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Short-Term Study Body Weights

Study Information:

Chemical Name: Milk thistle extract
CASRN: ="84604-20-6"
Study Number: C20008
Exposure Route: DOSED FEED
TDMS Number: 2000801
Sex: Female
Strain and Species: F 344/N Rats

Table Instructions and Notes:
Multiple body weights in a single week are displayed in one cell separated by "|". Values displayed may not match report summary values due to individual values being excluded in some cases.
Animal Number Cage Number Dose Group Days On Study Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Removal Reason
61 13 Untreated Control 93 82.1 105.2 120 130.2 139.7 146.1 151.6 157.4 160.2 164.9 166.2 170.3 170.1 171.9 Terminal Sacrifice
62 13 Untreated Control 93 75 106.3 125.8 139.8 156.6 161.6 167.9 175.5 177.8 184.1 184.5 192.5 190.6 198.3 Terminal Sacrifice
63 13 Untreated Control 93 77.8 109.4 123.8 139.7 156 157.2 164.8 169 178.6 178.3 181.7 184.6 186.9 195 Terminal Sacrifice
64 13 Untreated Control 93 86.3 112.1 130 143.3 157 159.5 166.8 172.3 179.2 184.7 187.4 189.3 187.5 190.8 Terminal Sacrifice
65 13 Untreated Control 93 84 115.9 135.9 149 162.3 170.1 180.9 187.4 192.4 196.2 199.7 204.1 202.3 207.8 Terminal Sacrifice
66 14 Untreated Control 93 86.9 107.5 124.8 132.8 143 148.8 153 156.7 162.5 163.5 164.2 169.6 169.2 172.8 Terminal Sacrifice
67 14 Untreated Control 93 81.7 114.1 134.1 147.5 161.7 166.2 174.2 183 189.7 195.5 195.4 203 201.3 208 Terminal Sacrifice
68 14 Untreated Control 93 89.2 115.3 131.8 147.5 159.5 165.9 173.1 182.5 189.1 193 194.4 202.2 198.5 208.7 Terminal Sacrifice
69 14 Untreated Control 93 78 108.3 127.4 138.7 154 160.7 164.8 176 180.6 185.9 185.5 192.8 188.6 189.9 Terminal Sacrifice
70 14 Untreated Control 93 79 102.4 122.7 133.6 143 150.9 154.7 161.7 166.3 170.9 174.7 178 179.2 184.1 Terminal Sacrifice
71 15 3125PPM 93 83.6 112.5 128.5 142.3 152.1 164.2 172.9 180.7 186.6 188.1 193.6 199 200.1 208.9 Terminal Sacrifice
72 15 3125PPM 93 91.6 121.8 138.4 153.6 149.5 174.9 183.4 188.7 195.2 195.5 200.2 201.3 209.7 207.8 Terminal Sacrifice
73 15 3125PPM 93 74 93.7 108.5 116.4 128.4 132 139.3 142.5 145.1 147.5 148.7 152.4 152.8 156.9 Terminal Sacrifice
74 15 3125PPM 93 87.2 112.7 130.5 142.6 142.9 163.6 175.4 178.3 183.8 184 187.4 192.9 189.6 197 Terminal Sacrifice
75 15 3125PPM 93 77.7 102.9 121.4 130.6 144.3 153.7 157.2 165.3 172.2 174.1 176.8 176.7 183.4 187 Terminal Sacrifice
76 16 3125PPM 93 76.6 101.4 117.1 125 127 142 147 150.7 154.5 158.1 156.7 163.5 161.1 167.8 Terminal Sacrifice
77 16 3125PPM 93 76.7 105.5 125.1 137.5 140.5 154.6 167 170.9 171.9 179.1 181.7 184.8 189 195.6 Terminal Sacrifice
78 16 3125PPM 93 83.9 113.4 127 139.9 129.7 157.1 165.6 169.1 175.2 176.6 179.9 185.2 183.8 188 Terminal Sacrifice
79 16 3125PPM 93 87.2 116.6 133 142.8 145.3 161.2 173 179.3 181.3 184.9 184.6 190.8 191.2 196.8 Terminal Sacrifice
80 16 3125PPM 93 89.3 115.1 127.1 137.6 139.6 151.6 163.7 167.5 170.8 172.4 179.1 178.5 183.3 186.7 Terminal Sacrifice
81 17 6250PPM 93 75.4 104.4 122 136.7 128.4 152.1 161.5 166.8 167.6 173.5 173.3 179 183.4 188.5 Terminal Sacrifice
82 17 6250PPM 93 87.7 109.1 124.9 133.4 143.3 156.2 161.5 169.3 175.6 177.7 180.1 186.5 191.9 196 Terminal Sacrifice
83 17 6250PPM 93 80.7 104 120.7 131.8 133.5 149.8 154.5 158.8 164.7 169.8 171.3 175.2 177.7 181.6 Terminal Sacrifice
84 17 6250PPM 93 76.9 111.6 127 142.1 129.4 161.8 170.9 182.9 184.5 190 192.1 192.9 196.6 199.9 Terminal Sacrifice
85 17 6250PPM 93 79.3 111.7 130.1 142.9 130.5 160.6 174.4 178.3 182 185.5 188.1 195.2 193.8 202 Terminal Sacrifice
86 18 6250PPM 93 80.2 104.5 116.8 132 144.3 149.5 163.3 164.9 171.6 172.5 172.7 180.9 179 189.3 Terminal Sacrifice
87 18 6250PPM 93 76.2 105.6 118.6 134.2 146 150 163.1 164.9 170.7 173.8 177.1 178.5 179.2 183.1 Terminal Sacrifice
88 18 6250PPM 93 82.5 108.3 125.5 135.2 147.2 152.8 161.8 161.7 165.1 169.1 168.6 171.6 172.5 174.3 Terminal Sacrifice
89 18 6250PPM 93 78.9 108.8 122.8 135.1 143.8 153.8 160.8 165 168.1 167.7 172.8 177.8 179.2 179.7 Terminal Sacrifice
90 18 6250PPM 93 88.7 115.1 133 139.3 155.7 159.8 173.3 178.9 181.3 185.2 187.5 192.7 189.6 197 Terminal Sacrifice
91 19 12500PPM 93 74.9 107.7 130.9 143.1 146.6 165.5 175.5 182.4 190.5 190.7 193.5 196.4 195.9 203.4 Terminal Sacrifice
92 19 12500PPM 93 90 118.1 134.2 144.5 153.9 162.5 172.3 180.4 183.9 182.8 184.2 187.3 188.5 191.6 Terminal Sacrifice
93 19 12500PPM 93 83.1 115.8 133.2 143.7 155.9 160.9 171.8 178.2 187.9 189.6 189.2 196.9 198.8 198.2 Terminal Sacrifice
94 19 12500PPM 93 80.1 108.6 128.4 139.6 136.9 155.4 157.9 168.6 172.6 174.6 177.9 181.1 186.4 189.6 Terminal Sacrifice
95 19 12500PPM 93 88.2 117 135.1 146.5 146 163.3 175.8 183.9 185.6 188.7 190.9 192.7 197.8 198.2 Terminal Sacrifice
96 20 12500PPM 93 79.5 102.7 118.8 132 118.3 150.1 159.8 164.5 166.9 171.1 171.6 170.6 179.2 181.2 Terminal Sacrifice
97 20 12500PPM 93 84.9 109.2 124.1 132.8 118.5 148.7 151.2 161.1 161.9 170.3 165.9 174.3 174.9 172.3 Terminal Sacrifice
98 20 12500PPM 93 85 112.1 130.6 139.3 126 161 165 173.3 181.5 179.3 187.5 190.4 188.5 190.6 Terminal Sacrifice
99 20 12500PPM 93 75.9 106.9 129.4 142.4 126.6 159.4 169.8 176.7 185.2 187.8 190.5 192.7 198.9 201.1 Terminal Sacrifice
100 20 12500PPM 93 75.9 107.3 128.1 138.9 124.1 154 162.3 171.4 175.5 179.4 181 182.7 186.3 186.6 Terminal Sacrifice
101 21 25000PPM 93 80.8 109.6 129.8 141.2 153.2 166.1 168.2 180.5 182.7 186.9 189.3 198 197.4 196.7 Terminal Sacrifice
102 21 25000PPM 93 84.9 110.1 123.8 133.7 150 156.5 164 171.6 171.6 174.7 179.6 185.4 183.6 184.3 Terminal Sacrifice
103 21 25000PPM 93 83.9 115.9 131.6 147.4 162.3 168.7 175.9 180.8 185.5 186.1 189.6 193.6 191.9 193.9 Terminal Sacrifice
104 21 25000PPM 93 88.6 111.4 125.6 135.4 146.9 156.2 163.7 168.6 171.8 178.9 181 186.1 187.8 190.4 Terminal Sacrifice
105 21 25000PPM 93 77.5 107 126.1 137.4 151.5 152.2 164.5 169.2 177.1 180.8 180.8 187.3 182.1 190.6 Terminal Sacrifice
106 22 25000PPM 93 87 106.2 119.2 127.3 114.1 142.3 148.3 155.1 162.2 163.1 169.1 178.7 181 191.5 Terminal Sacrifice
107 22 25000PPM 93 77.1 107.5 127.6 140.3 125.3 163 170.6 178.4 181.5 184.8 189.1 191.2 197.4 200.9 Terminal Sacrifice
108 22 25000PPM 93 85.9 111.6 129.5 139.5 123.8 159.8 167.9 174.9 182.6 182 188.1 191.8 198.3 196.4 Terminal Sacrifice
109 22 25000PPM 93 77 106.6 125.1 133.7 120.5 149.2 155.6 165.3 166.9 172.5 173.6 183.4 185.1 187 Terminal Sacrifice
110 22 25000PPM 93 81.2 107.4 126.2 137.3 122.7 159 163.5 174.5 179.2 178.3 181 186.8 190.8 190.2 Terminal Sacrifice
111 23 50000PPM 93 77.1 99.9 119.6 133.3 122.3 151.9 162.1 169.6 173 177.6 180.5 184.4 184.2 185.8 Terminal Sacrifice
112 23 50000PPM 93 90.5 110.9 127.8 139.2 125.4 156.6 164.9 170.9 177.5 181.5 183.3 186.5 188.4 194.7 Terminal Sacrifice
113 23 50000PPM 93 89.5 111.3 125.2 136.2 119.5 153.2 160.9 171.4 176.6 177.3 180.4 186.4 186.9 192 Terminal Sacrifice
114 23 50000PPM 93 81.1 106.6 122.3 136.2 125.3 156.3 160.3 168.8 170.2 179.6 179.2 183.7 182.9 182.2 Terminal Sacrifice
115 23 50000PPM 93 73.7 90.8 105.2 114.6 113.3 129 132.5 136.8 139.9 140.7 144.3 147.4 150 153.3 Terminal Sacrifice
116 24 50000PPM 93 89 109.3 124.6 135.1 143.3 151 153.1 162.8 171.3 172.3 180.8 183.6 187.1 194.6 Terminal Sacrifice
117 24 50000PPM 93 76.1 100.8 119.2 132 129.4 146.8 155.8 161.7 166.8 168.6 168.3 178.8 181.9 184.1 Terminal Sacrifice
118 24 50000PPM 93 88.5 113.4 127.2 139 139.4 154.6 160.9 169.2 176 177.5 185.2 192.2 193 199.2 Terminal Sacrifice
119 24 50000PPM 93 73.6 100.4 118.4 133 145.6 150.9 160.9 166.6 173.3 178.8 179.9 188.1 185.1 189.4 Terminal Sacrifice
120 24 50000PPM 93 79.9 99.2 114.8 122.7 123.9 138.3 143.5 150.4 153.1 158.3 163.2 166.3 168.9 166.8 Terminal Sacrifice
* All body weights in grams