4 369.8 382.5 389 409.6 416.5 429.8 436.3 442.5 444.6 436.7 451 Interval Sacrifice
158 32 50MG/KG 694 161.7 195.8 226.5 245.4 265.6 281.4 288.4 304.6 311.2 313.2 316.6 329.3 328.3 352.8 363.4 369.4 386.5 404 416.1 420.8 425.4 433.4 442.9 447.1 445 451.4 445.9 454.1 449.2 441.9 405.7 392 372 352 355.5 Moribund
159 32 50MG/KG 545 174 201.3 231.8 244.7 263.3 275.3 287.8 297.8 312.8 322.7 325.2 325.9 333.2 358.2 375.3 375.7 402.9 419.3 431.7 443.7 451.1 459.6 473.1 480.7 492.2 497.7 495.8 497.2 364 318.5 Moribund
160 32 50MG/KG 506 184.6 217.7 250.4 276.9 288 303.3 315.7 326.5 341.1 348.6 353.1 363.1 363.6 388.7 402 420.2 436.2 452.9 466.6 475.4 479.4 493 499.6 510.4 509.5 520.6 512.7 415.5 Moribund
161 33 50MG/KG 456 170.3 195.9 222.8 243.9 254.9 275.7 288.6 298.6 311.3 320.7 329 333.2 333 346.5 373.5 386.4 398.2 413.9 419.5 429.5 445 451.4 464.1 471.5 483.2 493.9 493.8 Interval Sacrifice
162 33 50MG/KG 643 172 210.2 243.2 269.6 286.1 299 314.6 328.8 337.4 342.8 348.7 358.1 365.6 377.5 399.2 402.9 417.9 426.8 434.6 431 432.4 441.3 453.4 453.3 461.4 460.1 460.8 453 438.3 428 408.4 393.3 234 Moribund
163 33 50MG/KG 525 224.6 253.6 291.4 303.1 322.7 344 360.5 374.5 386.4 394.7 404.6 419.8 423.8 440.1 464.7 473.1 493.5 500.1 512.6 521.9 513.8 534.9 545.3 549.4 562.2 552.9 543.1 509.8 382 Moribund
164 33 50MG/KG 453 179.1 211.7 240.4 257.1 272.8 288.6 303.9 317.8 324.7 336.4 338 349.1 350.4 363.5 383 401.4 411.8 421.8 442.9 450.6 452.2 461.7 470.3 469.1 477.8 486.6 Interval Sacrifice
165 33 50MG/KG 615 166.7 205.3 239.9 265.1 277.9 301.5 318.5 336.5 344.3 347.1 352.9 365.4 372.2 398.3 414.9 428.8 443.4 451.6 467.9 475.5 477.3 488.8 489.2 494 494 496 498.1 500.5 497.9 471.4 442.2 319.2 Moribund
166 34 50MG/KG 548 191.1 223.4 254.5 276.6 289.4 310 322.9 334.4 343.1 353 362.3 373.1 378.7 399.2 416.6 437.7 439.3 444.1 471.4 478.8 487.1 502 495.3 502.7 514.9 516.3 512.7 503.7 483.9 370.4 Moribund
167 34 50MG/KG 506 199.8 232.4 257.6 282.1 296.8 314.5 331.1 340.9 354.7 363 370 382.9 387.9 401.2 410.1 425.1 437.7 439.8 481.7 494.9 506.8 526.8 528.9 520 538.9 529.8 511.5 377.3 Moribund
168 34 50MG/KG 453 185.2 221 250.8 281.4 293.7 309.6 322.1 331.1 340 350 362.7 369.2 374.7 389.4 412.9 430.5 438.7 435.2 463.3 478.6 486 499 506 504.8 525.3 528.5 Interval Sacrifice
169 34 50MG/KG 533 168.6 204.3 235.5 263.1 273.1 292.5 305.1 314.3 328.9 338.3 348.1 356.5 359.2 382.2 396.4 421.4 428.3 433 449.9 460.1 463.9 479.3 490.1 490.7 511.6 512.5 509.4 507 332.1 Moribund
170 34 50MG/KG 615 159.7 190.7 213.3 239.1 255.5 271.9 280.8 292.1 305 310.7 320.7 327.3 330.5 345.2 361.1 379.9 383.1 387.1 407.7 418 419.5 434.2 432.3 438.6 450.5 451 446.4 448.2 440.4 414.9 387.8 274.5 Moribund
171 35 50MG/KG 679 160.2 194.5 232.2 257.5 271.1 291.6 301.6 318.8 322.1 336 341.4 355.2 356.3 378.2 379.8 398.4 422.3 423.6 437.6 451.6 453.7 465.7 466.9 474.6 494.3 493 480.4 490.6 479.8 474.5 459.9 439.5 431.4 278.3 Moribund
172 35 50MG/KG 657 164.7 201.3 234.2 256.5 273 289.9 303.5 316 323.4 336.2 339.3 345.7 351.2 368.3 385.4 404.5 416.9 421.2 435.9 455.1 459.1 470.7 465.8 467.6 487.7 491.2 488.3 490.8 489.7 486.1 469.7 454.8 375.5 304.1 Moribund
173 35 50MG/KG 531 180.8 211.9 238.1 259.8 274 295.6 309.7 322.2 330.8 343 350.2 355.4 356.5 379 395.4 413.4 435.3 428.9 455.4 458.4 458.9 476.3 478.8 491.2 510.1 508 515.2 525.1 372.5 Dead
174 35 50MG/KG 630 179.1 212.8 231.6 251.5 266 279.7 287.5 300.9 313.5 325.2 333.3 344.1 345.4 362.7 374.6 387.9 401.8 412.1 427.4 440.4 441.1 457.4 456.9 464.1 478.9 480.5 476.7 479.8 478.8 479.6 456.9 356.9 281 Moribund
175 35 50MG/KG 498 182.1 219.7 253.7 276.4 288.5 295.1 306.2 318.8 327.8 332.4 339.3 348 351.9 370.6 384 400 411.2 412.8 424.5 433.8 432.5 445.4 450.9 451.3 462.2 446.5 419.8 304.1 Dead
176 36 50MG/KG 512 192.7 228.9 265.2 287.2 302.1 319.8 336.5 348.3 360.3 365.3 367.7 379 384.3 404.6 418.7 442.5 432.4 471.8 498.8 500 509.3 528.6 514.5 518.2 540.3 536.1 518.6 380.9 362.3 Moribund
177 36 50MG/KG 729 171.5 207.6 238.9 266 278.6 293.3 302.6 311.9 317.2 329.8 333 340.3 345.6 362.8 383.3 391.1 404.7 421.4 427.9 434.2 441.2 450.4 445.2 446.2 458.6 457.5 460 467.4 463.4 466.3 454.9 442.1 429.2 418.1 426.4 345.7 335 Terminal Sacrifice
178 36 50MG/KG 580 156.3 196.6 228.4 272.5 274 286.8 304.1 315.1 325.7 337.8 352 357.8 361.4 380.6 396.6 410.7 414.1 445.6 459.9 459 469.7 488.1 483.7 495.6 514.9 519.1 512.9 530.7 532.6 520.8 353.9 Dead
179 36 50MG/KG 730 163.5 217.9 243.7 253 269.3 286.3 294 305.5 316.6 321.1 327.1 331.1 334.4 353.8 369.2 375.1 372.7 391.3 402.2 395.9 411.5 417.1 416.4 422.9 433.5 428.6 437.2 441.2 438.4 443.3 442.1 435.6 431.2 423 413.8 410.8 404 Terminal Sacrifice
180 36 50MG/KG 607 186.6 193.5 218.9 240.6 260.9 276.9 287.6 298.5 306.3 312.5 322.2 331.4 335.8 353.2 376.9 386.7 391.6 407.6 422.1 417 425.5 430.4 427.7 442.4 461.3 456.6 462.8 473.6 473.8 475.1 436.7 310.8 Moribund
181 37 100MG/KG 589 164.6 194.3 224.3 254.8 262.1 280.3 294 305 317.8 334.7 346.1 354.3 350.3 366.8 396.9 408.9 410.8 429 447.5 449 456 474 472 479.8 486.1 479.7 476.6 477.9 460.6 454 302 Moribund
182 37 100MG/KG 19 155.8 183.2 202.3 Gavage Death
183 37 100MG/KG 510 181.2 210.5 229.5 253.7 253 269.9 289.4 305.8 318 318.9 330.2 337.3 332.5 343.2 357.6 367.1 376.3 388.8 406.4 412.8 424.9 439.1 443 452.2 460.6 459.5 474.7 378.7 Moribund
184 37 100MG/KG 563 147.2 171.6 197.5 213.3 233.6 246.1 255.8 266.4 278.3 286.9 295.8 308.5 307.3 324.7 336 355.6 352.3 368.9 380.5 375.1 387.1 397.6 385.1 394.1 393.1 381.2 391.2 382.6 331.1 243.8 Dead
185 37 100MG/KG 698 169.6 191.6 215 243.7 247.5 262.5 274.9 284.2 287.4 295.7 308.8 321.2 315.9 342.8 360.6 369 373.5 381.4 397.7 398.9 406.1 421.1 418.1 422.2 421.2 417.7 419.9 430 427.8 439.1 419.7 414.9 407.6 396 273.7 Moribund
186 38 100MG/KG 636 154 184.8 205.6 210.5 221.6 242.5 253.3 263.1 269.7 268.8 268.8 276.4 276.7 294.7 309.8 315 320.9 326.4 342.4 349.6 354.3 362.8 366.8 372.1 378.2 379.8 394.8 387.6 388 386.6 383.1 376.4 282.6 Moribund
187 38 100MG/KG 453 160.7 191.6 225.8 241.3 255.4 271.4 288.7 297.2 305.1 309.1 316.3 320.8 314.7 336.6 354.1 353.3 369.3 383 395.9 404.5 410.8 422 428.8 437.6 427.4 439.3 Interval Sacrifice
188 38 100MG/KG 426 166.4 206.4 247.2 269.7 283.5 301.2 314.4 325.4 343.6 350.2 359.6 366.8 369.3 402.5 418.6 426.9 446.2 468.3 484.6 486.4 490.1 502.8 468 482.3 470.8 Gavage Death
189 38 100MG/KG 630 170.2 202.6 242.8 265 282 303.1 320.7 323 338.4 340.5 351.6 361.8 348.1 365.1 392.8 398.2 404.4 424.7 436.2 440.4 447.9 452.9 456.2 469.5 450.8 478.9 493.5 486.9 485.7 469.9 452.7 367.2 289.6 Dead
190 38 100MG/KG 618 136.9 169.6 202 220.1 232.6 248.7 258.7 272.8 288.5 297.6 309.5 315.3 318.9 334.8 353.7 356.4 368.3 374.3 387.8 391.2 396.1 414.4 410.7 416.5 417.3 421.9 422.9 413.3 408 405.1 377.4 285.5 Moribund
191 39 100MG/KG 453 143.1 163.2 178.6 179.4 198.8 208.4 224.4 234.7 239.2 250.6 257.2 264.2 267.1 281.5 297.6 306.3 309.6 320.1 329.5 336.8 340.1 344.5 354.3 364.5 377.1 388.1 Interval Sacrifice
192 39 100MG/KG 496 177.2 196.5 217.8 240.3 246.8 264.8 274.7 283.2 294 307.9 314.9 321.7 319.9 341.6 366.8 376.4 381.2 397.9 411 420.3 420.8 436.6 439.7 441.3 450.6 453.9 445 356.5 Dead
193 39 100MG/KG 595 155.1 187.3 222.1 232.3 240.3 257.4 270.2 278.9 288.9 294.3 300.9 309.6 311.7 314.7 331.6 344.3 347.5 350.8 359.2 370.6 380.2 388 387.9 401.4 407.3 404.6 422 427.1 426.5 414.3 314.4 Moribund
194 39 100MG/KG 601 179.6 200.6 219.1 237.4 251.2 268 281.6 284.5 294.5 299 306.3 313.1 318.3 333.8 351.5 354.2 354.9 360.6 369.2 377.7 379.6 385.8 387.6 399.1 401.3 413.1 409.9 419.1 420.9 431.1 344.4 291.5 Moribund
195 39 100MG/KG 631 158.1 166.6 204.1 228.2 237.9 258.3 271.8 278 289.7 289.5 301.5 310.5 316.7 345.1 367.9 375.2 371.6 374.7 381.7 400.1 408.3 418.6 425.9 432.8 440.1 459.1 471 476 474.8 479.1 464.7 406.6 328.6 Moribund
196 40 100MG/KG 455 168.1 197.5 224.6 245.5 256.8 273.8 283.1 288.1 307.4 313.6 326 334.3 326 367.4 376.2 395.1 411.1 417.5 444.8 452.8 461.5 478.6 474.6 479.9 479.8 489.5 Interval Sacrifice
197 40 100MG/KG 420 172.4 199.2 222.9 244.5 249.4 263.7 271.5 272.4 282.2 289.7 300 305.8 302.8 325.9 332.7 337.7 344.8 355.6 365.8 374.2 379 392.3 382.8 384.8 361.8 Moribund
198 40 100MG/KG 580 179.7 215.4 243.3 266.8 271.5 293.9 303.9 313.3 325.1 335.7 349.2 357.6 358.5 384.4 399 406 412.2 424.6 444.7 444.6 441.6 460.8 455.4 450.9 469.1 458.7 462.7 459.6 457.4 382.5 370.3 Moribund
199 40 100MG/KG 456 164.3 188.4 212 232.8 232.3 250 262.9 263.1 278.9 285.3 297.1 301.8 302.7 320.8 335.1 342.5 355.1 362.3 381.3 391.7 388.1 401.2 409.1 414.5 416.1 418.2 417.8 Interval Sacrifice
200 40 100MG/KG 560 177.3 199.5 233.2 255.4 263.5 282.7 297.9 302.1 316.8 324.5 335.6 343 338.5 360.1 369.7 377.5 386.3 388.3 411.7 415.7 424.4 446.7 441.6 449.3 459.6 462.2 460.3 453.1 448.5 340.6 Moribund
201 41 100MG/KG 456 165.4 200.2 242.3 247.5 272.4 285.9 301.4 310.6 328.9 346 353.9 362.2 361 384.2 394.9 409.2 400.8 425.3 444.4 462 463.7 485 478.4 486.1 498.8 439.8 467.7 Dead
202 41 100MG/KG 503 178.4 211.1 237.6 276.7 274.9 288.9 306.1 310.8 321.6 331.4 340.1 346.8 350.3 373 385.1 404.3 401 422 444.7 454 458.4 468.4 463.4 468.6 479.9 474.4 482.7 380.5 Dead
203 41 100MG/KG 485 198.7 222.1 246 259.6 263.6 277.7 295.7 298.3 308.4 316.6 327.2 337.2 334.9 349.8 368.6 383.4 372.5 398.3 416.8 426 429.7 443 442.2 444.2 448.1 434.2 366.3|326.6 Moribund
204 41 100MG/KG 525 169.2 197.2 224.6 244.4 250.3 270.5 283.4 290.1 302.1 309.9 324.8 330 332.2 347.9 363.8 379.7 379.2 397.1 414.2 420.4 426 443.3 442 447.5 459.8 453.6 402.7 372.4 341.7 Moribund
205 41 100MG/KG 615 146.7 183.9 214.3 234.3 250.6 270.8 286.7 295.5 306.6 322 332.7 341.5 338.4 360 375.1 382.1 376.8 386.7 404.6 407 410.7 424.5 416.3 423.2 436.8 422.6 430.8 452.5 432.9 429.1 412.2 290.3 Dead
206 42 100MG/KG 496 195.3 221 253.8 268.6 288.4 297.6 311.3 311.8 323 334.4 344.1 354.5 349.3 371.8 389.3 404.8 412.4 416 436 429.6 438.5 455.7 449.1 460.6 463 461.2 463 365.8 Moribund
207 42 100MG/KG 380 175.7 209.2 237.7 258 268.1 283.7 296.9 301.8 308.8 323.6 329 336.9 333.5 343.1 368.6 374.1 366.1 381.9 403 398 399.4 404 390.1 370.4 Moribund
208 42 100MG/KG 518 143.5 184.5 217.7 246.6 253.5 268.5 276.5 286.2 299.2 316.4 326.5 336.3 333.9 337.8 371.3 376.6 364 389.9 404.2 405.2 407.7 425.1 420.2 442.6 457.2 448.3 452.8 403.8 347.7 Dead
209 42 100MG/KG 534 155.9 186.3 211.2 223.8 246.3 259.5 274.2 278.2 283.8 297.8 304.3 314.4 313.1 333.3 355.4 368.8 372 380.8 394.8 393.8 405.4 417.1 410.4 419.3 428.1 421.5 420.9 418.7 296.5 Moribund
210 42 100MG/KG 607 173.6 204.6 223.5 242.2 247.4 258.2 272.1 276.8 286.3 297 304.5 313.2 315.6 337.4 358.3 371.8 372.6 382.3 403 402 414 432.8 420 435.4 442.6 435.3 446.4 452.2 443.5 435.9 420.6 311.9 Moribund
211 43 100MG/KG 552 166.5 201.7 232.3 235.6 251.4 276.1 289.7 296 311.9 318.1 326.7 337.8 341.3 365.9 386.1 395.5 399 405.7 420.9 417.7 428.4 439.8 441 442.2 456.2 457.1 458.9 467.6 480.1 355 Dead
212 43 100MG/KG 572 139.1 179.4 207.6 211 225.4 242 259.4 268.5 275.5 286.1 298.9 308.1 309.4 331.8 349 368.1 379.6 388.5 410.5 412.7 420.6 430.9 428 432.8 439.2 439.7 443.7 452.1 458.3 356.6 308.9 Moribund
213 43 100MG/KG 533 182.5 213 236.9 255.1 259.3 278.4 290.4 295.1 302.5 312.7 325.2 329.8 332.3 358.1 376.5 394.5 401.7 418.2 431.3 430.4 435.8 441.9 436.1 451.9 460.1 456.6 464.3 468.1 327.2 Dead
214 43 100MG/KG 511 151.4 177.4 205.6 211.7 233.6 247.9 263.4 271.2 287.7 296 303.9 309.4 309 336.6 346 364.3 363.4 378.3 385 380.2 389.1 393.9 399.2 381.8 409.5 409 384.5 311.1|308.7 Moribund
215 43 100MG/KG 551 181.4 213.7 237.5 240.8 243.5 269.1 285.3 289.9 299.4 308.7 315.3 325.6 327.5 351.4 358.5 380.2 383.9 392.6 407.2 409.8 421.9 423.5 429.5 431.8 443 445.8 439.4 425.6 415.6 308.6 Dead
216 44 100MG/KG 453 176.6 214.8 250.1 264.5 282.8 300.1 315.5 322.5 331.7 338.6 346.8 352.5 344.6 382.6 406.7 412.9 419.9 436.3 458.5 461.4 477.3 487.7 489.4 504.7 505.2 514.8 Interval Sacrifice
217 44 100MG/KG 455 156.2 197.2 232.8 256.7 254.9 270 285.1 297.5 307 312.3 320.1 324.8 330.3 353.3 369.1 377.8 385.3 395.8 415.5 427.4 437.6 441.2 441.6 452.5 454.1 462.8 Interval Sacrifice
218 44 100MG/KG 654 158.3 183.7 215.2 232.6 238.6 254.6 271.1 278.4 290 297 307.2 310.7 311.3 336.6 353 360.5 369 380.6 393.9 398.3 405.4 414.8 422.6 435.6 435.5 441.7 449.2 444.1 443 445.7 420 414.1 347 310.5 Dead
219 44 100MG/KG 567 155.7 191.7 219.3 223.8 245.5 265 278.8 287.7 299.1 309 318 320.4 320 345.5 358.9 367.2 374.6 380 397.6 404.9 408 423.5 431.4 442.5 448.8 449.7 473.8 460.2 450 334.6 Dead
220 44 100MG/KG 307 177.5 214.1 249.7 262.4 279.9 294.6 310.2 311.7 324.4 332.8 338.8 342.8 344.5 368.9 385.4 397 396.8 412.7 424.2 416.2 375.2 Moribund
221 45 100MG/KG 453 170.4 200.4 230 253.6 267.7 280.9 294.4 300.8 308.3 318.5 325.6 331.9 329.5 356.7 371.5 372.5 373.2 376.5 400.2 410.4 409.7 420.8 433.1 426.1 444 456.1 Interval Sacrifice
222 45 100MG/KG 660 161.1 189.1 219.3 239.7 253.8 263 273.7 278.3 285.1 293 300.6 315.5 317.8 344.3 370.1 366.9 369.2 374 387.1 393.7 400.3 405 416.4 421.1 429.6 436.1 440.3 430.3 442.5 428.4 417.8 356.1 331.6 332.6 Moribund
223 45 100MG/KG 477 165.3 201.3 226.4 245.7 257.3 275.3 289.1 285 303 315.6 326.9 333.3 333.5 364.1 384.5 386.8 383.4 400.6 416.9 428.3 432.4 438 419.9 435.5 452.9 454.4 331.1 Dead
224 45 100MG/KG 492 164.5 206.4 240.4 257.6 275.7 290.8 301.6 309.2 325.4 341.3 348.2 355.8 355.3 383.8 392.6 388.9 382.8 409.3 421.5 433.5 436.4 455.8 458.6 447.4 459.9 465.5 424 333.9 Moribund
225 45 100MG/KG 512 143.2 168.7 195.2 206.2 224.8 240 254.6 256.1 270.1 281.7 294.1 297.2 286.5 324.6 343.6 345.2 350.3 364.5 375.8 382.8 392.4 398.9 394.6 402.1 414 417.9 407.2 343.7 331.1 Moribund
226 46 100MG/KG 455 182.6 216.7 251.1 263.9 278.9 295.3 306.6 302.6 320.8 329.9 342.6 349.2 344.7 374 391.2 412.7 422.4 432.6 455.6 460.4 457 474.6 486.8 489.8 500.7 494.3 Interval Sacrifice
227 46 100MG/KG 580 173.3 211.8 238.3 258.5 266.1 282.4 295.5 297.3 309.4 317.5 325.8 333.7 327.5 340.7 346.1 366.8 374.3 376.2 391.7 391.5 393.7 410.2 406.5 405 412 407.5 411.2 403 392.8 373 341.3 Moribund
228 46 100MG/KG 618 152.9 175.2 202 209.4 223.2 240.2 253.2 256.1 273.8 283.5 293.8 299.4 301.9 320.7 328.1 346 347.7 359.9 385.6 386 385.1 400.1 401.5 408 422.2 412.5 418.4 415.9 423.3 422.8 403.6 316.3 Dead
229 46 100MG/KG 517 171.2 204 234 254.6 265.6 281.5 294.3 294.4 309.2 320.1 331.5 338.7 342.4 372.4 373.4 406.9 410.8 408.6 440.5 446.4 447.6 460.8 468.8 463.3 476.1 474.6 480.6 385.3 325.4 Dead
230 46 100MG/KG 611 175.4 205.4 236.7 247.3 254.2 268.6 280.2 272.8 291.4 295 305.8 316.4 309.7 333.2 347.8 364.3 366.2 372.9 391.8 397.3 397.6 413.2 418.5 413.9 415 416.5 419.1 401.2 381.7 343.9 337.1 272 Moribund
231 47 100MG/KG 518 160.4 195.4 227.2 252.8 262.6 276.7 291.7 299.4 302.8 316 324.2 332.4 335.2 356.9 368.9 384 392.9 401.2 423.1 435.9 442.7 455.6 455.8 464.3 466.8 466.8 469 424 366.2 Moribund
232 47 100MG/KG 611 171.6 201.3 228.6 262.5 272.9 285.3 293.2 304.3 319.8 332.1 338.9 348.1 350.2 369.1 378.1 393.9 399.4 410.2 429.3 438.5 444 452.9 455.1 455.4 463.3 457.9 471.6 473 478.2 425.7 412.6 272 Moribund
233 47 100MG/KG 643 167.6 201.6 230.6 249.8 264.1 280.1 293.3 295.3 309 321.2 328.9 337.3 335.1 359.6 368 387.1 391.2 388.6 410.2 418.3 423.4 440 436.5 437.9 460.9 464.2 470.2 468.3 473.6 486.8 468.5 291.8 Moribund
234 47 100MG/KG 552 148.5 185.7 223.8 243.7 256.6 268.2 280.6 286.3 300.5 311.4 322.7 333.8 339.7 369.9 383.7 394.6 404.5 409.6 432.6 439.4 442.5 456.8 450.9 454.3 462.4 462.3 464.3 464.3 433.8 360.4 Dead
235 47 100MG/KG 566 186.6 217.1 243.7 265.3 270.8 286.4 296.9 299.7 310 322.5 330.1 339.3 334.4 354.7 368.5 379.8 390.9 398.8 420.5 425.1 429.2 445.8 445 440.7 448.5 446.1 444.7 445.1 440.6 298.6 Dead
236 48 100MG/KG 650 147.6 177.4 200.8 221.2 228.1 244.7 256.7 263.4 264 277.5 268 281.9 284 309.3 317.6 326.9 328.9 340.8 360.3 348.7 362.8 376.2 373.9 382.7 394.6 394.8 409.7 407.5 413.4 409.3 407.1 274.8 Moribund
237 48 100MG/KG 455 166.5 190.8 217.4 234.8 244.5 256.3 265.7 272.6 282.9 295.1 278.3 298 305.7 320.9 331.5 343.4 340.8 351.9 364.7 363.2 376 387.1 384.3 397.1 407.4 405.8 Interval Sacrifice
238 48 100MG/KG 638 168.8 204.7 234.3 252.6 277.2 292.9 306.1 310.8 313.3 324.6 312.1 329.8 339.4 370.3 375.4 385.9 397.6 408.4 424.9 420.9 432.6 439.2 430.8 442.9 447.3 450.5 454.5 457.6 446.8 429.7 413.6 279.6 Moribund
239 48 100MG/KG 646 156.2 184.8 212.4 235 237.5 256.2 273.4 279.4 289.7 300.9 283 298 312.2 334.7 346 355.1 364.8 379.2 392 391.2 397.2 409.3 404.8 414.7 417.3 424.3 432.8 437.4 429.9 424.9 426.7 293.3 Moribund
240 48 100MG/KG 456 163.5 198.4 227.9 261.1 269 281.9 297.6 305.2 316 331.7 319 336.5 344.8 368.9 380.1 397.6 405.6 423.2 441.8 442.4 463.5 468.5 469.4 470.6 475.6 471.8 474.5 Interval Sacrifice
241 49 Vehicle Control 275 184.8 213.6 251.3 264.6 273.5 289.7 300.2 309.4 321.4 333.1 338.3 348.8 353 382.2 387.1 405.8 424.6 441.9 463.1 457.1 Interval Sacrifice
242 49 Vehicle Control 274 187.6 212.8 240.8 266.8 274.8 293.7 306.9 321.2 330.5 342.9 344.5 354.5 358 388.3 396.9 411.9 426.6 439.5 453.3 448 Interval Sacrifice
243 49 Vehicle Control 274 147.1 172.6 206.6 230.3 247.1 269.7 281.1 298.1 311.9 326.3 330.7 338.3 344.4 372.6 390.8 418.8 439.6 452.6 470.9 432.3 Interval Sacrifice
244 49 Vehicle Control 274 199 233.3 270.4 298.9 310.9 335.8 342.4 351.8 365.6 377.4 382.3 391 393.4 420.9 437.5 438.1 461.2 474.1 500.4 464.4 Interval Sacrifice
245 49 Vehicle Control 216 184.2 208.1 244.9 270.3 275.2 299.4 308.1 316.3 340.7 355.9 356.7 370.8 376.8 410.2 416.7 441 440.9 447 Dead
246 50 Vehicle Control 274 173.4 204.5 235.4 265.6 276.3 292.6 306.8 318.6 322.4 335.2 336.4 348.8 355.1 377.7 394.3 404.4 423.9 444.7 457.2 383 Interval Sacrifice
247 50 Vehicle Control 274 184.1 213.8 236.7 273.3 283.9 303.2 318.7 334.9 347.6 359.4 359.8 371.7 381.2 407.7 416.7 433.9 457.2 474.8 471.9 453.2 Interval Sacrifice
248 50 Vehicle Control 70 171.7 205.6 237.3 273.5 288.3 307.6 324.5 340.2 353.8 366.2|362.4 Gavage Death
249 50 Vehicle Control 275 222.8 247.1 280.3 296.5 313.7 332.5 342.3 351.3 364.3 379.2 380.4 394.2 398.9 428.6 425.2 439.3 460.7 473.4 487.7 489.4 Interval Sacrifice
250 50 Vehicle Control 274 178.2 202.8 231.6 256.1 269.7 286.6 301.7 301.2 309.5 321.2 317.9 331.6 340.9 368.1 382.2 388.9 406.9 419.9 431.5 427 Interval Sacrifice
251 51 Vehicle Control 275 196.5 226.2 256.1 272.1 273 292.4 302.7 315.8 319.8 327 325.3 340 347.9 378.5 389.6 407.2 426.5 428.8 444.5 452.9 Interval Sacrifice
252 51 Vehicle Control 275 216 241.7 270.4 302.4 305.4 319.8 328.4 341.2 339.6 348.5 348.2 362.3 367.6 395.3 411 417.4 435.4 441.1 460.6 468.3 Interval Sacrifice
253 51 Vehicle Control 274 195.5 233.8 272.6 296.9 307.8 319.5 325.2 339.4 343.4 357.9 360.5 378.4 383.5 413.4 422.2 429.9 450.9 453.1 480 479.5 Interval Sacrifice
254 51 Vehicle Control 274 194.4 230.8 259 293.4 302.8 325.4 346.2 359.9 364.8 375.6 376.6 390.9 397.1 429.2 442.5 456.5 470.7 479.3 480.8 485.7 Interval Sacrifice
255 51 Vehicle Control 275 166.9 198.8 226 261 272.9 289.5 299.2 311 315.3 326.1 325.4 338.7 345.5 380.1 395.1 409.4 432.2 435 460.7 463.2 Interval Sacrifice
256 52 Vehicle Control 274 226.2 261.1 292 305 331.9 344.3 352.2 357.2 367.8 379.6 383.4 398.8 400.7 428 448 470.6 479.4 493 512.8 516.5 Interval Sacrifice
257 52 Vehicle Control 274 155.6 184.4 213.8 288 260.7 274.3 285.4 299.7 312.1 327.2 327.4 338.2 349.5 377.1 378.8 406.5 413.6 436.5 458.1 453.1 Interval Sacrifice
258 52 Vehicle Control 50 204.4 233.8 262.3 286.4 304.5 321 324.9 324.9 Gavage Death
259 52 Vehicle Control 275 179.1 215.9 249.4 262.1 279 295.5 306.4 301.7 313.5 321.5 330 344.2 354.4 389.1 401.4 419.1 441.7 465 482.8 457.4 Interval Sacrifice
260 52 Vehicle Control 275 169.7 194 218.4 236.8 249.6 268.6 283.3 291.2 302.5 313 319.6 329.6 342.5 370.6 386.8 418.9 438.7 455.3 481.2 482.5 Interval Sacrifice
261 53 100MG/KG 275 144.9 163.5 191.2 198.1 222 237.5 255.6 265.3 272.1 282.2 289.3 304 313.8 336.1 348 357.5 355.4 373.9 391 389 Interval Sacrifice
262 53 100MG/KG 275 164 198.3 228.8 253.7 266.4 281 292.1 302 309.7 318.6 325.4 331.3 337.8 355.2 369.1 378.8 377.7 396.9 406.9 401.3 Interval Sacrifice
263 53 100MG/KG 274 173.7 201 230.8 253.1 267.5 282.2 292.1 294.2 290.6 302.9 310.2 317.7 324.9 350.6 365.5 364.1 357.8 374.4 395 322.5 Interval Sacrifice
264 53 100MG/KG 275 164.2 193.9 217.3 242.6 258.3 272.2 281 287.7 289.6 297.9 306.4 318.2 324.8 346.4 355.8 372.9 376.3 384.3 393.7 395.2 Interval Sacrifice
265 53 100MG/KG 274 154.4 181.3 206.5 219.8 240.3 251.4 264.2 274.8 276.7 287.9 290.9 298.8 307 322.9 335.5 342.9 325.8 341.1 353.4 332 Interval Sacrifice
266 54 100MG/KG 274 175.9 198.2 220.3 245.2 263.1 275.5 285.8 293.2 297.7 312 310.7 320.3 323.4 351 362 372.5 379.1 392.9 398.6 395.9 Interval Sacrifice
267 54 100MG/KG 275 165.2 193.5 223.7 246.6 264 278.8 282.9 287.1 286.4 297.3 299.3 315.3 322.2 339.6 348.4 356.7 369.7 384.4 390.2 393 Interval Sacrifice
268 54 100MG/KG 20 167.1 191.2 214.1 Gavage Death
269 54 100MG/KG 274 163.2 198.5 217.5 242 258.2 278.7 294.3 303.7 315.6 332.7 331.7 337.4 345 372.7 387.9 403.2 416.2 435.8 450.8 422.3 Interval Sacrifice
270 54 100MG/KG 274 162.2 194.6 208 230.3 244.3 255.1 260.1 266.2 272 287.1 287.7 299.3 302.7 323 331.8 340.6 343.4 359.7 367.5 361.5 Interval Sacrifice
271 55 100MG/KG 274 177.9 202.4 228.3 254.3 270.2 286.7 303.2 308.2 313.4 329.2 336.7 344.8 349 363.2 390.4 406.1 415.7 427.1 443.2 424 Interval Sacrifice
272 55 100MG/KG 275 165.2 193.7 216.8 249 258.5 276.4 287.1 298.2 305.7 316.3 323.7 330.9 340.8 367.9 388 391.8 402.1 417.2 425 426 Interval Sacrifice
273 55 100MG/KG 83 147.4 184.6 201.5 233.3 246.3 265.9 277.9 286.5 293.5 303.6 308.1 318.1 Gavage Death
274 55 100MG/KG 275 188.9 220.5 246.4 270.3 285.2 300.2 314.1 309.9 314.4 320.2 330.4 344.9 346.9 373.6 391.7 409.4 412.9 418.3 437.1 433.6 Interval Sacrifice
275 55 100MG/KG 275 179.7 193.1 223.7 238.3 257.9 274.9 282.4 283.4 287.6 298.7 307.3 324.1 332.4 357.2 366.8 384.1 395.7 394.7 415.5 416.1 Interval Sacrifice
276 56 100MG/KG 275 181.9 200.5 222.5 251.5 266.2 281.6 290 294.8 304.8 309.3 315.7 325.5 337.1 361.4 360.1 381.5 389.3 401.8 421.8 427 Interval Sacrifice
277 56 100MG/KG 274 162.3 186.1 218.1 244.5 256.5 273.6 280.6 284 290.5 296.5 299.9 317.2 320.6 342.6 338.7 350.1 347 366.8 378.3 370.9 Interval Sacrifice
278 56 100MG/KG 274 161.8 189.4 207.1 243.6 245.6 259.6 268.7 271.4 280.6 291.8 297.3 303.5 319.1 338.4 341.1 363.7 356.6 368.1 376.2 375 Interval Sacrifice
279 56 100MG/KG 275 170.1 198.8 225.7 254.9 271.8 292.3 304.1 307.2 320 329.9 337.5 344.4 350.4 374.2 376.1 393.6 408.4 425.4 438.3 442.8 Interval Sacrifice
280 56 100MG/KG 275 167.3 195.3 217.4 249.6 253.7 271.8 282.1 289.4 290.3 300.8 312.6 327.2 337.2 359.5 362.1 382.7 375 390 401.8 405.3 Interval Sacrifice
281 57 100MG/KG 729 170.5 207.1 224.8 250.8 262.6 280.9 293.5 289.8 304.2 318.4 326.6 332.1 339.4 356.2 368.4 393.3 396.1 406.7 422.8 421.4 427.4 446.6 450 467 471.1 470.7 478.8 480.6 482.8 467.4 466.9 467.5 461 447.8 430.6 373.9 300.6 Terminal Sacrifice
282 57 100MG/KG 618 172.7 191.9 220.6 232.9 255.8 268.3 276.7 279.3 292.6 303.5 309 317.5 323.2 337 350.4 373.7 372.8 387.5 403.5 405.2 413.2 430.8 433.4 446.2 465.7 464.5 473.4 470.1 476.6 461.6 393 257.5 Moribund
283 57 100MG/KG 729 161.7 192.6 220.3 249.4 268.1 284 292.3 294.7 307.5 313.5 321.1 333.2 340 347.7 358.6 383 383.9 395 409.6 423.6 424.6 451.5 448 461.2 477.4 467.8 482.8 491.4 497.7 490.9 492 483.2 482 472.4 464.8 408.1 335.4 Terminal Sacrifice
284 57 100MG/KG 729 151.7 175.2 194.4 220.2 233.8 249.9 258.9 270 283.5 286.2 294.7 304.8 314.3 328.1 343.7 363.3 365.1 373.1 384.7 384.1 394.4 409.8 409.7 427.9 436.4 435.8 442.7 453.8 446.9 441.6 434.2 425.8 418.1 407.4 399.6 399.4 403.3 Terminal Sacrifice
285 57 100MG/KG 730 174 200.6 227 248.9 258.5 279.2 287.1 292 304.1 312.6 316.1 326 335.3 357.4 358.6 381.2 385.2 390 407.5 404.8 415.8 432.8 442 449.3 460 463.4 468.1 468 469.6 474.5 468.4 456.4 456.1 449.3 447.1 445.6 434.4 Terminal Sacrifice
286 58 100MG/KG 583 174.6 199.4 219.6 243.5 257.2 269 271.8 276.1 285.5 296.3 303 314.6 317.5 322.6 335.7 357.2 359.1 369.4 381.3 380.6 390.5 393.7 409.9 417.1 425.5 418.6 425.4 432.7 413.9 408.4 411.3 Dead
287 58 100MG/KG 520 174.7 205.9 220.5 242.3 264 278.4 286.9 294.6 299.2 310.4 318.1 328.4 335.9 354.9 370.9 386.3 394 407.7 415.7 409.8 428 433.2 453.4 460.9 469.1 447 454.4 385.1 314.8 Moribund
288 58 100MG/KG 730 186.1 207.2 230.9 249.5 267.9 281.6 289.8 293 298.5 310 317.8 330.2 328 342.5 356.8 379.6 388.5 395.6 407 399.3 419.5 426.8 443.8 453.3 462.8 455 460.9 461.5 451 444.1 434.6 435 435.3 417.5 407.2 401.8 401.1 Terminal Sacrifice
289 58 100MG/KG 680 169.6 198.2 223.7 245.4 259.4 275 283.4 290.7 295.8 303.3 310.2 319.8 322.9 342.9 358.6 378.2 386.1 396.1 406.1 401.7 425.1 427.8 453.3 470.7 485.4 476.6 493.2 497.8 494 490.2 477.7 461.3 438.8 324.8 313.5 Moribund
290 58 100MG/KG 307 164.9 193.8 206.7 244.2 250.8 262.3 274 279.5 284 296.9 306.6 314.1 320.7 329.6 347.5 358.8 354.3 372.8 375.6 367 281.1 Dead
291 59 100MG/KG 619 189.6 216.5 243.1 270.5 284.8 298.3 306.1 317.1 323.6 338.5 345 348.1 357.5 374.9 389.9 410.4 408.7 428.6 441.1 442.2 454.2 466.9 472.5 490.3 479.2 479.2 482.8 482.3 479 468.9 464.1 369 Dead
292 59 100MG/KG 688 173.7 197.3 221.2 242.6 250.1 260.2 268.6 276 277.1 287.5 291.3 298 304.3 307.9 321.8 332.8 325.6 325.7 342.3 342.8 353.2 359.3 375.1 388 393.2 392.4 399.5 399.4 395.5 392.2 379.6 383.9 376.7 325.8 259.6 Moribund
293 59 100MG/KG 588 151.2 172.2 202.1 230.1 242.4 252.9 259.4 270.9 277.4 289.3 293.5 301.4 307.8 317.8 332 358 365 374.1 392.6 389.4 411.9 416.1 431.9 437.9 440.4 431.1 439.2 434.1 441.5 406.3 307.5 Dead
294 59 100MG/KG 49 158.6 189 208.7 242.7 249.8 264 269.7|269.8 Gavage Death
295 59 100MG/KG 680 176.2 214.8 242.1 265.3 277.4 293.2 302.7 310.7 316.5 327.2 333.5 339.5 348.1 368.6 374.8 404.5 407.4 421 442.1 429.8 448.8 453.9 469 473.4 470.9 473.6 482.2 482.6 481.3 479.1 462.3 393.4 378.8 235.2 228.7 Moribund
296 60 100MG/KG 729 181.5 205.5 233.6 265 275.4 290 305.6 309.1 316.6 327.2 333.5 339.4 344.4 366.7 374.2 395.5 407.1 425.1 437.3 440.8 445.2 457.7 478.7 492.1 489.7 494.1 499.7 507.3 526.2 520.3 510.1 502.4 485.6 443.7 405.8 394.3 368.6 Terminal Sacrifice
297 60 100MG/KG 729 178.6 209.7 236.5 256.8 267.8 285.1 292.7 296.1 302.9 316.3 318.5 321.5 323.4 347.1 379.6 370.7 387.8 399.6 406.3 408 412.9 423.7 451.9 464.3 465.3 474.8 470.4 469.3 473.5 463.1 463.6 461.2 462.3 455.7 438.6 382.5 339.1 Dead
298 60 100MG/KG 680 167.9 197.5 222.5 243.8 259.9 274.9 284.7 292.1 296.4 306.2 313.8 316.2 328.4 343.2 349.5 366.5 368.9 382.5 391 396.7 405.4 414.8 430.8 440.3 438.2 440.5 444.3 447.5 449.9 425.7 408.8 395.1 377.6 287.2 282 Moribund
299 60 100MG/KG 729 185.9 211.5 238.8 260.1 271.8 282 294.6 298.5 300.9 307.9 312.8 324.4 329.1 339 348.3 362.7 365.5 387.4 401.6 407.8 409.9 418.3 437.3 452.9 459.4 463.5 458.1 462.3 466.6 451.6 451.7 453.7 442.1 415.6 415 427.1 421.9 Terminal Sacrifice
300 60 100MG/KG 729 171.6 195.4 212.5 235.3 251 266.5 277.3 281 289.7 302.9 307.8 316.7 323.7 351.3 372.6 381.7 402.9 404 420.5 427.6 436.5 445.7 467.6 477.1 475.7 478.1 480.9 476.3 478.3 464.1 457.5 448.6 441.4 416.2 399.6 379.4 360.9 Terminal Sacrifice
301 61 Vehicle Control 337 197.2 228.3 256.3 288.5 299.5 315.6 327.8 336.7 343.9 353.2 356 367.6 373.3 402.1 414.5 443.3 459.2 477.8 493.4 506.4 510.7 530.2 Gavage Death
302 61 Vehicle Control 453 178.9 203.6 236.7 261.3 273.6 288.5 305 302.7 315.3 329.1 335 351 356.9 381.6 385.3 404.7 432.1 444.4 460.2 469.5 473.3 492.9 502 513.3 515.8 523.6 Interval Sacrifice
303 61 Vehicle Control 338 171.5 204.5 246.5 277 292.9 305.5 324.9 343.2 352.8 363.9 364.9 380.3 390.6 415.5 422.9 443.6 464.7 475.4 496.5 496.2 508.5 507.5 Gavage Death
304 61 Vehicle Control 455 170.5 200.8 237.3 262.4 285.6 300.9 312.4 328.6 340.2 348.3 350.5 364.6 371.6 403 410.6 435.4 450.6 461.9 473.3 485.4 484.9 497.9 503.1 513.8 518.6 532.3 Interval Sacrifice
305 61 Vehicle Control 456 171.5 200 229.4 248.9 267.2 282.2 296.3 313.5 324.5 334.7 333.9 345.7 356.8 382.4 391.4 413.7 432.8 450.7 453.3 467.1 479.3 494.8 493 505.5 514.2 515.9 521.4 Interval Sacrifice
306 62 Vehicle Control 455 162.4 197 226 249.1 281.5 297.7 310.3 324.8 336.3 338.9 348.6 353.9 387.2 411.1 437.6 442.3 457.7 464.5 462.4 467.9 483 495.6 504.3 503.4 521.4 Interval Sacrifice
307 62 Vehicle Control 71 179.5 208.2 234.6 253.5 286.6 295.1 309.2 327.3 341.8 331.4 Gavage Death
308 62 Vehicle Control 455 179.6 213.9 234.8 263.5 298.4 309.5 326.3 340 356 357.5 368.7 355.3 396.3 406.4 424.8 440.7 461 477.3 478.4 489.8 502.6 510.1 512.2 533.5 538.6 Interval Sacrifice
309 62 Vehicle Control 453 161.4 189.5 215.6 249.2 279 295.2 306.4 325.5 340.5 345.1 356 360.9 387.8 405.7 440.3 448.4 467.6 485.8 493.1 502.1 510.2 522.4 532.9 540.6 534.3 Interval Sacrifice
310 62 Vehicle Control 455 169.5 203.9 230.6 256.6 283.4 296.8 308.6 326 340.4 342.3 352.2 329.3 381.4 392.2 426.2 444.3 464.4 483.9 488.4 470.8 500.7 507.6 520.7 536.7 534 Interval Sacrifice
311 63 100MG/KG 455 187.2 208.4 220.7 238.1 255.1 265.1 272.7 281.6 291.4 301.6 310 315.7 325 342.3 354.2 360.3 366.3 359.5 384.3 389.2 401.6 413.6 423.4 420.8 422.7 429.7 Interval Sacrifice
312 63 100MG/KG 455 178.7 202.9 233.9 261.9 277.2 295.5 308.7 319.1 325.3 323.2 336.7 346.8 356.9 367.1 378.4 395 412 399.6 418.8 434.3 439.6 447.5 453.9 460.3 461.9 463.2 Interval Sacrifice
313 63 100MG/KG 453 181.7 208.9 220.9 244.9 256.5 270.1 278.9 287.8 298.1 310 317.3 324.7 335.2 355.3 359.1 376.2 381.7 378.4 408.2 400.4 415 417.6 428.5 424.9 423.4 429.2 Interval Sacrifice
314 63 100MG/KG 453 165.1 192.8 223.1 249.8 260.3 279.3 291.1 300.2 309.2 320 320.5 336.7 348 367.9 374.5 388.2 402.7 405.6 427.7 423.1 443.1 450.8 462.2 472 478.3 490.5 Interval Sacrifice
315 63 100MG/KG 456 167.1 203.5 226.6 274.6 263.8 278.3 286.7 291.8 302 311 313 321.5 333.8 346.9 362.6 367.6 381.3 380.8 400.9 413.6 406.2 413.2 425.3 430.8 428.7 430.5 432.6 Interval Sacrifice
316 64 100MG/KG 456 184.1 216.2 240.9 262.9 280.2 300.3 306.4 308 318.3 328.9 336.3 347.8 353.3 375.9 377.9 405.9 408.3 419.7 438.8 434.6 444.6 457.3 462.9 468.1 477.5 482.8 491.5 Interval Sacrifice
317 64 100MG/KG 456 215.1 237.6 260.1 275 292.1 306.8 316.3 315.6 323.2 328.3 332.2 344.2 353.6 365.1 367 391.4 390.7 392.7 412.2 413.4 425.6 432.7 439.6 433 440.3 451.7 454.2 Interval Sacrifice
318 64 100MG/KG 455 191.9 221.6 244.2 258.6 273.1 289.4 295.1 298.8 304.2 314.3 322.4 336.6 338.7 367.4 379.2 404.1 412.3 426.2 443.3 442.6 447 452.8 459.2 458 458.2 514.8 Interval Sacrifice
319 64 100MG/KG 453 168.4 200.7 227 249.8 264 276.6 283.5 288.4 299.8 307.7 319.7 332.9 343.5 369.1 374.1 395 399 398.1 423.5 426.5 434.4 441.9 447.8 455.5 445.6 461.6 Interval Sacrifice
320 64 100MG/KG 455 195.8 223.1 244 262.3 271.7 289.2 295.3 296.2 301.2 309.3 319.5 329.2 338.4 356.3 357.7 379.9 384.5 401.3 412.4 411.2 426.3 434.3 429 433.9 442.2 450.6 Interval Sacrifice
321 65 100MG/KG 565 168.8 197.1 213.3 239.3 254 275.4 288.9 297.1 302.7 318.9 320.3 320.1 331.5 350.6 366 397 401.3 408.4 428.5 417.8 437.2 453.4 408.4 423 429.6 435.2 442.3 437.9 421.5 302.3 Moribund
322 65 100MG/KG 729 158.1 184.9 212.2 248 261.1 280.4 296.2 302.5 310.9 319 325.8 333.9 342.7 359 364.6 381.8 395.5 405.6 428.6 425.4 432.3 447.6 443.2 456.4 458.7 464.3 478.8 476.3 476.5 458.8 455.7 449.6 440.2 431.1 395.4 351.4 298.2 Terminal Sacrifice
323 65 100MG/KG 639 163.8 185.4 211.9 231.5 247.7 264.8 276.9 284.9 293.2 305.7 315.1 322.8 330.1 352.3 358.3 379.2 382.4 395 413.6 413.6 422 436.1 428.5 441.3 445.7 447.4 458.4 458.8 457.1 444.1 440.9 419.1 328.4 Moribund
324 65 100MG/KG 40 184.5 217.4 238.2 261.8 283.4 298.2 Gavage Death
325 65 100MG/KG 566 157 191.5 217.2 248.2 260.2 279.7 288.9 293.8 296.2 308.7 315.7 334 340.1 355.9 368.2 390.3 389 393.8 418.8 411.1 422.9 437.3 431.6 430.8 413.7 422.3 416 419.7 414.2 318.5 Moribund
326 66 100MG/KG 726 177.5 213.1 241.6 265.6 290.2 295.9 306.1 309.5 319.2 334.9 341.3 345.7 359 380.8 391.5 407 422.7 427.3 444.8 442 457.4 476.3 469.8 488.7 486.4 497.2 517 521 515.5 522.1 517.6 507.9 416.8 401.8 322.3 306.2 269.3 Dead
327 66 100MG/KG 639 185.4 211.5 230 257.9 266.8 283.6 292.3 292.6 300.6 313.4 319.5 325.5 334 343.3 353.1 362.8 372.4 383.8 389.7 388.7 398.4 411.4 412.6 420.4 429.4 430.8 448.6 460.2 453.4 450.9 435.3 420.9 278.7 Moribund
328 66 100MG/KG 623 171.2 203.7 225.3 248.1 267.2 281.2 294.2 300.7 315.5 323.8 328.8 333.5 346.7 354.6 367.2 370.2 397.1 402.7 419.6 420.7 433.9 442.8 437.3 449.8 449.1 449.9 472.4 477.6 456.8 454.8 448.7 371.8 Dead
329 66 100MG/KG 729 181.7 212.9 239.9 261.7 274 284.5 294 294.7 304.2 316 323.2 335.5 337 337.1 340.6 359.7 375.7 381.5 392.1 400.3 408.2 418.4 412.6 423.2 422.4 421.5 439 447.4 452.8 457 456.1 459.5 466.7 460.6 451.6 439.6 346.3 Terminal Sacrifice
330 66 100MG/KG 609 164 192.1 214.2 227.3 245.5 255.4 263.9 266 278.3 286.2 288.5 303.2 311 330.1 334.5 343.2 363.1 365.4 379.2 376 381.9 397.9 387.7 403 402.7 397.5 423.2 425.9 423.5 414.7 393.4 302.8 Moribund
331 67 100MG/KG 618 157.3 189.8 220.5 242.3 257.2 271 281.6 289.6 300.4 307.2 314.9 321.6 330.5 358 377.1 389.8 393 390.8 416.9 418.8 429.4 442.9 444.3 455.6 448.5 457.8 471.8 470 464.1 411.2 427.2 315.7 Moribund
332 67 100MG/KG 593 185.4 216.1 242.3 265.1 278.1 295 299.7 307 315.1 326.1 330.6 338.4 351.3 363.6 373.1 396.6 396.9 400.1 417.8 424.6 433.2 442.6 447.4 457 460.2 451.5 460.2 460.8 460 397.1 324.1 Moribund
333 67 100MG/KG 496 165 204.8 234.1 258.9 264.9 279.3 283.7 287.4 304.1 318.3 325.6 332.8 341.6 371 387.8 410.2 415.9 414.4 433.5 439.5 445.4 462.8 453.8 464.6 465.4 464.4 462.3 326 Moribund
334 67 100MG/KG 499 172.4 205 230.8 247.5 266.9 282.7 290.2 293.9 306.6 320.3 328.8 338.8 346.7 372 392.1 403.7 414.5 417.5 438.7 447.7 447.7 452.4 453 472 469.3 463.4 448 349.9 Moribund
335 67 100MG/KG 618 159.6 195.4 234.4 259.1 272.5 290.5 301.8 309.6 322.5 330.9 337.2 342.7 348.8 360.3 382 396.7 392.2 389.7 411.7 415.5 426.9 437.9 432.3 447 448.1 454.8 469.4 469.2 462.4 414.9 442.9 290.9 Moribund
336 68 100MG/KG 70 174.6 200.6 216 242.6 260 274 282.5 287.4 297.2 305.1|302.1 Gavage Death
337 68 100MG/KG 585 158 193.4 221.3 256.3 260.5 270.4 282.9 288.7 295.8 306.8 312.5 312.1 325.1 337.4 356.6 381.5 385.4 385.5 404.1 410.1 414.2 427.4 433.2 442 445.8 445.1 440.2 425.9 431.9 347.6 262.5 Moribund
338 68 100MG/KG 588 187.7 211.4 231.6 252.5 264.9 278.7 289.5 293.8 302.6 313.6 319.4 326 336.3 344.7 360.9 378.9 380.5 390 397.9 403.6 407 410.7 419.5 423.1 423.8 429.4 444.9 438.6 435 330.3 289.4 Moribund
339 68 100MG/KG 40 181.4 208.8 233 248.1 265.5 276.7 Gavage Death
340 68 100MG/KG 253 179.2 199.6 228.7 257.7 264 280.5 290 295.4 302.7 312.1 318.7 329.4 339 349.5 363.6 383.7 393.8 391.3 372 Moribund
* All body weights in grams