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Short-Term Study Body Weights

Study Information:

Chemical Name: Isobutyl nitrite
CASRN: ="542-56-3"
Study Number: C61052B
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0518501
Sex: Female
Strain and Species: F 344/N Rats

Table Instructions and Notes:
Multiple body weights in a single week are displayed in one cell separated by "|". Values displayed may not match report summary values due to individual values being excluded in some cases.
Animal Number Cage Number Dose Group Days On Study Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 13 Removal Reason
11 11 Vehicle Control 91 77.5 94 111.4 128.4 140.1 151.2 159.2 166.8 173.3 178.8 181.7|188 190.3|192.9 Terminal Sacrifice
12 12 Vehicle Control 91 85.4 103.8 123.2 132.4 145.2 159.1 166 173.5 180 179.2 186.6|193.2 194.4|196 Terminal Sacrifice
13 13 Vehicle Control 91 84.6 96.3 112.2 126 138.2 145.7 152.4 159.2 161.5 166.8 170.4|175.8 179.6|178 Terminal Sacrifice
14 14 Vehicle Control 91 85.9 102.4 117.4 131 140.3 147.7 155.1 159.4 160.4 168.1 166.5|174.9 173.9|176.9 Terminal Sacrifice
15 15 Vehicle Control 91 91.4 110.4 127.7 145.4 156.7 169.7 179.1 180.4 185.1 188.1 186.8|192.1 191.9|196.1 Terminal Sacrifice
16 16 Vehicle Control 91 92.6 112.5 131.1 145.8 157 164.5 169.8 171.6 174.1 176.3 181.4|184.3 185|186.8 Terminal Sacrifice
17 17 Vehicle Control 91 90.7 110.8 126.2 138.6 146.7 150.2 157.6 163.8 164.2 163.5 165.6|174.4 170.2|176.1 Terminal Sacrifice
18 18 Vehicle Control 91 102.5 120.4 135.1 156.8 170.1 180.9 188.9 195.7 203.1 208.2 213.5|221.4 230.4|233 Terminal Sacrifice
19 19 Vehicle Control 91 99.7 116.8 129.8 143.5 150.5 159.1 172 181.2 191.5 195.2 193.7|200.6 197.9|203.3 Terminal Sacrifice
20 20 Vehicle Control 91 109.6 126.2 141.5 151.8 162.3 170.5 179.7 183.4 188.2 194.1 194.4|199.8 201.5|202.4 Terminal Sacrifice
31 31 10PPM 91 79.5 97.6 113.2 126.8 138 145.1 153.3 157 161.9 168.2 169|175.3 176.9|177 Terminal Sacrifice
32 32 10PPM 91 84.8 101.6 121.8 136.3 148.9 159.6 167.3 174.7 178.9 181.2 185.7|189.2 191|193.6 Terminal Sacrifice
33 33 10PPM 91 83.8 100.4 112 127.4 137.5 148.9 153.5 160.8 163.6 170 175.3|178.4 181.4|184.2 Terminal Sacrifice
34 34 10PPM 91 85.9 105.5 122.1 137.3 148.7 160.1 167.4 171.9 173.2 179.7 183.6|188.3 190.1|190.6 Terminal Sacrifice
35 35 10PPM 91 87.5 107.3 124.6 139.6 154.2 160 168.7 173.9 175.3 185.2 190.5|197.1 193.1|195.4 Terminal Sacrifice
36 36 10PPM 91 90.4 111.2 128.9 144.5 156.2 168.7 177.8 181.4 188.7 195.2 199.3|203.6 209.9|214.4 Terminal Sacrifice
37 37 10PPM 91 90.7 110.5 129.4 147.6 154.8 163.5 170.3 176.6 185.6 188.8 191.2|197 198.3|194.3 Terminal Sacrifice
38 38 10PPM 91 96.5 112.7 131.3 144 151.8 166.6 171.1 180.6 187 191 195.8|196.1 202.4|202.8 Terminal Sacrifice
39 39 10PPM 91 98.4 114.1 135.3 151.7 161 170.1 176 180.2 192.1 196.7 201.6|205.6 204.5|204.6 Terminal Sacrifice
40 40 10PPM 91 102.2 118.9 136.5 153.4 165.1 170.7 175.7 181.7 189.8 195.7 202.3|207.6 206.5|208 Terminal Sacrifice
51 51 25PPM 91 79.8 94.4 111.3 128.8 139.3 146.5 154.4 161.4 163.8 166.4 171.3|170.5 175.6|174.6 Terminal Sacrifice
52 52 25PPM 91 80.3 104.5 121.1 137.2 146 159.4 166.2 171.6 172.1 185 188.1|195.3 199.2|202.6 Terminal Sacrifice
53 53 25PPM 91 79.7 101.9 121.2 136 152.9 161.7 170 175.1 177.9 188.9 191.9|194.1 202.8|201.9 Terminal Sacrifice
54 54 25PPM 91 87.8 103.3 125 137.7 150.5 159.8 167.4 173.3 175.3 187 189|191.5 200.1|197.4 Terminal Sacrifice
55 55 25PPM 91 89.5 107.5 123.4 136.3 148.8 156 165.9 172 175.8 177.4 183.3|188.7 191.7|194.1 Terminal Sacrifice
56 56 25PPM 91 90.1 105.7 120.4 132.4 147.4 152.3 157.2 162.2 169.6 174.1 179.1|180.1 183.7|190.7 Terminal Sacrifice
57 57 25PPM 91 93.6 113.1 133.2 149.5 159 171.5 183.3 190.3 192.5 202.6 210.1|212.7 213.4|215.4 Terminal Sacrifice
58 58 25PPM 91 94.4 115.7 137 153.7 166.6 182.8 185.9 192.5 201.3 206.3 210.7|211.9 215.9|214.4 Terminal Sacrifice
59 59 25PPM 91 100.8 113 129 138.4 149.5 157.2 168.9 169.8 172.2 175.8 180|186.2 190.8|189.7 Terminal Sacrifice
60 60 25PPM 91 106.5 121.6 137.8 147.7 159.6 172.3 182 187.9 196.5 205.7 210.6|211.6 206.6|217.1 Terminal Sacrifice
71 71 75PPM 91 76.1 93.4 109.6 122.5 135.5 144.8 145.5 151.8 153.9 158.6 162.3|163.9 167.7|169.4 Terminal Sacrifice
72 72 75PPM 91 76.2 98.3 119.4 137.2 146.9 160.6 167 172.9 178.3 186.1 185.9|190.1 194.7|193.4 Terminal Sacrifice
73 73 75PPM 91 83.2 100 116.3 131 143.7 149.7 157.2 163.2 167.6 173 173.9|177.9 179.2|176.1 Terminal Sacrifice
74 74 75PPM 91 85.8 102.4 119.8 133.2 144.9 153.8 162.6 168.1 171.2 177.8 184.1|186.9 194.2|196.3 Terminal Sacrifice
75 75 75PPM 91 87.9 104.2 122.8 132.8 144.2 154.2 160.4 167.6 173 177 179.7|180.5 186.3|187.4 Terminal Sacrifice
76 76 75PPM 91 88.3 105.7 124.4 137.9 145.8 156.6 165.1 168.2 173.1 182.4 189.6|191.2 198.5|198.4 Terminal Sacrifice
77 77 75PPM 91 93.5 110.7 126.7 139.5 151.4 157.1 163 168.5 172 182.5 186.1|188.2 186.4|186.1 Terminal Sacrifice
78 78 75PPM 91 95.2 111.6 127.1 144.3 156.7 164.2 170.7 176.6 181.3 185.7 190.5|195.6 198.2|198.3 Terminal Sacrifice
79 79 75PPM 91 96.4 117.7 137.7 151.8 168.9 179.6 185.2 197.2 204.3 208.4 211.4|215.2 223.6|222 Terminal Sacrifice
80 80 75PPM 91 104 124.5 142.5 156.4 167.9 173.1 181.4 187.5 194.7 197.4 202.9|206.9 206.2|212 Terminal Sacrifice
91 91 150PPM 91 78.8 93.6 109.2 123 130 135.2 147.7 149 154.1 150.5 159.7|163.9 164.1|167.6 Terminal Sacrifice
92 92 150PPM 91 78.4 95.2 115.4 127.3 139.2 148.8 156.7 160 165.2 166.1 173.4|175.3 178.7|183.1 Terminal Sacrifice
93 93 150PPM 91 82.5 99.3 117.3 128.4 142.6 146.1 150.7 155.2 163.2 162.4 168.1|170.2 171.6|179 Terminal Sacrifice
94 94 150PPM 91 85.7 101.3 119.3 131.7 141.4 151.4 157.7 153.4 164.4 167.5 174.3|176.1 178.2|184.6 Terminal Sacrifice
95 95 150PPM 91 87.9 101.3 117.6 129.8 137.1 146.8 152 157.5 159.2 161.7 171|173.3 173|176.3 Terminal Sacrifice
96 96 150PPM 91 92 105.8 124.8 140.3 154.4 161.4 170.1 179.2 174.5 182.8 190.4|188.3 196.9|200.1 Terminal Sacrifice
97 97 150PPM 91 89.9 106.5 122.6 137.6 154.2 157.2 164.6 171.9 175.3 177 184.2|186.4 189.4|195.2 Terminal Sacrifice
98 98 150PPM 91 94.9 112.2 133 147.3 158.3 167 174.1 185.9 189.9 193.9 194.2|198.7 194.5|199.6 Terminal Sacrifice
99 99 150PPM 91 95.6 113.4 132.8 144.4 154.8 162.9 169.6 169.6 175.1 174.8 185.4|186.5 188.5|191.2 Terminal Sacrifice
100 100 150PPM 91 101.7 116.9 133.5 144.9 154 156.9 164.1 168.7 180.7 175.5 186.6|187.2 190.2|194.8 Terminal Sacrifice
111 111 300PPM 91 77.4 93.4 110.6 121.5 135.3 141.4 150.6 156.9 160.7 164.6 163.7|166.1 169.6|173.9 Terminal Sacrifice
112 112 300PPM 91 77.9 91.6 104 116.2 123 136.5 142.7 151.4 154.5 163.3 163.1|164.5 169.8|173.7 Terminal Sacrifice
113 113 300PPM 91 69.9 80.2 100.8 106.9 120 126.9 136.7 139.2 144.8 149.5 153.1|154 157.7|159.4 Terminal Sacrifice
114 114 300PPM 91 84.8 97.7 113.8 122.7 137.6 142.3 151.1 159.7 161.8 167.8 170.4|173.8 180|181.2 Terminal Sacrifice
115 115 300PPM 91 89.1 100.6 118.4 132.4 141.7 150.2 162.5 161.6 167.8 170.7 181.9|183.8 189.8|194 Terminal Sacrifice
116 116 300PPM 91 91 100.4 114.8 125.1 134 139.6 150.2 156.3 157.7 162.8 167.5|170.6 173.4|176 Terminal Sacrifice
117 117 300PPM 91 94.3 104.6 118.5 129.9 136.9 144.7 151.8 159.8 158.4 163.2 167.7|170.2 176.5|177.2 Terminal Sacrifice
118 118 300PPM 91 91.9 102.2 122.8 130.4 140.1 148 157 159.5 169.4 168.1 176.4|175.5 180.1|181.8 Terminal Sacrifice
119 119 300PPM 91 98.7 106.1 113.5 124 134.3 145.5 151.4 157.4 163.4 165.9 171.2|174 173.1|178.3 Terminal Sacrifice
120 120 300PPM 91 103.4 108.7 126.3 135.9 145.5 155.6 165.6 170.7 170.4 175.8 184.5|187.6 186|194.4 Terminal Sacrifice
* All body weights in grams